PubRank

K P Klugman

Author PubWeight™ 139.38‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Nomenclature of major antimicrobial-resistant clones of Streptococcus pneumoniae defined by the pneumococcal molecular epidemiology network. J Clin Microbiol 2001 6.66
2 Epidemiology of ciprofloxacin resistance and its relationship to extended-spectrum beta-lactamase production in Klebsiella pneumoniae isolates causing bacteremia. Clin Infect Dis 2000 4.24
3 Outcome of cephalosporin treatment for serious infections due to apparently susceptible organisms producing extended-spectrum beta-lactamases: implications for the clinical microbiology laboratory. J Clin Microbiol 2001 4.19
4 Immunogenicity and impact on nasopharyngeal carriage of a nonavalent pneumococcal conjugate vaccine. J Infect Dis 1999 3.72
5 Failure of chloramphenicol therapy in penicillin-resistant pneumococcal meningitis. Lancet 1992 3.42
6 Management of community-acquired pneumonia in the era of pneumococcal resistance: a report from the Drug-Resistant Streptococcus pneumoniae Therapeutic Working Group. Arch Intern Med 2000 3.09
7 Genetic diversity of penicillin-binding protein 2B and 2X genes from Streptococcus pneumoniae in South Africa. Antimicrob Agents Chemother 1993 2.44
8 Increased disease burden and antibiotic resistance of bacteria causing severe community-acquired lower respiratory tract infections in human immunodeficiency virus type 1-infected children. Clin Infect Dis 2000 2.02
9 Alterations in PBP 1A essential-for high-level penicillin resistance in Streptococcus pneumoniae. Antimicrob Agents Chemother 1998 1.98
10 Lack of utility of serotyping multiple colonies for detection of simultaneous nasopharyngeal carriage of different pneumococcal serotypes. Pediatr Infect Dis J 2000 1.87
11 Association of serotypes of Streptococcus pneumoniae with disease severity and outcome in adults: an international study. Clin Infect Dis 2007 1.87
12 Alterations in penicillin-binding protein 2B from penicillin-resistant wild-type strains of Streptococcus pneumoniae. Antimicrob Agents Chemother 1995 1.82
13 Spread of the Spanish multi-resistant serotype 23F clone of Streptococcus pneumoniae to Seoul, Korea. Microb Drug Resist 1997 1.74
14 Use of a rapid test of pneumococcal colonization density to diagnose pneumococcal pneumonia. Clin Infect Dis 2011 1.70
15 Impact of human immunodeficiency virus type 1 on the disease spectrum of Streptococcus pneumoniae in South African children. Pediatr Infect Dis J 2000 1.69
16 Evaluation of the Etest as a means of determining the antibiotic susceptibilities of isolates of Streptococcus pneumoniae and Haemophilus influenzae from children in the Central African Republic. J Antimicrob Chemother 2000 1.67
17 Mutations in the dihydrofolate reductase gene of trimethoprim-resistant isolates of Streptococcus pneumoniae. Antimicrob Agents Chemother 1997 1.66
18 Serotype 19f multiresistant pneumococcal clone harboring two erythromycin resistance determinants (erm(B) and mef(A)) in South Africa. Antimicrob Agents Chemother 2001 1.60
19 Clinical and nasopharyngeal isolates of unusual multiply resistant pneumococci. Am J Dis Child 1986 1.55
20 Increased burden of respiratory viral associated severe lower respiratory tract infections in children infected with human immunodeficiency virus type-1. J Pediatr 2000 1.54
21 Laboratory-based diagnosis of pneumococcal pneumonia: state of the art and unmet needs. Clin Microbiol Infect 2011 1.54
22 Efficacy of Vi polysaccharide vaccine against strains of Salmonella typhi: reply. Vaccine 1998 1.51
23 Antibiotic-resistant pneumococcal disease in South African children. Am J Dis Child 1992 1.49
24 'Atypical' bacteria are a common cause of community-acquired pneumonia in hospitalised adults. S Afr Med J 1994 1.46
25 Three predominant clones identified within penicillin-resistant South African isolates of Streptococcus pneumoniae. Microb Drug Resist 1997 1.45
26 Acquisition, carriage, and transmission of pneumococci with decreased antibiotic susceptibility in young children attending a day care facility in southern Israel. J Infect Dis 1998 1.42
27 In vitro activities of 14 antibiotics against 100 human isolates of Yersinia pestis from a southern African plague focus. Antimicrob Agents Chemother 1996 1.42
28 Alterations in MurM, a cell wall muropeptide branching enzyme, increase high-level penicillin and cephalosporin resistance in Streptococcus pneumoniae. Antimicrob Agents Chemother 2001 1.40
29 Increased carriage of trimethoprim/sulfamethoxazole-resistant Streptococcus pneumoniae in Malawian children after treatment for malaria with sulfadoxine/pyrimethamine. J Infect Dis 2000 1.33
30 Mutations in ribosomal protein L16 conferring reduced susceptibility to evernimicin (SCH27899): implications for mechanism of action. Antimicrob Agents Chemother 2000 1.32
31 Long-term survival of Streptococcus pneumoniae at room temperature on Dorset egg medium. J Clin Microbiol 1998 1.26
32 Rapid detection of penicillin-resistant Streptococcus pneumoniae in cerebrospinal fluid by a seminested-PCR strategy. J Clin Microbiol 1998 1.26
33 Non-Penicillin-Binding protein mediated high-level penicillin and cephalosporin resistance in a Hungarian clone of Streptococcus pneumoniae. Microb Drug Resist 2000 1.24
34 Molecular basis of rifampin resistance in Streptococcus pneumoniae. Antimicrob Agents Chemother 1999 1.24
35 Streptococcus pneumoniae blood culture isolates from patients with and without human immunodeficiency virus infection: alterations in penicillin susceptibilities and in serogroups or serotypes. Clin Infect Dis 1997 1.23
36 Carriage of penicillin resistant pneumococci. Arch Dis Child 1986 1.20
37 Evernimicin (SCH27899) inhibits a novel ribosome target site: analysis of 23S ribosomal DNA mutants. Antimicrob Agents Chemother 2000 1.19
38 Evidence to support the rationale that bacterial eradication in respiratory tract infection is an important aim of antimicrobial therapy. J Antimicrob Chemother 2001 1.18
39 "Megaprimer" method of PCR-based mutagenesis: the concentration of megaprimer is a critical factor. Biotechniques 1997 1.18
40 Emergence of the M phenotype of erythromycin-resistant pneumococci in South Africa. Emerg Infect Dis 1998 1.17
41 Identification of the tetracycline resistance gene, tet(O), in Streptococcus pneumoniae. Antimicrob Agents Chemother 1996 1.16
42 Antimicrobial resistance of nasopharyngeal isolates of Streptococcus pneumoniae and Haemophilus influenzae from children in the Central African Republic. Pediatr Infect Dis J 2000 1.10
43 Worldwide increase in pneumococcal antibiotic resistance. Lancet 1989 1.08
44 Urinary tract infection with Corynebacterium urealyticum in South Africa. Eur J Clin Microbiol Infect Dis 1993 1.07
45 Neonatal typhoid fever. Pediatr Infect Dis J 1994 1.07
46 Penetration of meropenem into the cerebrospinal fluid of patients with inflamed meninges. J Antimicrob Chemother 1994 1.07
47 Acquisition of chloramphenicol resistance by the linearization and integration of the entire staphylococcal plasmid pC194 into the chromosome of Streptococcus pneumoniae. Antimicrob Agents Chemother 2000 1.05
48 Persistence of antibodies to the Salmonella typhi Vi capsular polysaccharide vaccine in South African school children ten years after immunization. Vaccine 1999 1.04
49 Fluoroquinolone resistance in invasive Streptococcus pyogenes isolates due to spontaneous mutation and horizontal gene transfer. Antimicrob Agents Chemother 2006 1.04
50 Laboratory surveillance for Haemophilus influenzae type B meningococcal, and pneumococcal disease. Haemophilus Surveillance Working Group. S Afr Med J 1999 1.03
51 Trends in antimicrobial resistance and serotype distribution of blood and cerebrospinal fluid isolates of Streptococcus pneumoniae in South Africa, 1991-1998. Int J Infect Dis 2000 1.02
52 Comparison of the effects of macrolides, amoxicillin, ceftriaxone, doxycycline, tobramycin and fluoroquinolones, on the production of pneumolysin by Streptococcus pneumoniae in vitro. J Antimicrob Chemother 2007 1.01
53 Bacteremic pneumococcal pneumonia in HIV-seropositive and HIV-seronegative adults. Chest 1999 1.00
54 Wound colonization by Ewingella americana. J Clin Microbiol 1986 1.00
55 Prevalence of serotypes and molecular epidemiology of Streptococcus pneumoniae strains isolated from children in Beijing, China: identification of two novel multiply-resistant clones. Microb Drug Resist 2001 1.00
56 Impact of human immunodeficiency virus type 1 infection on the epidemiology and outcome of bacterial meningitis in South African children. Int J Infect Dis 2001 1.00
57 Colony morphology of piliated Neisseria meningitidis. J Exp Med 1989 0.98
58 Molecular mechanisms of resistance to commonly used non-betalactam drugs in Streptococcus pneumoniae. Semin Respir Infect 1999 0.97
59 New gene cassettes for trimethoprim resistance, dfr13, and Streptomycin-spectinomycin resistance, aadA4, inserted on a class 1 integron. Antimicrob Agents Chemother 2000 0.97
60 Fluoroquinolone-resistant Streptococcus pneumoniae, an emerging but unrecognized public health concern: is it time to resight the goalposts? Clin Infect Dis 2004 0.96
61 Novel expansions of the gene encoding dihydropteroate synthase in trimethoprim-sulfamethoxazole-resistant Streptococcus pneumoniae. Antimicrob Agents Chemother 1999 0.96
62 Severity of illness scoring systems in patients with bacteraemic pneumococcal pneumonia: implications for the intensive care unit care. Clin Microbiol Infect 2009 0.95
63 A century of pneumococcal vaccination research in humans. Clin Microbiol Infect 2012 0.95
64 Consensus: management of infections in children caused by Streptococcus pneumoniae with decreased susceptibility to penicillin. Pediatr Infect Dis J 1995 0.95
65 Prevalence of trimethoprim resistant dihydrofolate reductase genes identified with oligonucleotide probes in plasmids from isolates of commensal faecal flora. J Antimicrob Chemother 1995 0.94
66 Fatal infection caused by a multiply resistant type 3 pneumococcus. J Clin Microbiol 1988 0.94
67 Emergence of a pneumococcal clone with cephalosporin resistance and penicillin susceptibility. Antimicrob Agents Chemother 2001 0.94
68 Impact of cotrimoxazole on non-susceptibility to antibiotics in Streptococcus pneumoniae carriage isolates among HIV-infected mineworkers in South Africa. J Infect 2008 0.93
69 New trimethoprim-resistant dihydrofolate reductase cassette, dfrXV, inserted in a class 1 integron. Antimicrob Agents Chemother 1998 0.90
70 Pneumococcal and Haemophilus influenzae meningitis in a children's hospital in Ethiopia: serotypes and susceptibility patterns. Trop Med Int Health 1999 0.90
71 Bacteremic pneumonia caused by penicillin-resistant pneumococci. N Engl J Med 1988 0.90
72 Meningitis and pneumonia due to novel multiply resistant pneumococci. Br Med J (Clin Res Ed) 1986 0.89
73 The molecular mechanisms of tetracycline resistance in the pneumococcus. Microb Drug Resist 1998 0.89
74 Use of Dorset egg medium for maintenance and transport of Neisseria meningitidis and Haemophilus influenzae type b. J Clin Microbiol 1999 0.88
75 Body mass and sex as determining factors in the development of fever in rats. J Physiol 1980 0.88
76 Analysis of penicillin-binding protein lb and 2a genes from Streptococcus pneumoniae. Microb Drug Resist 2000 0.88
77 Application of pbp1A PCR in identification of penicillin-resistant Streptococcus pneumoniae. J Clin Microbiol 1999 0.87
78 Recurrent penicillin-resistant pneumococcal meningitis after chloramphenicol therapy. Pediatr Infect Dis J 1991 0.87
79 Prevalence of nasopharyngeal antibiotic-resistant pneumococcal carriage in children attending private paediatric practices in Johannesburg. S Afr Med J 2000 0.86
80 Increased resistance to amikacin in a neonatal unit following intensive amikacin usage. Antimicrob Agents Chemother 1992 0.85
81 Estimating the prevalence of coinfection with influenza virus and the atypical bacteria Bordetella pertussis, Chlamydophila pneumoniae, and Mycoplasma pneumoniae. Eur J Clin Microbiol Infect Dis 2014 0.85
82 Cerebrospinal fluid bactericidal activity against cephalosporin-resistant Streptococcus pneumoniae in children with meningitis treated with high-dosage cefotaxime. Antimicrob Agents Chemother 1997 0.84
83 Actinobacillus (Pasteurella) ureae meningitis in a HIV-positive patient. Diagn Microbiol Infect Dis 1994 0.84
84 Differing manifestations of respiratory syncytial virus-associated severe lower respiratory tract infections in human immunodeficiency virus type 1-infected and uninfected children. Pediatr Infect Dis J 2001 0.83
85 Control of methicillin-resistant Staphylococcus aureus bacteraemia in high-risk areas. Eur J Clin Microbiol Infect Dis 1994 0.83
86 Prevalence and genetic location of non-transferable trimethoprim resistant dihydrofolate reductase genes in South African commensal faecal isolates. Epidemiol Infect 1995 0.83
87 The paradox in pneumococcal serotypes: highly invasive does not mean highly lethal. Eur Respir J 2010 0.82
88 Community-acquired pneumonia in an adult due to a multiply-resistant pneumococcus. J Infect 1987 0.82
89 Severe lower respiratory tract infections associated with human parainfluenza viruses 1-3 in children infected and noninfected with HIV type 1. Eur J Clin Microbiol Infect Dis 2002 0.82
90 Ciprofloxacin treatment failure in a patient with resistant Streptococcus pneumoniae infection following prior ciprofloxacin therapy. Eur J Clin Microbiol Infect Dis 2005 0.82
91 Antibiotic resistance in pneumococcal meningitis. Lancet 1992 0.81
92 Impact of antimicrobial resistance and antibiotic choice on the outcome of pneumococcal meningitis. S Afr Med J 1997 0.80
93 Clarithromycin alone and in combination with ceftriaxone inhibits the production of pneumolysin by both macrolide-susceptible and macrolide-resistant strains of Streptococcus pneumoniae. J Antimicrob Chemother 2007 0.80
94 Incidence of high-level gentamicin resistance in enterococci at Johannesburg Hospital. S Afr Med J 1996 0.80
95 Future trends in antimicrobial chemotherapy: expert opinion on the 43rd ICAAC. J Chemother 2004 0.80
96 Mutations within the rplD Gene of Linezolid-Nonsusceptible Streptococcus pneumoniae Strains Isolated in the United States. Antimicrob Agents Chemother 2014 0.80
97 In-vitro activity of cefepime against bacterial pathogens from hospitalized patients. J Antimicrob Chemother 1993 0.79
98 Epidemic Shigella dysentery in South Africa. S Afr Med J 1997 0.79
99 Activity of teicoplanin and vancomycin against penicillin-resistant pneumococci. Eur J Clin Microbiol Infect Dis 1994 0.79
100 Pneumococci resistant to extended-spectrum cephalosporins in South Africa. Lancet 1993 0.78
101 AIDS--the Baragwanath experience. Part I. Epidemiology of HIV infection at Baragwanath Hospital, 1988-1990. S Afr Med J 1992 0.77
102 Evolution of extended spectrum cephalosporin resistance in the pneumococcus. J Antimicrob Chemother 1997 0.77
103 Septic arthritis due to Cryptococcus neoformans. J Infect 1988 0.77
104 Penetration of cefpodoxime into middle ear fluid in pediatric patients with acute otitis media. Pediatr Infect Dis J 1997 0.77
105 Antibiotic resistance of nasopharyngeal isolates of Streptococcus pneumoniae from children in Lesotho. Bull World Health Organ 1998 0.76
106 Current MIC breakpoints may understate the potential efficacies of carbapenems for treatment of patients with infections caused by strains of Streptococcus pneumoniae that are resistant or of intermediate susceptibility to penicillin. J Antimicrob Chemother 1998 0.76
107 Substance P increases hypothalamic blood flow via an indirect adrenergic-cholinergic interaction. Br J Pharmacol 1980 0.75
108 Contrasting roles of 5-hydroxytryptamine and noradrenaline in fever in rats. J Physiol 1980 0.75
109 Disk susceptibility testing of penicillin-resistant pneumococci. J Clin Microbiol 1988 0.75
110 Levofloxacin-resistant pneumococcus. Clin Infect Dis 2000 0.75
111 Penicillin-resistant pneumococcal meningitis. Lancet 1997 0.75
112 Effects of haemorrhage on colloid osmotic pressure in the pigeon. Comp Biochem Physiol A Comp Physiol 1982 0.75
113 Comparative in vitro activity of piperacillin/tazobactam against gram-negative bacilli. S Afr Med J 1996 0.75
114 Serotypes and antibacterial susceptibility of pneumococci isolated from children with infections in Ankara in relation to proposed pneumococcal vaccine coverage. Acta Paediatr Jpn 1998 0.75
115 Detection of Penicillin Resistance in Streptococcus pneumoniae by a Seminested PCR Strategy. Methods Mol Med 2001 0.75
116 Centres of excellence for academic medicine in South Africa. S Afr Med J 1994 0.75
117 Rationale for a hospital-based pneumococcal vaccine trial for HIV-seropositive South Africans. Int J Infect Dis 2000 0.75
118 Lifelong antihypertensive therapy. S Afr Med J 1980 0.75
119 Infection of the human orbit by Aspergillus stromatoides. Case report. Mycopathologia 1987 0.75
120 Antimicrobial resistance--fluoroquinolones and the tiger's tail. J Chemother 2006 0.75
121 Serotype and antimicrobial susceptibility patterns of Haemophilus influenzae isolates from inpatients and outpatients in Johannesburg. S Afr Med J 1989 0.75
122 Cholinergic regulation of intracerebral noradrenergic pathway-induced hypothalamic vasodilatation. Stroke 1980 0.75
123 Pneumococcal diseases. Methods Mol Med 1998 0.75
124 Bacterial enteritis of infancy and childhood in Soweto. S Afr Med J 1986 0.75
125 Antimicrobial susceptibility of pneumococcal isolates causing bacteraemic pneumococcal pneumonia: analysis using current breakpoints and fluoroquinolone pharmacodynamics. Int J Antimicrob Agents 2010 0.75
126 Epidemiology of HIV infection in pregnant women. Nurs RSA 1992 0.75
127 An evaluation of two indirect fluorescent antibody tests for the diagnosis of Legionnaire's disease in South Africa. S Afr Med J 1990 0.75
128 Corynebacterium group D2 urinary tract infection. S Afr Med J 1993 0.75
129 Pneumococcal conjugate vaccine--prospects for intervention in children. Semin Respir Infect 1999 0.75
130 Advances in the management of penicillin-resistant pneumococcal meningitis. S Afr Med J 1992 0.75
131 Implications of bacterial resistance for the use of beta-lactam agents in clinical practice. S Afr Med J 1993 0.75