Published in Neoplasia on December 01, 2012
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Similar MLL-associated leukemias arising from self-renewing stem cells and short-lived myeloid progenitors. Genes Dev (2003) 4.71
Genetic interaction of PGE2 and Wnt signaling regulates developmental specification of stem cells and regeneration. Cell (2009) 4.69
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The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in AML. Science (2010) 4.37
Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block. Nat Immunol (2006) 4.13
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Sox17 and Sox4 differentially regulate beta-catenin/T-cell factor activity and proliferation of colon carcinoma cells. Mol Cell Biol (2007) 2.67
Lineage regulators direct BMP and Wnt pathways to cell-specific programs during differentiation and regeneration. Cell (2011) 2.53
Homeodomain-mediated beta-catenin-dependent switching events dictate cell-lineage determination. Cell (2006) 2.40
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Kremen2 modulates Dickkopf2 activity during Wnt/LRP6 signaling. Gene (2003) 1.99
Enhanced SMYD3 expression is essential for the growth of breast cancer cells. Cancer Sci (2006) 1.90
A role for the Wnt gene family in hematopoiesis: expansion of multilineage progenitor cells. Blood (1997) 1.87
Cross-talk of WNT and FGF signaling pathways at GSK3beta to regulate beta-catenin and SNAIL signaling cascades. Cancer Biol Ther (2006) 1.68
Pygo2 expands mammary progenitor cells by facilitating histone H3 K4 methylation. J Cell Biol (2009) 1.65
Hedgehog signaling is dispensable for adult murine hematopoietic stem cell function and hematopoiesis. Cell Stem Cell (2009) 1.61
Hematopoietic stem cell expansion precedes the generation of committed myeloid leukemia-initiating cells in C/EBPalpha mutant AML. Cancer Cell (2009) 1.54
Negative regulation of the Wnt-beta-catenin pathway by the transcriptional repressor HBP1. EMBO J (2001) 1.45
Characterization of the Kremen-binding site on Dkk1 and elucidation of the role of Kremen in Dkk-mediated Wnt antagonism. J Biol Chem (2008) 1.35
Maternal and zygotic control of zebrafish dorsoventral axial patterning. Annu Rev Genet (2011) 1.30
Independent prognostic variables in acute myeloid leukaemia. Blood Rev (2010) 1.29
Dapper1 is a nucleocytoplasmic shuttling protein that negatively modulates Wnt signaling in the nucleus. J Biol Chem (2008) 1.26
Wnt signaling in hematopoiesis: crucial factors for self-renewal, proliferation, and cell fate decisions. J Cell Biochem (2010) 1.18
Activation of Wnt signaling in hematopoietic regeneration. Stem Cells (2008) 1.18
Targeting the WNT/beta-catenin/TCF/LEF1 axis in solid and haematological cancers: Multiplicity of therapeutic options. Eur J Cancer (2009) 1.12
Identification and mechanism of regulation of the zebrafish dorsal determinant. Proc Natl Acad Sci U S A (2011) 1.11
A role of Pygopus as an anti-repressor in facilitating Wnt-dependent transcription. Proc Natl Acad Sci U S A (2008) 1.11
The emerging role of Wnt signaling in the pathogenesis of acute myeloid leukemia. Leukemia (2007) 1.09
Proliferation and bone marrow engraftment of AML blasts is dependent on β-catenin signalling. Br J Haematol (2010) 1.01
Dkk1 stabilizes Wnt co-receptor LRP6: implication for Wnt ligand-induced LRP6 down-regulation. PLoS One (2010) 0.99
Wnt10b activates the Wnt, notch, and NFκB pathways in U2OS osteosarcoma cells. J Cell Biochem (2011) 0.96
Down-regulation of microRNAs 222/221 in acute myelogenous leukemia with deranged core-binding factor subunits. Neoplasia (2010) 0.93
High levels of the adhesion molecule CD44 on leukemic cells generate acute myeloid leukemia relapse after withdrawal of the initial transforming event. Leukemia (2010) 0.93
Depletion of Med10 enhances Wnt and suppresses Nodal signaling during zebrafish embryogenesis. Dev Biol (2006) 0.91
Linking hematopoietic regeneration to developmental signaling pathways: a story of BMP and Wnt. Cell Cycle (2012) 0.80
Secondary axis induction by heterospecific organizers in zebrafish. Dev Dyn (1996) 0.78
AC133 expression on acute myeloid leukemia blasts: correlation to FAB and to CD34 expression and possible implications for peripheral blood progenitor cell purging in AML. Leuk Res (2001) 0.78
Nodal/Bozozok-independent induction of the dorsal organizer by zebrafish cell lines. Dev Biol (2008) 0.77
Coordinated regulation of myeloid cells by tumours. Nat Rev Immunol (2012) 12.19
Hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia. N Engl J Med (2002) 8.86
New prognostic scoring system for primary myelofibrosis based on a study of the International Working Group for Myelofibrosis Research and Treatment. Blood (2008) 7.73
Multiplexed genotyping with sequence-tagged molecular inversion probes. Nat Biotechnol (2003) 7.02
Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on CD8+ T cells. J Clin Invest (2006) 6.61
Altered macrophage differentiation and immune dysfunction in tumor development. J Clin Invest (2007) 6.31
Myeloid suppressor cells in cancer: recruitment, phenotype, properties, and mechanisms of immune suppression. Semin Cancer Biol (2005) 6.05
Retinoic acid and arsenic trioxide for acute promyelocytic leukemia. N Engl J Med (2013) 5.72
Multipeptide immune response to cancer vaccine IMA901 after single-dose cyclophosphamide associates with longer patient survival. Nat Med (2012) 5.44
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The terminology issue for myeloid-derived suppressor cells. Cancer Res (2007) 4.37
Tumor-induced tolerance and immune suppression by myeloid derived suppressor cells. Immunol Rev (2008) 4.36
Phosphodiesterase-5 inhibition augments endogenous antitumor immunity by reducing myeloid-derived suppressor cell function. J Exp Med (2006) 4.20
Imatinib induces hematologic and cytogenetic responses in patients with chronic myelogenous leukemia in myeloid blast crisis: results of a phase II study. Blood (2002) 4.00
High-dose granulocyte-macrophage colony-stimulating factor-producing vaccines impair the immune response through the recruitment of myeloid suppressor cells. Cancer Res (2004) 3.94
Multigene amplification and massively parallel sequencing for cancer mutation discovery. Proc Natl Acad Sci U S A (2007) 3.93
Tumor-induced tolerance and immune suppression depend on the C/EBPbeta transcription factor. Immunity (2010) 3.88
Clinicopathological definition of Waldenstrom's macroglobulinemia: consensus panel recommendations from the Second International Workshop on Waldenstrom's Macroglobulinemia. Semin Oncol (2003) 3.88
Multiplex amplification enabled by selective circularization of large sets of genomic DNA fragments. Nucleic Acids Res (2005) 3.59
Myeloid suppressor lines inhibit T cell responses by an NO-dependent mechanism. J Immunol (2002) 3.56
Multicenter independent assessment of outcomes in chronic myeloid leukemia patients treated with imatinib. J Natl Cancer Inst (2011) 3.51
Life expectancy and prognostic factors for survival in patients with polycythemia vera and essential thrombocythemia. Am J Med (2004) 3.26
Hierarchy of immunosuppressive strength among myeloid-derived suppressor cell subsets is determined by GM-CSF. Eur J Immunol (2010) 3.18
Cardiovascular disease and diabetes in the Northern Sweden Health and Disease Study Cohort - evaluation of risk factors and their interactions. Scand J Public Health Suppl (2003) 2.72
Derangement of immune responses by myeloid suppressor cells. Cancer Immunol Immunother (2003) 2.65
IL4Ralpha+ myeloid-derived suppressor cell expansion in cancer patients. J Immunol (2009) 2.64
PD-L1 is a novel direct target of HIF-1α, and its blockade under hypoxia enhanced MDSC-mediated T cell activation. J Exp Med (2014) 2.51
Nitroaspirin corrects immune dysfunction in tumor-bearing hosts and promotes tumor eradication by cancer vaccination. Proc Natl Acad Sci U S A (2005) 2.49
In situ genotyping individual DNA molecules by target-primed rolling-circle amplification of padlock probes. Nat Methods (2004) 2.40
Duplication of FGF3, FGF4, FGF19 and ORAOV1 causes hair ridge and predisposition to dermoid sinus in Ridgeback dogs. Nat Genet (2007) 2.33
Long-term outcomes of 107 patients with myelofibrosis receiving JAK1/JAK2 inhibitor ruxolitinib: survival advantage in comparison to matched historical controls. Blood (2012) 2.32
In situ detection and genotyping of individual mRNA molecules. Nat Methods (2010) 2.29
In situ sequencing for RNA analysis in preserved tissue and cells. Nat Methods (2013) 2.13
Chemokine nitration prevents intratumoral infiltration of antigen-specific T cells. J Exp Med (2011) 2.06
A human promyelocytic-like population is responsible for the immune suppression mediated by myeloid-derived suppressor cells. Blood (2011) 2.03
Evidence- and consensus-based practice guidelines for the therapy of primary myelodysplastic syndromes. A statement from the Italian Society of Hematology. Haematologica (2002) 1.91
Update on treatment recommendations from the Fourth International Workshop on Waldenstrom's Macroglobulinemia. J Clin Oncol (2008) 1.89
Impact of ruxolitinib on the natural history of primary myelofibrosis: a comparison of the DIPSS and the COMFORT-2 cohorts. Blood (2014) 1.87
Prognostic impact of c-KIT mutations in core binding factor leukemias: an Italian retrospective study. Blood (2005) 1.87
Myeloid-derived suppressor cells in cancer patients: a clinical perspective. J Immunother (2012) 1.87
Prognostic factors for malignant transformation in monoclonal gammopathy of undetermined significance and smoldering multiple myeloma. J Clin Oncol (2002) 1.76
Myeloid-derived suppressor cell heterogeneity in human cancers. Ann N Y Acad Sci (2014) 1.69
Therapeutic targeting of myeloid-derived suppressor cells. Curr Opin Pharmacol (2009) 1.68
Digital quantification using amplified single-molecule detection. Nat Methods (2006) 1.66
Control of immune response by amino acid metabolism. Immunol Rev (2010) 1.63
Targeted enrichment of genomic DNA regions for next-generation sequencing. Brief Funct Genomics (2011) 1.63
Anatomically restricted synergistic antiviral activities of innate and adaptive immune cells in the skin. Cell Host Microbe (2013) 1.62
Part I: Vaccines for solid tumours. Lancet Oncol (2004) 1.61
Sox18 and Sox7 play redundant roles in vascular development. Blood (2007) 1.60
Circle-to-circle amplification for precise and sensitive DNA analysis. Proc Natl Acad Sci U S A (2004) 1.59
Immune tolerance to tumor antigens occurs in a specialized environment of the spleen. Cell Rep (2012) 1.59
Countrywide estimates of forest variables using satellite data and field data from the National Forest Inventory. Ambio (2003) 1.57
Toward the identification of a tolerogenic signature in IDO-competent dendritic cells. Blood (2005) 1.56
Nitric oxide, a double edged sword in cancer biology: searching for therapeutic opportunities. Med Res Rev (2007) 1.55
Update on treatment recommendations from the Third International Workshop on Waldenstrom's macroglobulinemia. Blood (2006) 1.51
Consensus conference on the management of tumor lysis syndrome. Haematologica (2008) 1.49
Parallel gene analysis with allele-specific padlock probes and tag microarrays. Nucleic Acids Res (2003) 1.48
Modulation of microRNA expression in human T-cell development: targeting of NOTCH3 by miR-150. Blood (2011) 1.47
Plerixafor and G-CSF for PBSC mobilization in patients with lymphoma who failed previous attempts with G-CSF and chemotherapy: a REL (Rete Ematologica Lombarda) experience. Leuk Res (2011) 1.47
PieceMaker: selection of DNA fragments for selector-guided multiplex amplification. Nucleic Acids Res (2005) 1.46
Update on recommendations for assessing response from the Third International Workshop on Waldenstrom's Macroglobulinemia. Clin Lymphoma Myeloma (2006) 1.44
Prognostic value of circulating CD34+ cells in myelodysplastic syndromes. Leuk Res (2008) 1.42
C/EBP beta gene inactivation causes both impaired and enhanced gene expression and inverse regulation of IL-12 p40 and p35 mRNAs in macrophages. J Immunol (2002) 1.41
Splenic marginal zone lymphoma: a prognostic model for clinical use. Blood (2006) 1.38
Targeted resequencing of candidate genes using selector probes. Nucleic Acids Res (2010) 1.37
Adipose tissue dominates chronic arm lymphedema following breast cancer: an analysis using volume rendered CT images. Lymphat Res Biol (2006) 1.33
Role of arginine metabolism in immunity and immunopathology. Immunobiology (2007) 1.33
Prognostic validation of the international classification of immunoglobulin M gammopathies: a survival advantage for patients with immunoglobulin M monoclonal gammopathy of undetermined significance? Clin Cancer Res (2005) 1.32
Myeloid-derived suppressor cell role in tumor-related inflammation. Cancer Lett (2008) 1.31
Alemtuzumab as consolidation after a response to fludarabine is effective in purging residual disease in patients with chronic lymphocytic leukemia. J Clin Oncol (2006) 1.30
A genomic and proteomic study of the spectrum of nonalcoholic fatty liver disease. Hepatology (2005) 1.29
KIT activating mutations: incidence in adult and pediatric acute myeloid leukemia, and identification of an internal tandem duplication. Haematologica (2004) 1.29
Cancer immunotherapy based on killing of Salmonella-infected tumor cells. Cancer Res (2005) 1.28
Transcription factors in myeloid-derived suppressor cell recruitment and function. Curr Opin Immunol (2011) 1.25
Nitrous oxide production in a forest soil at low temperatures - processes and environmental controls. FEMS Microbiol Ecol (2004) 1.23
ProbeMaker: an extensible framework for design of sets of oligonucleotide probes. BMC Bioinformatics (2005) 1.23
Dynamic International Prognostic Scoring System (DIPSS) predicts progression to acute myeloid leukemia in primary myelofibrosis. Blood (2010) 1.23
Organic material: the primary control on mercury methylation and ambient methyl mercury concentrations in estuarine sediments. Environ Sci Technol (2006) 1.22
A dual-tag microarray platform for high-performance nucleic acid and protein analyses. Nucleic Acids Res (2008) 1.20
Autoimmune B-cell lymphopenia after successful adoptive therapy with telomerase-specific T lymphocytes. Blood (2009) 1.20
Improving survival trends in primary myelofibrosis: an international study. J Clin Oncol (2012) 1.19
Effect of monitors on approximal caries detection in digital radiographs--standard versus precalibrated DICOM part 14 displays: an in vitro study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2009) 1.18
The effects of forestry on Hg bioaccumulation in nemoral/boreal waters and recommendations for good silvicultural practice. Ambio (2009) 1.18
Selection of dental materials and longevity of replaced restorations in Public Dental Health clinics in northern Sweden. J Dent (2009) 1.16
Remote origins of tail-anchored proteins. Traffic (2010) 1.16
Chronic lymphocytic leukemia: novel prognostic factors and their relevance for risk-adapted therapeutic strategies. Haematologica (2005) 1.15
TWEAK is a positive regulator of cardiomyocyte proliferation. Cardiovasc Res (2009) 1.15
Response assessment in Waldenström macroglobulinaemia: update from the VIth International Workshop. Br J Haematol (2012) 1.14
Microarray-based molecular detection of foot-and-mouth disease, vesicular stomatitis and swine vesicular disease viruses, using padlock probes. J Virol Methods (2007) 1.14
Hepatic gene expression in patients with obesity-related non-alcoholic steatohepatitis. Liver Int (2005) 1.13
A dynamic prognostic model to predict survival in post-polycythemia vera myelofibrosis. Blood (2008) 1.13
Lateral-flow and up-converting phosphor reporters to detect single-stranded nucleic acids in a sandwich-hybridization assay. Anal Biochem (2003) 1.12
DNA repair genes are selectively mutated in diffuse large B cell lymphomas. J Exp Med (2013) 1.12