Published in Toxicol Sci on December 08, 2004
Transient receptor potential ankyrin 1 mediates toluene diisocyanate-evoked respiratory irritation. Am J Respir Cell Mol Biol (2008) 1.14
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Choice of mouse strain influences the outcome in a mouse model of chemical-induced asthma. PLoS One (2010) 0.95
Environmental isocyanate-induced asthma: morphologic and pathogenetic aspects of an increasing occupational disease. Int J Environ Res Public Health (2011) 0.93
Biomonitoring Hexamethylene diisocyanate (HDI) exposure based on serum levels of HDI-specific IgG. Ann Occup Hyg (2012) 0.88
Nanotoxicity overview: nano-threat to susceptible populations. Int J Mol Sci (2014) 0.86
The cardiac protein αT-catenin contributes to chemical-induced asthma. Am J Physiol Lung Cell Mol Physiol (2014) 0.84
Monoclonal antibodies against toluene diisocyanate haptenated proteins from vapor-exposed mice. Hybridoma (Larchmt) (2010) 0.83
B-lymphocytes as key players in chemical-induced asthma. PLoS One (2013) 0.79
Characterization and comparative analysis of 2,4-toluene diisocyanate and 1,6-hexamethylene diisocyanate haptenated human serum albumin and hemoglobin. J Immunol Methods (2016) 0.75
Inhalation of ortho-phthalaldehyde vapor causes respiratory sensitization in mice. J Allergy (Cairo) (2011) 0.75
Fasting mitigates immediate hypersensitivity: a pivotal role of endogenous D-beta-hydroxybutyrate. Nutr Metab (Lond) (2014) 0.75
Toluene diisocyanate (TDI) airway effects and dose-responses in different animal models. EXCLI J (2012) 0.75
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Isocyanates and work-related asthma: Findings from California, Massachusetts, Michigan, and New Jersey, 1993-2008. Am J Ind Med (2015) 0.75
Unusual inflammatory and fibrogenic pulmonary responses to single-walled carbon nanotubes in mice. Am J Physiol Lung Cell Mol Physiol (2005) 7.28
Reductions in serum lipids with a 4-year decline in serum perfluorooctanoic acid and perfluorooctanesulfonic acid. Epidemiology (2013) 2.13
Mice deficient in TNF receptors are protected against dopaminergic neurotoxicity: implications for Parkinson's disease. FASEB J (2002) 1.79
Deficiency of TNF receptors suppresses microglial activation and alters the susceptibility of brain regions to MPTP-induced neurotoxicity: role of TNF-alpha. FASEB J (2006) 1.61
Cardiovascular effects of pulmonary exposure to single-wall carbon nanotubes. Environ Health Perspect (2006) 1.57
Immunotoxicity of perfluorooctanoic acid and perfluorooctane sulfonate and the role of peroxisome proliferator-activated receptor alpha. Crit Rev Toxicol (2009) 1.55
Unrestrained acoustic plethysmograph for measuring specific airway resistance in mice. J Appl Physiol (1985) (2008) 1.50
Physiological role of tumor necrosis factor alpha in traumatic muscle injury. FASEB J (2002) 1.42
Arsenic and atherosclerosis. Toxicol Appl Pharmacol (2004) 1.33
Arsenic exposure accelerates atherogenesis in apolipoprotein E(-/-) mice. Environ Health Perspect (2003) 1.22
Role of CC chemokines in skeletal muscle functional restoration after injury. Am J Physiol Cell Physiol (2004) 1.14
c-Src-dependent activation of the epidermal growth factor receptor and mitogen-activated protein kinase pathway by arsenic. Role in carcinogenesis. J Biol Chem (2001) 1.08
Genotyping of single nucleotide polymorphisms in cytokine genes using real-time PCR allelic discrimination technology. Cytokine (2004) 1.07
Inhalation of toluene diisocyanate vapor induces allergic rhinitis in mice. J Immunol (2007) 1.06
Irritancy and allergic responses induced by topical application of ortho-phthalaldehyde. Toxicol Sci (2010) 1.03
Selenium attenuates lipopolysaccharide-induced oxidative stress responses through modulation of p38 MAPK and NF-kappaB signaling pathways. Exp Biol Med (Maywood) (2004) 0.99
Leucine-rich repeat kinase 2 (LRRK2)-deficient rats exhibit renal tubule injury and perturbations in metabolic and immunological homeostasis. PLoS One (2013) 0.98
Meeting report: moving upstream-evaluating adverse upstream end points for improved risk assessment and decision-making. Environ Health Perspect (2008) 0.98
Cytokine polymorphisms in silicosis and other pneumoconioses. Mol Cell Biochem (2002) 0.98
Inflammatory mediators and skeletal muscle injury: a DNA microarray analysis. J Interferon Cytokine Res (2003) 0.97
Influence of cytokine gene variations on immunization to childhood vaccines. Vaccine (2009) 0.97
Prevention of IL-1 signaling attenuates airway hyperresponsiveness and inflammation in a murine model of toluene diisocyanate-induced asthma. J Allergy Clin Immunol (2005) 0.95
The comparative immunotoxicity of five selected compounds following developmental or adult exposure. J Toxicol Environ Health B Crit Rev (2006) 0.95
Production, characterization and utility of a panel of monoclonal antibodies for the detection of toluene diisocyanate haptenated proteins. J Immunol Methods (2011) 0.93
Immune mediators in a murine model for occupational asthma: studies with toluene diisocyanate. Toxicol Sci (2004) 0.93
CTNNA3 (α-catenin) gene variants are associated with diisocyanate asthma: a replication study in a Caucasian worker population. Toxicol Sci (2012) 0.93
Biomarkers to assess potential developmental immunotoxicity in children. Toxicol Appl Pharmacol (2005) 0.90
Influenza vaccine response in adults exposed to perfluorooctanoate and perfluorooctanesulfonate. Toxicol Sci (2013) 0.90
Cytokine polymorphisms play a role in susceptibility to ultraviolet B-induced modulation of immune responses after hepatitis B vaccination. J Immunol (2003) 0.90
Role of tumor necrosis factor in toluene diisocyanate asthma. Am J Respir Cell Mol Biol (2002) 0.89
Signaling pathways of bisphenol A-induced apoptosis in hippocampal neuronal cells: role of calcium-induced reactive oxygen species, mitogen-activated protein kinases, and nuclear factor-kappaB. J Neurosci Res (2008) 0.89
IL-1beta gene polymorphisms influence hepatitis B vaccination. Vaccine (2002) 0.89
Maternal treatment with a high dose of CpG ODN during gestation alters fetal craniofacial and distal limb development in C57BL/6 mice. Vaccine (2005) 0.89
Effects of titanium dioxide nanoparticle exposure on neuroimmune responses in rat airways. J Toxicol Environ Health A (2010) 0.88
Mercury inhibits nitric oxide production but activates proinflammatory cytokine expression in murine macrophage: differential modulation of NF-kappaB and p38 MAPK signaling pathways. Nitric Oxide (2002) 0.88
Genetic variants within the MHC region are associated with immune responsiveness to childhood vaccinations. Vaccine (2013) 0.86
Extracellular signal-regulated kinase-signaling-dependent G2/M arrest and cell death in murine macrophages by cadmium. Environ Toxicol Chem (2005) 0.85
Genetic susceptibility in pneumoconiosis. Toxicol Lett (2006) 0.85
Association of osteoarthritis with serum levels of the environmental contaminants perfluorooctanoate and perfluorooctane sulfonate in a large Appalachian population. Am J Epidemiol (2011) 0.84
Symposium summary: children's health risk--what's so special about the developing immune system? Toxicol Appl Pharmacol (2004) 0.83
Monoclonal antibodies against toluene diisocyanate haptenated proteins from vapor-exposed mice. Hybridoma (Larchmt) (2010) 0.83
Hexamethylene diisocyanate asthma is associated with genetic polymorphisms of CD14, IL-13, and IL-4 receptor α. J Allergy Clin Immunol (2011) 0.82
Suppression of immune function and susceptibility to infections in humans: association of immune function with clinical disease. J Immunotoxicol (2004) 0.82
Association of interleukin-1 gene polymorphisms with dementia in a community-based sample: the Honolulu-Asia Aging Study. Neurobiol Aging (2005) 0.82
Genetic variants in antioxidant genes are associated with diisocyanate-induced asthma. Toxicol Sci (2012) 0.82
Winter season, frequent hand washing, and irritant patch test reactions to detergents are associated with hand dermatitis in health care workers. Dermatitis (2013) 0.82
Arsenic carcinogenicity: relevance of c-Src activation. Mol Cell Biochem (2002) 0.81
Myriocin, a serine palmitoyltransferase inhibitor, alters regional brain neurotransmitter levels without concurrent inhibition of the brain sphingolipid biosynthesis in mice. Toxicol Lett (2004) 0.80
A proposed testing framework for developmental immunotoxicology (DIT). Toxicol Sci (2004) 0.80
Genetic variants in the major histocompatibility complex class I and class II genes are associated with diisocyanate-induced Asthma. J Occup Environ Med (2014) 0.79
Inhibition of serine palmitoyltransferase by myriocin, a natural mycotoxin, causes induction of c-myc in mouse liver. Mycopathologia (2004) 0.79
Animal models for diisocyanate asthma: answers for lingering questions. Curr Opin Allergy Clin Immunol (2004) 0.79
Insights into the quantitative relationship between sensitization and challenge for allergic contact dermatitis reactions. Toxicol Appl Pharmacol (2002) 0.79
Oral exposure to inorganic mercury alters T lymphocyte phenotypes and cytokine expression in BALB/c mice. Arch Toxicol (2003) 0.78
Genetic variability in susceptibility to occupational respiratory sensitization. J Allergy (Cairo) (2011) 0.78
A statistical model for assessing genetic susceptibility as a risk factor in multifactorial diseases: lessons from occupational asthma. Environ Health Perspect (2006) 0.78
Immunotoxicology testing: past and future. Methods Mol Biol (2010) 0.77
Benzene and Its Principal Metabolites Modulate Proinflammatory Cytokines and Growth Factors in Human Epidermal Keratinocyte Cultures. In Vitro Toxicol (1997) 0.77
Immunotoxicogenomics: the potential of genomics technology in the immunotoxicity risk assessment process. Toxicol Sci (2006) 0.77
Deletion of IFN-gamma reduces fumonisin-induced hepatotoxicity in mice via alterations in inflammatory cytokines and apoptotic factors. J Interferon Cytokine Res (2003) 0.77
Association of cytokine gene polymorphisms with rate of decline in lung function. J Occup Environ Med (2008) 0.77
Quinacrine-induced occlusive fibrosis in the human fallopian tube is due to a unique inflammatory response and modification of repair mechanisms. J Reprod Immunol (2013) 0.76
Increased expression of CD95-ligand and other apoptotic signaling factors by fumonisin B1, a hepatotoxic mycotoxin, in livers of mice lacking tumor necrosis factor alpha. Cytokine (2003) 0.76
Variation in the WBC differential count and other factors associated with reporting of herpes labialis: a population-based study of adults. FEMS Immunol Med Microbiol (2007) 0.76
Physiological responses to a natural antioxidant flavonoid mixture, silymarin, in BALB/c mice: I induction of transforming growth factor beta1 and c-myc in liver with marginal effects on other genes. Planta Med (2002) 0.76
Cytokine polymorphisms in chronic inflammatory diseases with reference to occupational diseases. Curr Mol Med (2003) 0.76
Sodium selenite-induced apoptosis in murine B-lymphoma cells is associated with inhibition of protein kinase C-delta, nuclear factor kappaB, and inhibitor of apoptosis protein. Toxicol Sci (2004) 0.76
An alternative interpretation of, "A lifetime cancer bioassay of quinacrine administered into the uterine horns of female rats". Regul Toxicol Pharmacol (2010) 0.75
Genetic Basis of Irritant Susceptibility in Health Care Workers. J Occup Environ Med (2016) 0.75
N-Acetyltransferase 2 Genotypes Are Associated With Diisocyanate-Induced Asthma. J Occup Environ Med (2015) 0.75
Challenge exposure to isocyanates induces changes in nasal patency in patients reporting work-related respiratory symptoms. J Occup Environ Med (2013) 0.75
Mice lacking both TNFalpha receptors show increased constitutive expression of IFNgamma: a possible reason for lack of protection from fumonisin B1 hepatotoxicity. Cytokine (2006) 0.75
Immunotoxicology: fifty years of global scientific progress. J Immunotoxicol (2012) 0.75