Published in Differentiation on October 01, 2004
Desmoglein 4 is regulated by transcription factors implicated in hair shaft differentiation. Differentiation (2009) 0.86
Effects of parity and serum prolactin levels on the incidence and regression of DMBA-induced tumors in OFA hr/hr rats. Biomed Res Int (2014) 0.78
Genome-wide association study in alopecia areata implicates both innate and adaptive immunity. Nature (2010) 2.85
The gene encoding R-spondin 4 (RSPO4), a secreted protein implicated in Wnt signaling, is mutated in inherited anonychia. Nat Genet (2006) 2.81
PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+ T cells. J Exp Med (2012) 2.58
Desmoglein 4 in hair follicle differentiation and epidermal adhesion: evidence from inherited hypotrichosis and acquired pemphigus vulgaris. Cell (2003) 2.06
Disruption of P2RY5, an orphan G protein-coupled receptor, underlies autosomal recessive woolly hair. Nat Genet (2008) 2.00
Mutations in the lipase H gene underlie autosomal recessive woolly hair/hypotrichosis. J Invest Dermatol (2008) 1.96
Epidermal terminal differentiation depends on B lymphocyte-induced maturation protein-1. Proc Natl Acad Sci U S A (2007) 1.85
Germline fumarate hydratase mutations in families with multiple cutaneous and uterine leiomyomata. J Invest Dermatol (2003) 1.72
Amelioration of epidermolysis bullosa by transfer of wild-type bone marrow cells. Blood (2008) 1.62
Clinical and pathologic correlations in genetically distinct forms of atrichia. Arch Dermatol (2003) 1.57
Genomewide scan for linkage reveals evidence of several susceptibility loci for alopecia areata. Am J Hum Genet (2007) 1.55
Generation of keratinocytes from normal and recessive dystrophic epidermolysis bullosa-induced pluripotent stem cells. Proc Natl Acad Sci U S A (2011) 1.54
Hairless and the polyamine putrescine form a negative regulatory loop in the epidermis. Exp Dermatol (2013) 1.39
Clinical and molecular diagnostic criteria of congenital atrichia with papular lesions. J Invest Dermatol (2002) 1.35
APCDD1 is a novel Wnt inhibitor mutated in hereditary hypotrichosis simplex. Nature (2010) 1.35
Structural and functional consequences of loricrin mutations in human loricrin keratoderma (Vohwinkel syndrome with ichthyosis). J Invest Dermatol (2004) 1.24
P-cadherin is a p63 target gene with a crucial role in the developing human limb bud and hair follicle. Development (2008) 1.20
Hair follicle stem cells. J Investig Dermatol Symp Proc (2003) 1.19
The Wnt inhibitor, Dickkopf 4, is induced by canonical Wnt signaling during ectodermal appendage morphogenesis. Dev Biol (2007) 1.18
Identification of two novel human acyl-CoA wax alcohol acyltransferases: members of the diacylglycerol acyltransferase 2 (DGAT2) gene superfamily. J Biol Chem (2005) 1.17
Activation of Notch1 in the hair follicle leads to cell-fate switch and Mohawk alopecia. Differentiation (2004) 1.17
Compound heterozygosity for non-sense and mis-sense mutations in desmoplakin underlies skin fragility/woolly hair syndrome. J Invest Dermatol (2002) 1.15
Desmoglein 4 is expressed in highly differentiated keratinocytes and trichocytes in human epidermis and hair follicle. Differentiation (2006) 1.14
A position effect on TRPS1 is associated with Ambras syndrome in humans and the Koala phenotype in mice. Hum Mol Genet (2008) 1.14
Founder mutations in the lipase h gene in families with autosomal recessive woolly hair/hypotrichosis. J Invest Dermatol (2009) 1.13
Conditional activin receptor type 1B (Acvr1b) knockout mice reveal hair loss abnormality. J Invest Dermatol (2010) 1.09
The effect of inbreeding on the distribution of compound heterozygotes: a lesson from Lipase H mutations in autosomal recessive woolly hair/hypotrichosis. Hum Hered (2009) 1.09
Identification of C7orf11 (TTDN1) gene mutations and genetic heterogeneity in nonphotosensitive trichothiodystrophy. Am J Hum Genet (2005) 1.07
Niche crosstalk: intercellular signals at the hair follicle. Cell (2011) 1.06
Nonsense mutations in the hairless gene underlie APL in five families of Pakistani origin. J Dermatol Sci (2007) 1.06
Delineation of diversified desmoglein distribution in stratified squamous epithelia: implications in diseases. Exp Dermatol (2006) 1.06
Whole-exome sequencing in a single proband reveals a mutation in the CHST8 gene in autosomal recessive peeling skin syndrome. Genomics (2012) 1.04
Epidermal expression of the truncated prelamin A causing Hutchinson-Gilford progeria syndrome: effects on keratinocytes, hair and skin. Hum Mol Genet (2008) 1.03
Novel molecular therapies for heritable skin disorders. J Invest Dermatol (2011) 1.03
Targeted ablation of Arnt in mouse epidermis results in profound defects in desquamation and epidermal barrier function. J Cell Sci (2006) 1.03
Generation of 3D skin equivalents fully reconstituted from human induced pluripotent stem cells (iPSCs). PLoS One (2013) 1.03
Genetic basis of alopecia areata: a roadmap for translational research. Dermatol Clin (2012) 1.03
KGF and EGF signalling block hair follicle induction and promote interfollicular epidermal fate in developing mouse skin. Development (2009) 1.03
Prenatal diagnosis for epidermolysis bullosa: a study of 144 consecutive pregnancies at risk. Prenat Diagn (2003) 1.02
Microenvironmental reprogramming by three-dimensional culture enables dermal papilla cells to induce de novo human hair-follicle growth. Proc Natl Acad Sci U S A (2013) 1.02
Mutations in R-spondin 4 (RSPO4) underlie inherited anonychia. J Invest Dermatol (2007) 1.01
Mutations in the desmoglein 4 gene underlie localized autosomal recessive hypotrichosis with monilethrix hairs and congenital scalp erosions. J Invest Dermatol (2006) 1.00
Broken hearts, woolly hair, and tattered skin: when desmosomal adhesion goes awry. Curr Opin Cell Biol (2007) 0.99
A mouse model of uterine leiomyosarcoma. Am J Pathol (2004) 0.99
Biology and genetics of hair. Annu Rev Genomics Hum Genet (2010) 0.97
The hairless promoter is differentially regulated by thyroid hormone in keratinocytes and neuroblastoma cells. Exp Dermatol (2004) 0.96
De novo mutations in monilethrix. Exp Dermatol (2003) 0.96
Transcriptional profiling of developing mouse epidermis reveals novel patterns of coordinated gene expression. Dev Dyn (2007) 0.96
Autosomal-dominant woolly hair resulting from disruption of keratin 74 (KRT74), a potential determinant of human hair texture. Am J Hum Genet (2010) 0.95
Mutations in the LIPH gene in three Japanese families with autosomal recessive woolly hair/hypotrichosis. J Dermatol Sci (2009) 0.95
Hereditary leukonychia, or porcelain nails, resulting from mutations in PLCD1. Am J Hum Genet (2011) 0.95
Loss of hairless confers susceptibility to UVB-induced tumorigenesis via disruption of NF-kappaB signaling. PLoS One (2012) 0.94
Multiple cutaneous and uterine leiomyomas: refinement of the genetic locus for multiple cutaneous and uterine leiomyomas on chromosome 1q42.3-43. J Invest Dermatol (2002) 0.93
The WNT signalling modulator, Wise, is expressed in an interaction-dependent manner during hair-follicle cycling. J Invest Dermatol (2004) 0.92
Trps1 and its target gene Sox9 regulate epithelial proliferation in the developing hair follicle and are associated with hypertrichosis. PLoS Genet (2012) 0.92
Genome-wide linkage analysis of an autosomal recessive hypotrichosis identifies a novel P2RY5 mutation. Genomics (2008) 0.92
ARNT controls the expression of epidermal differentiation genes through HDAC- and EGFR-dependent pathways. J Cell Sci (2012) 0.92
Germline fumarate hydratase mutations and evidence for a founder mutation underlying multiple cutaneous and uterine leiomyomata. J Am Acad Dermatol (2005) 0.91
Evidence for extensive locus heterogeneity in Naxos disease. J Invest Dermatol (2002) 0.91
Trps1 activates a network of secreted Wnt inhibitors and transcription factors crucial to vibrissa follicle morphogenesis. Development (2011) 0.90
'Designer' tumors in mice. Oncogene (2004) 0.90
Atrichia with papular lesions resulting from mutations in the rhesus macaque (Macaca mulatta) hairless gene. Lab Anim (2002) 0.90
Reprogramming of human hair follicle dermal papilla cells into induced pluripotent stem cells. J Invest Dermatol (2012) 0.90
Differential structural properties and expression patterns suggest functional significance for multiple mouse desmoglein 1 isoforms. Differentiation (2004) 0.89
Smad4-dependent desmoglein-4 expression contributes to hair follicle integrity. Dev Biol (2008) 0.89
Genetics of structural hair disorders. J Invest Dermatol (2012) 0.89
The role of BMP signalling in the control of ID3 expression in the hair follicle. Exp Dermatol (2004) 0.88
The spectrum of hair loss in patients with mycosis fungoides and Sézary syndrome. J Am Acad Dermatol (2010) 0.88
Expression patterns of the transcription factor AP-2alpha during hair follicle morphogenesis and cycling. J Invest Dermatol (2003) 0.88
Compound heterozygous mutations in the hairless gene in atrichia with papular lesions. J Invest Dermatol (2003) 0.88
Dynamic expression of the zinc-finger transcription factor Trps1 during hair follicle morphogenesis and cycling. Gene Expr Patterns (2007) 0.88
Mutations in the keratin 85 (KRT85/hHb5) gene underlie pure hair and nail ectodermal dysplasia. J Invest Dermatol (2009) 0.88
Position effect on FGF13 associated with X-linked congenital generalized hypertrichosis. Proc Natl Acad Sci U S A (2013) 0.88
A nonsense mutation in the desmoglein 1 gene underlies striate keratoderma. Exp Dermatol (2003) 0.87
Autosomal recessive woolly hair with hypotrichosis caused by a novel homozygous mutation in the P2RY5 gene. Exp Dermatol (2008) 0.87
Striate palmoplantar keratoderma resulting from a frameshift mutation in the desmoglein 1 gene. J Dermatol Sci (2006) 0.87
Localized autosomal recessive hypotrichosis due to a frameshift mutation in the desmoglein 4 gene exhibits extensive phenotypic variability within a Pakistani family. J Invest Dermatol (2007) 0.87
Health-Related Quality of Life (HRQoL) in alopecia areata patients-a secondary analysis of the National Alopecia Areata Registry Data. J Investig Dermatol Symp Proc (2013) 0.87
Pumpless microfluidic platform for drug testing on human skin equivalents. Lab Chip (2015) 0.86
Desmoglein 4 is regulated by transcription factors implicated in hair shaft differentiation. Differentiation (2009) 0.86
Hairless contains a novel nuclear matrix targeting signal and associates with histone deacetylase 3 in nuclear speckles. Differentiation (2004) 0.86
Atrichia with papular lesions resulting from compound heterozygous mutations in the hairless gene: A lesson for differential diagnosis of alopecia universalis. J Am Acad Dermatol (2002) 0.86
Bone marrow stem cell therapy for recessive dystrophic epidermolysis bullosa. Dermatol Clin (2010) 0.85
Mutations in the SLURP-1 gene underlie Mal de Meleda in three Pakistani families. J Dermatol Sci (2009) 0.85
A recurrent intragenic deletion in the desmoglein 4 gene underlies localized autosomal recessive hypotrichosis. J Invest Dermatol (2004) 0.85
Hairless is a histone H3K9 demethylase. FASEB J (2013) 0.84
Mutations in the hairless gene underlie APL in three families of Pakistani origin. J Dermatol Sci (2008) 0.84
Identification of a novel splice site mutation in the human hairless gene underlying atrichia with papular lesions. Eur J Dermatol (2005) 0.84
Novel compound heterozygous nonsense mutations in the hairless gene causing atrichia with papular lesions. J Dermatol Sci (2005) 0.83
Hypoxia-mediated control of HIF/ARNT machinery in epidermal keratinocytes. Biochim Biophys Acta (2010) 0.83
Autosomal recessive gingival hyperplasia and dental anomalies caused by a 29-base pair duplication in the FAM20A gene. J Hum Genet (2013) 0.83
Interaction of hairless and thyroid hormone receptor is not involved in the pathogenesis of atrichia with papular lesions. Exp Dermatol (2004) 0.83
The lanceolate hair rat phenotype results from a missense mutation in a calcium coordinating site of the desmoglein 4 gene. Genomics (2004) 0.83
Nothing but skin and bone. J Clin Invest (2006) 0.82