Published in Dev Cell on November 01, 2004
Wnt/beta-catenin signaling directs multiple stages of tooth morphogenesis. Dev Biol (2007) 2.26
Inactivation of a novel FGF23 regulator, FAM20C, leads to hypophosphatemic rickets in mice. PLoS Genet (2012) 2.19
An integrated gene regulatory network controls stem cell proliferation in teeth. PLoS Biol (2007) 2.03
An FGF signaling loop sustains the generation of differentiated progeny from stem cells in mouse incisors. Development (2007) 1.95
Amelogenesis imperfecta. Orphanet J Rare Dis (2007) 1.85
Sox2+ stem cells contribute to all epithelial lineages of the tooth via Sfrp5+ progenitors. Dev Cell (2012) 1.57
Hedgehog signaling regulates the generation of ameloblast progenitors in the continuously growing mouse incisor. Development (2010) 1.55
The odontode explosion: the origin of tooth-like structures in vertebrates. Bioessays (2010) 1.38
Morphoregulation of teeth: modulating the number, size, shape and differentiation by tuning Bmp activity. Evol Dev (2005) 1.38
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Common developmental pathways link tooth shape to regeneration. Dev Biol (2013) 1.10
Conditional activin receptor type 1B (Acvr1b) knockout mice reveal hair loss abnormality. J Invest Dermatol (2010) 1.09
Molecular genetics of ameloblast cell lineage. J Exp Zool B Mol Dev Evol (2009) 1.08
The Pitx2:miR-200c/141:noggin pathway regulates Bmp signaling and ameloblast differentiation. Development (2013) 1.04
Enamel-free teeth: Tbx1 deletion affects amelogenesis in rodent incisors. Dev Biol (2009) 1.03
Inactivation of Tgfbr2 in Osterix-Cre expressing dental mesenchyme disrupts molar root formation. Dev Biol (2013) 0.93
Expression of microRNAs in the stem cell niche of the adult mouse incisor. PLoS One (2011) 0.92
Unique and shared gene expression patterns in Atlantic salmon (Salmo salar) tooth development. Dev Genes Evol (2008) 0.92
Ctip2/Bcl11b controls ameloblast formation during mammalian odontogenesis. Proc Natl Acad Sci U S A (2009) 0.92
From molecules to mastication: the development and evolution of teeth. Wiley Interdiscip Rev Dev Biol (2012) 0.92
Postnatal epithelium and mesenchyme stem/progenitor cells in bioengineered amelogenesis and dentinogenesis. Biomaterials (2013) 0.89
Odontogenic keratocysts arise from quiescent epithelial rests and are associated with deregulated hedgehog signaling in mice and humans. Am J Pathol (2006) 0.88
FGFR2 in the dental epithelium is essential for development and maintenance of the maxillary cervical loop, a stem cell niche in mouse incisors. Dev Dyn (2009) 0.87
Characterization of progenitor cells in pulps of murine incisors. J Dent Res (2010) 0.86
Cessation of epithelial Bmp signaling switches the differentiation of crown epithelia to the root lineage in a β-catenin-dependent manner. Mol Cell Biol (2013) 0.85
A role for suppressed incisor cuspal morphogenesis in the evolution of mammalian heterodont dentition. Proc Natl Acad Sci U S A (2009) 0.84
Dynamic expression of Six family genes in the dental mesenchyme and the epithelial ameloblast stem/progenitor cells during murine tooth development. J Anat (2009) 0.84
BCL11B regulates epithelial proliferation and asymmetric development of the mouse mandibular incisor. PLoS One (2012) 0.83
Coevolutionary patterning of teeth and taste buds. Proc Natl Acad Sci U S A (2015) 0.83
Cell cycle control, DNA damage repair, and apoptosis-related pathways control pre-ameloblasts differentiation during tooth development. BMC Genomics (2015) 0.82
Alk5-mediated transforming growth factor β signaling acts upstream of fibroblast growth factor 10 to regulate the proliferation and maintenance of dental epithelial stem cells. Mol Cell Biol (2011) 0.82
The LIM homeodomain transcription factor LHX6: a transcriptional repressor that interacts with pituitary homeobox 2 (PITX2) to regulate odontogenesis. J Biol Chem (2012) 0.81
p38α MAPK is required for tooth morphogenesis and enamel secretion. J Biol Chem (2014) 0.80
A New Approach to Feedback for Robust Signaling Gradients. Stud Appl Math (2014) 0.80
Sox2 and Lef-1 interact with Pitx2 to regulate incisor development and stem cell renewal. Development (2016) 0.80
On the cutting edge of organ renewal: Identification, regulation, and evolution of incisor stem cells. Genesis (2013) 0.79
microRNA miR-34a regulates cytodifferentiation and targets multi-signaling pathways in human dental papilla cells. PLoS One (2012) 0.79
Wnt/β-Catenin Regulates the Activity of Epiprofin/Sp6, SHH, FGF, and BMP to Coordinate the Stages of Odontogenesis. Front Cell Dev Biol (2016) 0.78
An Evo-Devo perspective on ever-growing teeth in mammals and dental stem cell maintenance. Front Physiol (2014) 0.77
Conditional Knockout in Mice Reveals the Critical Roles of Ppp2ca in Epidermis Development. Int J Mol Sci (2016) 0.76
Overexpression of follistatin in the mouse epididymis disrupts fluid resorption and sperm transit in testicular excurrent ducts. Biol Reprod (2012) 0.75
Common mechanisms in development and disease: BMP signaling in craniofacial development. Cytokine Growth Factor Rev (2015) 0.75
Progress in Bioengineered Whole Tooth Research: From Bench to Dental Patient Chair. Curr Oral Health Rep (2016) 0.75
De novo genome and transcriptome assembly of the Canadian beaver (Castor canadensis). G3 (Bethesda) (2017) 0.75
Transgenic overexpression of gremlin results in developmental defects in enamel and dentin in mice. Connect Tissue Res (2008) 0.75
Mutant GDF5 enhances ameloblast differentiation via accelerated BMP2-induced Smad1/5/8 phosphorylation. Sci Rep (2016) 0.75
Test Tube Tooth: The Next Big Thing. J Clin Diagn Res (2016) 0.75
Irx1 regulates dental outer enamel epithelial and lung alveolar type II epithelial differentiation. Dev Biol (2017) 0.75
Wound repair and regeneration. Nature (2008) 12.30
Active caspase-1 is a regulator of unconventional protein secretion. Cell (2008) 5.89
Cancer as an overhealing wound: an old hypothesis revisited. Nat Rev Mol Cell Biol (2008) 4.05
Mutations in AXIN2 cause familial tooth agenesis and predispose to colorectal cancer. Am J Hum Genet (2004) 3.21
Genetic analysis of the mammalian transforming growth factor-beta superfamily. Endocr Rev (2002) 3.06
Pervasive social deficits, but normal parturition, in oxytocin receptor-deficient mice. Proc Natl Acad Sci U S A (2005) 2.84
NOBOX deficiency disrupts early folliculogenesis and oocyte-specific gene expression. Science (2004) 2.77
Disruption of Fgf10/Fgfr2b-coordinated epithelial-mesenchymal interactions causes cleft palate. J Clin Invest (2004) 2.72
The inflammasome mediates UVB-induced activation and secretion of interleukin-1beta by keratinocytes. Curr Biol (2007) 2.57
Mechanisms of ectodermal organogenesis. Dev Biol (2003) 2.55
The mammalian ovary from genesis to revelation. Endocr Rev (2009) 2.31
Continuous tooth generation in mouse is induced by activated epithelial Wnt/beta-catenin signaling. Proc Natl Acad Sci U S A (2006) 2.25
p63 regulates multiple signalling pathways required for ectodermal organogenesis and differentiation. Development (2006) 2.23
Nonindependence of mammalian dental characters. Nature (2004) 2.19
Molecular profiling uncovers a p53-associated role for microRNA-31 in inhibiting the proliferation of serous ovarian carcinomas and other cancers. Cancer Res (2010) 2.16
A bioinformatics tool for linking gene expression profiling results with public databases of microRNA target predictions. RNA (2008) 2.16
Zygote arrest 1 (Zar1) is a novel maternal-effect gene critical for the oocyte-to-embryo transition. Nat Genet (2003) 2.09
Regulation of mammalian tooth cusp patterning by ectodin. Science (2005) 2.05
GDF11 controls the timing of progenitor cell competence in developing retina. Science (2005) 2.04
Mutant mice lacking acetyl-CoA carboxylase 1 are embryonically lethal. Proc Natl Acad Sci U S A (2005) 2.04
A crucial role of beta 1 integrins for keratinocyte migration in vitro and during cutaneous wound repair. Development (2002) 2.04
The importance of signal pathway modulation in all aspects of tooth development. J Exp Zool B Mol Dev Evol (2009) 2.03
An integrated gene regulatory network controls stem cell proliferation in teeth. PLoS Biol (2007) 2.03
High-grade serous ovarian cancer arises from fallopian tube in a mouse model. Proc Natl Acad Sci U S A (2012) 2.03
TEX14 is essential for intercellular bridges and fertility in male mice. Proc Natl Acad Sci U S A (2006) 2.01
c-Met is essential for wound healing in the skin. J Cell Biol (2007) 1.98
Nrf2 transcription factor, a novel target of keratinocyte growth factor action which regulates gene expression and inflammation in the healing skin wound. Mol Cell Biol (2002) 1.97
Follistatin operates downstream of Wnt4 in mammalian ovary organogenesis. Dev Dyn (2004) 1.96
A link between mir-100 and FRAP1/mTOR in clear cell ovarian cancer. Mol Endocrinol (2010) 1.94
Deletion of Dicer in somatic cells of the female reproductive tract causes sterility. Mol Endocrinol (2008) 1.91
Potentiation of fibroblast growth factor activity by synthetic heparin oligosaccharide glycodendrimers. Chem Biol (2007) 1.89
Stimulation of ectodermal organ development by Ectodysplasin-A1. Dev Biol (2003) 1.88
Oogenesis requires germ cell-specific transcriptional regulators Sohlh1 and Lhx8. Proc Natl Acad Sci U S A (2006) 1.87
Sclerostin is a novel secreted osteoclast-derived bone morphogenetic protein antagonist with unique ligand specificity. J Biol Chem (2003) 1.86
The three mouse actin-depolymerizing factor/cofilins evolved to fulfill cell-type-specific requirements for actin dynamics. Mol Biol Cell (2002) 1.85
GASZ is essential for male meiosis and suppression of retrotransposon expression in the male germline. PLoS Genet (2009) 1.83
Oxidative stress in normal and impaired wound repair. Pharmacol Res (2008) 1.80
Regulation of muscle mass by follistatin and activins. Mol Endocrinol (2010) 1.79
Roles of NPM2 in chromatin and nucleolar organization in oocytes and embryos. Science (2003) 1.78
Knockout of pentraxin 3, a downstream target of growth differentiation factor-9, causes female subfertility. Mol Endocrinol (2002) 1.77
Impaired liver regeneration in Nrf2 knockout mice: role of ROS-mediated insulin/IGF-1 resistance. EMBO J (2007) 1.76
Activating mutations of the tyrosine kinase receptor FGFR3 are associated with benign skin tumors in mice and humans. Hum Mol Genet (2005) 1.74
Activated Nrf2 impairs liver regeneration in mice by activation of genes involved in cell-cycle control and apoptosis. Hepatology (2014) 1.73
Targeted disruption of luteinizing hormone beta-subunit leads to hypogonadism, defects in gonadal steroidogenesis, and infertility. Proc Natl Acad Sci U S A (2004) 1.73
Conditional deletion of Smad1 and Smad5 in somatic cells of male and female gonads leads to metastatic tumor development in mice. Mol Cell Biol (2007) 1.72
Absence of the DNA-/RNA-binding protein MSY2 results in male and female infertility. Proc Natl Acad Sci U S A (2005) 1.71
MRP8 and MRP14 control microtubule reorganization during transendothelial migration of phagocytes. Blood (2004) 1.71
Oocyte regulation of metabolic cooperativity between mouse cumulus cells and oocytes: BMP15 and GDF9 control cholesterol biosynthesis in cumulus cells. Development (2007) 1.70
Regulation of hair follicle development by the TNF signal ectodysplasin and its receptor Edar. Development (2002) 1.70
Attenuation of allergic contact dermatitis through the endocannabinoid system. Science (2007) 1.70
Root or crown: a developmental choice orchestrated by the differential regulation of the epithelial stem cell niche in the tooth of two rodent species. Development (2003) 1.70
BMPR2 is required for postimplantation uterine function and pregnancy maintenance. J Clin Invest (2013) 1.70
MLL2 is required in oocytes for bulk histone 3 lysine 4 trimethylation and transcriptional silencing. PLoS Biol (2010) 1.68
Stable expression and characterization of N-terminal tagged recombinant human bone morphogenetic protein 15. Mol Hum Reprod (2009) 1.67
Mouse let-7 miRNA populations exhibit RNA editing that is constrained in the 5'-seed/ cleavage/anchor regions and stabilize predicted mmu-let-7a:mRNA duplexes. Genome Res (2008) 1.66
Tooth shape formation and tooth renewal: evolving with the same signals. Development (2012) 1.64
Granulosa cell-specific inactivation of follistatin causes female fertility defects. Mol Endocrinol (2003) 1.62
An important role of lymphatic vessel activation in limiting acute inflammation. Blood (2011) 1.62
Identification of a secreted BMP antagonist, ectodin, integrating BMP, FGF, and SHH signals from the tooth enamel knot. Dev Biol (2003) 1.58
Synergistic roles of BMP15 and GDF9 in the development and function of the oocyte-cumulus cell complex in mice: genetic evidence for an oocyte-granulosa cell regulatory loop. Dev Biol (2004) 1.58
Psoriasiform dermatitis is driven by IL-36-mediated DC-keratinocyte crosstalk. J Clin Invest (2012) 1.58
Sox2+ stem cells contribute to all epithelial lineages of the tooth via Sfrp5+ progenitors. Dev Cell (2012) 1.57
Ectodysplasin has a dual role in ectodermal organogenesis: inhibition of Bmp activity and induction of Shh expression. Development (2007) 1.53
Ectodysplasin A1 promotes placodal cell fate during early morphogenesis of ectodermal appendages. Development (2004) 1.53
Nobox is a homeobox-encoding gene preferentially expressed in primordial and growing oocytes. Mech Dev (2002) 1.52
Oocyte-derived BMP15 and FGFs cooperate to promote glycolysis in cumulus cells. Development (2007) 1.50
Ectodysplasin signaling in development. Cytokine Growth Factor Rev (2003) 1.48
Beyond wavy hairs: the epidermal growth factor receptor and its ligands in skin biology and pathology. Am J Pathol (2008) 1.47
The role of fibroblast growth factor receptor 2b in skin homeostasis and cancer development. EMBO J (2007) 1.45
ADAMTS1 proteinase is up-regulated in wounded skin and regulates migration of fibroblasts and endothelial cells. J Biol Chem (2005) 1.45
Nrf transcription factors in keratinocytes are essential for skin tumor prevention but not for wound healing. Mol Cell Biol (2006) 1.45
Transcriptional control of wound repair. Annu Rev Cell Dev Biol (2007) 1.44
Wound-healing studies in transgenic and knockout mice. Mol Biotechnol (2004) 1.43
Growth differentiation factor 9:bone morphogenetic protein 15 heterodimers are potent regulators of ovarian functions. Proc Natl Acad Sci U S A (2013) 1.42
The Vg1-related protein Gdf3 acts in a Nodal signaling pathway in the pre-gastrulation mouse embryo. Development (2006) 1.40
As the world grows: contraception in the 21st century. J Clin Invest (2008) 1.37
Sumo-1 function is dispensable in normal mouse development. Mol Cell Biol (2008) 1.37
Functional microRNA involved in endometriosis. Mol Endocrinol (2011) 1.36
Conversion of midbodies into germ cell intercellular bridges. Dev Biol (2007) 1.36
Nrf2 links epidermal barrier function with antioxidant defense. EMBO Mol Med (2012) 1.35
MRG15 regulates embryonic development and cell proliferation. Mol Cell Biol (2005) 1.35
Aldara activates TLR7-independent immune defence. Nat Commun (2013) 1.34
Premature luteinization and cumulus cell defects in ovarian-specific Smad4 knockout mice. Mol Endocrinol (2006) 1.33
Runx2 mediates FGF signaling from epithelium to mesenchyme during tooth morphogenesis. Dev Biol (2004) 1.32
A missense mutation in PAX9 in a family with distinct phenotype of oligodontia. Eur J Hum Genet (2003) 1.32
Loss of zona pellucida binding proteins in the acrosomal matrix disrupts acrosome biogenesis and sperm morphogenesis. Mol Cell Biol (2007) 1.31
Targeted expression of a dominant-negative fibroblast growth factor (FGF) receptor in gonadotropin-releasing hormone (GnRH) neurons reduces FGF responsiveness and the size of GnRH neuronal population. Mol Endocrinol (2004) 1.30
HILS1 is a spermatid-specific linker histone H1-like protein implicated in chromatin remodeling during mammalian spermiogenesis. Proc Natl Acad Sci U S A (2003) 1.28
Major chromatin remodeling in the germinal vesicle (GV) of mammalian oocytes is dispensable for global transcriptional silencing but required for centromeric heterochromatin function. Dev Biol (2004) 1.28
The Nrf2 transcription factor protects from toxin-induced liver injury and fibrosis. Lab Invest (2008) 1.27
Sustained epithelial beta-catenin activity induces precocious hair development but disrupts hair follicle down-growth and hair shaft formation. Development (2008) 1.27
Identification of Gasz, an evolutionarily conserved gene expressed exclusively in germ cells and encoding a protein with four ankyrin repeats, a sterile-alpha motif, and a basic leucine zipper. Mol Endocrinol (2002) 1.27
Intraovarian activins are required for female fertility. Mol Endocrinol (2007) 1.26
Discovery of novel microRNAs in female reproductive tract using next generation sequencing. PLoS One (2010) 1.26
Altered excitation-contraction coupling with skeletal muscle specific FKBP12 deficiency. FASEB J (2004) 1.24
Haploinsufficiency of kelch-like protein homolog 10 causes infertility in male mice. Proc Natl Acad Sci U S A (2004) 1.24
Progression of calvarial bone development requires Foxc1 regulation of Msx2 and Alx4. Dev Biol (2003) 1.23