Kristopher G Virga

Author PubWeight™ 9.18^‹?›

Rank	Title	Journal	Year	PubWeight™‹?›
1	Chemical knockout of pantothenate kinase reveals the metabolic and genetic program responsible for hepatic coenzyme A homeostasis.	Chem Biol	2007	1.35
2	Acyl carrier protein is a cellular target for the antibacterial action of the pantothenamide class of pantothenate antimetabolites.	J Biol Chem	2004	1.33
3	A pantothenate kinase from Staphylococcus aureus refractory to feedback regulation by coenzyme A.	J Biol Chem	2004	1.17
4	Pantothenamides are potent, on-target inhibitors of Plasmodium falciparum growth when serum pantetheinase is inactivated.	PLoS One	2013	1.07
5	The structure of the pantothenate kinase.ADP.pantothenate ternary complex reveals the relationship between the binding sites for substrate, allosteric regulator, and antimetabolites.	J Biol Chem	2004	1.01
6	Discovery of non-carbohydrate inhibitors of aminoglycoside-modifying enzymes.	Bioorg Med Chem	2005	0.96
7	Synthesis of bi-substrate state mimics of dihydropteroate synthase as potential inhibitors and molecular probes.	Bioorg Med Chem	2010	0.82
8	Development of an etoposide prodrug for dual prodrug-enzyme antitumor therapy.	Mol Cancer Ther	2006	0.77
9	Diastereoselective synthesis of a spironoraristeromycin using an acylnitroso Diels-Alder reaction.	J Org Chem	2009	0.76