Association of cholesterol with stroke risk varies in stroke subtypes and patient subgroups.

PubWeight™: 1.72‹?› | Rank: Top 3%

🔗 View Article (PMID 15557504)

Published in Neurology on November 23, 2004

Authors

D L Tirschwell1, N L Smith, S R Heckbert, R N Lemaitre, W T Longstreth, B M Psaty

Author Affiliations

1: Department of Neurology, University of Washington, Seattle, USA. tirsch@u.washington.edu

Associated clinical trials:

Antihypertensive Drug/Gene Interactions and CV Events | NCT00005332

Mutations, Hormone Therapy (HRT) and Venous Thromboembolism | NCT00005515

Hormone Replacement Therapy and Prothrombotic Variants | NCT00049933

Articles citing this

Heart disease and stroke statistics--2014 update: a report from the American Heart Association. Circulation (2013) 28.02

Major lipids, apolipoproteins, and risk of vascular disease. JAMA (2009) 10.58

Heart Disease and Stroke Statistics-2017 Update: A Report From the American Heart Association. Circulation (2017) 2.76

Lipid profile components and risk of ischemic stroke: the Northern Manhattan Study (NOMAS). Arch Neurol (2009) 1.74

Hypercholesterolemia among apparently healthy university students. Oman Med J (2012) 1.42

The relative strength of C-reactive protein and lipid levels as determinants of ischemic stroke compared with coronary heart disease in women. J Am Coll Cardiol (2006) 1.36

Lipid levels and the risk of ischemic stroke in women. Neurology (2007) 1.23

Hyperlipidemia and reduced white matter hyperintensity volume in patients with ischemic stroke. Stroke (2010) 1.17

Stroke epidemiology: advancing our understanding of disease mechanism and therapy. Neurotherapeutics (2011) 1.16

Lipids and carotid plaque in the Northern Manhattan Study (NOMAS). BMC Cardiovasc Disord (2009) 1.04

Stroke prevention: modifying risk factors. Ther Adv Cardiovasc Dis (2008) 0.99

Trans fat, aspirin, and ischemic stroke in postmenopausal women. Ann Neurol (2012) 0.95

Reducing the risk of stroke in type 2 diabetes: pathophysiological and therapeutic perspectives. J Neurol (2009) 0.91

Lipid profile components and subclinical cerebrovascular disease in the northern Manhattan study. Cerebrovasc Dis (2014) 0.88

Treatment of risk factors to prevent stroke. Neurotherapeutics (2011) 0.86

Safety of statins: an update. Ther Adv Drug Saf (2012) 0.86

Lipid and lipoprotein measurements and the risk of ischemic vascular events: Framingham Study. Neurology (2015) 0.86

Risk Factors Associated With Incident Cerebral Microbleeds According to Location in Older People: The Age, Gene/Environment Susceptibility (AGES)-Reykjavik Study. JAMA Neurol (2015) 0.84

Lipid profile, statin use, and outcome after intravenous thrombolysis for acute ischaemic stroke. J Neurol (2008) 0.84

Risk factors for primary intracerebral hemorrhage in patients in Izumo City, Japan. Neurosurg Rev (2007) 0.84

Comparison of Risk Factor between Lacunar Stroke and Large Artery Atherosclerosis Stroke: A Cross-Sectional Study in China. PLoS One (2016) 0.80

Stroke Risk Factors, Genetics, and Prevention. Circ Res (2017) 0.78

Racial differences in the association of insulin resistance with stroke risk: the REasons for Geographic And Racial Differences in Stroke (REGARDS) study. Stroke (2014) 0.78

Acute Statin Treatment Improves Recovery after Experimental Intracerebral Hemorrhage. World J Neurosci (2013) 0.78

Lipids and Cerebrovascular Disease: Research and Practice. Stroke (2015) 0.78

Stroke and TIA survivors' cognitive beliefs and affective responses regarding treatment and future stroke risk differentially predict medication adherence and categorised stroke risk. Psychol Health (2014) 0.78

Association of cerebral white matter lesions with cognitive function and mood in Japanese elderly people: a population-based study. Brain Behav (2015) 0.77

Ischemic stroke: a cardiovascular risk equivalent? Lessons learned from the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) trial. Can J Cardiol (2008) 0.77

Inverse relationship between apolipoprotein A-I and cerebral white matter lesions: a cross-sectional study in middle-aged and elderly subjects. PLoS One (2014) 0.77

Effect of lipid profile upon prognosis in ischemic and haemorrhagic cerebrovascular stroke. Indian J Clin Biochem (2013) 0.76

Lipid profiles and ischemic stroke risk: variations by sex within racial/ethnic groups. Int J Womens Health (2014) 0.76

Cholesterol as a Risk Factor for Subarachnoid Hemorrhage: A Systematic Review. PLoS One (2016) 0.75

Synergistic effects of elevated homocysteine level and abnormal blood lipids on the onset of stroke. Neural Regen Res (2013) 0.75

Association between Low-density lipoprotein cholesterol and occipital periventricular hyperintensities in a group of Chinese patients: an observational study. Lipids Health Dis (2017) 0.75

Trends in the treatment of risk factors for stroke in a Czech stroke unit. Open Med (Wars) (2015) 0.75

Sex differences in outcomes after stroke among patients with low total cholesterol levels: a large hospital-based prospective study. Biol Sex Differ (2016) 0.75

Inverse association of plasma level of high-density lipoprotein cholesterol with intracerebral hemorrhage. J Lipid Res (2011) 0.75

Statin use after intracerebral hemorrhage: a 10-year nationwide cohort study. Brain Behav (2016) 0.75

Relation of Paraoxonase1, Arylesterase and Lipid Profile in Ischemic Stroke Patients. J Clin Diagn Res (2015) 0.75

Cerebral Amyloid Angiopathy in Stroke Medicine. Dtsch Arztebl Int (2017) 0.75

Articles by these authors

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25

Surveillance and ascertainment of cardiovascular events. The Cardiovascular Health Study. Ann Epidemiol (1995) 10.26

Genome-wide analysis of genetic loci associated with Alzheimer disease. JAMA (2010) 9.52

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. Nat Genet (2013) 9.46

Nifedipine. Dose-related increase in mortality in patients with coronary heart disease. Circulation (1995) 9.13

Assessing the sensitivity of regression results to unmeasured confounders in observational studies. Biometrics (1998) 8.48

The risk of myocardial infarction associated with antihypertensive drug therapies. JAMA (1995) 7.31

Childhood and adult socioeconomic status as predictors of mortality in Finland. Lancet (1994) 6.02

Post-cardiac arrest syndrome: epidemiology, pathophysiology, treatment, and prognostication. A consensus statement from the International Liaison Committee on Resuscitation (American Heart Association, Australian and New Zealand Council on Resuscitation, European Resuscitation Council, Heart and Stroke Foundation of Canada, InterAmerican Heart Foundation, Resuscitation Council of Asia, and the Resuscitation Council of Southern Africa); the American Heart Association Emergency Cardiovascular Care Committee; the Council on Cardiovascular Surgery and Anesthesia; the Council on Cardiopulmonary, Perioperative, and Critical Care; the Council on Clinical Cardiology; and the Stroke Council. Circulation (2008) 5.97

Health outcomes associated with antihypertensive therapies used as first-line agents. A systematic review and meta-analysis. JAMA (1997) 5.91

Validating administrative data in stroke research. Stroke (2002) 5.90

Plasma fibrinogen level and the risk of major cardiovascular diseases and nonvascular mortality: an individual participant meta-analysis. JAMA (2005) 5.60

Health outcomes associated with calcium antagonists compared with other first-line antihypertensive therapies: a meta-analysis of randomised controlled trials. Lancet (2000) 5.42

Genomewide association studies of stroke. N Engl J Med (2009) 5.29

The messenger under attack -- intimidation of researchers by special-interest groups. N Engl J Med (1997) 5.14

Home use of automated external defibrillators for sudden cardiac arrest. N Engl J Med (2008) 4.64

Contributions of the history, physical examination, and laboratory investigation in making medical diagnoses. West J Med (1992) 4.62

Community-level comparisons between the grocery store environment and individual dietary practices. Prev Med (1991) 4.45

Use of sonography to evaluate carotid atherosclerosis in the elderly. The Cardiovascular Health Study. CHS Collaborative Research Group. Stroke (1991) 4.21

Prevalence of atrial fibrillation in elderly subjects (the Cardiovascular Health Study). Am J Cardiol (1994) 4.08

Incidental findings on brain magnetic resonance imaging: systematic review and meta-analysis. BMJ (2009) 3.91

The Emerging Risk Factors Collaboration: analysis of individual data on lipid, inflammatory and other markers in over 1.1 million participants in 104 prospective studies of cardiovascular diseases. Eur J Epidemiol (2007) 3.81

Cognitive impairment and decline are associated with carotid artery disease in patients without clinically evident cerebrovascular disease. Ann Intern Med (2004) 3.66

Diabetes in older adults: comparison of 1997 American Diabetes Association classification of diabetes mellitus with 1985 WHO classification. Lancet (1998) 3.61

Are drugs within a class interchangeable? Lancet (1999) 3.58

JNC VI: timing is everything. Lancet (1997) 3.48

The clinical efficacy of magnetic resonance imaging in neuroimaging. Ann Intern Med (1994) 3.33

Increased risk of hip fracture among patients with end-stage renal disease. Kidney Int (2000) 3.29

Time to act on drug safety. JAMA (1998) 3.22

Prognosis in amyotrophic lateral sclerosis: a population-based study. Neurology (2003) 3.14

Withdrawal of support in intracerebral hemorrhage may lead to self-fulfilling prophecies. Neurology (2001) 3.07

Diuretic therapy for hypertension and the risk of primary cardiac arrest. N Engl J Med (1994) 3.04

The association of antihypertensive agents with MRI white matter findings and with Modified Mini-Mental State Examination in older adults. J Am Geriatr Soc (1997) 2.98

Serum potassium level and dietary potassium intake as risk factors for stroke. Neurology (2002) 2.98

Aspartame ingestion and headaches: a randomized crossover trial. Neurology (1994) 2.91

British guidelines on managing hypertension. Provide evidence, progress, and an occasional missed opportunity. BMJ (1999) 2.83

Midlife and late-life obesity and the risk of dementia: cardiovascular health study. Arch Neurol (2009) 2.79

Relationship of C-reactive protein to risk of cardiovascular disease in the elderly. Results from the Cardiovascular Health Study and the Rural Health Promotion Project. Arterioscler Thromb Vasc Biol (1997) 2.76

Neighborhood socioeconomic disadvantage and mortality after stroke. Neurology (2013) 2.74

Subclinical disease as an independent risk factor for cardiovascular disease. Circulation (1995) 2.71

Post-cardiac arrest syndrome: epidemiology, pathophysiology, treatment, and prognostication. A Scientific Statement from the International Liaison Committee on Resuscitation; the American Heart Association Emergency Cardiovascular Care Committee; the Council on Cardiovascular Surgery and Anesthesia; the Council on Cardiopulmonary, Perioperative, and Critical Care; the Council on Clinical Cardiology; the Council on Stroke. Resuscitation (2008) 2.63

Silent MRI infarcts and the risk of future stroke: the cardiovascular health study. Neurology (2001) 2.55

White matter hyperintensity on cranial magnetic resonance imaging: a predictor of stroke. Stroke (2004) 2.50

The relation of markers of inflammation to the development of glucose disorders in the elderly: the Cardiovascular Health Study. Diabetes (2001) 2.47

Inflammation and hemostasis biomarkers and cardiovascular risk in the elderly: the Cardiovascular Health Study. J Thromb Haemost (2007) 2.40

Differences in sociodemographic, health status, and lifestyle characteristics among American Indians by telephone coverage. Prev Med (1994) 2.37

Genome-wide association studies of cerebral white matter lesion burden: the CHARGE consortium. Ann Neurol (2011) 2.37

Elevated risk of stroke among patients with end-stage renal disease. Kidney Int (2003) 2.35

The association between cholesterol and death from injury. Ann Intern Med (1994) 2.26

Family history as a risk factor for primary cardiac arrest. Circulation (1998) 2.25

Antihypertensive drug therapies and the risk of ischemic stroke. Arch Intern Med (2001) 2.24

Therapeutic benefits of ACE inhibitors and other antihypertensive drugs in patients with type 2 diabetes. Diabetes Care (2000) 2.22

Surrogate end points, health outcomes, and the drug-approval process for the treatment of risk factors for cardiovascular disease. JAMA (1999) 2.21

Pilot randomized clinical trial of prehospital induction of mild hypothermia in out-of-hospital cardiac arrest patients with a rapid infusion of 4 degrees C normal saline. Circulation (2007) 2.18

Treatment of hypertensive patients with diabetes. Lancet (1998) 2.16

Factor V Leiden (resistance to activated protein C) increases the risk of myocardial infarction in young women. Blood (1997) 2.15

Fibrinolytic activation markers predict myocardial infarction in the elderly. The Cardiovascular Health Study. Arterioscler Thromb Vasc Biol (1999) 2.15

Sulcal, ventricular, and white matter changes at MR imaging in the aging brain: data from the cardiovascular health study. Radiology (1997) 2.13

Nicotine from edible Solanaceae and risk of Parkinson disease. Ann Neurol (2013) 2.08

The unnecessary controversy. Eur Heart J (1996) 2.05

Trends in pharmacologic management of hypertension in the United States. Arch Intern Med (1995) 2.04

Prospective study of alcohol consumption and risk of dementia in older adults. JAMA (2003) 1.98

Parkinson's disease risks associated with cigarette smoking, alcohol consumption, and caffeine intake. Am J Epidemiol (2002) 1.97

Alcohol use and risk of ischemic stroke among older adults: the cardiovascular health study. Stroke (2005) 1.94

Lifetime smoking exposure affects the association of C-reactive protein with cardiovascular disease risk factors and subclinical disease in healthy elderly subjects. Arterioscler Thromb Vasc Biol (1997) 1.90

Major electrocardiographic abnormalities in persons aged 65 years and older (the Cardiovascular Health Study). Cardiovascular Health Study Collaborative Research Group. Am J Cardiol (1992) 1.89

NSAID use and dementia risk in the Cardiovascular Health Study: role of APOE and NSAID type. Neurology (2007) 1.88

White matter grade and ventricular volume on brain MRI as markers of longevity in the cardiovascular health study. Neurobiol Aging (2006) 1.88

Cystatin C and subclinical brain infarction. J Am Soc Nephrol (2005) 1.88

The medical cost of undiagnosed sleep apnea. Sleep (1999) 1.86

HMG CoA reductase inhibitors and the risk of venous thrombosis among postmenopausal women. J Thromb Haemost (2004) 1.85

Risk factors for intracerebral hemorrhage in a pooled prospective study. Stroke (2007) 1.84

Common variants at 6p21.1 are associated with large artery atherosclerotic stroke. Nat Genet (2012) 1.81

Common variants at 12q14 and 12q24 are associated with hippocampal volume. Nat Genet (2012) 1.79

Hypertension and its treatment in postmenopausal women: baseline data from the Women's Health Initiative. Hypertension (2000) 1.77

Cardiovascular disease mortality in familial forms of hypertriglyceridemia: A 20-year prospective study. Circulation (2000) 1.76

Vascular events, mortality, and preventive therapy following ischemic stroke in the elderly. Neurology (2005) 1.76

Gait variability is associated with subclinical brain vascular abnormalities in high-functioning older adults. Neuroepidemiology (2007) 1.74

Occupational exposures and amyotrophic lateral sclerosis. A population-based case-control study. Am J Epidemiol (1997) 1.73

Atrial fibrillation and cognitive decline: a longitudinal cohort study. Neurology (2013) 1.71