Published in Methods Cell Biol on January 01, 2004
Direct observation of individual endogenous protein complexes in situ by proximity ligation. Nat Methods (2006) 12.63
Multiplexed genotyping with sequence-tagged molecular inversion probes. Nat Biotechnol (2003) 7.02
Protein detection using proximity-dependent DNA ligation assays. Nat Biotechnol (2002) 6.05
Multigene amplification and massively parallel sequencing for cancer mutation discovery. Proc Natl Acad Sci U S A (2007) 3.93
The F-box protein Skp2 participates in c-Myc proteosomal degradation and acts as a cofactor for c-Myc-regulated transcription. Mol Cell (2003) 3.87
c-Myc associates with ribosomal DNA and activates RNA polymerase I transcription. Nat Cell Biol (2005) 3.79
Multiplex amplification enabled by selective circularization of large sets of genomic DNA fragments. Nucleic Acids Res (2005) 3.59
BLUEPRINT to decode the epigenetic signature written in blood. Nat Biotechnol (2012) 3.24
Characterizing proteins and their interactions in cells and tissues using the in situ proximity ligation assay. Methods (2008) 3.16
Somatically mutated Ig V(H)3-21 genes characterize a new subset of chronic lymphocytic leukemia. Blood (2002) 3.00
Cardiovascular disease and diabetes in the Northern Sweden Health and Disease Study Cohort - evaluation of risk factors and their interactions. Scand J Public Health Suppl (2003) 2.72
In situ genotyping individual DNA molecules by target-primed rolling-circle amplification of padlock probes. Nat Methods (2004) 2.40
Duplication of FGF3, FGF4, FGF19 and ORAOV1 causes hair ridge and predisposition to dermoid sinus in Ridgeback dogs. Nat Genet (2007) 2.33
Cytokine detection by antibody-based proximity ligation. Proc Natl Acad Sci U S A (2004) 2.29
In situ detection and genotyping of individual mRNA molecules. Nat Methods (2010) 2.29
In situ sequencing for RNA analysis in preserved tissue and cells. Nat Methods (2013) 2.13
In situ detection of phosphorylated platelet-derived growth factor receptor beta using a generalized proximity ligation method. Mol Cell Proteomics (2007) 2.10
Polymorphism in the P2X7 receptor gene and survival in chronic lymphocytic leukaemia. Lancet (2002) 1.97
A new perspective: molecular motifs on oxidized LDL, apoptotic cells, and bacteria are targets for chronic lymphocytic leukemia antibodies. Blood (2008) 1.93
Subsets with restricted immunoglobulin gene rearrangement features indicate a role for antigen selection in the development of chronic lymphocytic leukemia. Blood (2004) 1.77
Flow cytometric in situ proximity ligation analyses of protein interactions and post-translational modification of the epidermal growth factor receptor family. Cytometry A (2009) 1.73
Proximity ligation assays: a recent addition to the proteomics toolbox. Expert Rev Proteomics (2010) 1.70
Digital quantification using amplified single-molecule detection. Nat Methods (2006) 1.66
Targeted enrichment of genomic DNA regions for next-generation sequencing. Brief Funct Genomics (2011) 1.63
Parallel visualization of multiple protein complexes in individual cells in tumor tissue. Mol Cell Proteomics (2013) 1.60
Circle-to-circle amplification for precise and sensitive DNA analysis. Proc Natl Acad Sci U S A (2004) 1.59
Phosphorylation of inositol 1,4,5-trisphosphate receptors by protein kinase B/Akt inhibits Ca2+ release and apoptosis. Proc Natl Acad Sci U S A (2008) 1.59
Endothelial cell migration in stable gradients of vascular endothelial growth factor A and fibroblast growth factor 2: effects on chemotaxis and chemokinesis. J Biol Chem (2008) 1.58
Countrywide estimates of forest variables using satellite data and field data from the National Forest Inventory. Ambio (2003) 1.57
WRAP53 is essential for Cajal body formation and for targeting the survival of motor neuron complex to Cajal bodies. PLoS Biol (2010) 1.57
Novel and highly recurrent chromosomal alterations in Sézary syndrome. Cancer Res (2008) 1.51
Parallel gene analysis with allele-specific padlock probes and tag microarrays. Nucleic Acids Res (2003) 1.48
PieceMaker: selection of DNA fragments for selector-guided multiplex amplification. Nucleic Acids Res (2005) 1.46
Real-time monitoring of rolling-circle amplification using a modified molecular beacon design. Nucleic Acids Res (2002) 1.39
Targeted resequencing of candidate genes using selector probes. Nucleic Acids Res (2010) 1.37
VEGF receptor 2/-3 heterodimers detected in situ by proximity ligation on angiogenic sprouts. EMBO J (2010) 1.37
Adipose tissue dominates chronic arm lymphedema following breast cancer: an analysis using volume rendered CT images. Lymphat Res Biol (2006) 1.33
Detection of antigen interactions ex vivo by proximity ligation assay: endogenous dopamine D2-adenosine A2A receptor complexes in the striatum. Biotechniques (2011) 1.27
Nitrous oxide production in a forest soil at low temperatures - processes and environmental controls. FEMS Microbiol Ecol (2004) 1.23
ProbeMaker: an extensible framework for design of sets of oligonucleotide probes. BMC Bioinformatics (2005) 1.23
Organic material: the primary control on mercury methylation and ambient methyl mercury concentrations in estuarine sediments. Environ Sci Technol (2006) 1.22
Quality of life and burden in parents of outpatients with schizophrenia. Soc Psychiatry Psychiatr Epidemiol (2005) 1.21
A dual-tag microarray platform for high-performance nucleic acid and protein analyses. Nucleic Acids Res (2008) 1.20
Identification of new cancer biomarkers based on aberrant mucin glycoforms by in situ proximity ligation. J Cell Mol Med (2012) 1.19
The effects of forestry on Hg bioaccumulation in nemoral/boreal waters and recommendations for good silvicultural practice. Ambio (2009) 1.18
Effect of monitors on approximal caries detection in digital radiographs--standard versus precalibrated DICOM part 14 displays: an in vitro study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2009) 1.18
Transcriptional profiling of human glioblastoma vessels indicates a key role of VEGF-A and TGFβ2 in vascular abnormalization. J Pathol (2012) 1.16
Selection of dental materials and longevity of replaced restorations in Public Dental Health clinics in northern Sweden. J Dent (2009) 1.16
Making ends meet in genetic analysis using padlock probes. Hum Mutat (2002) 1.15
Microarray-based molecular detection of foot-and-mouth disease, vesicular stomatitis and swine vesicular disease viruses, using padlock probes. J Virol Methods (2007) 1.14
Lateral-flow and up-converting phosphor reporters to detect single-stranded nucleic acids in a sandwich-hybridization assay. Anal Biochem (2003) 1.12
DNA repair genes are selectively mutated in diffuse large B cell lymphomas. J Exp Med (2013) 1.12
High content screening for inhibitors of protein interactions and post-translational modifications in primary cells by proximity ligation. Mol Cell Proteomics (2009) 1.10
Visualising individual sequence-specific protein-DNA interactions in situ. N Biotechnol (2011) 1.10
Increasing the dynamic range of in situ PLA. Nat Methods (2011) 1.08
Proximity ligation assays for sensitive and specific protein analyses. Anal Biochem (2005) 1.07
Analyzing genes using closing and replicating circles. Trends Biotechnol (2005) 1.06
Molecular tools for a molecular medicine: analyzing genes, transcripts and proteins using padlock and proximity probes. J Mol Recognit (2004) 1.05
MUC2 mucin is a major carrier of the cancer-associated sialyl-Tn antigen in intestinal metaplasia and gastric carcinomas. Glycobiology (2009) 1.05
Functional interaction of DYX1C1 with estrogen receptors suggests involvement of hormonal pathways in dyslexia. Hum Mol Genet (2009) 1.04
Detection of rolling circle amplified DNA molecules using probe-tagged magnetic nanobeads in a portable AC susceptometer. Biosens Bioelectron (2011) 1.03
In situ proximity ligation assay for microscopy and flow cytometry. Curr Protoc Cytom (2011) 1.01
Analysis of protein interactions in situ by proximity ligation assays. Curr Top Microbiol Immunol (2014) 1.01
Mutated VH genes and preferential VH3-21 use define new subsets of mantle cell lymphoma. Blood (2003) 1.00
Homogeneous detection of single rolling circle replication products. Anal Chem (2004) 1.00
Analysis of T-cell receptor V beta gene repertoires after immune stimulation and in malignancy by use of padlock probes and microarrays. Clin Chem (2005) 1.00
In situ detection of individual mRNA molecules and protein complexes or post-translational modifications using padlock probes combined with the in situ proximity ligation assay. Nat Protoc (2013) 0.99
Is frequent attendance a persistent characteristic of a patient? Repeat studies of attendance pattern at the family practitioner. Scand J Prim Health Care (2004) 0.99
Sensitive molecular diagnostics using volume-amplified magnetic nanobeads. Nano Lett (2008) 0.98
Frequency, type and factors associated with the use of complementary and alternative medicine in patients with Parkinson's disease at a neurological outpatient clinic. Parkinsonism Relat Disord (2010) 0.98
Protein tag-mediated conjugation of oligonucleotides to recombinant affinity binders for proximity ligation. N Biotechnol (2012) 0.97
MLGA--a rapid and cost-efficient assay for gene copy-number analysis. Nucleic Acids Res (2007) 0.97
Coaching interprofessional health care improvement teams: the coachee, the coach and the leader perspectives. J Nurs Manag (2013) 0.97
A sense of closeness: protein detection by proximity ligation. Curr Opin Biotechnol (2003) 0.96
Organic matter control of mercury and lead toxicity in mor layers. Ecotoxicol Environ Saf (2010) 0.96