Published in J Biol Chem on November 26, 2001
Arsenic exposure and toxicology: a historical perspective. Toxicol Sci (2011) 2.63
Genetic and epigenetic mechanisms in metal carcinogenesis and cocarcinogenesis: nickel, arsenic, and chromium. Chem Res Toxicol (2007) 2.59
Influence of arsenate and arsenite on signal transduction pathways: an update. Arch Toxicol (2010) 1.76
Arsenic activates EGFR pathway signaling in the lung. Toxicol Sci (2009) 1.53
Metabolism and toxicity of arsenic in human urothelial cells expressing rat arsenic (+3 oxidation state)-methyltransferase. Toxicol Appl Pharmacol (2005) 1.52
Src kinase becomes preferentially associated with the VEGFR, KDR/Flk-1, following VEGF stimulation of vascular endothelial cells. BMC Biochem (2002) 1.23
Transmodulation between phospholipase D and c-Src enhances cell proliferation. Mol Cell Biol (2003) 1.15
Arsenite and insulin exhibit opposing effects on epidermal growth factor receptor and keratinocyte proliferative potential. Toxicol Appl Pharmacol (2007) 1.03
Akt activation is responsible for enhanced migratory and invasive behavior of arsenic-transformed human bronchial epithelial cells. Environ Health Perspect (2011) 1.00
The prostaglandin E2 receptor, EP2, stimulates keratinocyte proliferation in mouse skin by G protein-dependent and {beta}-arrestin1-dependent signaling pathways. J Biol Chem (2010) 0.96
Pemphigus vulgaris IgG cause loss of desmoglein-mediated adhesion and keratinocyte dissociation independent of epidermal growth factor receptor. Am J Pathol (2009) 0.93
SRC tyrosine kinase inhibitor, m475271, suppresses subcutaneous growth and production of lung metastasis via inhibition of proliferation, invasion, and vascularization of human lung adenocarcinoma cells. Clin Exp Metastasis (2005) 0.84
The role of reactive oxygen species in arsenite and monomethylarsonous acid-induced signal transduction in human bladder cells: acute studies. Toxicology (2008) 0.84
Arsenic activates endothelin-1 Gi protein-coupled receptor signaling to inhibit stem cell differentiation in adipogenesis. Toxicol Sci (2012) 0.83
Reactive oxygen species regulate properties of transformation in UROtsa cells exposed to monomethylarsonous acid by modulating MAPK signaling. Toxicology (2008) 0.83
Manganese superoxide dismutase-mediated inside-out signaling in HaCaT human keratinocytes and SKH-1 mouse skin. Antioxid Redox Signal (2014) 0.81
Requirement of ERα and basal activities of EGFR and Src kinase in Cd-induced activation of MAPK/ERK pathway in human breast cancer MCF-7 cells. Toxicol Appl Pharmacol (2015) 0.81
Involvement of epigenetics and EMT-related miRNA in arsenic-induced neoplastic transformation and their potential clinical use. Cancer Prev Res (Phila) (2015) 0.79
Arsenic alters vascular smooth muscle cell focal adhesion complexes leading to activation of FAK-src mediated pathways. Toxicol Appl Pharmacol (2008) 0.77
Growth factor dependent regulation of centrosome function and genomic instability by HuR. Biomolecules (2015) 0.76
Increased growth-inhibitory and cytotoxic activity of arsenic trioxide in head and neck carcinoma cells with functional p53 deficiency and resistance to EGFR blockade. PLoS One (2014) 0.76
Reductions in serum lipids with a 4-year decline in serum perfluorooctanoic acid and perfluorooctanesulfonic acid. Epidemiology (2013) 2.13
Macrophages and skeletal muscle regeneration: a clodronate-containing liposome depletion study. Am J Physiol Regul Integr Comp Physiol (2006) 1.94
Mice deficient in TNF receptors are protected against dopaminergic neurotoxicity: implications for Parkinson's disease. FASEB J (2002) 1.79
Deficiency of TNF receptors suppresses microglial activation and alters the susceptibility of brain regions to MPTP-induced neurotoxicity: role of TNF-alpha. FASEB J (2006) 1.61
Chemokine receptor CCR2 involvement in skeletal muscle regeneration. FASEB J (2004) 1.58
Cardiovascular effects of pulmonary exposure to single-wall carbon nanotubes. Environ Health Perspect (2006) 1.57
Immunotoxicity of perfluorooctanoic acid and perfluorooctane sulfonate and the role of peroxisome proliferator-activated receptor alpha. Crit Rev Toxicol (2009) 1.55
Physiological role of tumor necrosis factor alpha in traumatic muscle injury. FASEB J (2002) 1.42
Carbon nanotube dosimetry: from workplace exposure assessment to inhalation toxicology. Part Fibre Toxicol (2013) 1.33
Arsenic and atherosclerosis. Toxicol Appl Pharmacol (2004) 1.33
Identification and characterization of asparagine deamidation in the light chain CDR1 of a humanized IgG1 antibody. Anal Biochem (2009) 1.31
Characterization of HIV type 1 heterosexual transmission in Yunnan, China. AIDS Res Hum Retroviruses (2003) 1.24
Cross-talk between lung and systemic circulation during carbon nanotube respiratory exposure. Potential biomarkers. Nano Lett (2009) 1.22
Arsenic exposure accelerates atherogenesis in apolipoprotein E(-/-) mice. Environ Health Perspect (2003) 1.22
Role of CC chemokines in skeletal muscle functional restoration after injury. Am J Physiol Cell Physiol (2004) 1.14
Genotyping of single nucleotide polymorphisms in cytokine genes using real-time PCR allelic discrimination technology. Cytokine (2004) 1.07
Inhalation of toluene diisocyanate vapor induces allergic rhinitis in mice. J Immunol (2007) 1.06
Exposure and immunological determinants in a murine model for toluene diisocyanate (TDI) asthma. Toxicol Sci (2004) 1.04
Mechanisms of skeletal muscle injury and repair revealed by gene expression studies in mouse models. J Physiol (2007) 1.03
Potential in vitro effects of carbon nanotubes on human aortic endothelial cells. Toxicol Appl Pharmacol (2009) 0.99
Meeting report: moving upstream-evaluating adverse upstream end points for improved risk assessment and decision-making. Environ Health Perspect (2008) 0.98
Identification of systemic markers from a pulmonary carbon nanotube exposure. J Occup Environ Med (2011) 0.98
Cytokine polymorphisms in silicosis and other pneumoconioses. Mol Cell Biochem (2002) 0.98
Inflammatory mediators and skeletal muscle injury: a DNA microarray analysis. J Interferon Cytokine Res (2003) 0.97
Influence of cytokine gene variations on immunization to childhood vaccines. Vaccine (2009) 0.97
Prevention of IL-1 signaling attenuates airway hyperresponsiveness and inflammation in a murine model of toluene diisocyanate-induced asthma. J Allergy Clin Immunol (2005) 0.95
The comparative immunotoxicity of five selected compounds following developmental or adult exposure. J Toxicol Environ Health B Crit Rev (2006) 0.95
Inhalation exposure of gas-metal arc stainless steel welding fume increased atherosclerotic lesions in apolipoprotein E knockout mice. Toxicol Lett (2011) 0.94
Immune mediators in a murine model for occupational asthma: studies with toluene diisocyanate. Toxicol Sci (2004) 0.93
CTNNA3 (α-catenin) gene variants are associated with diisocyanate asthma: a replication study in a Caucasian worker population. Toxicol Sci (2012) 0.93
Isolation and characterization of IgG1 with asymmetrical Fc glycosylation. Glycobiology (2011) 0.93
Influenza vaccine response in adults exposed to perfluorooctanoate and perfluorooctanesulfonate. Toxicol Sci (2013) 0.90
Cytokine polymorphisms play a role in susceptibility to ultraviolet B-induced modulation of immune responses after hepatitis B vaccination. J Immunol (2003) 0.90
Arginase activities and global arginine bioavailability in wild-type and ApoE-deficient mice: responses to high fat and high cholesterol diets. PLoS One (2010) 0.90
Role of tumor necrosis factor in toluene diisocyanate asthma. Am J Respir Cell Mol Biol (2002) 0.89
Maternal treatment with a high dose of CpG ODN during gestation alters fetal craniofacial and distal limb development in C57BL/6 mice. Vaccine (2005) 0.89
IL-1beta gene polymorphisms influence hepatitis B vaccination. Vaccine (2002) 0.89
Relationship between pulmonary and systemic markers of exposure to multiple types of welding particulate matter. Toxicology (2011) 0.87
Genetic variants within the MHC region are associated with immune responsiveness to childhood vaccinations. Vaccine (2013) 0.86
Genetic susceptibility in pneumoconiosis. Toxicol Lett (2006) 0.85
Association of osteoarthritis with serum levels of the environmental contaminants perfluorooctanoate and perfluorooctane sulfonate in a large Appalachian population. Am J Epidemiol (2011) 0.84
Symposium summary: children's health risk--what's so special about the developing immune system? Toxicol Appl Pharmacol (2004) 0.83
Calretinin regulates Ca2+-dependent inactivation and facilitation of Ca(v)2.1 Ca2+ channels through a direct interaction with the α12.1 subunit. J Biol Chem (2012) 0.83
Winter season, frequent hand washing, and irritant patch test reactions to detergents are associated with hand dermatitis in health care workers. Dermatitis (2013) 0.82
Genetic variants in antioxidant genes are associated with diisocyanate-induced asthma. Toxicol Sci (2012) 0.82
Association of interleukin-1 gene polymorphisms with dementia in a community-based sample: the Honolulu-Asia Aging Study. Neurobiol Aging (2005) 0.82
Suppression of immune function and susceptibility to infections in humans: association of immune function with clinical disease. J Immunotoxicol (2004) 0.82
Generation of vectorial optical fields with slot-antenna-based metasurface. Opt Lett (2015) 0.82
Hexamethylene diisocyanate asthma is associated with genetic polymorphisms of CD14, IL-13, and IL-4 receptor α. J Allergy Clin Immunol (2011) 0.82
Arsenic carcinogenicity: relevance of c-Src activation. Mol Cell Biochem (2002) 0.81
A proposed testing framework for developmental immunotoxicology (DIT). Toxicol Sci (2004) 0.80
Insights into the quantitative relationship between sensitization and challenge for allergic contact dermatitis reactions. Toxicol Appl Pharmacol (2002) 0.79
Type I interferon and pattern recognition receptor signaling following particulate matter inhalation. Part Fibre Toxicol (2012) 0.79
Animal models for diisocyanate asthma: answers for lingering questions. Curr Opin Allergy Clin Immunol (2004) 0.79
Genetic variants in the major histocompatibility complex class I and class II genes are associated with diisocyanate-induced Asthma. J Occup Environ Med (2014) 0.79
A statistical model for assessing genetic susceptibility as a risk factor in multifactorial diseases: lessons from occupational asthma. Environ Health Perspect (2006) 0.78
Toll-like and adenosine receptor expression in injured skeletal muscle. Muscle Nerve (2011) 0.78
Oxidative stress and reduced responsiveness of challenged circulating leukocytes following pulmonary instillation of metal-rich particulate matter in rats. Part Fibre Toxicol (2014) 0.78
Benzene and Its Principal Metabolites Modulate Proinflammatory Cytokines and Growth Factors in Human Epidermal Keratinocyte Cultures. In Vitro Toxicol (1997) 0.77
Immunotoxicogenomics: the potential of genomics technology in the immunotoxicity risk assessment process. Toxicol Sci (2006) 0.77
Immunotoxicology testing: past and future. Methods Mol Biol (2010) 0.77
Separation of rotavirus double-layered particles and triple-layered particles by capillary zone electrophoresis. J Virol Methods (2010) 0.77
Association of cytokine gene polymorphisms with rate of decline in lung function. J Occup Environ Med (2008) 0.77
Reduction in dynamin-2 is implicated in ischaemic cardiac arrhythmias. J Cell Mol Med (2014) 0.76
CXCR1/CXCR2 antagonism is effective in pulmonary defense against Klebsiella pneumoniae infection. Biomed Res Int (2013) 0.76
Variation in the WBC differential count and other factors associated with reporting of herpes labialis: a population-based study of adults. FEMS Immunol Med Microbiol (2007) 0.76
Cytokine polymorphisms in chronic inflammatory diseases with reference to occupational diseases. Curr Mol Med (2003) 0.76
Quinacrine-induced occlusive fibrosis in the human fallopian tube is due to a unique inflammatory response and modification of repair mechanisms. J Reprod Immunol (2013) 0.76
An alternative interpretation of, "A lifetime cancer bioassay of quinacrine administered into the uterine horns of female rats". Regul Toxicol Pharmacol (2010) 0.75
Genetic Basis of Irritant Susceptibility in Health Care Workers. J Occup Environ Med (2016) 0.75
N-Acetyltransferase 2 Genotypes Are Associated With Diisocyanate-Induced Asthma. J Occup Environ Med (2015) 0.75
Immunotoxicology: fifty years of global scientific progress. J Immunotoxicol (2012) 0.75
Citrate-mediated disaggregation of rotavirus particles in RotaTeq vaccine. Antiviral Res (2005) 0.75