Published in J Clin Endocrinol Metab on November 01, 2004
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Cord blood leptin levels of healthy neonates are associated with IFN-γ production by cord blood T-cells. PLoS One (2012) 0.76
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Effect of zinc supplementation on body mass index and serum levels of zinc and leptin in pediatric hemodialysis patients. Int J Nephrol Renovasc Dis (2015) 0.75
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Global transcriptome analysis identifies differentially expressed genes related to lipid metabolism in Wagyu and Holstein cattle. Sci Rep (2017) 0.75
Fingerprints of global warming on wild animals and plants. Nature (2003) 19.85
Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans. J Lipid Res (2005) 11.88
Complexity of coupled human and natural systems. Science (2007) 7.53
Adipocyte death, adipose tissue remodeling, and obesity complications. Diabetes (2007) 6.11
Emissions pathways, climate change, and impacts on California. Proc Natl Acad Sci U S A (2004) 6.04
Expert credibility in climate change. Proc Natl Acad Sci U S A (2010) 5.42
Effect of rosiglitazone treatment on nontraditional markers of cardiovascular disease in patients with type 2 diabetes mellitus. Circulation (2002) 3.96
Coupled human and natural systems. Ambio (2007) 3.72
Probabilistic integrated assessment of "dangerous" climate change. Science (2004) 3.37
Climate change, elevational range shifts, and bird extinctions. Conserv Biol (2008) 2.86
Human-modified temperatures induce species changes: Joint attribution. Proc Natl Acad Sci U S A (2005) 2.79
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Dynamic, M2-like remodeling phenotypes of CD11c+ adipose tissue macrophages during high-fat diet--induced obesity in mice. Diabetes (2010) 2.76
Assessing dangerous climate change through an update of the Intergovernmental Panel on Climate Change (IPCC) "reasons for concern". Proc Natl Acad Sci U S A (2009) 2.72
Analysis of lipolytic protein trafficking and interactions in adipocytes. J Biol Chem (2006) 2.70
Retinol binding protein 4 expression in humans: relationship to insulin resistance, inflammation, and response to pioglitazone. J Clin Endocrinol Metab (2007) 2.58
Identification of omentin as a novel depot-specific adipokine in human adipose tissue: possible role in modulating insulin action. Am J Physiol Endocrinol Metab (2006) 2.47
Control of adipose triglyceride lipase action by serine 517 of perilipin A globally regulates protein kinase A-stimulated lipolysis in adipocytes. J Biol Chem (2006) 2.45
Estrogen regulation of adiposity and fuel partitioning. Evidence of genomic and non-genomic regulation of lipogenic and oxidative pathways. J Biol Chem (2005) 2.33
Progressive vascular smooth muscle cell defects in a mouse model of Hutchinson-Gilford progeria syndrome. Proc Natl Acad Sci U S A (2006) 2.28
Diabetes mellitus increases short-term mortality and morbidity in patients undergoing coronary artery bypass graft surgery. J Am Coll Cardiol (2002) 2.23
Adipocytokines and insulin resistance. J Clin Endocrinol Metab (2004) 2.16
Perilipin promotes hormone-sensitive lipase-mediated adipocyte lipolysis via phosphorylation-dependent and -independent mechanisms. J Biol Chem (2006) 2.15
Reduced energy expenditure and increased inflammation are early events in the development of ovariectomy-induced obesity. Endocrinology (2009) 2.10
T-cell recruitment and Th1 polarization in adipose tissue during diet-induced obesity in C57BL/6 mice. Obesity (Silver Spring) (2010) 2.09
Adipose tissue heterogeneity: implication of depot differences in adipose tissue for obesity complications. Mol Aspects Med (2012) 2.07
AMP-activated protein kinase is activated as a consequence of lipolysis in the adipocyte: potential mechanism and physiological relevance. J Biol Chem (2008) 2.02
Tumor necrosis factor-alpha stimulates lipolysis in differentiated human adipocytes through activation of extracellular signal-related kinase and elevation of intracellular cAMP. Diabetes (2002) 2.00
Omentin plasma levels and gene expression are decreased in obesity. Diabetes (2007) 1.98
Cardiovascular pathology in Hutchinson-Gilford progeria: correlation with the vascular pathology of aging. Arterioscler Thromb Vasc Biol (2010) 1.96
Modulation of hormone-sensitive lipase and protein kinase A-mediated lipolysis by perilipin A in an adenoviral reconstituted system. J Biol Chem (2001) 1.90
Adipose triglyceride lipase is a major hepatic lipase that regulates triacylglycerol turnover and fatty acid signaling and partitioning. Hepatology (2010) 1.84
Increased cancer-related mortality for patients with type 2 diabetes who use sulfonylureas or insulin: Response to Bowker et Al. Diabetes Care (2006) 1.84
Acute-phase serum amyloid A: an inflammatory adipokine and potential link between obesity and its metabolic complications. PLoS Med (2006) 1.81
Multidimensional evaluation of managed relocation. Proc Natl Acad Sci U S A (2009) 1.79
Regulatory role for the arginine-nitric oxide pathway in metabolism of energy substrates. J Nutr Biochem (2006) 1.77
miR-130 suppresses adipogenesis by inhibiting peroxisome proliferator-activated receptor gamma expression. Mol Cell Biol (2010) 1.75
LPAM (alpha 4 beta 7 integrin) is an important homing integrin on alloreactive T cells in the development of intestinal graft-versus-host disease. Blood (2003) 1.67
Thrombospondin-1 is an adipokine associated with obesity, adipose inflammation, and insulin resistance. Diabetes (2007) 1.67
Consequences of lipid droplet coat protein downregulation in liver cells: abnormal lipid droplet metabolism and induction of insulin resistance. Diabetes (2008) 1.65
Sex differences in human adipose tissues - the biology of pear shape. Biol Sex Differ (2012) 1.64
IL-7 enhances peripheral T cell reconstitution after allogeneic hematopoietic stem cell transplantation. J Clin Invest (2003) 1.56
Climate policy: role of scientists in public advocacy. Nature (2010) 1.52
Coping with uncertainty: a call for a new science-policy forum. Ambio (2003) 1.51
Hepatic triacylglycerol hydrolysis regulates peroxisome proliferator-activated receptor alpha activity. J Lipid Res (2009) 1.50
Altered autophagy in human adipose tissues in obesity. J Clin Endocrinol Metab (2010) 1.47
Donor T cell-derived TNF is required for graft-versus-host disease and graft-versus-tumor activity after bone marrow transplantation. Blood (2002) 1.47
Lipase-selective functional domains of perilipin A differentially regulate constitutive and protein kinase A-stimulated lipolysis. J Biol Chem (2003) 1.45
Human visfatin expression: relationship to insulin sensitivity, intramyocellular lipids, and inflammation. J Clin Endocrinol Metab (2006) 1.42
Dietary blueberry attenuates whole-body insulin resistance in high fat-fed mice by reducing adipocyte death and its inflammatory sequelae. J Nutr (2009) 1.41
Altered metabolic responses to intermittent hypoxia in mice with partial deficiency of hypoxia-inducible factor-1alpha. Physiol Genomics (2006) 1.38
Adipose tissue remodeling in pathophysiology of obesity. Curr Opin Clin Nutr Metab Care (2010) 1.37
Adipose triglyceride lipase regulates basal lipolysis and lipid droplet size in adipocytes. J Cell Biochem (2008) 1.36
Does patient blood glucose monitoring improve diabetes control? A systematic review of the literature. Diabetes Educ (2007) 1.36
Key role for ceramides in mediating insulin resistance in human muscle cells. J Biol Chem (2007) 1.35
T cells require TRAIL for optimal graft-versus-tumor activity. Nat Med (2002) 1.35
Increased apoptosis in high-fat diet-induced nonalcoholic steatohepatitis in rats is associated with c-Jun NH2-terminal kinase activation and elevated proapoptotic Bax. J Nutr (2008) 1.26
Obese subjects carrying the 11482G>A polymorphism at the perilipin locus are resistant to weight loss after dietary energy restriction. J Clin Endocrinol Metab (2005) 1.26
Perilipin-2-null mice are protected against diet-induced obesity, adipose inflammation, and fatty liver disease. J Lipid Res (2013) 1.25
Subcutaneous adipose tissue macrophage infiltration is associated with hepatic and visceral fat deposition, hyperinsulinemia, and stimulation of NF-κB stress pathway. Diabetes (2011) 1.24
Physical activity/exercise and diabetes mellitus. Diabetes Care (2003) 1.24
Impact of a health promotion program on employee health risks and work productivity. Am J Health Promot (2007) 1.22
Effect of thiazolidinediones on glucose and fatty acid metabolism in patients with type 2 diabetes. Metabolism (2003) 1.21
Dietary L-arginine supplementation reduces white fat gain and enhances skeletal muscle and brown fat masses in diet-induced obese rats. J Nutr (2008) 1.19
Increased systemic and adipose tissue cytokines in patients with HIV-associated lipodystrophy. Am J Physiol Endocrinol Metab (2003) 1.19
Estradiol stimulates Akt, AMP-activated protein kinase (AMPK) and TBC1D1/4, but not glucose uptake in rat soleus. Biochem Biophys Res Commun (2009) 1.19
Total costs of IBS: employer and managed care perspective. Am J Manag Care (2005) 1.19
Clinical resolution of glycogenic hepatopathy following improved glycemic control. J Diabetes Complications (2008) 1.18
TNF-alpha induction of lipolysis is mediated through activation of the extracellular signal related kinase pathway in 3T3-L1 adipocytes. J Cell Biochem (2003) 1.18
Nonalcoholic steatohepatitis induced by a high-fat diet promotes diethylnitrosamine-initiated early hepatocarcinogenesis in rats. Int J Cancer (2009) 1.18
Integration of hormonal and nutrient signals that regulate leptin synthesis and secretion. Am J Physiol Endocrinol Metab (2009) 1.17
Gender-specific association of a perilipin gene haplotype with obesity risk in a white population. Obes Res (2004) 1.17
Distinct developmental signatures of human abdominal and gluteal subcutaneous adipose tissue depots. J Clin Endocrinol Metab (2012) 1.17
Regulation of adipocyte lipolysis by degradation of the perilipin protein: nelfinavir enhances lysosome-mediated perilipin proteolysis. J Biol Chem (2007) 1.16
A modified protocol to maximize differentiation of human preadipocytes and improve metabolic phenotypes. Obesity (Silver Spring) (2012) 1.15
Depot-specific regulation of the conversion of cortisone to cortisol in human adipose tissue. Obesity (Silver Spring) (2008) 1.15
Diet-induced obesity elevates colonic TNF-α in mice and is accompanied by an activation of Wnt signaling: a mechanism for obesity-associated colorectal cancer. J Nutr Biochem (2011) 1.14
A low-glycemic load diet facilitates greater weight loss in overweight adults with high insulin secretion but not in overweight adults with low insulin secretion in the CALERIE Trial. Diabetes Care (2005) 1.14
Functional interaction of hormone-sensitive lipase and perilipin in lipolysis. J Lipid Res (2009) 1.14
Perilipin expression in human adipose tissues: effects of severe obesity, gender, and depot. Obes Res (2003) 1.14
Identification of novel serological biomarkers for inflammatory bowel disease using Escherichia coli proteome chip. Mol Cell Proteomics (2009) 1.14
Intragenic linkage disequilibrium structure of the human perilipin gene (PLIN) and haplotype association with increased obesity risk in a multiethnic Asian population. J Mol Med (Berl) (2005) 1.13
Effects of weight loss intervention on erectile function in older men with type 2 diabetes in the Look AHEAD trial. J Sex Med (2009) 1.13
Pathways regulated by glucocorticoids in omental and subcutaneous human adipose tissues: a microarray study. Am J Physiol Endocrinol Metab (2010) 1.11
Conservation and climate change: the challenges ahead. Conserv Biol (2006) 1.10
Genetic and environmental influences on factors associated with cardiovascular disease and the metabolic syndrome. J Lipid Res (2009) 1.10
The effects of the dietary glycemic load on type 2 diabetes risk factors during weight loss. Obesity (Silver Spring) (2006) 1.09
Primary care patients reporting concerns about their gambling frequently have other co-occurring lifestyle and mental health issues. BMC Fam Pract (2006) 1.09
Potential role of autophagy in modulation of lipid metabolism. Am J Physiol Endocrinol Metab (2009) 1.08
Perilipin overexpression in mice protects against diet-induced obesity. J Lipid Res (2009) 1.07
Lifestyle screening: development of an acceptable multi-item general practice tool. N Z Med J (2004) 1.07
Case finding of lifestyle and mental health disorders in primary care: validation of the 'CHAT' tool. Br J Gen Pract (2008) 1.05
FSP27 and PLIN1 interaction promotes the formation of large lipid droplets in human adipocytes. Biochem Biophys Res Commun (2013) 1.04