Microbial hyaluronic acid production.

Hybrid multicomponent hydrogels for tissue engineering. Macromol Biosci (2009) 1.37

Hydrogels for the repair of articular cartilage defects. Tissue Eng Part B Rev (2011) 1.35

Hyaluronic Acid-Based Hydrogels: from a Natural Polysaccharide to Complex Networks. Soft Matter (2012) 1.12

Microbial production of hyaluronic acid: current state, challenges, and perspectives. Microb Cell Fact (2011) 1.09

Evolution of the hyaluronic acid synthesis (has) operon in Streptococcus zooepidemicus and other pathogenic streptococci. J Mol Evol (2008) 1.02

Escherichia coli K5 heparosan fermentation and improvement by genetic engineering. Bioeng Bugs (2011) 0.97

Chondroitin sulfate, hyaluronic acid and chitin/chitosan production using marine waste sources: characteristics, applications and eco-friendly processes: a review. Mar Drugs (2013) 0.96

Hyaluronan molecular weight is controlled by UDP-N-acetylglucosamine concentration in Streptococcus zooepidemicus. J Biol Chem (2009) 0.95

Polysaccharide-modified synthetic polymeric biomaterials. Biopolymers (2010) 0.94

Bacterial exopolysaccharides: biosynthesis pathways and engineering strategies. Front Microbiol (2015) 0.94

Hyaluronic acid production by Streptococcus zooepidemicus in marine by-products media from mussel processing wastewaters and tuna peptone viscera. Microb Cell Fact (2010) 0.91

High cell density cultivation of Escherichia coli K4 in a microfiltration bioreactor: a step towards improvement of chondroitin precursor production. Microb Cell Fact (2011) 0.88

Metabolic engineering of microbes for oligosaccharide and polysaccharide synthesis. Microb Cell Fact (2006) 0.87

Optimization of medium components for high-molecular-weight hyaluronic acid production by Streptococcus sp. ID9102 via a statistical approach. J Ind Microbiol Biotechnol (2009) 0.87

Compositional analysis and structural elucidation of glycosaminoglycans in chicken eggs. Glycoconj J (2014) 0.80

Purification and biocompatibility of fermented hyaluronic acid for its applications to biomaterials. Biomater Res (2014) 0.80

Present and future medical applications of microbial exopolysaccharides. Front Microbiol (2015) 0.79

Biocompatible blood pool MRI contrast agents based on hyaluronan. Contrast Media Mol Imaging (2010) 0.78

Application of polysaccharides for surface modification of nanomedicines. Ther Deliv (2012) 0.77

Genetic basis for hyper production of hyaluronic acid in natural and engineered microorganisms. Microb Cell Fact (2016) 0.77

Heterologous Production of Hyaluronic Acid in an ε-Poly-L-Lysine Producer, Streptomyces albulus. Appl Environ Microbiol (2015) 0.76

Construction of efficient Streptococcus zooepidemicus strains for hyaluoronic acid production based on identification of key genes involved in sucrose metabolism. AMB Express (2016) 0.75

Biotechnological production of hyaluronic acid: a mini review. 3 Biotech (2016) 0.75

Cashew apple juice as microbial cultivation medium for non-immunogenic hyaluronic acid production. Braz J Microbiol (2014) 0.75

Green synthesis, characterization, and anticancer activity of hyaluronan/zinc oxide nanocomposite. Onco Targets Ther (2016) 0.75

Optimization of flask culture medium and conditions for hyaluronic acid production by a Streptococcus equisimilis mutant nc2168. Braz J Microbiol (2012) 0.75

Endotoxin free hyaluronan and hyaluronan fragments do not stimulate TNF-α, interleukin-12 or upregulate co-stimulatory molecules in dendritic cells or macrophages. Sci Rep (2016) 0.75

Bio-conjugated polycaprolactone membranes: a novel wound dressing. Arch Plast Surg (2014) 0.75

Drug Carriers: Not an Innocent Delivery Man. AAPS J (2015) 0.75

Production of Hyaluronic Acid by Streptococcus zooepidemicus on Protein Substrates Obtained from Scyliorhinus canicula Discards. Mar Drugs (2015) 0.75

Genetic and functional characterization of the hyaluronate lyase HylB and the beta-N-acetylglucosaminidase HylZ in Streptococcus zooepidemicus. Curr Microbiol (2014) 0.75

Method for generation of homogeneous multicellular tumor spheroids applicable to a wide variety of cell types. Biotechnol Bioeng (2003) 3.04

Metabolic functions of duplicate genes in Saccharomyces cerevisiae. Genome Res (2005) 2.68

Fermentative butanol production by Clostridia. Biotechnol Bioeng (2008) 2.49

Towards quantitative metabolomics of mammalian cells: development of a metabolite extraction protocol. Anal Biochem (2010) 2.17

Molecular composition of IMP1 ribonucleoprotein granules. Mol Cell Proteomics (2007) 1.80

The genome sequence of E. coli W (ATCC 9637): comparative genome analysis and an improved genome-scale reconstruction of E. coli. BMC Genomics (2011) 1.63

OpenFLUX: efficient modelling software for 13C-based metabolic flux analysis. Microb Cell Fact (2009) 1.61

Modeling hybridoma cell metabolism using a generic genome-scale metabolic model of Mus musculus. Biotechnol Prog (2005) 1.60

DNase I-hypersensitive exons colocalize with promoters and distal regulatory elements. Nat Genet (2013) 1.40

Growth independent rhamnolipid production from glucose using the non-pathogenic Pseudomonas putida KT2440. Microb Cell Fact (2011) 1.31

Generation of multicellular tumor spheroids by the hanging-drop method. Methods Mol Med (2007) 1.26

Metabolic flux analysis in mammalian cell culture. Metab Eng (2009) 1.24

Correlation between TCA cycle flux and glucose uptake rate during respiro-fermentative growth of Saccharomyces cerevisiae. Microbiology (2009) 1.22

Deep sequencing-based transcriptome analysis of Plutella xylostella larvae parasitized by Diadegma semiclausum. BMC Genomics (2011) 1.18

AlgaGEM--a genome-scale metabolic reconstruction of algae based on the Chlamydomonas reinhardtii genome. BMC Genomics (2011) 1.15

On the reconstruction of the Mus musculus genome-scale metabolic network model. Genome Inform (2008) 1.13

Design of artificial myocardial microtissues. Tissue Eng (2004) 1.12

Ultra-high-yield manufacture of red blood cells from hematopoietic stem cells. Tissue Eng Part C Methods (2011) 1.09

Grand challenge commentary: Chassis cells for industrial biochemical production. Nat Chem Biol (2010) 1.07

Metabolic and transcriptional response to cofactor perturbations in Escherichia coli. J Biol Chem (2010) 1.05

IL10 and IL12B polymorphisms each influence IL-12p70 secretion by dendritic cells in response to LPS. Immunol Cell Biol (2006) 1.05

Oxygen- and glucose-dependent regulation of central carbon metabolism in Pichia anomala. Appl Environ Microbiol (2004) 1.05

Systems biology: Hypothesis-driven omics integration. Nat Chem Biol (2010) 1.05

Carbon metabolism limits recombinant protein production in Pichia pastoris. Biotechnol Bioeng (2011) 1.04

Metabolic and practical considerations on microbial electrosynthesis. Curr Opin Biotechnol (2011) 1.03

Blood cell manufacture: current methods and future challenges. Trends Biotechnol (2009) 1.03

Chemical and biological single cell analysis. Curr Opin Biotechnol (2010) 1.03

Evolution of the hyaluronic acid synthesis (has) operon in Streptococcus zooepidemicus and other pathogenic streptococci. J Mol Evol (2008) 1.02

Quantitative physiology of Pichia pastoris during glucose-limited high-cell density fed-batch cultivation for recombinant protein production. Biotechnol Bioeng (2010) 1.00

Knock-in/Knock-out (KIKO) vectors for rapid integration of large DNA sequences, including whole metabolic pathways, onto the Escherichia coli chromosome at well-characterised loci. Microb Cell Fact (2013) 0.98

Hanging-drop multicellular spheroids as a model of tumour angiogenesis. Angiogenesis (2004) 0.98

Stable production of hyaluronic acid in Streptococcus zooepidemicus chemostats operated at high dilution rate. Biotechnol Bioeng (2005) 0.97

Alleviating monoterpene toxicity using a two-phase extractive fermentation for the bioproduction of jet fuel mixtures in Saccharomyces cerevisiae. Biotechnol Bioeng (2012) 0.96

NADH availability limits asymmetric biocatalytic epoxidation in a growing recombinant Escherichia coli strain. Appl Environ Microbiol (2008) 0.96

Quantification of metabolic limitations during recombinant protein production in Escherichia coli. J Biotechnol (2011) 0.95

Engineering yield and rate of reductive biotransformation in Escherichia coli by partial cyclization of the pentose phosphate pathway and PTS-independent glucose transport. Appl Microbiol Biotechnol (2011) 0.91

Development of chemically defined medium for Mannheimia succiniciproducens based on its genome sequence. Appl Microbiol Biotechnol (2008) 0.91

Reconstruction of the Saccharopolyspora erythraea genome-scale model and its use for enhancing erythromycin production. Antonie Van Leeuwenhoek (2012) 0.91

The Envirostat - a new bioreactor concept. Lab Chip (2008) 0.90

Amplifying the cellular reduction potential of Streptococcus zooepidemicus. J Biotechnol (2003) 0.90

Glycerophospholipid profiling by high-performance liquid chromatography/mass spectrometry using exact mass measurements and multi-stage mass spectrometric fragmentation experiments in parallel. Rapid Commun Mass Spectrom (2009) 0.90

Saccharopolyspora erythraea's genome is organised in high-order transcriptional regions mediated by targeted degradation at the metabolic switch. BMC Genomics (2013) 0.90

Re-annotation of the Saccharopolyspora erythraea genome using a systems biology approach. BMC Genomics (2013) 0.88

Response of Pseudomonas putida KT2440 to increased NADH and ATP demand. Appl Environ Microbiol (2011) 0.88

Quantitative analysis of intracellular sugar phosphates and sugar nucleotides in encapsulated streptococci using HPAEC-PAD. Biotechnol J (2009) 0.88

A transferable sucrose utilization approach for non-sucrose-utilizing Escherichia coli strains. Biotechnol Adv (2011) 0.87

Metabolite profiling of CHO cells with different growth characteristics. Biotechnol Bioeng (2012) 0.87

Mammalian cells as biopharmaceutical production hosts in the age of omics. Biotechnol J (2011) 0.87

Flux balance analysis of CHO cells before and after a metabolic switch from lactate production to consumption. Biotechnol Bioeng (2012) 0.87

Complete genome sequence of Pseudomonas sp. strain VLB120 a solvent tolerant, styrene degrading bacterium, isolated from forest soil. J Biotechnol (2013) 0.87

Production of polyhydroxybutyrate in sugarcane. Plant Biotechnol J (2007) 0.86

A multi-omics analysis of recombinant protein production in Hek293 cells. PLoS One (2012) 0.86

Enhanced polyhydroxybutyrate production in transgenic sugarcane. Plant Biotechnol J (2012) 0.86

Metabolic flux analysis of a phenol producing mutant of Pseudomonas putida S12: verification and complementation of hypotheses derived from transcriptomics. J Biotechnol (2009) 0.86

Functional proteomic analysis of GS-NS0 murine myeloma cell lines with varying recombinant monoclonal antibody production rate. Biotechnol Bioeng (2006) 0.85

Physiological and transcriptional responses of Saccharomyces cerevisiae to d-limonene show changes to the cell wall but not to the plasma membrane. Appl Environ Microbiol (2013) 0.85

Genome scale transcriptomics of baculovirus-insect interactions. Viruses (2013) 0.85

Engineered quorum sensing using pheromone-mediated cell-to-cell communication in Saccharomyces cerevisiae. ACS Synth Biol (2013) 0.85

2,2-Diphenyl-1-picrylhydrazyl as a screening tool for recombinant monoterpene biosynthesis. Microb Cell Fact (2013) 0.85

Deletion of cscR in Escherichia coli W improves growth and poly-3-hydroxybutyrate (PHB) production from sucrose in fed batch culture. J Biotechnol (2011) 0.85

Monocyte-derived DC primed with TLR agonists secrete IL-12p70 in a CD40-dependent manner under hyperthermic conditions. J Immunother (2006) 0.84

Subtoxic product levels limit the epoxidation capacity of recombinant E. coli by increasing microbial energy demands. J Biotechnol (2012) 0.84

Engineering and adaptive evolution of Escherichia coli for D-lactate fermentation reveals GatC as a xylose transporter. Metab Eng (2012) 0.84

Increased biomass yield of Lactococcus lactis during energetically limited growth and respiratory conditions. Biotechnol Appl Biochem (2008) 0.84

Understanding plasmid effect on hyaluronic acid molecular weight produced by Streptococcus equi subsp. zooepidemicus. Metab Eng (2009) 0.83

The glycerophospholipid inventory of Pseudomonas putida is conserved between strains and enables growth condition-related alterations. Microb Biotechnol (2011) 0.83

HR index--a simple method for the prediction of oxygen uptake. Med Sci Sports Exerc (2011) 0.83

Short-term exposure of umbilical cord blood CD34+ cells to granulocyte-macrophage colony-stimulating factor early in culture improves ex vivo expansion of neutrophils. Cytotherapy (2010) 0.83

In vitro production of Helicoverpa baculovirus biopesticides--automated selection of insect cell clones for manufacturing and systems biology studies. J Virol Methods (2011) 0.83

Molecular control of sucrose utilization in Escherichia coli W, an efficient sucrose-utilizing strain. Appl Environ Microbiol (2012) 0.83

Generation and maturation of dendritic cells for clinical application under serum-free conditions. J Immunother (2005) 0.82

Ethanol reduces mitochondrial membrane integrity and thereby impacts carbon metabolism of Saccharomyces cerevisiae. FEMS Yeast Res (2012) 0.82

Importance of virus-medium interactions on the biological activity of wild-type Heliothine nucleopolyhedroviruses propagated via suspension insect cell cultures. J Virol Methods (2006) 0.82

Surface-bound stem cell factor and the promotion of hematopoietic cell expansion. Biomaterials (2009) 0.82

Development of sucrose-utilizing Escherichia coli K-12 strain by cloning β-fructofuranosidases and its application for L-threonine production. Appl Microbiol Biotechnol (2010) 0.82

PATHLOGIC-S: a scalable Boolean framework for modelling cellular signalling. PLoS One (2012) 0.81

Kinetic characterization of the group II Helicoverpa armigera nucleopolyhedrovirus propagated in suspension cell cultures: implications for development of a biopesticides production process. Biotechnol Prog (2011) 0.81

Genome scale analysis of differential mRNA expression of Helicoverpa zea insect cells infected with a H. armigera baculovirus. Virology (2013) 0.81

The ascorbic acid paradox. Biochem Biophys Res Commun (2010) 0.81

Picoliter nDEP traps enable time-resolved contactless single bacterial cell analysis in controlled microenvironments. Lab Chip (2013) 0.81

Dual gene expression cassette vectors with antibiotic selection markers for engineering in Saccharomyces cerevisiae. Microb Cell Fact (2013) 0.81

Ligand-receptor interactions and membrane structure investigated by AFM and time-resolved fluorescence microscopy. J Mol Recognit (2007) 0.81

Proline availability regulates proline-4-hydroxylase synthesis and substrate uptake in proline-hydroxylating recombinant Escherichia coli. Appl Environ Microbiol (2013) 0.81

Chemical inhibition of acetyl coenzyme A carboxylase as a strategy to increase polyhydroxybutyrate yields in transgenic sugarcane. Plant Biotechnol J (2013) 0.81

Identification of an endo-1,4-beta-xylanase of Ustilago maydis. BMC Biotechnol (2013) 0.80

Synthesis and characterization of alginate/poly-L-ornithine/alginate microcapsules for local immunosuppression. J Microencapsul (2008) 0.80

Spatio-temporal characterization of polyhydroxybutyrate accumulation in sugarcane. Plant Biotechnol J (2007) 0.80

Towards real time analysis of protein secretion from single cells. Lab Chip (2009) 0.80

Single cell analysis reveals unexpected growth phenotype of S. cerevisiae. Cytometry A (2009) 0.80

Simple enzymatic procedure for L-carnosine synthesis: whole-cell biocatalysis and efficient biocatalyst recycling. Microb Biotechnol (2009) 0.80

Clinical scale ex vivo manufacture of neutrophils from hematopoietic progenitor cells. Biotechnol Bioeng (2009) 0.80

Insight into hyaluronic acid molecular weight control. Appl Microbiol Biotechnol (2014) 0.80

Extracting reaction networks from databases-opening Pandora's box. Brief Bioinform (2013) 0.79

Plant genome-scale modeling and implementation. Methods Mol Biol (2014) 0.79

Absolute counting of neutrophils in whole blood using flow cytometry. Cytometry A (2014) 0.79

High temperature stimulates acetic acid accumulation and enhances the growth inhibition and ethanol production by Saccharomyces cerevisiae under fermenting conditions. Appl Microbiol Biotechnol (2014) 0.79

Membrane bioreactors enhance microenvironmental conditioning and tissue development. Tissue Eng Part C Methods (2010) 0.79

Metabolic engineering: from retrofitting to green field. Nat Chem Biol (2011) 0.78

Bioreactor for blood product production. Cell Transplant (2012) 0.78

Transcriptome sequencing of and microarray development for a Helicoverpa zea cell line to investigate in vitro insect cell-baculovirus interactions. PLoS One (2012) 0.78