Published in Diabetes on December 01, 2004
The unique cytoarchitecture of human pancreatic islets has implications for islet cell function. Proc Natl Acad Sci U S A (2006) 5.41
Human mesenchymal stem cells protect human islets from pro-inflammatory cytokines. PLoS One (2012) 1.76
A practical guide to rodent islet isolation and assessment. Biol Proced Online (2009) 1.74
Correlation between beta cell mass and glycemic control in type 1 diabetic recipients of islet cell graft. Proc Natl Acad Sci U S A (2006) 1.60
TLR agonists abrogate costimulation blockade-induced prolongation of skin allografts. J Immunol (2006) 1.57
Quantitative analysis of cell composition and purity of human pancreatic islet preparations. Lab Invest (2010) 1.43
Islet assessment for transplantation. Curr Opin Organ Transplant (2009) 1.36
Myeloid-derived suppressor cells protect islet transplants by B7-H1 mediated enhancement of T regulatory cells. Transplantation (2012) 1.09
Ischaemia is linked to inflammation and induction of angiogenesis in pancreatic islets. Clin Exp Immunol (2006) 1.07
Revascularization of transplanted pancreatic islets and role of the transplantation site. Clin Dev Immunol (2013) 1.04
Stem cells as a therapeutic target for diabetes. Front Biosci (Landmark Ed) (2010) 0.96
A simplified approach to human islet quality assessment. Transplantation (2010) 0.95
Rational bioprocess design for human pluripotent stem cell expansion and endoderm differentiation based on cellular dynamics. Biotechnol Bioeng (2011) 0.92
Quantitative assessment of islets of Langerhans encapsulated in alginate. Tissue Eng Part C Methods (2011) 0.89
Islet cell transplantation. Postgrad Med J (2007) 0.88
Characterization of pancreatic ductal cells in human islet preparations. Lab Invest (2008) 0.87
Prolactin supplementation to culture medium improves beta-cell survival. Transplantation (2010) 0.87
Human islet preparations distributed for research exhibit a variety of insulin-secretory profiles. Am J Physiol Endocrinol Metab (2015) 0.86
Immune responses against islet allografts during tapering of immunosuppression--a pilot study in 5 subjects. Clin Exp Immunol (2012) 0.86
RGD peptide-modified adenovirus expressing hepatocyte growth factor and X-linked inhibitor of apoptosis improves islet transplantation. J Gene Med (2011) 0.85
The quest for tissue stem cells in the pancreas and other organs, and their application in beta-cell replacement. Rev Diabet Stud (2010) 0.84
XIAP gene expression protects β-cells and human islets from apoptotic cell death. Mol Pharm (2010) 0.83
Pancreatic stem/progenitor cells for the treatment of diabetes. Rev Diabet Stud (2010) 0.83
Enumeration of islets by nuclei counting and light microscopic analysis. Lab Invest (2010) 0.81
Neurogenin 3 Expressing Cells in the Human Exocrine Pancreas Have the Capacity for Endocrine Cell Fate. PLoS One (2015) 0.81
Bioengineering a highly vascularized matrix for the ectopic transplantation of islets. Islets (2013) 0.80
Role of microRNAs in islet beta-cell compensation and failure during diabetes. J Diabetes Res (2014) 0.80
The isolated pancreatic islet as a micro-organ and its transplantation to cure diabetes: celebrating the legacy of Paul Lacy. Islets (2010) 0.79
Quantitative assessment of β-cell apoptosis and cell composition of isolated, undisrupted human islets by laser scanning cytometry. Transplantation (2010) 0.79
Recent advances in stem cell research for the treatment of diabetes. World J Stem Cells (2009) 0.79
Plasma GAD65, a Marker for Early β-Cell Loss After Intraportal Islet Cell Transplantation in Diabetic Patients. J Clin Endocrinol Metab (2015) 0.79
Induction of tissue-specific stem cells by reprogramming factors, and tissue-specific selection. Cell Death Differ (2014) 0.78
Isolation and characterization of islet stellate cells in rat. Islets (2014) 0.78
Positive correlation of PTH-related peptide with glucose in type 2 diabetes. Exp Diabetes Res (2009) 0.77
Pancreatic β Cell Mass Death. Front Pharmacol (2016) 0.77
3-D Imaging Reveals Participation of Donor Islet Schwann Cells and Pericytes in Islet Transplantation and Graft Neurovascular Regeneration. EBioMedicine (2015) 0.77
Islet oxygen consumption rate dose predicts insulin independence for first clinical islet allotransplants. Transplant Proc (2014) 0.77
Label-free detection of insulin and glucagon within human islets of Langerhans using Raman spectroscopy. PLoS One (2013) 0.77
Implication of mitochondrial cytoprotection in human islet isolation and transplantation. Biochem Res Int (2012) 0.77
Continuous glucose monitoring analysis as predictor of islet yield and insulin requirements in autologous islet transplantation after complete pancreatectomy. J Diabetes Sci Technol (2014) 0.77
Filtration is a time-efficient option to Histopaque, providing good-quality islets in mouse islet isolation. Cytotechnology (2014) 0.76
Bioengineering the Endocrine Pancreas: Intraomental Islet Transplantation Within a Biologic Resorbable Scaffold. Diabetes (2016) 0.76
Islet preparation purity is overestimated, and less pure fractions have lower post-culture viability before clinical allotransplantation. Transplant Proc (2014) 0.76
Development and Characterization of a Collagen-Based Matrix for Vascularization and Cell Delivery. Biores Open Access (2015) 0.75
Enumerating β-Cells in Whole Human Islets: Sex Differences and Associations With Clinical Outcomes After Islet Transplantation. Diabetes Care (2015) 0.75
Regulation of the JNK3 signaling pathway during islet isolation: JNK3 and c-fos as new markers of islet quality for transplantation. PLoS One (2014) 0.75
Culture Conditions for Mouse Pancreatic Stem Cells. Cell Med (2013) 0.75
Isolation Efficiency of Mouse Pancreatic Stem Cells Is Age Dependent. Cell Med (2013) 0.75
3-D imaging of islets in obesity: formation of the islet-duct complex and neurovascular remodeling in young hyperphagic mice. Int J Obes (Lond) (2015) 0.75
Quality of Air-Transported Human Islets for Single Islet Cell Preparations. Cell Med (2013) 0.75
β-Cell regeneration through the transdifferentiation of pancreatic cells: Pancreatic progenitor cells in the pancreas. J Diabetes Investig (2016) 0.75
International trial of the Edmonton protocol for islet transplantation. N Engl J Med (2006) 13.43
Five-year follow-up after clinical islet transplantation. Diabetes (2005) 7.86
Silicene: compelling experimental evidence for graphenelike two-dimensional silicon. Phys Rev Lett (2012) 3.87
Sirolimus-based immunosuppression is associated with increased survival after liver transplantation for hepatocellular carcinoma. Hepatology (2010) 3.54
The Canadian Trial of Carbohydrates in Diabetes (CCD), a 1-y controlled trial of low-glycemic-index dietary carbohydrate in type 2 diabetes: no effect on glycated hemoglobin but reduction in C-reactive protein. Am J Clin Nutr (2008) 3.33
Improvement in outcomes of clinical islet transplantation: 1999-2010. Diabetes Care (2012) 3.20
Reassessing selection criteria prior to liver transplantation for hepatocellular carcinoma utilizing the Scientific Registry of Transplant Recipients database. Hepatology (2009) 2.51
Short-term intensive insulin therapy in newly diagnosed type 2 diabetes. Diabetes Care (2004) 2.46
Beta-cell differentiation from nonendocrine epithelial cells of the adult human pancreas. Nat Med (2006) 2.41
Gestational diabetes: new criteria may triple the prevalence but effect on outcomes is unclear. BMJ (2014) 2.40
Successful islet transplantation: continued insulin reserve provides long-term glycemic control. Diabetes (2002) 2.36
Inhibition of Th17 cells regulates autoimmune diabetes in NOD mice. Diabetes (2009) 2.31
Assessment of the severity of hypoglycemia and glycemic lability in type 1 diabetic subjects undergoing islet transplantation. Diabetes (2004) 2.22
Long-term survival of neonatal porcine islets in nonhuman primates by targeting costimulation pathways. Nat Med (2006) 2.21
Cell encapsulation: promise and progress. Nat Med (2003) 2.18
A human beta-cell line for transplantation therapy to control type 1 diabetes. Nat Biotechnol (2005) 2.12
Total tumor volume predicts risk of recurrence following liver transplantation in patients with hepatocellular carcinoma. Liver Transpl (2008) 2.04
Glutaraldehyde-fixed bioprosthetic heart valve conduits calcify and fail from xenograft rejection. Circulation (2006) 1.89
Sirolimus-based immunosuppression for liver transplantation in the presence of extended criteria for hepatocellular carcinoma. Liver Transpl (2004) 1.80
Changes in renal function after clinical islet transplantation: four-year observational study. Am J Transplant (2007) 1.78
Human mesenchymal stem cells protect human islets from pro-inflammatory cytokines. PLoS One (2012) 1.76
Combination therapy with sirolimus and interleukin-2 prevents spontaneous and recurrent autoimmune diabetes in NOD mice. Diabetes (2002) 1.61
Combination therapy with epidermal growth factor and gastrin induces neogenesis of human islet {beta}-cells from pancreatic duct cells and an increase in functional {beta}-cell mass. J Clin Endocrinol Metab (2005) 1.61
Granzyme B: a natural born killer. Immunol Rev (2003) 1.61
Liraglutide, a long-acting human glucagon-like peptide 1 analogue, improves human islet survival in culture. Transpl Int (2009) 1.58
Spiral enteroscopy: a novel method of enteroscopy by using the Endo-Ease Discovery SB overtube and a pediatric colonoscope. Gastrointest Endosc (2008) 1.58
BTLA targeting modulates lymphocyte phenotype, function, and numbers and attenuates disease in nonobese diabetic mice. J Leukoc Biol (2009) 1.53
Loss of TGH/Ces3 in mice decreases blood lipids, improves glucose tolerance, and increases energy expenditure. Cell Metab (2010) 1.49
Prevalence of hepatic steatosis after islet transplantation and its relation to graft function. Diabetes (2004) 1.46
Edmonton's islet success has indeed been replicated elsewhere. Lancet (2003) 1.45
Diabetes Is Reversed in a Murine Model by Marginal Mass Syngeneic Islet Transplantation Using a Subcutaneous Cell Pouch Device. Transplantation (2015) 1.44
A novel approach to increase human islet cell mass while preserving beta-cell function. Diabetes (2002) 1.43
Update on islet transplantation. Cold Spring Harb Perspect Med (2012) 1.40
Beta-score: an assessment of beta-cell function after islet transplantation. Diabetes Care (2005) 1.35
Percutaneous transhepatic pancreatic islet cell transplantation in type 1 diabetes mellitus: radiologic aspects. Radiology (2003) 1.34
Strategic opportunities in clinical islet transplantation. Transplantation (2005) 1.34
Intrahepatic islet transplantation in type 1 diabetic patients does not restore hypoglycemic hormonal counterregulation or symptom recognition after insulin independence. Diabetes (2002) 1.32
Expansion of mesenchymal stem cells from human pancreatic ductal epithelium. Lab Invest (2006) 1.28
Factors influencing the loss of beta-cell mass in islet transplantation. Cell Transplant (2007) 1.27
Survival and metabolic function of syngeneic rat islet grafts transplanted in the omental pouch. Am J Transplant (2003) 1.26
Current status of clinical islet cell transplantation. Methods Mol Biol (2006) 1.25
Portal venous pressure changes after sequential clinical islet transplantation. Transplantation (2002) 1.24
Metformin, but not leptin, regulates AMP-activated protein kinase in pancreatic islets: impact on glucose-stimulated insulin secretion. Am J Physiol Endocrinol Metab (2004) 1.23
Prevention of bleeding after islet transplantation: lessons learned from a multivariate analysis of 132 cases at a single institution. Am J Transplant (2005) 1.23
Interventional strategies to prevent beta-cell apoptosis in islet transplantation. Diabetes (2006) 1.21
Toward development of imaging modalities for islets after transplantation: insights from the National Institutes of Health Workshop on Beta Cell Imaging. Transplantation (2004) 1.17
Combination therapy with glucagon-like peptide-1 and gastrin induces beta-cell neogenesis from pancreatic duct cells in human islets transplanted in immunodeficient diabetic mice. Cell Transplant (2008) 1.16
Enhancing the success of human islet isolation through optimization and characterization of pancreas dissociation enzyme. Am J Transplant (2007) 1.14
The portal immunosuppressive storm: relevance to islet transplantation? Ther Drug Monit (2005) 1.14
Estimation of pancreas weight from donor variables. Cell Transplant (2006) 1.13
Synaptosome-associated protein of 25 kilodaltons modulates Kv2.1 voltage-dependent K(+) channels in neuroendocrine islet beta-cells through an interaction with the channel N terminus. Mol Endocrinol (2002) 1.13
Islet isolation and transplantation outcomes of pancreas preserved with University of Wisconsin solution versus two-layer method using preoxygenated perfluorocarbon. Transplantation (2006) 1.12
Functional MR microimaging of pancreatic beta-cell activation. Cell Transplant (2006) 1.12
Histologic graft assessment after clinical islet transplantation. Transplantation (2009) 1.12
XIAP overexpression in human islets prevents early posttransplant apoptosis and reduces the islet mass needed to treat diabetes. Diabetes (2005) 1.12
De novo sirolimus-based immunosuppression after liver transplantation for hepatocellular carcinoma: long-term outcomes and side effects. Transplantation (2007) 1.11
Current status of pancreatic islet transplantation. Clin Sci (Lond) (2006) 1.11
Glucose regulates cyclin D2 expression in quiescent and replicating pancreatic β-cells through glycolysis and calcium channels. Endocrinology (2011) 1.11
Insulin-heparin infusions peritransplant substantially improve single-donor clinical islet transplant success. Transplantation (2010) 1.10
Advances in pancreatic islet transplantation in humans. Diabetes Obes Metab (2006) 1.08