Published in Methods Mol Biol on January 01, 2006
Generation of pluripotent stem cells from patients with type 1 diabetes. Proc Natl Acad Sci U S A (2009) 3.43
Reprogrammed Stomach Tissue as a Renewable Source of Functional β Cells for Blood Glucose Regulation. Cell Stem Cell (2016) 2.10
Reversal of hyperglycemia in diabetic mouse models using induced-pluripotent stem (iPS)-derived pancreatic beta-like cells. Proc Natl Acad Sci U S A (2010) 1.67
Vaccination against type 1 diabetes. J Intern Med (2011) 1.46
Stem cell therapy for type 1 diabetes mellitus. Nat Rev Endocrinol (2010) 1.21
Interleukin (IL)-10 induced by CD11b(+) cells and IL-10-activated regulatory T cells play a role in immune modulation of mesenchymal stem cells in rat islet allografts. Mol Med (2011) 1.17
Vasculogenic bio-synthetic hydrogel for enhancement of pancreatic islet engraftment and function in type 1 diabetes. Biomaterials (2013) 1.07
Suppression of KATP channel activity protects murine pancreatic beta cells against oxidative stress. J Clin Invest (2009) 1.00
Allogeneic bone marrow supports human islet beta cell survival and function over six months. Biochem Biophys Res Commun (2007) 0.95
Preparatory studies of composite mesenchymal stem cell islets for application in intraportal islet transplantation. Ups J Med Sci (2010) 0.93
Human BM stem cells initiate angiogenesis in human islets in vitro. Bone Marrow Transplant (2010) 0.92
Immunoglobulin-like transcript 3-Fc suppresses T-cell responses to allogeneic human islet transplants in hu-NOD/SCID mice. Diabetes (2008) 0.92
Differentiation and transplantation of functional pancreatic beta cells generated from induced pluripotent stem cells derived from a type 1 diabetes mouse model. Stem Cells Dev (2012) 0.90
Switching-on survival and repair response programs in islet transplants by bone marrow-derived vasculogenic cells. Diabetes (2008) 0.86
Reversal of diabetes in mice by intrahepatic injection of bone-derived GFP-murine mesenchymal stem cells infected with the recombinant retrovirus-carrying human insulin gene. World J Surg (2007) 0.85
Engineered VEGF-releasing PEG-MAL hydrogel for pancreatic islet vascularization. Drug Deliv Transl Res (2015) 0.82
Oleanolic Acid, a plant triterpenoid, significantly improves survival and function of islet allograft. Transplantation (2009) 0.81
Reprogramming adult human dermal fibroblasts to islet-like cells by epigenetic modification coupled to transcription factor modulation. Stem Cells Dev (2013) 0.80
PEG-maleimide hydrogels for protein and cell delivery in regenerative medicine. Ann Biomed Eng (2013) 0.79
Simplified method to isolate highly pure canine pancreatic islets. Pancreas (2012) 0.78
CD4+ T cells are sufficient to elicit allograft rejection and major histocompatibility complex class I molecule is required to induce recurrent autoimmune diabetes after pancreas transplantation in mice. Transplantation (2008) 0.77
Evaluation of fetal cell transplantation safety in treatment of diabetes: a three-year follow-up. J Diabetes Metab Disord (2015) 0.75
Five-year follow-up after clinical islet transplantation. Diabetes (2005) 7.86
Sirolimus-based immunosuppression is associated with increased survival after liver transplantation for hepatocellular carcinoma. Hepatology (2010) 3.54
Improvement in outcomes of clinical islet transplantation: 1999-2010. Diabetes Care (2012) 3.20
Reassessing selection criteria prior to liver transplantation for hepatocellular carcinoma utilizing the Scientific Registry of Transplant Recipients database. Hepatology (2009) 2.51
Successful islet transplantation: continued insulin reserve provides long-term glycemic control. Diabetes (2002) 2.36
Inhibition of Th17 cells regulates autoimmune diabetes in NOD mice. Diabetes (2009) 2.31
Assessment of the severity of hypoglycemia and glycemic lability in type 1 diabetic subjects undergoing islet transplantation. Diabetes (2004) 2.22
Cell encapsulation: promise and progress. Nat Med (2003) 2.18
Total tumor volume predicts risk of recurrence following liver transplantation in patients with hepatocellular carcinoma. Liver Transpl (2008) 2.04
Islet graft assessment in the Edmonton Protocol: implications for predicting long-term clinical outcome. Diabetes (2004) 1.98
Sirolimus-based immunosuppression for liver transplantation in the presence of extended criteria for hepatocellular carcinoma. Liver Transpl (2004) 1.80
Changes in renal function after clinical islet transplantation: four-year observational study. Am J Transplant (2007) 1.78
Human mesenchymal stem cells protect human islets from pro-inflammatory cytokines. PLoS One (2012) 1.76
Combination therapy with sirolimus and interleukin-2 prevents spontaneous and recurrent autoimmune diabetes in NOD mice. Diabetes (2002) 1.61
Liraglutide, a long-acting human glucagon-like peptide 1 analogue, improves human islet survival in culture. Transpl Int (2009) 1.58
BTLA targeting modulates lymphocyte phenotype, function, and numbers and attenuates disease in nonobese diabetic mice. J Leukoc Biol (2009) 1.53
Prevalence of hepatic steatosis after islet transplantation and its relation to graft function. Diabetes (2004) 1.46
Edmonton's islet success has indeed been replicated elsewhere. Lancet (2003) 1.45
Diabetes Is Reversed in a Murine Model by Marginal Mass Syngeneic Islet Transplantation Using a Subcutaneous Cell Pouch Device. Transplantation (2015) 1.44
Update on islet transplantation. Cold Spring Harb Perspect Med (2012) 1.40
Beta-score: an assessment of beta-cell function after islet transplantation. Diabetes Care (2005) 1.35
Percutaneous transhepatic pancreatic islet cell transplantation in type 1 diabetes mellitus: radiologic aspects. Radiology (2003) 1.34
Intrahepatic islet transplantation in type 1 diabetic patients does not restore hypoglycemic hormonal counterregulation or symptom recognition after insulin independence. Diabetes (2002) 1.32
Factors influencing the loss of beta-cell mass in islet transplantation. Cell Transplant (2007) 1.27
Cardiovascular risk factors in the elderly: the Tehran Lipid and Glucose Study. J Cardiovasc Risk (2003) 1.23
Prevention of bleeding after islet transplantation: lessons learned from a multivariate analysis of 132 cases at a single institution. Am J Transplant (2005) 1.23
Interventional strategies to prevent beta-cell apoptosis in islet transplantation. Diabetes (2006) 1.21
Toward development of imaging modalities for islets after transplantation: insights from the National Institutes of Health Workshop on Beta Cell Imaging. Transplantation (2004) 1.17
Enhancing the success of human islet isolation through optimization and characterization of pancreas dissociation enzyme. Am J Transplant (2007) 1.14
Estimation of pancreas weight from donor variables. Cell Transplant (2006) 1.13
Islet isolation and transplantation outcomes of pancreas preserved with University of Wisconsin solution versus two-layer method using preoxygenated perfluorocarbon. Transplantation (2006) 1.12
Histologic graft assessment after clinical islet transplantation. Transplantation (2009) 1.12
XIAP overexpression in human islets prevents early posttransplant apoptosis and reduces the islet mass needed to treat diabetes. Diabetes (2005) 1.12
De novo sirolimus-based immunosuppression after liver transplantation for hepatocellular carcinoma: long-term outcomes and side effects. Transplantation (2007) 1.11
Glucose regulates cyclin D2 expression in quiescent and replicating pancreatic β-cells through glycolysis and calcium channels. Endocrinology (2011) 1.11
Current status of pancreatic islet transplantation. Clin Sci (Lond) (2006) 1.11
Insulin-heparin infusions peritransplant substantially improve single-donor clinical islet transplant success. Transplantation (2010) 1.10
Advances in pancreatic islet transplantation in humans. Diabetes Obes Metab (2006) 1.08
Assessment of glycemic control after islet transplantation using the continuous glucose monitor in insulin-independent versus insulin-requiring type 1 diabetes subjects. Diabetes Technol Ther (2006) 1.08
Comparison of human islet isolation outcomes using a new mammalian tissue-free enzyme versus collagenase NB-1. Transplantation (2010) 1.06
Costimulation blockade of both inducible costimulator and CD40 ligand induces dominant tolerance to islet allografts and prevents spontaneous autoimmune diabetes in the NOD mouse. Diabetes (2006) 1.05
Revascularization of transplanted pancreatic islets and role of the transplantation site. Clin Dev Immunol (2013) 1.04
Factors influencing the collagenase digestion phase of human islet isolation. Transplantation (2007) 1.03
Surgical aspects of human islet isolation. Islets (2010) 1.03
Circumportal pancreas and islet isolation. Surgery (2008) 1.03
Islet transplantation in patients with diabetes mellitus: choice of immunosuppression. BioDrugs (2004) 1.01
Multiple combination therapies involving blockade of ICOS/B7RP-1 costimulation facilitate long-term islet allograft survival. Am J Transplant (2004) 1.00
Effect of different induction strategies on effector, regulatory and memory lymphocyte sub-populations in clinical islet transplantation. Transpl Int (2008) 1.00
Risks and side effects of islet transplantation. Curr Diab Rep (2004) 1.00
Beta-cell transplantation for diabetes therapy. Lancet (2008) 0.99
Technical aspects of islet preparation and transplantation. Transpl Int (2003) 0.98
Current indications for pancreas or islet transplant. Diabetes Obes Metab (2006) 0.98
Quality of life after islet transplant: impact of the number of islet infusions and metabolic outcome. Transplantation (2007) 0.98
Caspase inhibitor therapy enhances marginal mass islet graft survival and preserves long-term function in islet transplantation. Diabetes (2007) 0.97
Role of imaging in clinical islet transplantation. Radiographics (2010) 0.95
Vascular endothelial growth factor expression in hepatic epithelioid hemangioendothelioma: Implications for treatment and surgical management. Liver Transpl (2010) 0.95
Porcine marginal mass islet autografts resist metabolic failure over time and are enhanced by early treatment with liraglutide. Endocrinology (2009) 0.95
Development of either split tolerance or robust tolerance along with humoral tolerance to donor and third-party alloantigens in nonmyeloablative mixed chimeras. J Immunol (2008) 0.95
The caspase selective inhibitor EP1013 augments human islet graft function and longevity in marginal mass islet transplantation in mice. Diabetes (2008) 0.95
Supplemental islet infusions restore insulin independence after graft dysfunction in islet transplant recipients. Transplantation (2010) 0.94
Unraveling the secrets of single donor success in islet transplantation. Am J Transplant (2004) 0.94
Pancreas divisum: a study of the cadaveric donor pancreas for islet isolation. Pancreas (2005) 0.94
High prevalence of ovarian cysts in premenopausal women receiving sirolimus and tacrolimus after clinical islet transplantation. Transpl Int (2009) 0.93
Effect of core pancreas temperature during cadaveric procurement on human islet isolation and functional viability. Transplantation (2002) 0.93
Neonatal porcine islets exhibit natural resistance to hypoxia-induced apoptosis. Transplantation (2006) 0.93
A comparison of islet autotransplantation with allotransplantation and factors elevating acute portal pressure in clinical islet transplantation. J Hepatobiliary Pancreat Sci (2012) 0.93
Histopaque provides optimal mouse islet purification kinetics: comparison study with Ficoll, iodixanol and dextran. Islets (2011) 0.92
Changes in liver enzymes after clinical islet transplantation. Transplantation (2003) 0.92
Coinhibitory T-cell signaling in islet allograft rejection and tolerance. Cell Transplant (2006) 0.92
Laparoscopic splenectomy for the treatment of refractory immune thrombocytopenia in pregnancy. J Obstet Gynaecol Can (2005) 0.91
Islet transplantation: progress and challenge. Arch Med Res (2005) 0.91
Detection of microbial contamination during human islet isolation. Cell Transplant (2007) 0.90
Impact of recipient age on outcome of ABO-incompatible living-donor liver transplantation. Transplantation (2004) 0.90
Islet transplants and impact on secondary diabetic complications: does C-Peptide protect the kidney? J Am Soc Nephrol (2003) 0.90
Influence of pancreas preservation on human islet isolation outcomes: impact of the two-layer method. Transplantation (2004) 0.90
Experience of islet isolation without neutral protease supplementation. Islets (2010) 0.90
Randomized controlled trial to investigate the impact of anticoagulation on the incidence of splenic or portal vein thrombosis after laparoscopic splenectomy. Can J Surg (2011) 0.90
Enriched human pancreatic ductal cultures obtained from selective death of acinar cells express pancreatic and duodenal homeobox gene-1 age-dependently. Rev Diabet Stud (2004) 0.90
Non-myeloablative mixed chimerism approaches and tolerance, a split decision. Eur J Immunol (2007) 0.88
Pancreatic islet autotransplantation with completion pancreatectomy in the management of uncontrolled pancreatic fistula after whipple resection for ampullary adenocarcinoma. Pancreas (2006) 0.87
Are stem cells a cure for diabetes? Clin Sci (Lond) (2009) 0.87
Nonsimultaneous administration of pancreas dissociation enzymes during islet isolation. Transplantation (2009) 0.87
Single-donor islet transplantation and long-term insulin independence in select patients with type 1 diabetes mellitus. Transplantation (2014) 0.87
Human islet transplantation from pancreases with prolonged cold ischemia using additional preservation by the two-layer (UW solution/perfluorochemical) cold-storage method. Transplantation (2002) 0.87
Sirolimus drug-eluting, hydrogel-impregnated polypropylene mesh reduces intra-abdominal adhesion formation in a mouse model. Surgery (2011) 0.86
Clinical islet transplantation at the University of Alberta--the Edmonton experience. Clin Transpl (2005) 0.86
Quantitative assessment of collagenase blends for human islet isolation. Transplantation (2005) 0.86
The caspase inhibitor IDN-6556 (PF3491390) improves marginal mass engraftment after islet transplantation in mice. Surgery (2011) 0.86
Robust tolerance to fully allogeneic islet transplants achieved by chimerism with minimal conditioning. Transplantation (2005) 0.86
Follow-up study of the first successful living donor islet transplantation. Transplantation (2006) 0.85
Preservation of the human pancreas before islet isolation using a two-layer (UW solution-perfluorochemical) cold storage method. Transplantation (2002) 0.85
Further evidence for amyloid deposition in clinical pancreatic islet grafts. Transplantation (2012) 0.85
An isolated venous sac as a novel site for cell therapy in diabetes mellitus. Transplantation (2012) 0.84
Functional plasticity of the human infant β-cell exocytotic phenotype. Endocrinology (2013) 0.84
Reduced fear of hypoglycemia in successful islet transplantation. Diabetes Care (2004) 0.84
Cross-sectional and prospective association between proinsulin secretion and graft function after clinical islet transplantation. Transplantation (2004) 0.82
The use of an approved biodegradable polymer scaffold as a solid support system for improvement of islet engraftment. Artif Organs (2008) 0.82
The role of macrophage migration inhibitory factor in mouse islet transplantation. Transplantation (2008) 0.82
Hepatic artery-portal venous fistula after percutaneous intraportal islet cell transplant. Transplantation (2007) 0.81