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A human promyelocytic-like population is responsible for the immune suppression mediated by myeloid-derived suppressor cells.
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In vivo administration of artificial antigen-presenting cells activates low-avidity T cells for treatment of cancer.
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Preventive vaccination with telomerase controls tumor growth in genetically engineered and carcinogen-induced mouse models of cancer.
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Therapeutic effectiveness of recombinant cancer vaccines is associated with a prevalent T-cell receptor alpha usage by melanoma-specific CD8+ T lymphocytes.
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Differently immunogenic cancers in mice induce immature myeloid cells that suppress CTL in vitro but not in vivo following transfer.
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