Published in Biochem Biophys Res Commun on July 01, 2010
Different in vivo functions of the two catalytic domains of angiotensin-converting enzyme (ACE). Curr Opin Pharmacol (2010) 0.93
N-acetyl-seryl-aspartyl-lysyl-proline: a valuable endogenous anti-fibrotic peptide for combating kidney fibrosis in diabetes. Front Pharmacol (2014) 0.86
The antibiotic dehydrophos is converted to a toxic pyruvate analog by peptide bond cleavage in Salmonella enterica. Antimicrob Agents Chemother (2011) 0.86
Interkingdom pharmacology of Angiotensin-I converting enzyme inhibitor phosphonates produced by actinomycetes. ACS Med Chem Lett (2014) 0.83
The biological significance of angiotensin-converting enzyme inhibition to combat kidney fibrosis. Clin Exp Nephrol (2014) 0.77
Crystal structure of a peptidyl-dipeptidase K-26-DCP from Actinomycete in complex with its natural inhibitor. FEBS J (2016) 0.75
The toxicity of angiotensin converting enzyme inhibitors to larvae of the disease vectors Aedes aegypti and Anopheles gambiae. Sci Rep (2017) 0.75
A new high-resolution crystal structure of the Drosophila melanogaster angiotensin converting enzyme homologue, AnCE. FEBS Open Bio (2015) 0.75
ANG mutations segregate with familial and 'sporadic' amyotrophic lateral sclerosis. Nat Genet (2006) 3.88
The CCN family of proteins: structure-function relationships. Trends Biochem Sci (2008) 2.82
Crystal structure of the human angiotensin-converting enzyme-lisinopril complex. Nature (2003) 2.78
A genomics-guided approach for discovering and expressing cryptic metabolic pathways. Nat Biotechnol (2003) 2.41
The calicheamicin gene cluster and its iterative type I enediyne PKS. Science (2002) 2.40
CO(2) capture by a task-specific ionic liquid. J Am Chem Soc (2002) 2.04
Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example. J Nat Prod (2005) 1.88
Structural details on the binding of antihypertensive drugs captopril and enalaprilat to human testicular angiotensin I-converting enzyme. Biochemistry (2004) 1.86
Botulinum and tetanus neurotoxins: structure, function and therapeutic utility. Trends Biochem Sci (2002) 1.85
A robust two-dimensional separation for top-down tandem mass spectrometry of the low-mass proteome. J Am Soc Mass Spectrom (2009) 1.65
Identification of the protein receptor binding site of botulinum neurotoxins B and G proves the double-receptor concept. Proc Natl Acad Sci U S A (2006) 1.41
Human angiogenin is a neuroprotective factor and amyotrophic lateral sclerosis associated angiogenin variants affect neurite extension/pathfinding and survival of motor neurons. Hum Mol Genet (2007) 1.40
The IsdG-family of haem oxygenases degrades haem to a novel chromophore. Mol Microbiol (2010) 1.40
Novel Brønsted acidic ionic liquids and their use as dual solvent-catalysts. J Am Chem Soc (2002) 1.32
A proteomics approach to discovering natural products and their biosynthetic pathways. Nat Biotechnol (2009) 1.29
Ace revisited: a new target for structure-based drug design. Nat Rev Drug Discov (2003) 1.27
Cwp84, a surface-associated cysteine protease, plays a role in the maturation of the surface layer of Clostridium difficile. J Biol Chem (2009) 1.25
Structural basis of ordered binding of donor and acceptor substrates to the retaining glycosyltransferase, alpha-1,3-galactosyltransferase. J Biol Chem (2002) 1.24
Benzodiazepine biosynthesis in Streptomyces refuineus. Chem Biol (2007) 1.21
Crystal structure of an active form of human MMP-1. J Mol Biol (2006) 1.20
Individuals with mutations in XPNPEP3, which encodes a mitochondrial protein, develop a nephronophthisis-like nephropathy. J Clin Invest (2010) 1.20
The role of ADAM10 and ADAM17 in the ectodomain shedding of angiotensin converting enzyme and the amyloid precursor protein. Eur J Biochem (2004) 1.18
Peptidomics and peptide hormone processing in the Drosophila midgut. J Proteome Res (2011) 1.18
The emerging process of Top Down mass spectrometry for protein analysis: biomarkers, protein-therapeutics, and achieving high throughput. Mol Biosyst (2010) 1.16
Proteomic identification of Drosophila melanogaster male accessory gland proteins, including a pro-cathepsin and a soluble gamma-glutamyl transpeptidase. Proteome Sci (2006) 1.14
Crystal structure of the N domain of human somatic angiotensin I-converting enzyme provides a structural basis for domain-specific inhibitor design. J Mol Biol (2006) 1.12
Charcot-Leyden crystal protein (galectin-10) is not a dual function galectin with lysophospholipase activity but binds a lysophospholipase inhibitor in a novel structural fashion. J Biol Chem (2002) 1.12
Characterization of human angiogenin variants implicated in amyotrophic lateral sclerosis. Biochemistry (2007) 1.12
Crystal structure of the catalytic domain of matrix metalloproteinase-1 in complex with the inhibitory domain of tissue inhibitor of metalloproteinase-1. J Biol Chem (2006) 1.12
Sweet success: Ionic liquids derived from non-nutritive sweeteners. Chem Commun (Camb) (2004) 1.09
Proteomics-based discovery of koranimine, a cyclic imine natural product. J Am Chem Soc (2011) 1.09
The first pilot project of the consortium for top-down proteomics: a status report. Proteomics (2014) 1.08
Constraining specificity in the N-domain of tissue inhibitor of metalloproteinases-1; gelatinase-selective inhibitors. Protein Sci (2007) 1.08
Roles of individual enzyme-substrate interactions by alpha-1,3-galactosyltransferase in catalysis and specificity. Biochemistry (2003) 1.08
Antimicrobial drug resistance affects broad changes in metabolomic phenotype in addition to secondary metabolism. Proc Natl Acad Sci U S A (2013) 1.07
Deglycosylation, processing and crystallization of human testis angiotensin-converting enzyme. Biochem J (2003) 1.06
An essential role in molting and morphogenesis of Caenorhabditis elegans for ACN-1, a novel member of the angiotensin-converting enzyme family that lacks a metallopeptidase active site. J Biol Chem (2003) 1.06
Crystal structures of oligomeric forms of the IP-10/CXCL10 chemokine. Structure (2003) 1.06
Conformational changes induced by binding UDP-2F-galactose to alpha-1,3 galactosyltransferase- implications for catalysis. J Mol Biol (2007) 1.05
Super toxins from a super bug: structure and function of Clostridium difficile toxins. Biochem J (2011) 1.05
Angiotensin-converting enzyme-2 (ACE2): comparative modeling of the active site, specificity requirements, and chloride dependence. Biochemistry (2003) 1.04
Nine enzymes are required for assembly of the pacidamycin group of peptidyl nucleoside antibiotics. J Am Chem Soc (2011) 1.04
The N domain of human angiotensin-I-converting enzyme: the role of N-glycosylation and the crystal structure in complex with an N domain-specific phosphinic inhibitor, RXP407. J Biol Chem (2010) 1.03
The catalytic cycle of beta -lactam synthetase observed by x-ray crystallographic snapshots. Proc Natl Acad Sci U S A (2002) 1.02
Superantigens: structure-function relationships. Int J Med Microbiol (2004) 1.01
A proteomic survey of nonribosomal peptide and polyketide biosynthesis in actinobacteria. J Proteome Res (2011) 1.01
Structural and molecular insights into the mechanism of action of human angiogenin-ALS variants in neurons. Nat Commun (2012) 1.00
Structural basis for substrate recognition in the enzymatic component of ADP-ribosyltransferase toxin CDTa from Clostridium difficile. J Biol Chem (2009) 1.00
Human dendritic cells conditioned with Staphylococcus aureus enterotoxin B promote TH2 cell polarization. J Allergy Clin Immunol (2006) 1.00
A continuous fluorescence resonance energy transfer angiotensin I-converting enzyme assay. Nat Protoc (2006) 0.99
tRNA-dependent peptide bond formation by the transferase PacB in biosynthesis of the pacidamycin group of pentapeptidyl nucleoside antibiotics. Proc Natl Acad Sci U S A (2011) 0.99
Lipophilic mediated assays for beta-hematin inhibitors. Comb Chem High Throughput Screen (2010) 0.99
Identification of placenta growth factor determinants for binding and activation of Flt-1 receptor. J Biol Chem (2004) 0.99
High-resolution crystal structures of ribonuclease A complexed with adenylic and uridylic nucleotide inhibitors. Implications for structure-based design of ribonucleolytic inhibitors. Protein Sci (2003) 0.99
Optimizing capillary electrophoresis for top-down proteomics of 30-80 kDa proteins. Proteomics (2014) 0.98
Soluble LDL-R are formed by cell surface cleavage in response to phorbol esters. Eur J Biochem (2004) 0.97
Biosynthetic origins of C-P bond containing tripeptide K-26. Org Lett (2005) 0.97
Roles of active site tryptophans in substrate binding and catalysis by alpha-1,3 galactosyltransferase. Glycobiology (2004) 0.97
Molecular recognition of an ADP-ribosylating Clostridium botulinum C3 exoenzyme by RalA GTPase. Proc Natl Acad Sci U S A (2005) 0.96
Cell-free protein synthesis from a release factor 1 deficient Escherichia coli activates efficient and multiple site-specific nonstandard amino acid incorporation. ACS Synth Biol (2014) 0.96
A unifying nitrososynthase involved in nitrosugar biosynthesis. J Am Chem Soc (2008) 0.96
The crystal structure of C3stau2 from Staphylococcus aureus and its complex with NAD. J Biol Chem (2003) 0.95
High-resolution crystal structures of Drosophila melanogaster angiotensin-converting enzyme in complex with novel inhibitors and antihypertensive drugs. J Mol Biol (2010) 0.95
The drosophila angiotensin-converting enzyme homologue Ance is required for spermiogenesis. Dev Biol (2003) 0.94
Phenotypic mapping of metabolic profiles using self-organizing maps of high-dimensional mass spectrometry data. Anal Chem (2014) 0.93
The crystal structure of human angiogenin in complex with an antitumor neutralizing antibody. Structure (2003) 0.92
Chimeric microtubule disruptors. Chem Commun (Camb) (2010) 0.92
A high-throughput fluorimetric assay for angiotensin I-converting enzyme. Nat Protoc (2006) 0.92
Combined chemical and biosynthetic route to access a new apoptolidin congener. Org Lett (2009) 0.91
Crystal structures of Erythrina cristagalli lectin with bound N-linked oligosaccharide and lactose. Glycobiology (2004) 0.91
Molecular recognition and regulation of human angiotensin-I converting enzyme (ACE) activity by natural inhibitory peptides. Sci Rep (2012) 0.91
Expression, purification and cell cytotoxicity of actin-modifying binary toxin from Clostridium difficile. Protein Expr Purif (2010) 0.90
The Caenorhabditis elegans orthologue of mammalian puromycin-sensitive aminopeptidase has roles in embryogenesis and reproduction. J Biol Chem (2003) 0.90
The structure of testis angiotensin-converting enzyme in complex with the C domain-specific inhibitor RXPA380. Biochemistry (2007) 0.90
Tying the knot: the cystine signature and molecular-recognition processes of the vascular endothelial growth factor family of angiogenic cytokines. FEBS J (2011) 0.90
Crystal structure of protoporphyrinogen oxidase from Myxococcus xanthus and its complex with the inhibitor acifluorfen. J Biol Chem (2006) 0.90
Identification of a proctolin preprohormone gene (Proct) of Drosophila melanogaster: expression and predicted prohormone processing. J Neurobiol (2004) 0.90
Bioinformatic analysis of the neprilysin (M13) family of peptidases reveals complex evolutionary and functional relationships. BMC Evol Biol (2008) 0.90
Structure of mouse IP-10, a chemokine. Acta Crystallogr D Biol Crystallogr (2008) 0.90
Neuronal expression of tachykinin-related peptides and gene transcript during postembryonic development of Drosophila. J Comp Neurol (2003) 0.90
Assessing directed evolution methods for the generation of biosynthetic enzymes with potential in drug biosynthesis. Future Med Chem (2011) 0.90
Design and directed evolution of a dideoxy purine nucleoside phosphorylase. Protein Eng Des Sel (2010) 0.89
Atomic resolution (0.98 A) structure of eosinophil-derived neurotoxin. Biochemistry (2002) 0.89
Role of placenta growth factor in cardiovascular health. Trends Cardiovasc Med (2002) 0.89
Autopilot: an online data acquisition control system for the enhanced high-throughput characterization of intact proteins. Anal Chem (2014) 0.89
Bioactive oligosaccharide natural products. Nat Prod Rep (2014) 0.89