R Elwyn Isaac

Author PubWeight™ 34.73‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Individuals with mutations in XPNPEP3, which encodes a mitochondrial protein, develop a nephronophthisis-like nephropathy. J Clin Invest 2010 1.20
2 Peptidomics and peptide hormone processing in the Drosophila midgut. J Proteome Res 2011 1.18
3 Proteomic identification of Drosophila melanogaster male accessory gland proteins, including a pro-cathepsin and a soluble gamma-glutamyl transpeptidase. Proteome Sci 2006 1.14
4 An essential role in molting and morphogenesis of Caenorhabditis elegans for ACN-1, a novel member of the angiotensin-converting enzyme family that lacks a metallopeptidase active site. J Biol Chem 2003 1.06
5 High-resolution crystal structures of Drosophila melanogaster angiotensin-converting enzyme in complex with novel inhibitors and antihypertensive drugs. J Mol Biol 2010 0.95
6 The drosophila angiotensin-converting enzyme homologue Ance is required for spermiogenesis. Dev Biol 2003 0.94
7 Molecular recognition and regulation of human angiotensin-I converting enzyme (ACE) activity by natural inhibitory peptides. Sci Rep 2012 0.91
8 The Caenorhabditis elegans orthologue of mammalian puromycin-sensitive aminopeptidase has roles in embryogenesis and reproduction. J Biol Chem 2003 0.90
9 Neuronal expression of tachykinin-related peptides and gene transcript during postembryonic development of Drosophila. J Comp Neurol 2003 0.90
10 Identification of a proctolin preprohormone gene (Proct) of Drosophila melanogaster: expression and predicted prohormone processing. J Neurobiol 2004 0.90
11 Bioinformatic analysis of the neprilysin (M13) family of peptidases reveals complex evolutionary and functional relationships. BMC Evol Biol 2008 0.90
12 Crystal structure of a phosphonotripeptide K-26 in complex with angiotensin converting enzyme homologue (AnCE) from Drosophila melanogaster. Biochem Biophys Res Commun 2010 0.89
13 Identification and mutational analysis of amino acid residues involved in dipyridamole interactions with human and Caenorhabditis elegans equilibrative nucleoside transporters. J Biol Chem 2005 0.88
14 Male accessory glands of Drosophila melanogaster make a secreted angiotensin I-converting enzyme (ANCE), suggesting a role for the peptide-processing enzyme in seminal fluid. J Exp Biol 2007 0.87
15 ACE inhibitors reduce fecundity in the mosquito, Anopheles stephensi. Comp Biochem Physiol B Biochem Mol Biol 2003 0.87
16 Mechanisms of parasite-induced sex reversal in Gammarus duebeni. Int J Parasitol 2004 0.86
17 Locomotor and geotactic behavior of Drosophila melanogaster over-expressing neprilysin 2. Peptides 2008 0.86
18 Unravelling the moulting degradome: new opportunities for chemotherapy? Trends Parasitol 2007 0.86
19 Biostable beta-amino acid PK/PBAN analogs: agonist and antagonist properties. Peptides 2008 0.86
20 The host-seeking inhibitory peptide, Aea-HP-1, is made in the male accessory gland and transferred to the female during copulation. Peptides 2011 0.86
21 Biostable agonists that match or exceed activity of native insect kinins on recombinant arthropod GPCRs. Gen Comp Endocrinol 2008 0.86
22 An analysis of the Caenorhabditis elegans lipid raft proteome using geLC-MS/MS. J Proteomics 2010 0.84
23 Drosophila melanogaster NEP2 is a new soluble member of the neprilysin family of endopeptidases with implications for reproduction and renal function. Biochem J 2005 0.84
24 Beta-amino acid analogs of an insect neuropeptide feature potent bioactivity and resistance to peptidase hydrolysis. Biopolymers 2007 0.84
25 Ance, a Drosophila angiotensin-converting enzyme homologue, is expressed in imaginal cells during metamorphosis and is regulated by the steroid, 20-hydroxyecdysone. Biochem J 2002 0.83
26 Functional genomics of parasitic worms: the dawn of a new era. Parasitol Int 2002 0.82
27 The angiotensin-converting enzyme (ACE) gene family of Anopheles gambiae. BMC Genomics 2005 0.82
28 Peptidyl dipeptidases (Ance and Acer) of Drosophila melanogaster: major differences in the substrate specificity of two homologs of human angiotensin I-converting enzyme. Peptides 2002 0.81
29 Structural diversity of angiotensin-converting enzyme. FEBS J 2006 0.81
30 Biostable multi-Aib analogs of tachykinin-related peptides demonstrate potent oral aphicidal activity in the pea aphid Acyrthosiphon pisum (Hemiptera: Aphidae). Peptides 2010 0.80
31 Loss of Angiotensin-converting enzyme-related (ACER) peptidase disrupts night-time sleep in adult Drosophila melanogaster. J Exp Biol 2011 0.80
32 The PAM-1 aminopeptidase regulates centrosome positioning to ensure anterior-posterior axis specification in one-cell C. elegans embryos. Dev Biol 2010 0.80
33 Expression and characterisation of a Psoroptes ovis glutathione S-transferase. Vet Parasitol 2002 0.78
34 Expression of NEP2, a soluble neprilysin-like endopeptidase, during embryogenesis in Drosophila melanogaster. Peptides 2006 0.78
35 Structural characterization of angiotensin I-converting enzyme in complex with a selenium analogue of captopril. FEBS J 2011 0.78
36 Crystal structures of highly specific phosphinic tripeptide enantiomers in complex with the angiotensin-I converting enzyme. FEBS J 2013 0.78
37 Extracellular peptidases of imaginal discs of Drosophila melanogaster. Peptides 2002 0.77
38 Functional redundancy of two nucleoside transporters of the ENT family (CeENT1, CeENT2) required for development of Caenorhabditis elegans. Mol Membr Biol 2004 0.77
39 Diverse in- and output polarities and high complexity of local synaptic and non-synaptic signaling within a chemically defined class of peptidergic Drosophila neurons. Front Neural Circuits 2013 0.77
40 Structural basis of peptide recognition by the angiotensin-1 converting enzyme homologue AnCE from Drosophila melanogaster. FEBS J 2012 0.76