Published in Development on May 01, 2002
Two adjacent trimeric Fas ligands are required for Fas signaling and formation of a death-inducing signaling complex. Mol Cell Biol (2003) 2.50
Reciprocal requirements for EDA/EDAR/NF-kappaB and Wnt/beta-catenin signaling pathways in hair follicle induction. Dev Cell (2009) 2.17
FGF4, a direct target of LEF1 and Wnt signaling, can rescue the arrest of tooth organogenesis in Lef1(-/-) mice. Genes Dev (2002) 1.88
Adenomatous polyposis coli (APC) is required for normal development of skin and thymus. PLoS Genet (2006) 1.86
Morpho-regulation of ectodermal organs: integument pathology and phenotypic variations in K14-Noggin engineered mice through modulation of bone morphogenic protein pathway. Am J Pathol (2004) 1.72
Generation of the primary hair follicle pattern. Proc Natl Acad Sci U S A (2006) 1.72
'Cyclic alopecia' in Msx2 mutants: defects in hair cycling and hair shaft differentiation. Development (2003) 1.70
An ancient gene network is co-opted for teeth on old and new jaws. PLoS Biol (2009) 1.60
Analysis of the temporal requirement for eda in hair and sweat gland development. J Invest Dermatol (2008) 1.55
A periodic pattern generator for dental diversity. BMC Biol (2008) 1.47
Mesenchymal-epithelial interactions during hair follicle morphogenesis and cycling. Semin Cell Dev Biol (2012) 1.41
The transcription factors c-rel and RelA control epidermal development and homeostasis in embryonic and adult skin via distinct mechanisms. Mol Cell Biol (2004) 1.39
EDA signaling and skin appendage development. Cell Cycle (2006) 1.39
Hairy tale of signaling in hair follicle development and cycling. Semin Cell Dev Biol (2012) 1.22
The interfollicular epidermis of adult mouse tail comprises two distinct cell lineages that are differentially regulated by Wnt, Edaradd, and Lrig1. Stem Cell Reports (2013) 1.20
Keratinocyte-specific ablation of the NF-κB regulatory protein A20 (TNFAIP3) reveals a role in the control of epidermal homeostasis. Cell Death Differ (2011) 1.13
Epidermal Wnt controls hair follicle induction by orchestrating dynamic signaling crosstalk between the epidermis and dermis. J Invest Dermatol (2012) 1.13
Generation and behavioral characterization of beta-catenin forebrain-specific conditional knock-out mice. Behav Brain Res (2008) 1.10
Fgf20 governs formation of primary and secondary dermal condensations in developing hair follicles. Genes Dev (2013) 1.10
A new scenario for the evolutionary origin of hair, feather, and avian scales. J Anat (2009) 1.08
A recurrent regulatory change underlying altered expression and Wnt response of the stickleback armor plates gene EDA. Elife (2015) 1.07
Ectodysplasin regulates the lymphotoxin-beta pathway for hair differentiation. Proc Natl Acad Sci U S A (2006) 1.04
The Edar subfamily in feather placode formation. Dev Biol (2007) 1.04
KGF and EGF signalling block hair follicle induction and promote interfollicular epidermal fate in developing mouse skin. Development (2009) 1.03
Dkk4 and Eda regulate distinctive developmental mechanisms for subtypes of mouse hair. PLoS One (2010) 1.01
X-linked anhidrotic ectodermal dysplasia disruption yields a mouse model for ocular surface disease and resultant blindness. Am J Pathol (2005) 0.99
Sweat gland progenitors in development, homeostasis, and wound repair. Cold Spring Harb Perspect Med (2014) 0.97
Signaling involved in hair follicle morphogenesis and development. Int J Mol Sci (2014) 0.97
Epidermal patterning and induction of different hair types during mouse embryonic development. Birth Defects Res C Embryo Today (2009) 0.95
An Integrated Transcriptome Atlas of Embryonic Hair Follicle Progenitors, Their Niche, and the Developing Skin. Dev Cell (2015) 0.92
Visualization and quantification of mouse prostate development by in situ hybridization. Differentiation (2012) 0.89
Three dimensional dental epithelial-mesenchymal constructs of predetermined size and shape for tooth regeneration. Biomaterials (2010) 0.89
Molecular basis of hypohidrotic ectodermal dysplasia: an update. J Appl Genet (2015) 0.88
Parallel developmental genetic features underlie stickleback gill raker evolution. Evodevo (2014) 0.87
Ectodysplasin regulates activator-inhibitor balance in murine tooth development through Fgf20 signaling. Development (2012) 0.85
The dermal papilla: an instructive niche for epithelial stem and progenitor cells in development and regeneration of the hair follicle. Cold Spring Harb Perspect Med (2014) 0.84
The death domain-containing protein Unc5CL is a novel MyD88-independent activator of the pro-inflammatory IRAK signaling cascade. Cell Death Differ (2011) 0.83
Correlating interleukin-12 stimulated interferon-γ production and the absence of ectodermal dysplasia and anhidrosis (EDA) in patients with mutations in NF-κB essential modulator (NEMO). J Clin Immunol (2014) 0.82
EDAR-induced hypohidrotic ectodermal dysplasia: a clinical study on signs and symptoms in individuals with a heterozygous c.1072C > T mutation. BMC Med Genet (2014) 0.82
Shh is required for Tabby hair follicle development. Cell Cycle (2011) 0.80
Identification of signaling pathways in early mammary gland development by mouse genetics. Breast Cancer Res (2004) 0.80
Defective lymphoid organogenesis underlies the immune deficiency caused by a heterozygous S32I mutation in IκBα. J Exp Med (2015) 0.79
The role of tumor necrosis factor receptor superfamily members in mammalian brain development, function and homeostasis. Rev Neurosci (2011) 0.79
Neural crest stem cell-specific deletion of the Pygopus2 gene modulates hair follicle development. Stem Cell Rev (2014) 0.79
Hair shaft structures in EDAR induced ectodermal dysplasia. BMC Med Genet (2015) 0.78
Ectodysplasin/NF-κB Promotes Mammary Cell Fate via Wnt/β-catenin Pathway. PLoS Genet (2015) 0.78
Embryonic attenuated Wnt/β-catenin signaling defines niche location and long-term stem cell fate in hair follicle. Elife (2015) 0.77
The anatomical placode in reptile scale morphogenesis indicates shared ancestry among skin appendages in amniotes. Sci Adv (2016) 0.76
Hair follicle morphogenesis and epidermal homeostasis in we/we wal/wal mice with postnatal alopecia. Histochem Cell Biol (2014) 0.76
A Cascade of Wnt, Eda, and Shh Signaling Is Essential for Touch Dome Merkel Cell Development. PLoS Genet (2016) 0.75
Ectodysplasin A promotes corneal epithelial cell proliferation. J Biol Chem (2017) 0.75
Anti-EDAR Agonist Antibody Therapy Resolves Palate Defects in Pax9(-/-) Mice. J Dent Res (2017) 0.75
SATB2 is a multifunctional determinant of craniofacial patterning and osteoblast differentiation. Cell (2006) 4.01
Age-specific evaluation of primary human papillomavirus screening vs conventional cytology in a randomized setting. J Natl Cancer Inst (2009) 3.71
Satb2 regulates callosal projection neuron identity in the developing cerebral cortex. Neuron (2008) 3.62
Mutations in AXIN2 cause familial tooth agenesis and predispose to colorectal cancer. Am J Hum Genet (2004) 3.21
Dynamics and interplay of nuclear architecture, genome organization, and gene expression. Genes Dev (2007) 2.95
Disruption of Fgf10/Fgfr2b-coordinated epithelial-mesenchymal interactions causes cleft palate. J Clin Invest (2004) 2.72
Mechanisms of ectodermal organogenesis. Dev Biol (2003) 2.55
Assembling a gene regulatory network for specification of the B cell fate. Dev Cell (2004) 2.46
Homeodomain-mediated beta-catenin-dependent switching events dictate cell-lineage determination. Cell (2006) 2.40
Evidence for genetic association and interaction between the TYK2 and IRF5 genes in systemic lupus erythematosus. J Rheumatol (2009) 2.39
Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalpha. Cell (2008) 2.25
Continuous tooth generation in mouse is induced by activated epithelial Wnt/beta-catenin signaling. Proc Natl Acad Sci U S A (2006) 2.25
p63 regulates multiple signalling pathways required for ectodermal organogenesis and differentiation. Development (2006) 2.23
Nonindependence of mammalian dental characters. Nature (2004) 2.19
Transcription factor EBF restricts alternative lineage options and promotes B cell fate commitment independently of Pax5. Nat Immunol (2008) 2.19
SUMO modification of a novel MAR-binding protein, SATB2, modulates immunoglobulin mu gene expression. Genes Dev (2003) 2.17
miR-34s inhibit osteoblast proliferation and differentiation in the mouse by targeting SATB2. J Cell Biol (2012) 2.15
Early B cell factor 1 regulates B cell gene networks by activation, repression, and transcription- independent poising of chromatin. Immunity (2010) 2.08
Regulation of mammalian tooth cusp patterning by ectodin. Science (2005) 2.05
The importance of signal pathway modulation in all aspects of tooth development. J Exp Zool B Mol Dev Evol (2009) 2.03
An integrated gene regulatory network controls stem cell proliferation in teeth. PLoS Biol (2007) 2.03
The E3 SUMO ligase PIASy is a regulator of cellular senescence and apoptosis. Mol Cell (2006) 1.90
FGF4, a direct target of LEF1 and Wnt signaling, can rescue the arrest of tooth organogenesis in Lef1(-/-) mice. Genes Dev (2002) 1.88
Tbx5 is essential for forelimb bud initiation following patterning of the limb field in the mouse embryo. Development (2003) 1.88
Stimulation of ectodermal organ development by Ectodysplasin-A1. Dev Biol (2003) 1.88
Sclerostin is a novel secreted osteoclast-derived bone morphogenetic protein antagonist with unique ligand specificity. J Biol Chem (2003) 1.86
The three mouse actin-depolymerizing factor/cofilins evolved to fulfill cell-type-specific requirements for actin dynamics. Mol Biol Cell (2002) 1.85
Distinct promoters mediate the regulation of Ebf1 gene expression by interleukin-7 and Pax5. Mol Cell Biol (2006) 1.81
LEF1-mediated regulation of Delta-like1 links Wnt and Notch signaling in somitogenesis. Genes Dev (2004) 1.76
Skeletal defects in ringelschwanz mutant mice reveal that Lrp6 is required for proper somitogenesis and osteogenesis. Development (2004) 1.74
Root or crown: a developmental choice orchestrated by the differential regulation of the epithelial stem cell niche in the tooth of two rodent species. Development (2003) 1.70
Genetic analysis of PSORS1 distinguishes guttate psoriasis and palmoplantar pustulosis. J Invest Dermatol (2003) 1.68
Satb1 and Satb2 regulate embryonic stem cell differentiation and Nanog expression. Genes Dev (2009) 1.67
Follistatin regulates enamel patterning in mouse incisors by asymmetrically inhibiting BMP signaling and ameloblast differentiation. Dev Cell (2004) 1.65
Tooth shape formation and tooth renewal: evolving with the same signals. Development (2012) 1.64
Identification of a secreted BMP antagonist, ectodin, integrating BMP, FGF, and SHH signals from the tooth enamel knot. Dev Biol (2003) 1.58
Matrix metalloproteinase-19 expression in dermal wounds and by fibroblasts in culture. J Invest Dermatol (2003) 1.57
Sox2+ stem cells contribute to all epithelial lineages of the tooth via Sfrp5+ progenitors. Dev Cell (2012) 1.57
Interactions between FGF and Wnt signals and Tbx3 gene expression in mammary gland initiation in mouse embryos. J Anat (2004) 1.55
Lef1 is required for the transition of Wnt signaling from mesenchymal to epithelial cells in the mouse embryonic mammary gland. Dev Biol (2006) 1.55
Ectodysplasin has a dual role in ectodermal organogenesis: inhibition of Bmp activity and induction of Shh expression. Development (2007) 1.53
Ectodysplasin A1 promotes placodal cell fate during early morphogenesis of ectodermal appendages. Development (2004) 1.53
LEF-1 is crucial for neutrophil granulocytopoiesis and its expression is severely reduced in congenital neutropenia. Nat Med (2006) 1.52
The role of growth factors in tooth development. Int Rev Cytol (2002) 1.52
Satb1 and Satb2 are dispensable for X chromosome inactivation in mice. Dev Cell (2012) 1.51
Functional characterization of three novel tissue-specific anion exchangers SLC26A7, -A8, and -A9. J Biol Chem (2002) 1.50
Wnt signaling interacts with Shh to regulate taste papilla development. Proc Natl Acad Sci U S A (2007) 1.50
Ectodysplasin signaling in development. Cytokine Growth Factor Rev (2003) 1.48
Risk of cervical and other cancers after treatment of cervical intraepithelial neoplasia: retrospective cohort study. BMJ (2005) 1.47
Splicing site mutations in dentin sialophosphoprotein causing dentinogenesis imperfecta type II. Eur J Oral Sci (2006) 1.42
Coding haplotype analysis supports HCR as the putative susceptibility gene for psoriasis at the MHC PSORS1 locus. Hum Mol Genet (2002) 1.42
Abnormal cervical cytology is associated with increased nitric oxide release in the uterine cervix. Acta Obstet Gynecol Scand (2009) 1.40
EBF2 regulates osteoblast-dependent differentiation of osteoclasts. Dev Cell (2005) 1.40
Transcription control of early B cell differentiation. Curr Opin Immunol (2010) 1.38
Hindgut defects and transformation of the gastro-intestinal tract in Tcf4(-/-)/Tcf1(-/-) embryos. EMBO J (2004) 1.37
Sumo-1 function is dispensable in normal mouse development. Mol Cell Biol (2008) 1.37
Runx2 mediates FGF signaling from epithelium to mesenchyme during tooth morphogenesis. Dev Biol (2004) 1.32
A missense mutation in PAX9 in a family with distinct phenotype of oligodontia. Eur J Hum Genet (2003) 1.32
Self-sample HPV tests as an intervention for nonattendees of cervical cancer screening in Finland: a randomized trial. Cancer Epidemiol Biomarkers Prev (2011) 1.27
Sustained epithelial beta-catenin activity induces precocious hair development but disrupts hair follicle down-growth and hair shaft formation. Development (2008) 1.27
A network of genetic repression and derepression specifies projection fates in the developing neocortex. Proc Natl Acad Sci U S A (2012) 1.26
IL-33 and ST2 in atopic dermatitis: expression profiles and modulation by triggering factors. J Invest Dermatol (2012) 1.25
Increased expression of beta6-integrin in skin leads to spontaneous development of chronic wounds. Am J Pathol (2004) 1.24
Integument pattern formation involves genetic and epigenetic controls: feather arrays simulated by digital hormone models. Int J Dev Biol (2004) 1.24
Progression of calvarial bone development requires Foxc1 regulation of Msx2 and Alx4. Dev Biol (2003) 1.23
Wnt10a regulates dentin sialophosphoprotein mRNA expression and possibly links odontoblast differentiation and tooth morphogenesis. Differentiation (2007) 1.22
Interactions between Shh, Sostdc1 and Wnt signaling and a new feedback loop for spatial patterning of the teeth. Development (2011) 1.21
Transcription factor EBF1 is essential for the maintenance of B cell identity and prevention of alternative fates in committed cells. Nat Immunol (2013) 1.21
Tinkering with the inductive mesenchyme: Sostdc1 uncovers the role of dental mesenchyme in limiting tooth induction. Development (2009) 1.18
The early topography of thalamocortical projections is shifted in Ebf1 and Dlx1/2 mutant mice. Development (2002) 1.18
LEF1 is a critical epithelial survival factor during tooth morphogenesis. Dev Biol (2005) 1.17
Inactivation of IL11 signaling causes craniosynostosis, delayed tooth eruption, and supernumerary teeth. Am J Hum Genet (2011) 1.17
Identification of dkk4 as a target of Eda-A1/Edar pathway reveals an unexpected role of ectodysplasin as inhibitor of Wnt signalling in ectodermal placodes. Dev Biol (2008) 1.17
Cell-type-specific function of BCL9 involves a transcriptional activation domain that synergizes with beta-catenin. Mol Cell Biol (2008) 1.17
Molecular interactions between Tbx3 and Bmp4 and a model for dorsoventral positioning of mammary gland development. Proc Natl Acad Sci U S A (2006) 1.16
Sox2 marks epithelial competence to generate teeth in mammals and reptiles. Development (2013) 1.16
The human GIMAP5 gene has a common polyadenylation polymorphism increasing risk to systemic lupus erythematosus. J Med Genet (2007) 1.16
Wnt/β-catenin signaling in the dental mesenchyme regulates incisor development by regulating Bmp4. Dev Biol (2010) 1.15
Signaling networks regulating tooth organogenesis and regeneration, and the specification of dental mesenchymal and epithelial cell lineages. Cold Spring Harb Perspect Biol (2012) 1.14
Adenomatous polyposis families that screen APC mutation-negative by conventional methods are genetically heterogeneous. J Clin Oncol (2005) 1.14
Patterns of Wnt pathway activity in the mouse incisor indicate absence of Wnt/beta-catenin signaling in the epithelial stem cells. Dev Dyn (2010) 1.13
Transcription factor Ebf1 regulates differentiation stage-specific signaling, proliferation, and survival of B cells. Genes Dev (2012) 1.13
Temporal and spatial expression of matrix metalloproteinases during wound healing of human corneal tissue. Exp Eye Res (2003) 1.13
Screening with a primary human papillomavirus test does not increase detection of cervical cancer and intraepithelial neoplasia 3. Eur J Cancer (2008) 1.12
Expression of Runx1, -2 and -3 during tooth, palate and craniofacial bone development. Mech Dev (2002) 1.11
The role of the dental lamina in mammalian tooth replacement. J Exp Zool B Mol Dev Evol (2009) 1.11
Different roles of Runx2 during early neural crest-derived bone and tooth development. J Bone Miner Res (2006) 1.10
Tooth morphogenesis and ameloblast differentiation are regulated by micro-RNAs. Dev Biol (2010) 1.10
PIASy-deficient mice display modest defects in IFN and Wnt signaling. J Immunol (2004) 1.10
Molecular mechanisms in calvarial bone and suture development, and their relation to craniosynostosis. Eur J Orthod (2003) 1.08
Phenotypic changes in dentition of Runx2 homozygote-null mutant mice. J Histochem Cytochem (2004) 1.08