Published in Am J Physiol Lung Cell Mol Physiol on October 29, 2004
Acute Respiratory Distress Syndrome Clinical Network (ARDSNet) | NCT00000579
Clinical and Biological Markers in Acute Respiratory Failure | NCT02019095
Plasma receptor for advanced glycation end products and clinical outcomes in acute lung injury. Thorax (2008) 3.13
Acute lung injury and the acute respiratory distress syndrome: four decades of inquiry into pathogenesis and rational management. Am J Respir Cell Mol Biol (2005) 2.93
Trauma-associated lung injury differs clinically and biologically from acute lung injury due to other clinical disorders. Crit Care Med (2007) 2.79
Subphenotypes in acute respiratory distress syndrome: latent class analysis of data from two randomised controlled trials. Lancet Respir Med (2014) 2.44
Beyond mortality: future clinical research in acute lung injury. Am J Respir Crit Care Med (2010) 2.28
Role of TNFalpha in pulmonary pathophysiology. Respir Res (2006) 2.27
Prognostic and pathogenetic value of combining clinical and biochemical indices in patients with acute lung injury. Chest (2009) 2.17
Plasma biomarker profiles in acute exacerbation of idiopathic pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol (2010) 2.03
The association between BMI and plasma cytokine levels in patients with acute lung injury. Chest (2010) 1.75
Predictive and pathogenetic value of plasma biomarkers for acute kidney injury in patients with acute lung injury. Crit Care Med (2007) 1.73
Circulating angiopoietin 2 correlates with mortality in a surgical population with acute lung injury/adult respiratory distress syndrome. Shock (2008) 1.62
Soluble intercellular adhesion molecule-1 and clinical outcomes in patients with acute lung injury. Intensive Care Med (2008) 1.61
Plasma granulocyte colony-stimulating factor levels correlate with clinical outcomes in patients with acute lung injury. Crit Care Med (2009) 1.47
Pathogenetic significance of biological markers of ventilator-associated lung injury in experimental and clinical studies. Chest (2006) 1.45
Cytokine release following recruitment maneuvers. Chest (2007) 1.45
Retracted Gene expression profiles analysis identifies key genes for acute lung injury in patients with sepsis. Diagn Pathol (2014) 1.37
Use of risk reclassification with multiple biomarkers improves mortality prediction in acute lung injury. Crit Care Med (2011) 1.31
Identification of early acute lung injury at initial evaluation in an acute care setting prior to the onset of respiratory failure. Chest (2009) 1.28
Simple biologically informed inflammatory index of two serum cytokines predicts 10 year all-cause mortality in older adults. J Gerontol A Biol Sci Med Sci (2013) 1.25
Biomarkers in acute lung injury: insights into the pathogenesis of acute lung injury. Crit Care Clin (2011) 1.23
Higher urine desmosine levels are associated with mortality in patients with acute lung injury. Am J Physiol Lung Cell Mol Physiol (2006) 1.18
Biomarkers in acute lung injury. Transl Res (2012) 1.11
Discovery of the gene signature for acute lung injury in patients with sepsis. Physiol Genomics (2009) 1.10
Biological markers of lung injury before and after the institution of positive pressure ventilation in patients with acute lung injury. Crit Care (2006) 1.03
Acute respiratory distress syndrome: A clinical review. Pulm Circ (2011) 1.02
Associations of markers of inflammation and coagulation with delirium during critical illness. Intensive Care Med (2012) 1.02
IL-1beta augments TNF-alpha-mediated inflammatory responses from lung epithelial cells. J Interferon Cytokine Res (2009) 0.99
Plasma neutrophil elastase and elafin imbalance is associated with acute respiratory distress syndrome (ARDS) development. PLoS One (2009) 0.98
Plasma C-reactive protein levels are associated with improved outcome in ARDS. Chest (2009) 0.97
Tumor necrosis factor-alpha from macrophages enhances LPS-induced clara cell expression of keratinocyte-derived chemokine. Am J Respir Cell Mol Biol (2007) 0.95
Biomarkers in acute lung injury--marking forward progress. Crit Care Clin (2011) 0.95
Selective inhibition of intra-alveolar p55 TNF receptor attenuates ventilator-induced lung injury. Thorax (2011) 0.95
The Esophageal Pressure-Guided Ventilation 2 (EPVent2) trial protocol: a multicentre, randomised clinical trial of mechanical ventilation guided by transpulmonary pressure. BMJ Open (2014) 0.92
Parenchymal cell TNF receptors contribute to inflammatory cell recruitment and respiratory failure in Pneumocystis carinii-induced pneumonia. J Immunol (2008) 0.90
Tumour necrosis factor receptor 1 and mortality in a multi-ethnic cohort: the Northern Manhattan Study. Age Ageing (2013) 0.89
Growth differentiation factor-15 and prognosis in acute respiratory distress syndrome: a retrospective cohort study. Crit Care (2013) 0.89
Characterization of TNF receptor subtype expression and signaling on pulmonary endothelial cells in mice. Am J Physiol Lung Cell Mol Physiol (2011) 0.85
The roles of TNF-alpha and the soluble TNF receptor I on sleep architecture in OSA. Sleep Breath (2009) 0.84
Augmentation of Pulmonary Epithelial Cell IL-8 Expression and Permeability by Pre-B-cell Colony Enhancing Factor. J Inflamm (Lond) (2008) 0.84
Sources of alveolar soluble TNF receptors during acute lung injury of different etiologies. J Appl Physiol (1985) (2011) 0.84
Proteomic profiles in acute respiratory distress syndrome differentiates survivors from non-survivors. PLoS One (2014) 0.84
Continuous monitoring of the bronchial epithelial lining fluid by microdialysis. Respir Res (2007) 0.83
Bench-to-bedside review: Ventilation-induced renal injury through systemic mediator release--just theory or a causal relationship? Crit Care (2011) 0.81
Ultrastructural study of alveolar epithelial type II cells by high-frequency oscillatory ventilation. Biomed Res Int (2013) 0.80
Age-related differences in biomarkers of acute inflammation during hospitalization for sepsis. Shock (2014) 0.80
Biomarkers of acute lung injury: worth their salt? BMC Med (2011) 0.80
Prognostic significance of elevated cardiac troponin-T levels in acute respiratory distress syndrome patients. PLoS One (2012) 0.79
Effect of high advanced glycation end-product diet on pulmonary inflammatory response and pulmonary function following gastric aspiration. Shock (2012) 0.79
Respiratory mechanics and plasma levels of tumor necrosis factor alpha and interleukin 6 are affected by gas humidification during mechanical ventilation in dogs. PLoS One (2014) 0.79
Long-term home noninvasive mechanical ventilation increases systemic inflammatory response in chronic obstructive pulmonary disease: a prospective observational study. Mediators Inflamm (2014) 0.79
Microarray meta-analysis identifies acute lung injury biomarkers in donor lungs that predict development of primary graft failure in recipients. PLoS One (2012) 0.78
Thrombocytopenia is associated with acute respiratory distress syndrome mortality: an international study. PLoS One (2014) 0.76
Markers of inflammation and coagulation may be modulated by enteral feeding strategy. JPEN J Parenter Enteral Nutr (2012) 0.76
Death receptors mediate the adverse effects of febrile-range hyperthermia on the outcome of lipopolysaccharide-induced lung injury. Am J Physiol Lung Cell Mol Physiol (2011) 0.76
A Pathophysiologic Approach to Biomarkers in Acute Respiratory Distress Syndrome. Dis Markers (2016) 0.75
Analysis of mechanical ventilation and lipopolysaccharide‑induced acute lung injury using DNA microarray analysis. Mol Med Rep (2015) 0.75
Incorporating Inflammation into Mortality Risk in Pediatric Acute Respiratory Distress Syndrome. Crit Care Med (2017) 0.75
Anti-TNFα Therapy in Inflammatory Lung Diseases bn. Pharmacol Ther (2017) 0.75
Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network. N Engl J Med (2000) 48.03
Higher versus lower positive end-expiratory pressures in patients with the acute respiratory distress syndrome. N Engl J Med (2004) 11.78
Lebrikizumab treatment in adults with asthma. N Engl J Med (2011) 8.07
Pulmonary dead-space fraction as a risk factor for death in the acute respiratory distress syndrome. N Engl J Med (2002) 6.17
Lower tidal volume ventilation and plasma cytokine markers of inflammation in patients with acute lung injury. Crit Care Med (2005) 5.76
Intrapulmonary delivery of bone marrow-derived mesenchymal stem cells improves survival and attenuates endotoxin-induced acute lung injury in mice. J Immunol (2007) 5.66
The acute respiratory distress syndrome. J Clin Invest (2012) 5.61
Randomized, placebo-controlled clinical trial of an aerosolized β₂-agonist for treatment of acute lung injury. Am J Respir Crit Care Med (2011) 5.24
An official American Thoracic Society workshop report: features and measurements of experimental acute lung injury in animals. Am J Respir Cell Mol Biol (2011) 4.65
The outcome of neutrophil gelatinase-associated lipocalin-positive subclinical acute kidney injury: a multicenter pooled analysis of prospective studies. J Am Coll Cardiol (2011) 4.57
An official American Thoracic Society public policy statement: Novel risk factors and the global burden of chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2010) 3.92
Recent trends in acute lung injury mortality: 1996-2005. Crit Care Med (2009) 3.86
Allogeneic human mesenchymal stem cells for treatment of E. coli endotoxin-induced acute lung injury in the ex vivo perfused human lung. Proc Natl Acad Sci U S A (2009) 3.84
Prevention of ventilator-associated pneumonia: an evidence-based systematic review. Ann Intern Med (2003) 3.74
Acute traumatic coagulopathy: initiated by hypoperfusion: modulated through the protein C pathway? Ann Surg (2007) 3.49
Rosuvastatin for sepsis-associated acute respiratory distress syndrome. N Engl J Med (2014) 3.39
Clinical risk factors for primary graft dysfunction after lung transplantation. Am J Respir Crit Care Med (2013) 3.38
Receptor for advanced glycation end-products is a marker of type I cell injury in acute lung injury. Am J Respir Crit Care Med (2006) 3.38
Pathogenetic and prognostic significance of altered coagulation and fibrinolysis in acute lung injury/acute respiratory distress syndrome. Crit Care Med (2007) 3.31
Association between cell-free hemoglobin, acetaminophen, and mortality in patients with sepsis: an observational study. Crit Care Med (2013) 3.30
Randomized clinical trial of activated protein C for the treatment of acute lung injury. Am J Respir Crit Care Med (2008) 3.28
Effect of prone positioning on clinical outcomes in children with acute lung injury: a randomized controlled trial. JAMA (2005) 3.21
Transfusion-related acute lung injury: incidence and risk factors. Blood (2011) 3.12
Platelet depletion and aspirin treatment protect mice in a two-event model of transfusion-related acute lung injury. J Clin Invest (2009) 3.08
Polymorphonuclear leukocytes mediate Staphylococcus aureus Panton-Valentine leukocidin-induced lung inflammation and injury. Proc Natl Acad Sci U S A (2010) 3.05
Nonventilatory treatments for acute lung injury and ARDS. Chest (2007) 3.02
Elevated levels of plasminogen activator inhibitor-1 in pulmonary edema fluid are associated with mortality in acute lung injury. Am J Physiol Lung Cell Mol Physiol (2003) 3.02
Postobstructive pulmonary edema: a case for hydrostatic mechanisms. Chest (2007) 2.97
Cytokine-mediated inflammation in acute lung injury. Cytokine Growth Factor Rev (2003) 2.95
Inflammasome-regulated cytokines are critical mediators of acute lung injury. Am J Respir Crit Care Med (2012) 2.92
COPD and incident cardiovascular disease hospitalizations and mortality: Kaiser Permanente Medical Care Program. Chest (2005) 2.88
Neutrophil extracellular traps are pathogenic in primary graft dysfunction after lung transplantation. Am J Respir Crit Care Med (2015) 2.80
Trauma-associated lung injury differs clinically and biologically from acute lung injury due to other clinical disorders. Crit Care Med (2007) 2.79
Urine neutrophil gelatinase-associated lipocalin moderately predicts acute kidney injury in critically ill adults. J Am Soc Nephrol (2009) 2.77
Atrial Fibrillation Is an Independent Predictor of Mortality in Critically Ill Patients. Crit Care Med (2015) 2.77
Antibacterial effect of human mesenchymal stem cells is mediated in part from secretion of the antimicrobial peptide LL-37. Stem Cells (2010) 2.72
Subglottic secretion drainage for preventing ventilator-associated pneumonia: a meta-analysis. Am J Med (2005) 2.67
Clinically relevant concentrations of beta2-adrenergic agonists stimulate maximal cyclic adenosine monophosphate-dependent airspace fluid clearance and decrease pulmonary edema in experimental acid-induced lung injury. Crit Care Med (2004) 2.66
Mesenchymal stem cells and idiopathic pulmonary fibrosis. Potential for clinical testing. Am J Respir Crit Care Med (2013) 2.66
Hyperoxia causes angiopoietin 2-mediated acute lung injury and necrotic cell death. Nat Med (2006) 2.63
Effects of recruitment maneuvers in patients with acute lung injury and acute respiratory distress syndrome ventilated with high positive end-expiratory pressure. Crit Care Med (2003) 2.63
Clinical practice. Acute pulmonary edema. N Engl J Med (2005) 2.62
Higher urine nitric oxide is associated with improved outcomes in patients with acute lung injury. Am J Respir Crit Care Med (2006) 2.61
Comparison of the SpO2/FIO2 ratio and the PaO2/FIO2 ratio in patients with acute lung injury or ARDS. Chest (2007) 2.58
Transfusion-related acute lung injury: a review. Chest (2004) 2.56
Acute kidney injury in patients with acute lung injury: impact of fluid accumulation on classification of acute kidney injury and associated outcomes. Crit Care Med (2011) 2.55
Simvastatin decreases lipopolysaccharide-induced pulmonary inflammation in healthy volunteers. Am J Respir Crit Care Med (2009) 2.52
Pediatric acute lung injury: prospective evaluation of risk factors associated with mortality. Am J Respir Crit Care Med (2004) 2.51
Neutrophils and their Fc gamma receptors are essential in a mouse model of transfusion-related acute lung injury. J Clin Invest (2006) 2.50
Significance of von Willebrand factor in septic and nonseptic patients with acute lung injury. Am J Respir Crit Care Med (2004) 2.49
Pharmacotherapy of acute lung injury and the acute respiratory distress syndrome. J Intensive Care Med (2006) 2.47
Plasma levels of receptor for advanced glycation end products, blood transfusion, and risk of primary graft dysfunction. Am J Respir Crit Care Med (2009) 2.43
Prolonged hypoxia differentially regulates hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha expression in lung epithelial cells: implication of natural antisense HIF-1alpha. J Biol Chem (2004) 2.42
Bronchial secretory immunoglobulin a deficiency correlates with airway inflammation and progression of chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2011) 2.42
Concise review: Mesenchymal stem cells for acute lung injury: role of paracrine soluble factors. Stem Cells (2011) 2.41
Low tidal volume reduces epithelial and endothelial injury in acid-injured rat lungs. Am J Respir Crit Care Med (2002) 2.40
Ligation of protease-activated receptor 1 enhances alpha(v)beta6 integrin-dependent TGF-beta activation and promotes acute lung injury. J Clin Invest (2006) 2.40
Prehospital statin and aspirin use and the prevalence of severe sepsis and acute lung injury/acute respiratory distress syndrome. Crit Care Med (2011) 2.40
Endoplasmic reticulum stress in alveolar epithelial cells is prominent in IPF: association with altered surfactant protein processing and herpesvirus infection. Am J Physiol Lung Cell Mol Physiol (2008) 2.39
Active and passive cigarette smoking and acute lung injury after severe blunt trauma. Am J Respir Crit Care Med (2011) 2.39
Protein C and thrombomodulin in human acute lung injury. Am J Physiol Lung Cell Mol Physiol (2003) 2.37
Biological markers of acute kidney injury. J Am Soc Nephrol (2011) 2.36
Therapeutic effects of human mesenchymal stem cells in ex vivo human lungs injured with live bacteria. Am J Respir Crit Care Med (2013) 2.34
Fas and fas ligand are up-regulated in pulmonary edema fluid and lung tissue of patients with acute lung injury and the acute respiratory distress syndrome. Am J Pathol (2002) 2.30
Beyond mortality: future clinical research in acute lung injury. Am J Respir Crit Care Med (2010) 2.28
Alveolar epithelial ion and fluid transport: recent progress. Am J Respir Cell Mol Biol (2006) 2.20
Informed consent in research to improve the number and quality of deceased donor organs. Crit Care Med (2011) 2.18
Plasma angiopoietin-2 predicts the onset of acute lung injury in critically ill patients. Am J Respir Crit Care Med (2013) 2.17
Prognostic and pathogenetic value of combining clinical and biochemical indices in patients with acute lung injury. Chest (2009) 2.17
Management of the critically ill patient with severe acute pancreatitis. Crit Care Med (2004) 2.16
Racial and ethnic disparities in mortality from acute lung injury. Crit Care Med (2009) 2.14
Therapeutic strategies for severe acute lung injury. Crit Care Med (2010) 2.12
Direct visual instillation as a method for efficient delivery of fluid into the distal airspaces of anesthetized mice. Exp Lung Res (2004) 2.12
Obesity and primary graft dysfunction after lung transplantation: the Lung Transplant Outcomes Group Obesity Study. Am J Respir Crit Care Med (2011) 2.11
A comprehensive study of the direct and indirect costs of adult asthma. J Allergy Clin Immunol (2003) 2.11
Keratinocyte and hepatocyte growth factors in the lung: roles in lung development, inflammation, and repair. Am J Physiol Lung Cell Mol Physiol (2002) 2.10
Timing of Intubation and Clinical Outcomes in Adults With Acute Respiratory Distress Syndrome. Crit Care Med (2016) 2.08
Sugar administration is an effective adjunctive therapy in the treatment of Pseudomonas aeruginosa pneumonia. Am J Physiol Lung Cell Mol Physiol (2013) 2.04
Plasma biomarker profiles in acute exacerbation of idiopathic pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol (2010) 2.03
Procoagulant alveolar microparticles in the lungs of patients with acute respiratory distress syndrome. Am J Physiol Lung Cell Mol Physiol (2009) 2.03