Published in Circ Res on November 04, 2004
Endogenous cardiotonic steroids: physiology, pharmacology, and novel therapeutic targets. Pharmacol Rev (2009) 2.17
Upregulation of Na+/Ca2+ exchanger and TRPC6 contributes to abnormal Ca2+ homeostasis in arterial smooth muscle cells from Milan hypertensive rats. Am J Physiol Heart Circ Physiol (2010) 1.77
Endogenous digitalis: pathophysiologic roles and therapeutic applications. Nat Clin Pract Nephrol (2008) 1.35
Genetics of salt-sensitive hypertension. Curr Hypertens Rep (2011) 1.21
The dopamine paradox in lung and kidney epithelia: sharing the same target but operating different signaling networks. Am J Respir Cell Mol Biol (2005) 1.05
The regulation of proximal tubular salt transport in hypertension: an update. Curr Opin Nephrol Hypertens (2009) 1.03
Caveolin-1 and dopamine-mediated internalization of NaKATPase in human renal proximal tubule cells. Hypertension (2009) 0.98
Genetics of arterial hypertension and hypotension. Naunyn Schmiedebergs Arch Pharmacol (2007) 0.97
Phosphorylation of adaptor protein-2 mu2 is essential for Na+,K+-ATPase endocytosis in response to either G protein-coupled receptor or reactive oxygen species. Am J Respir Cell Mol Biol (2006) 0.97
Relationships among endogenous ouabain, alpha-adducin polymorphisms and renal sodium handling in primary hypertension. J Hypertens (2008) 0.97
Endogenous cardiotonic steroids and salt-sensitive hypertension. Biochim Biophys Acta (2010) 0.94
Increased arterial smooth muscle Ca2+ signaling, vasoconstriction, and myogenic reactivity in Milan hypertensive rats. Am J Physiol Heart Circ Physiol (2011) 0.92
Localization of intracellular compartments that exchange Na,K-ATPase molecules with the plasma membrane in a hormone-dependent manner. Br J Pharmacol (2007) 0.89
Trafficking of Na-K-ATPase and dopamine receptor molecules induced by changes in intracellular sodium concentration of renal epithelial cells. Am J Physiol Renal Physiol (2008) 0.89
Knockout mice reveal key roles for claudin 18 in alveolar barrier properties and fluid homeostasis. Am J Respir Cell Mol Biol (2014) 0.88
Protein kinase A-Iα regulates Na,K-ATPase endocytosis in alveolar epithelial cells exposed to high CO(2) concentrations. Am J Respir Cell Mol Biol (2013) 0.87
Targeting of renal proximal tubule Na,K-ATPase by salt-inducible kinase. Biochem Biophys Res Commun (2010) 0.87
Pals-associated tight junction protein functionally links dopamine and angiotensin II to the regulation of sodium transport in renal epithelial cells. Br J Pharmacol (2009) 0.85
Identification of a region of rat chromosome 1 that impairs the myogenic response and autoregulation of cerebral blood flow in fawn-hooded hypertensive rats. Am J Physiol Heart Circ Physiol (2012) 0.84
An α2-Na/K ATPase/α-adducin complex in astrocytes triggers non-cell autonomous neurodegeneration. Nat Neurosci (2014) 0.82
NKCC2 is activated in Milan hypertensive rats contributing to the maintenance of salt-sensitive hypertension. Pflugers Arch (2011) 0.81
Leptin and the Regulation of Renal Sodium Handling and Renal Na-Transporting ATPases: Role in the Pathogenesis of Arterial Hypertension. Curr Cardiol Rev (2010) 0.78
Elevated Aminopeptidase P Attenuates Cerebral Arterial Responses to Bradykinin in Fawn-Hooded Hypertensive Rats. PLoS One (2015) 0.77
Hypertension-linked mutation of α-adducin increases CFTR surface expression and activity in HEK and cultured rat distal convoluted tubule cells. PLoS One (2012) 0.77
Knockdown of Add3 Impairs the Myogenic Response of Renal Afferent Arterioles and Middle Cerebral Arteries. Am J Physiol Renal Physiol (2016) 0.76
Lack of salt-inducible kinase 2 (SIK2) prevents the development of cardiac hypertrophy in response to chronic high-salt intake. PLoS One (2014) 0.76
Identification of adducin-binding residues on the cytoplasmic domain of erythrocyte membrane protein, band 3. Biochem J (2016) 0.75
Ouabain Contributes to Kidney Damage in a Rat Model of Renal Ischemia-Reperfusion Injury. Int J Mol Sci (2016) 0.75
Preoperative endogenous ouabain predicts acute kidney injury in cardiac surgery patients. Crit Care Med (2013) 2.89
Carotid artery intima-media thickness and distensibility in children and adolescents: reference values and role of body dimensions. Hypertension (2013) 2.31
Hypoxia-induced endocytosis of Na,K-ATPase in alveolar epithelial cells is mediated by mitochondrial reactive oxygen species and PKC-zeta. J Clin Invest (2003) 2.14
Fluoxetine and cocaine induce the epigenetic factors MeCP2 and MBD1 in adult rat brain. Mol Pharmacol (2006) 2.13
Association of atrial natriuretic peptide and type a natriuretic peptide receptor gene polymorphisms with left ventricular mass in human essential hypertension. J Am Coll Cardiol (2006) 1.98
Essential hypertension. Lancet (2003) 1.79
Role of the adducin family genes in human essential hypertension. J Hypertens (2005) 1.62
Sodium pump alpha2 subunits control myogenic tone and blood pressure in mice. J Physiol (2005) 1.58
Epistatic interaction between alpha- and gamma-adducin influences peripheral and central pulse pressures in white Europeans. J Hypertens (2005) 1.55
Genome sequencing reveals loci under artificial selection that underlie disease phenotypes in the laboratory rat. Cell (2013) 1.53
Glomerular number and size in Milan hypertensive and normotensive rats: their relationship to susceptibility and resistance to hypertension and renal disease. J Hypertens (2004) 1.50
Histone deacetylase inhibitors decrease cocaine but not sucrose self-administration in rats. J Neurosci (2008) 1.47
Dopamine-induced exocytosis of Na,K-ATPase is dependent on activation of protein kinase C-epsilon and -delta. Mol Biol Cell (2002) 1.45
Carotid and femoral intima-media thickness in relation to three candidate genes in a Caucasian population. J Hypertens (2002) 1.44
Effects of genetic variation in adducin on left ventricular diastolic function as assessed by tissue Doppler imaging in a Flemish population. J Hypertens (2008) 1.42
Relationship between left ventricular mass and the ACE D/I polymorphism varies according to sodium intake. J Hypertens (2004) 1.40
Genetics of essential hypertension: from families to genes. J Am Soc Nephrol (2002) 1.29
Analysis of Na+,K+-ATPase motion and incorporation into the plasma membrane in response to G protein-coupled receptor signals in living cells. Mol Biol Cell (2003) 1.25
Long-term follow-up after rituximab for steroid-dependent idiopathic nephrotic syndrome. Nephrol Dial Transplant (2011) 1.24
Organ hypertrophic signaling within caveolae membrane subdomains triggered by ouabain and antagonized by PST 2238. J Biol Chem (2004) 1.22
Percutaneous CT-guided biopsy of the spine: results of 430 biopsies. Eur Spine J (2008) 1.22
Genetic screening in adolescents with steroid-resistant nephrotic syndrome. Kidney Int (2013) 1.21
Influence of calcium-sensing receptor gene on urinary calcium excretion in stone-forming patients. J Am Soc Nephrol (2002) 1.21
Phosphatidylinositol 4-kinase serves as a metabolic sensor and regulates priming of secretory granules in pancreatic beta cells. Proc Natl Acad Sci U S A (2003) 1.20
Selective arterial embolization of 36 aneurysmal bone cysts of the skeleton with N-2-butyl cyanoacrylate. Skeletal Radiol (2010) 1.20
Intracellular Na+ regulates dopamine and angiotensin II receptors availability at the plasma membrane and their cellular responses in renal epithelia. J Biol Chem (2003) 1.19
Physiological interaction between alpha-adducin and WNK1-NEDD4L pathways on sodium-related blood pressure regulation. Hypertension (2008) 1.17
Angiotensin-converting enzyme I/D and alpha-adducin Gly460Trp polymorphisms: from angiotensin-converting enzyme activity to cardiovascular outcome. Hypertension (2007) 1.17
Acute or repeated cocaine administration generates reactive oxygen species and induces antioxidant enzyme activity in dopaminergic rat brain structures. Neuropharmacology (2005) 1.15
Inositol hexakisphosphate promotes dynamin I- mediated endocytosis. Proc Natl Acad Sci U S A (2002) 1.14
Tyrosine 537 within the Na+,K+-ATPase alpha-subunit is essential for AP-2 binding and clathrin-dependent endocytosis. J Biol Chem (2002) 1.12
SIK1 is part of a cell sodium-sensing network that regulates active sodium transport through a calcium-dependent process. Proc Natl Acad Sci U S A (2007) 1.10
Common genetic variants and haplotypes in renal CLCNKA gene are associated to salt-sensitive hypertension. Hum Mol Genet (2007) 1.09
Endogenous ouabain in cardiovascular function and disease. J Hypertens (2009) 1.08
Cocaine self-administration alters the expression of chromatin-remodelling proteins; modulation by histone deacetylase inhibition. J Psychopharmacol (2009) 1.06
alpha-Adducin mutations increase Na/K pump activity in renal cells by affecting constitutive endocytosis: implications for tubular Na reabsorption. Am J Physiol Renal Physiol (2008) 1.05
Registration of trials and protocols. Lancet (2003) 1.05
Clathrin-mediated endocytosis of Na+,K+-ATPase in response to parathyroid hormone requires ERK-dependent phosphorylation of Ser-11 within the alpha1-subunit. J Biol Chem (2004) 1.04
Independent and incremental prognostic value of endogenous ouabain in idiopathic dilated cardiomyopathy. Eur J Heart Fail (2005) 1.03
Rostafuroxin: an ouabain antagonist that corrects renal and vascular Na+-K+- ATPase alterations in ouabain and adducin-dependent hypertension. Am J Physiol Regul Integr Comp Physiol (2006) 1.03
ACE and alpha-adducin polymorphism as markers of individual response to diuretic therapy. Hypertension (2003) 1.02
Istaroxime, a stimulator of sarcoplasmic reticulum calcium adenosine triphosphatase isoform 2a activity, as a novel therapeutic approach to heart failure. Am J Cardiol (2006) 1.01
Salt, endogenous ouabain and blood pressure interactions in the general population. J Hypertens (2003) 1.01
Agonist-dependent regulation of renal Na+,K+-ATPase activity is modulated by intracellular sodium concentration. J Biol Chem (2002) 1.01
The 14-3-3 protein translates the NA+,K+-ATPase {alpha}1-subunit phosphorylation signal into binding and activation of phosphoinositide 3-kinase during endocytosis. J Biol Chem (2005) 1.01
Activation of the cGMP pathway in dopaminergic structures reduces cocaine-induced EGR-1 expression and locomotor activity. J Neurosci (2004) 1.00
Pharmacogenomics and pharmacogenetics of hypertension: update and perspectives--the adducin paradigm. J Am Soc Nephrol (2006) 1.00
Involvement of SIK3 in glucose and lipid homeostasis in mice. PLoS One (2012) 0.99
Adducin- and ouabain-related gene variants predict the antihypertensive activity of rostafuroxin, part 2: clinical studies. Sci Transl Med (2010) 0.99
Relationships among endogenous ouabain, alpha-adducin polymorphisms and renal sodium handling in primary hypertension. J Hypertens (2008) 0.97
Salt, Na+,K+-ATPase and hypertension. Life Sci (2009) 0.97
Phosphorylation of adaptor protein-2 mu2 is essential for Na+,K+-ATPase endocytosis in response to either G protein-coupled receptor or reactive oxygen species. Am J Respir Cell Mol Biol (2006) 0.97
Relevance of dopamine signals anchoring dynamin-2 to the plasma membrane during Na+,K+-ATPase endocytosis. J Biol Chem (2002) 0.95
Rapid association of protein kinase C-epsilon with insulin granules is essential for insulin exocytosis. J Biol Chem (2003) 0.95
Endogenous ouabain and the renin-angiotensin-aldosterone system: distinct effects on Na handling and blood pressure in human hypertension. J Hypertens (2011) 0.95
Inhibition of Na,K-ATPase by dopamine in proximal tubule epithelial cells. Semin Nephrol (2005) 0.95
Comparison of plasma clearance of iohexol and urinary clearance of inulin for measurement of GFR in children. Am J Kidney Dis (2010) 0.95
Blocking the salt-inducible kinase 1 network prevents the increases in cell sodium transport caused by a hypertension-linked mutation in human alpha-adducin. J Hypertens (2009) 0.94
Contrary to rat-type, human-type Na,K-ATPase is phosphorylated at the same amino acid by hormones that produce opposite effects on enzyme activity. J Am Soc Nephrol (2005) 0.94
Outcome of the intramedullary diaphyseal segmental defect fixation system for bone tumors. J Surg Oncol (2011) 0.94
Histone deacetylase inhibition decreases preference without affecting aversion for nicotine. J Neurochem (2011) 0.94
CDKL5 is a brain MeCP2 target gene regulated by DNA methylation. Neurobiol Dis (2010) 0.94
Adducin- and ouabain-related gene variants predict the antihypertensive activity of rostafuroxin, part 1: experimental studies. Sci Transl Med (2010) 0.93
Association between hypertension and variation in the alpha- and beta-adducin genes in a white population. Kidney Int (2002) 0.93
Left ventricular mass in relation to genetic variation in angiotensin II receptors, renin system genes, and sodium excretion. Circulation (2004) 0.92
Autosomal dominant hypocalcemia with mild type 5 Bartter syndrome. J Nephrol (2006) 0.92
Radiofrequency thermoablation of primary non-spinal osteoid osteoma: optimization of the procedure. Eur Radiol (2005) 0.90
High circulating levels of endogenous ouabain in the offspring of hypertensive and normotensive individuals. J Hypertens (2005) 0.90
Cocaine induces the expression of MEF2C transcription factor in rat striatum through activation of SIK1 and phosphorylation of the histone deacetylase HDAC5. Synapse (2011) 0.90
alpha- and beta-Adducin polymorphisms affect podocyte proteins and proteinuria in rodents and decline of renal function in human IgA nephropathy. J Mol Med (Berl) (2009) 0.90
Trafficking of Na-K-ATPase and dopamine receptor molecules induced by changes in intracellular sodium concentration of renal epithelial cells. Am J Physiol Renal Physiol (2008) 0.89
Blood pressure in relation to three candidate genes in a Chinese population. J Hypertens (2004) 0.89
A classification method for neurogenic heterotopic ossification of the hip. J Orthop Traumatol (2012) 0.89
Gly460Trp alpha-adducin mutation as a possible mechanism leading to endolymphatic hydrops in Ménière's syndrome. Otol Neurotol (2008) 0.88
G-protein-coupled receptor-mediated traffic of Na,K-ATPase to the plasma membrane requires the binding of adaptor protein 1 to a Tyr-255-based sequence in the alpha-subunit. J Biol Chem (2008) 0.88
Left ventricular geometry and endogenous ouabain in a Flemish population. J Hypertens (2009) 0.88
FRET analysis reveals a critical conformational change within the Na,K-ATPase alpha1 subunit N-terminus during GPCR-dependent endocytosis. FEBS Lett (2006) 0.88
Expression of the methyl-CpG-binding protein MeCP2 in rat brain. An ontogenetic study. Neurobiol Dis (2004) 0.88
Intracellular sodium sensing: SIK1 network, hormone action and high blood pressure. Biochim Biophys Acta (2010) 0.88