Published in Crit Care Med on August 01, 2007
Activated Protein C to Treat Acute Lung Injuries | NCT00112164
Clinical and Biological Markers in Acute Respiratory Failure | NCT02019095
Low-Dose Tenecteplase in Covid-19 Diagnosed With Pulmonary Embolism | NCT04558125
Randomized clinical trial of activated protein C for the treatment of acute lung injury. Am J Respir Crit Care Med (2008) 3.28
Subphenotypes in acute respiratory distress syndrome: latent class analysis of data from two randomised controlled trials. Lancet Respir Med (2014) 2.44
Beyond mortality: future clinical research in acute lung injury. Am J Respir Crit Care Med (2010) 2.28
A phase II randomized placebo-controlled trial of omega-3 fatty acids for the treatment of acute lung injury. Crit Care Med (2011) 2.27
Prognostic and pathogenetic value of combining clinical and biochemical indices in patients with acute lung injury. Chest (2009) 2.17
ABO blood type A is associated with increased risk of ARDS in whites following both major trauma and severe sepsis. Chest (2014) 2.07
Plasma biomarker profiles in acute exacerbation of idiopathic pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol (2010) 2.03
Clara cell protein (CC16), a marker of lung epithelial injury, is decreased in plasma and pulmonary edema fluid from patients with acute lung injury. Chest (2009) 2.02
Procoagulant signalling mechanisms in lung inflammation and fibrosis: novel opportunities for pharmacological intervention? Br J Pharmacol (2008) 1.80
Acute lung injury: epidemiology, pathogenesis, and treatment. J Aerosol Med Pulm Drug Deliv (2010) 1.78
Persisting high levels of plasma pentraxin 3 over the first days after severe sepsis and septic shock onset are associated with mortality. Intensive Care Med (2010) 1.75
The association between BMI and plasma cytokine levels in patients with acute lung injury. Chest (2010) 1.75
Predictive and pathogenetic value of plasma biomarkers for acute kidney injury in patients with acute lung injury. Crit Care Med (2007) 1.73
Biomarkers of inflammation, coagulation and fibrinolysis predict mortality in acute lung injury. Crit Care (2008) 1.69
ANGPT2 genetic variant is associated with trauma-associated acute lung injury and altered plasma angiopoietin-2 isoform ratio. Am J Respir Crit Care Med (2011) 1.62
Neither fibrin nor plasminogen activator inhibitor-1 deficiency protects lung function in a mouse model of acute lung injury. Am J Physiol Lung Cell Mol Physiol (2008) 1.62
Role of coagulation pathways and treatment with activated protein C in hyperoxic lung injury. Thorax (2008) 1.58
Plasma granulocyte colony-stimulating factor levels correlate with clinical outcomes in patients with acute lung injury. Crit Care Med (2009) 1.47
Clinical characteristics and outcomes of sepsis-related vs non-sepsis-related ARDS. Chest (2010) 1.43
Distinct molecular phenotypes of direct vs indirect ARDS in single-center and multicenter studies. Chest (2015) 1.31
Use of risk reclassification with multiple biomarkers improves mortality prediction in acute lung injury. Crit Care Med (2011) 1.31
Identification of early acute lung injury at initial evaluation in an acute care setting prior to the onset of respiratory failure. Chest (2009) 1.28
Biomarkers in acute lung injury: insights into the pathogenesis of acute lung injury. Crit Care Clin (2011) 1.23
Elevated PAI-1 is associated with poor clinical outcomes in pediatric patients with acute lung injury. Intensive Care Med (2009) 1.14
Treatment of acute respiratory distress syndrome with allogeneic adipose-derived mesenchymal stem cells: a randomized, placebo-controlled pilot study. Respir Res (2014) 1.09
Activated protein C protects against ventilator-induced pulmonary capillary leak. Am J Physiol Lung Cell Mol Physiol (2009) 1.09
Clinical review: Early treatment of acute lung injury--paradigm shift toward prevention and treatment prior to respiratory failure. Crit Care (2012) 1.07
Protective mechanisms of activated protein C in severe inflammatory disorders. Br J Pharmacol (2009) 1.07
Lung Injury Prevention with Aspirin (LIPS-A): a protocol for a multicentre randomised clinical trial in medical patients at high risk of acute lung injury. BMJ Open (2012) 1.05
Pathogenetic and predictive value of biomarkers in patients with ALI and lower severity of illness: results from two clinical trials. Am J Physiol Lung Cell Mol Physiol (2012) 1.05
4G/5G polymorphism of PAI-1 gene is associated with multiple organ dysfunction and septic shock in pneumonia induced severe sepsis: prospective, observational, genetic study. Crit Care (2010) 1.05
Anti-inflammatory and anticoagulative effects of paeonol on LPS-induced acute lung injury in rats. Evid Based Complement Alternat Med (2012) 1.03
Acute respiratory distress syndrome: A clinical review. Pulm Circ (2011) 1.02
Cytoprotective-selective activated protein C attenuates Pseudomonas aeruginosa-induced lung injury in mice. Am J Respir Cell Mol Biol (2011) 1.02
Inhaled activated protein C protects mice from ventilator-induced lung injury. Crit Care (2010) 1.00
Bacterial lipoprotein TLR2 agonists broadly modulate endothelial function and coagulation pathways in vitro and in vivo. J Immunol (2010) 1.00
The protein C pathway: implications for the design of the RESPOND study. Crit Care (2007) 0.96
Therapeutic modulation of coagulation and fibrinolysis in acute lung injury and the acute respiratory distress syndrome. Curr Pharm Biotechnol (2011) 0.96
Biomarkers in acute lung injury--marking forward progress. Crit Care Clin (2011) 0.95
Biomarkers in acute lung injury: are we making progress? Crit Care Med (2008) 0.95
Plasminogen activator inhibitor-1 regulates LPS-induced TLR4/MD-2 pathway activation and inflammation in alveolar macrophages. Inflammation (2015) 0.94
Blood transfusion during cardiac surgery is associated with inflammation and coagulation in the lung: a case control study. Crit Care (2011) 0.93
4G/5G polymorphism of plasminogen activator inhibitor-1 gene is associated with mortality in intensive care unit patients with severe pneumonia. Anesthesiology (2009) 0.92
The Esophageal Pressure-Guided Ventilation 2 (EPVent2) trial protocol: a multicentre, randomised clinical trial of mechanical ventilation guided by transpulmonary pressure. BMJ Open (2014) 0.92
High tidal volume mechanical ventilation-induced lung injury in rats is greater after acid instillation than after sepsis-induced acute lung injury, but does not increase systemic inflammation: an experimental study. BMC Anesthesiol (2011) 0.89
Platelets in the pathogenesis of acute respiratory distress syndrome. Am J Physiol Lung Cell Mol Physiol (2015) 0.88
Bioinformatics insights into acute lung injury/acute respiratory distress syndrome. Clin Transl Med (2012) 0.87
Inhibition of neutrophil apoptosis by PAI-1. Am J Physiol Lung Cell Mol Physiol (2011) 0.87
Platelets enhance endothelial adhesiveness in high tidal volume ventilation. Am J Respir Cell Mol Biol (2008) 0.87
Nebulized anticoagulants for acute lung injury - a systematic review of preclinical and clinical investigations. Crit Care (2012) 0.86
Hyaluronic Acid binding protein 2 is a novel regulator of vascular integrity. Arterioscler Thromb Vasc Biol (2009) 0.86
Impact of obesity on outcomes for patients hospitalised with pneumonia. Eur Respir J (2012) 0.86
Omega-3 fatty acids in critical illness. Nutr Rev (2010) 0.85
Proteomic profiles in acute respiratory distress syndrome differentiates survivors from non-survivors. PLoS One (2014) 0.84
Mesenchymal stem cells in acute lung injury: are they ready for translational medicine? J Cell Mol Med (2013) 0.82
Bench-to-bedside review: Ventilation-induced renal injury through systemic mediator release--just theory or a causal relationship? Crit Care (2011) 0.81
Predictive modeling and inflammatory biomarkers in rats with lung contusion and gastric aspiration. J Trauma (2009) 0.81
Biomarkers of acute lung injury: worth their salt? BMC Med (2011) 0.80
Postexposure aerosolized heparin reduces lung injury in chlorine-exposed mice. Am J Physiol Lung Cell Mol Physiol (2014) 0.80
Pulmonary vascular dysfunction in ARDS. Ann Intensive Care (2014) 0.80
Prognostic factors in the acute respiratory distress syndrome. Clin Transl Med (2015) 0.80
Assessment of Fibrinolysis in Sepsis Patients with Urokinase Modified Thromboelastography. PLoS One (2015) 0.80
Plasminogen activator inhibitor-1 regulates LPS induced inflammation in rat macrophages through autophagy activation. ScientificWorldJournal (2014) 0.80
Early intravenous unfractionated heparin and outcome in acute lung injury and acute respiratory distress syndrome: a retrospective propensity matched cohort study. BMC Pulm Med (2012) 0.79
Alcohol and inflammatory responses: Highlights of the 2015 Alcohol and Immunology Research Interest Group (AIRIG) meeting. Alcohol (2016) 0.79
Microarray meta-analysis identifies acute lung injury biomarkers in donor lungs that predict development of primary graft failure in recipients. PLoS One (2012) 0.78
Inhaled activated protein C: a novel therapy for acute lung injury? Crit Care (2009) 0.78
Plasminogen activator inhibitor-type I gene deficient mice show reduced influx of neutrophils in ventilator-induced lung injury. Crit Care Res Pract (2011) 0.78
Activation of Coagulation and Fibrinolysis in Acute Respiratory Distress Syndrome: A Prospective Pilot Study. Front Med (Lausanne) (2016) 0.78
Recombinant human activated protein C in the treatment of acute respiratory distress syndrome: a randomized clinical trial. PLoS One (2014) 0.77
Higher pulmonary dead space may predict prolonged mechanical ventilation after cardiac surgery. Pediatr Pulmonol (2009) 0.77
Kinetics and Role of Plasma Matrix Metalloproteinase-9 Expression in Acute Lung Injury and the Acute Respiratory Distress Syndrome. Shock (2015) 0.77
Protein Quantitative Trait Loci Analysis Identifies Genetic Variation in the Innate Immune Regulator TOLLIP in Post-Lung Transplant Primary Graft Dysfunction Risk. Am J Transplant (2015) 0.76
Markers of inflammation and coagulation may be modulated by enteral feeding strategy. JPEN J Parenter Enteral Nutr (2012) 0.76
Tissue plasminogen activator attenuates ventilator-induced lung injury in rats. Acta Pharmacol Sin (2012) 0.76
Protein biomarkers associated with primary graft dysfunction following lung transplantation. Am J Physiol Lung Cell Mol Physiol (2017) 0.75
Linking genetics to ARDS pathogenesis: the role of the platelet. Chest (2015) 0.75
The 4G/4G genotype of the PAI-1 (serpine-1) 4G/5G polymorphism is associated with decreased lung allograft utilization. Am J Transplant (2012) 0.75
A Pathophysiologic Approach to Biomarkers in Acute Respiratory Distress Syndrome. Dis Markers (2016) 0.75
Is there an association between hemostatic abnormalities and the outcome of acute lung injury? Crit Care Med (2007) 0.75
What is the clinical significance of pulmonary hypertension in acute respiratory distress syndrome? A review. Minerva Anestesiol (2013) 0.75
Biomarkers in Pediatric ARDS: Future Directions. Front Pediatr (2016) 0.75
Plasma Biomarker Analysis in Pediatric ARDS: Generating Future Framework from a Pilot Randomized Control Trial of Methylprednisolone: A Framework for Identifying Plasma Biomarkers Related to Clinical Outcomes in Pediatric ARDS. Front Pediatr (2016) 0.75
Plasminogen Activator Inhibitor-1 is Critical in Alcohol-enhanced Acute Lung Injury in Mice. Am J Respir Cell Mol Biol (2017) 0.75
Asiatic Acid Inhibits Lipopolysaccharide-Induced Acute Lung Injury in Mice. Inflammation (2016) 0.75
Network clusters analysis based on protein-protein interaction network constructed in phosgene-induced acute lung injury. Lung (2013) 0.75
Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network. N Engl J Med (2000) 48.03
Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med (2001) 27.70
The American-European Consensus Conference on ARDS. Definitions, mechanisms, relevant outcomes, and clinical trial coordination. Am J Respir Crit Care Med (1994) 27.68
The acute respiratory distress syndrome. N Engl J Med (2000) 25.38
The APACHE III prognostic system. Risk prediction of hospital mortality for critically ill hospitalized adults. Chest (1991) 16.06
Thrombin signalling and protease-activated receptors. Nature (2000) 9.27
Treating patients with severe sepsis. N Engl J Med (1999) 6.56
Alveolar fluid clearance is impaired in the majority of patients with acute lung injury and the acute respiratory distress syndrome. Am J Respir Crit Care Med (2001) 6.41
Attributable risk percent in case-control studies. Br J Prev Soc Med (1971) 5.21
Epidemiology and outcome of acute lung injury in European intensive care units. Results from the ALIVE study. Intensive Care Med (2003) 4.94
The N-terminal Pro-BNP investigation of dyspnea in the emergency department (PRIDE) study. Am J Cardiol (2005) 3.85
Depressed bronchoalveolar urokinase activity in patients with adult respiratory distress syndrome. N Engl J Med (1990) 3.04
Elevated levels of plasminogen activator inhibitor-1 in pulmonary edema fluid are associated with mortality in acute lung injury. Am J Physiol Lung Cell Mol Physiol (2003) 3.02
Alterations of the gas exchange apparatus in adult respiratory insufficiency associated with septicemia. Am Rev Respir Dis (1977) 2.90
The effect of joint exposure to alcohol and tobacco on risk of cancer of the mouth and pharynx. J Chronic Dis (1972) 2.86
Septic shock, multiple organ failure, and disseminated intravascular coagulation. Compared patterns of antithrombin III, protein C, and protein S deficiencies. Chest (1992) 2.80
Efficacy of low tidal volume ventilation in patients with different clinical risk factors for acute lung injury and the acute respiratory distress syndrome. Am J Respir Crit Care Med (2001) 2.57
Protein C and thrombomodulin in human acute lung injury. Am J Physiol Lung Cell Mol Physiol (2003) 2.37
Universal changes in biomarkers of coagulation and inflammation occur in patients with severe sepsis, regardless of causative micro-organism [ISRCTN74215569]. Crit Care (2004) 2.25
Biological markers of acute lung injury: prognostic and pathogenetic significance. Am J Respir Crit Care Med (1997) 2.10
Low levels of protein C are associated with poor outcome in severe sepsis. Chest (2001) 2.05
Drotrecogin alfa (activated) in the treatment of severe sepsis patients with multiple-organ dysfunction: data from the PROWESS trial. Intensive Care Med (2003) 2.05
Acute release of plasminogen activator inhibitor-1 in ST-segment elevation myocardial infarction predicts mortality. Circulation (2003) 1.94
Thrombin impairs alveolar fluid clearance by promoting endocytosis of Na+,K+-ATPase. Am J Respir Cell Mol Biol (2005) 1.91
Fibrinolytic factors and the risk of myocardial infarction or sudden death in patients with angina pectoris. ECAT Study Group. European Concerted Action on Thrombosis and Disabilities. Circulation (1996) 1.80
Coagulation abnormalities in acute lung injury and sepsis. Am J Respir Cell Mol Biol (2000) 1.72
Time course of hemostatic abnormalities in sepsis and its relation to outcome. Chest (1993) 1.72
Patients with severe sepsis vary markedly in their ability to generate activated protein C. Blood (2004) 1.67
Serial abnormalities of fibrin turnover in evolving adult respiratory distress syndrome. Am J Physiol (1991) 1.54
Treatment of ARDS. Chest (2001) 1.37
Plasminogen activator inhibitor-1 impairs alveolar epithelial repair by binding to vitronectin. Am J Respir Cell Mol Biol (2004) 1.34
Activated protein C decreases plasminogen activator-inhibitor activity in endothelial cell-conditioned medium. Blood (1985) 1.33
Procoagulant activity in bronchoalveolar lavage in the adult respiratory distress syndrome. Contribution of tissue factor associated with factor VII. Am Rev Respir Dis (1987) 1.31
Activated protein C stimulates the fibrinolytic activity of cultured endothelial cells and decreases antiactivator activity. Proc Natl Acad Sci U S A (1985) 1.27
ECAT angina pectoris study: baseline associations of haemostatic factors with extent of coronary arteriosclerosis and other coronary risk factors in 3000 patients with angina pectoris undergoing coronary angiography. Eur Heart J (1993) 0.88
Microvascular responses to sepsis: clinical significance. Pathophysiology (2002) 0.88
Long-term prognostic value of the hemorheological profile in transmural myocardial infarction survivors: 60-month clinical follow-up. Rev Port Cardiol (2002) 0.82
Low normal level of protein C or of antithrombin increases risk for recurrent cardiovascular events. Blood Coagul Fibrinolysis (2005) 0.82
Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network. N Engl J Med (2000) 48.03
Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008. Crit Care Med (2008) 31.57
Acute respiratory distress syndrome: the Berlin Definition. JAMA (2012) 21.04
Comparison of two fluid-management strategies in acute lung injury. N Engl J Med (2006) 19.54
Intensity of renal support in critically ill patients with acute kidney injury. N Engl J Med (2008) 14.40
2013 ACCF/AHA guideline for the management of heart failure: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol (2013) 11.88
Higher versus lower positive end-expiratory pressures in patients with the acute respiratory distress syndrome. N Engl J Med (2004) 11.78
2013 ACCF/AHA guideline for the management of heart failure: a report of the American College of Cardiology Foundation/American Heart Association Task Force on practice guidelines. Circulation (2013) 10.07
Efficacy and safety of corticosteroids for persistent acute respiratory distress syndrome. N Engl J Med (2006) 9.52
Drotrecogin alfa (activated) in adults with septic shock. N Engl J Med (2012) 9.19
Third universal definition of myocardial infarction. J Am Coll Cardiol (2012) 8.59
Third universal definition of myocardial infarction. Circulation (2012) 8.47
Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008. Intensive Care Med (2007) 8.33
Lebrikizumab treatment in adults with asthma. N Engl J Med (2011) 8.07
Third universal definition of myocardial infarction. Eur Heart J (2012) 7.98
Pulmonary-artery versus central venous catheter to guide treatment of acute lung injury. N Engl J Med (2006) 7.97
Pulmonary dead-space fraction as a risk factor for death in the acute respiratory distress syndrome. N Engl J Med (2002) 6.17
Lower tidal volume ventilation and plasma cytokine markers of inflammation in patients with acute lung injury. Crit Care Med (2005) 5.76
Intrapulmonary delivery of bone marrow-derived mesenchymal stem cells improves survival and attenuates endotoxin-induced acute lung injury in mice. J Immunol (2007) 5.66
Vitamin D therapy and cardiac structure and function in patients with chronic kidney disease: the PRIMO randomized controlled trial. JAMA (2012) 5.27
Randomized, placebo-controlled clinical trial of an aerosolized β₂-agonist for treatment of acute lung injury. Am J Respir Crit Care Med (2011) 5.24
Clinical predictors of and mortality in acute respiratory distress syndrome: potential role of red cell transfusion. Crit Care Med (2005) 5.16
Enteral omega-3 fatty acid, gamma-linolenic acid, and antioxidant supplementation in acute lung injury. JAMA (2011) 5.08
Fibroblast growth factor 23 and left ventricular hypertrophy in chronic kidney disease. Circulation (2009) 4.87
Initial trophic vs full enteral feeding in patients with acute lung injury: the EDEN randomized trial. JAMA (2012) 4.67
An official American Thoracic Society workshop report: features and measurements of experimental acute lung injury in animals. Am J Respir Cell Mol Biol (2011) 4.65
Design, conduct, analysis and reporting of a multi-national placebo-controlled trial of activated protein C for persistent septic shock. Intensive Care Med (2008) 4.21
N-terminal pro-B-type natriuretic peptide testing improves the management of patients with suspected acute heart failure: primary results of the Canadian prospective randomized multicenter IMPROVE-CHF study. Circulation (2007) 3.97
Partial thrombosis of the false lumen in patients with acute type B aortic dissection. N Engl J Med (2007) 3.92
An official American Thoracic Society public policy statement: Novel risk factors and the global burden of chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2010) 3.92
2013 ACCF/AHA guideline for the management of heart failure: executive summary: a report of the American College of Cardiology Foundation/American Heart Association Task Force on practice guidelines. Circulation (2013) 3.86
Recent trends in acute lung injury mortality: 1996-2005. Crit Care Med (2009) 3.86
Allogeneic human mesenchymal stem cells for treatment of E. coli endotoxin-induced acute lung injury in the ex vivo perfused human lung. Proc Natl Acad Sci U S A (2009) 3.84
Prevention of ventilator-associated pneumonia: an evidence-based systematic review. Ann Intern Med (2003) 3.74
Acute traumatic coagulopathy: initiated by hypoperfusion: modulated through the protein C pathway? Ann Surg (2007) 3.49
The role of open-lung biopsy in ARDS. Chest (2004) 3.46
Rosuvastatin for sepsis-associated acute respiratory distress syndrome. N Engl J Med (2014) 3.39
Receptor for advanced glycation end-products is a marker of type I cell injury in acute lung injury. Am J Respir Crit Care Med (2006) 3.38
Randomized clinical trial of activated protein C for the treatment of acute lung injury. Am J Respir Crit Care Med (2008) 3.28
Effect of prone positioning on clinical outcomes in children with acute lung injury: a randomized controlled trial. JAMA (2005) 3.21
The Berlin definition of ARDS: an expanded rationale, justification, and supplementary material. Intensive Care Med (2012) 3.18
Transfusion-related acute lung injury: incidence and risk factors. Blood (2011) 3.12
Platelet depletion and aspirin treatment protect mice in a two-event model of transfusion-related acute lung injury. J Clin Invest (2009) 3.08
Polymorphonuclear leukocytes mediate Staphylococcus aureus Panton-Valentine leukocidin-induced lung inflammation and injury. Proc Natl Acad Sci U S A (2010) 3.05
Nonventilatory treatments for acute lung injury and ARDS. Chest (2007) 3.02
Elevated levels of plasminogen activator inhibitor-1 in pulmonary edema fluid are associated with mortality in acute lung injury. Am J Physiol Lung Cell Mol Physiol (2003) 3.02
Postobstructive pulmonary edema: a case for hydrostatic mechanisms. Chest (2007) 2.97
Challenges in end-of-life care in the ICU: statement of the 5th International Consensus Conference in Critical Care: Brussels, Belgium, April 2003: executive summary. Crit Care Med (2004) 2.95
Cytokine-mediated inflammation in acute lung injury. Cytokine Growth Factor Rev (2003) 2.95
COPD and incident cardiovascular disease hospitalizations and mortality: Kaiser Permanente Medical Care Program. Chest (2005) 2.88
QTc prolongation, torsades de pointes, and psychotropic medications. Psychosomatics (2013) 2.80
Trauma-associated lung injury differs clinically and biologically from acute lung injury due to other clinical disorders. Crit Care Med (2007) 2.79
The adult respiratory distress syndrome cognitive outcomes study: long-term neuropsychological function in survivors of acute lung injury. Am J Respir Crit Care Med (2012) 2.72
Assessment of echocardiography and biomarkers for the extended prediction of cardiotoxicity in patients treated with anthracyclines, taxanes, and trastuzumab. Circ Cardiovasc Imaging (2012) 2.72
Antibacterial effect of human mesenchymal stem cells is mediated in part from secretion of the antimicrobial peptide LL-37. Stem Cells (2010) 2.72
Subglottic secretion drainage for preventing ventilator-associated pneumonia: a meta-analysis. Am J Med (2005) 2.67
Clinically relevant concentrations of beta2-adrenergic agonists stimulate maximal cyclic adenosine monophosphate-dependent airspace fluid clearance and decrease pulmonary edema in experimental acid-induced lung injury. Crit Care Med (2004) 2.66
Mesenchymal stem cells and idiopathic pulmonary fibrosis. Potential for clinical testing. Am J Respir Crit Care Med (2013) 2.66
Hyperoxia causes angiopoietin 2-mediated acute lung injury and necrotic cell death. Nat Med (2006) 2.63
Effects of recruitment maneuvers in patients with acute lung injury and acute respiratory distress syndrome ventilated with high positive end-expiratory pressure. Crit Care Med (2003) 2.63
Clinical practice. Acute pulmonary edema. N Engl J Med (2005) 2.62
Higher urine nitric oxide is associated with improved outcomes in patients with acute lung injury. Am J Respir Crit Care Med (2006) 2.61
Anemia and mortality in heart failure patients a systematic review and meta-analysis. J Am Coll Cardiol (2008) 2.59
Amino-terminal pro-brain natriuretic peptide for the diagnosis of acute heart failure in patients with previous obstructive airway disease. Ann Emerg Med (2006) 2.57
Long-term survival in patients presenting with type B acute aortic dissection: insights from the International Registry of Acute Aortic Dissection. Circulation (2006) 2.56
Transfusion-related acute lung injury: a review. Chest (2004) 2.56
Acute kidney injury in patients with acute lung injury: impact of fluid accumulation on classification of acute kidney injury and associated outcomes. Crit Care Med (2011) 2.55
Simvastatin decreases lipopolysaccharide-induced pulmonary inflammation in healthy volunteers. Am J Respir Crit Care Med (2009) 2.52
Pediatric acute lung injury: prospective evaluation of risk factors associated with mortality. Am J Respir Crit Care Med (2004) 2.51
Neutrophils and their Fc gamma receptors are essential in a mouse model of transfusion-related acute lung injury. J Clin Invest (2006) 2.50
Significance of von Willebrand factor in septic and nonseptic patients with acute lung injury. Am J Respir Crit Care Med (2004) 2.49
Pharmacotherapy of acute lung injury and the acute respiratory distress syndrome. J Intensive Care Med (2006) 2.47
Prolonged hypoxia differentially regulates hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha expression in lung epithelial cells: implication of natural antisense HIF-1alpha. J Biol Chem (2004) 2.42
Vitamin D reduces left atrial volume in patients with left ventricular hypertrophy and chronic kidney disease. Am Heart J (2012) 2.42
Concise review: Mesenchymal stem cells for acute lung injury: role of paracrine soluble factors. Stem Cells (2011) 2.41
Low tidal volume reduces epithelial and endothelial injury in acid-injured rat lungs. Am J Respir Crit Care Med (2002) 2.40
Myocardial injury and ventricular dysfunction related to training levels among nonelite participants in the Boston marathon. Circulation (2006) 2.40
Ligation of protease-activated receptor 1 enhances alpha(v)beta6 integrin-dependent TGF-beta activation and promotes acute lung injury. J Clin Invest (2006) 2.40
Active and passive cigarette smoking and acute lung injury after severe blunt trauma. Am J Respir Crit Care Med (2011) 2.39
A protocol for high-frequency oscillatory ventilation in adults: results from a roundtable discussion. Crit Care Med (2007) 2.38