Published in Diabet Med on January 01, 2005
Pharmacologic ascorbic acid concentrations selectively kill cancer cells: action as a pro-drug to deliver hydrogen peroxide to tissues. Proc Natl Acad Sci U S A (2005) 3.30
Interstitial glucose concentration in insulin-resistant human skeletal muscle: influence of one bout of exercise and of local perfusion with insulin or vanadate. Eur J Appl Physiol (2008) 0.75
The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase. Proc Natl Acad Sci U S A (1968) 6.96
Adenosine regulates via two different types of receptors, the accumulation of cyclic AMP in cultured brain cells. J Neurochem (1979) 5.92
The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism. EMBO J (1999) 5.47
Microsomal heme oxygenase. Characterization of the enzyme. J Biol Chem (1969) 5.35
The hydrogen hypothesis for the first eukaryote. Nature (1998) 5.26
Lymphocyte apoptosis induced by CD95 (APO-1/Fas) ligand-expressing tumor cells--a mechanism of immune evasion? Nat Med (1996) 5.09
Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Nature (1999) 5.03
Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis. Cell (1998) 4.77
A modified procedure for the rapid preparation of efficiently transporting vesicles from small intestinal brush border membranes. Their use in investigating some properties of D-glucose and choline transport systems. Biochim Biophys Acta (1978) 4.66
Complementation by the protein tyrosine kinase JAK2 of a mutant cell line defective in the interferon-gamma signal transduction pathway. Nature (1993) 4.20
Analysis of the induction of general stress proteins of Bacillus subtilis. Microbiology (1994) 4.16
The structure of the Antennapedia homeodomain determined by NMR spectroscopy in solution: comparison with prokaryotic repressors. Cell (1989) 4.13
Peroxisome proliferator-activated receptor alpha target genes. Cell Mol Life Sci (2004) 3.86
High-frequency mutagenesis of human cells and characterization of a mutant unresponsive to both alpha and gamma interferons. Proc Natl Acad Sci U S A (1991) 3.83
Inhibition of the Abl protein-tyrosine kinase in vitro and in vivo by a 2-phenylaminopyrimidine derivative. Cancer Res (1996) 3.77
Lysosomes of the arterial wall. I. Isolation and subcellular fractionation of cells from normal rabbit aorta. J Exp Med (1972) 3.73
Protein--DNA contacts in the structure of a homeodomain--DNA complex determined by nuclear magnetic resonance spectroscopy in solution. EMBO J (1990) 3.50
Epigenetic inactivation of microRNA gene hsa-mir-9-1 in human breast cancer. J Pathol (2008) 3.18
Transient accumulation of potassium glutamate and its replacement by trehalose during adaptation of growing cells of Escherichia coli K-12 to elevated sodium chloride concentrations. Arch Microbiol (1988) 3.12
CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation. EMBO J (1998) 3.06
The interaction with DNA of wild-type and mutant fushi tarazu homeodomains. EMBO J (1990) 2.97
Sleeve gastrectomy and gastric banding: effects on plasma ghrelin levels. Obes Surg (2005) 2.91
Recent observations on the serology of syphilis. Br J Vener Dis (1980) 2.90
Hydrogenosome, a cytoplasmic organelle of the anaerobic flagellate Tritrichomonas foetus, and its role in pyruvate metabolism. J Biol Chem (1973) 2.90
Regulation of sigmaB-dependent transcription of sigB and asp23 in two different Staphylococcus aureus strains. Mol Gen Genet (1999) 2.62
Hepatocanalicular bile salt export pump deficiency in patients with progressive familial intrahepatic cholestasis. Gastroenterology (1999) 2.61
DNA binding properties of the purified Antennapedia homeodomain. Proc Natl Acad Sci U S A (1990) 2.60
A novel sec-independent periplasmic protein translocation pathway in Escherichia coli. EMBO J (1998) 2.57
Multiple extracellular signals are required for long-term oligodendrocyte survival. Development (1993) 2.55
Role of tissue factor in embryonic blood vessel development. Nature (1996) 2.54
Universal digital quantum simulation with trapped ions. Science (2011) 2.49
In vitro translocation of bacterial proteins across the plasma membrane of Escherichia coli. Proc Natl Acad Sci U S A (1984) 2.46
Nuclear magnetic resonance solution structure of the fushi tarazu homeodomain from Drosophila and comparison with the Antennapedia homeodomain. J Mol Biol (1994) 2.43
Lymphocytic and granulomatous hypophysitis: experience with nine cases. Neurosurgery (1997) 2.37
Protein export in Escherichia coli requires a soluble activity. Proc Natl Acad Sci U S A (1984) 2.34
The enzymatic formation of bilirubin. Ann N Y Acad Sci (1975) 2.34
Hypertension in pregnancy: clinical-pathological correlations and remote prognosis. Medicine (Baltimore) (1981) 2.33
Plasma acylation stimulating protein, adipsin and lipids in non-obese and obese populations. Eur J Clin Invest (1999) 2.32
The enzymatic catabolism of hemoglobin: stimulation of microsomal heme oxygenase by hemin. J Lab Clin Med (1970) 2.32
Tissue factor controls the balance of angiogenic and antiangiogenic properties of tumor cells in mice. J Clin Invest (1994) 2.30
Human pre-mRNA cleavage factor Im is related to spliceosomal SR proteins and can be reconstituted in vitro from recombinant subunits. Mol Cell (1998) 2.20
General and oxidative stress responses in Bacillus subtilis: cloning, expression, and mutation of the alkyl hydroperoxide reductase operon. J Bacteriol (1996) 2.20
Determination of the nuclear magnetic resonance solution structure of an Antennapedia homeodomain-DNA complex. J Mol Biol (1993) 2.20
Partial impairment of cytokine responses in Tyk2-deficient mice. Immunity (2000) 2.17
Pharmacological characterization of bosentan, a new potent orally active nonpeptide endothelin receptor antagonist. J Pharmacol Exp Ther (1994) 2.14
Informatics and medicine--from molecules to populations. Methods Inf Med (2008) 2.13
Proviral load determination of different feline immunodeficiency virus isolates using real-time polymerase chain reaction: influence of mismatches on quantification. Electrophoresis (1999) 2.09
The release of the adipocytokine visfatin is regulated by glucose and insulin. Diabetologia (2006) 2.09
Three metronidazole-resistant strains of Trichomonas vaginalis from the United States. Am J Obstet Gynecol (1980) 2.06
Retracted The effects of albumin versus hydroxyethyl starch solution on cardiorespiratory and circulatory variables in critically ill patients. Anesth Analg (1996) 2.04
Co-translocation of a periplasmic enzyme complex by a hitchhiker mechanism through the bacterial tat pathway. J Biol Chem (1999) 2.04
Antitrichomonad action, mutagenicity, and reduction of metronidazole and other nitroimidazoles. Antimicrob Agents Chemother (1976) 2.04
Expression of a stress- and starvation-induced dps/pexB-homologous gene is controlled by the alternative sigma factor sigmaB in Bacillus subtilis. J Bacteriol (1997) 2.03
Polymerase chain reaction to evaluate antiviral therapy for cytomegalovirus disease. Lancet (1991) 2.02
Enhancement of capsid gene expression: preparing the human papillomavirus type 16 major structural gene L1 for DNA vaccination purposes. J Virol (2001) 2.02
Characterization of the sigma(B) regulon in Staphylococcus aureus. J Bacteriol (2000) 2.00
High-pressure freezing of cell suspensions in cellulose capillary tubes. J Microsc (1994) 2.00
Insertion of proteins into bacterial membranes: mechanism, characteristics, and comparisons with the eucaryotic process. Microbiol Rev (1989) 1.99
In vivo biosynthesis of the vacuolar proteinases A and B in the yeast Saccharomyces cerevisiae. J Biol Chem (1982) 1.98
A bacterial secretory protein requires signal recognition particle for translocation across mammalian endoplasmic reticulum. J Biol Chem (1982) 1.97
Hepatitis B viral DNA in liver and serum of asymptomatic carriers. Proc Natl Acad Sci U S A (1982) 1.96
Catabolism of heme in vivo: comparison of the simultaneous production of bilirubin and carbon monoxide. J Clin Invest (1970) 1.96
Differentiation of follicular dendritic cells and full antibody responses require tumor necrosis factor receptor-1 signaling. J Exp Med (1996) 1.93
Retracted A derivative of staurosporine (CGP 41 251) shows selectivity for protein kinase C inhibition and in vitro anti-proliferative as well as in vivo anti-tumor activity. Int J Cancer (1989) 1.93
Retracted Selective inhibition of the platelet-derived growth factor signal transduction pathway by a protein-tyrosine kinase inhibitor of the 2-phenylaminopyrimidine class. Proc Natl Acad Sci U S A (1995) 1.93
The Fab-8 boundary defines the distal limit of the bithorax complex iab-7 domain and insulates iab-7 from initiation elements and a PRE in the adjacent iab-8 domain. Development (2000) 1.92
First steps from a two-dimensional protein index towards a response-regulation map for Bacillus subtilis. Electrophoresis (1997) 1.91
Stress proteins and cross-protection by heat shock and salt stress in Bacillus subtilis. J Gen Microbiol (1992) 1.91
In vitro drug susceptibility and doses of metronidazole required for cure in cases of refractory vaginal trichomoniasis. J Infect Dis (1986) 1.89
Secondary structure determination for the Antennapedia homeodomain by nuclear magnetic resonance and evidence for a helix-turn-helix motif. EMBO J (1988) 1.89
Specific and general stress proteins in Bacillus subtilis--a two-deimensional protein electrophoresis study. Microbiology (1997) 1.86
Multicenter trial of neo-adjuvant chemotherapy followed by extrapleural pneumonectomy in malignant pleural mesothelioma. Ann Oncol (2007) 1.85
Lysosomes in Tetrahymena pyriformis. I. Some properties and lysosomal localization of acid hydrolases. J Cell Physiol (1966) 1.83
Cold shock stress-induced proteins in Bacillus subtilis. J Bacteriol (1996) 1.83
The structure of the homeodomain and its functional implications. Trends Genet (1990) 1.82
Comparative evaluation of nine different enzyme-linked immunosorbent assays for determination of antibodies against Treponema pallidum in patients with primary syphilis. J Clin Microbiol (2000) 1.82
Foreign body reaction to meshes used for the repair of abdominal wall hernias. Eur J Surg (1999) 1.82
A comprehensive two-dimensional map of cytosolic proteins of Bacillus subtilis. Electrophoresis (2001) 1.79
Detection of hepatitis C virus in paraffin-embedded liver biopsies of patients negative for viral RNA in serum. Hepatology (1999) 1.79
The homodimeric ATP-binding cassette transporter LmrA mediates multidrug transport by an alternating two-site (two-cylinder engine) mechanism. EMBO J (2000) 1.76
Extracellular proteins of Staphylococcus aureus and the role of SarA and sigma B. Proteomics (2001) 1.75
Chromatin domain boundaries in the Bithorax complex. Cell Mol Life Sci (1998) 1.74
Enzymatic degradation of heme. Oxygenative cleavage requiring cytochrome P-450. Biochemistry (1972) 1.71
High pressure freezing comes of age. Scanning Microsc Suppl (1989) 1.71
Appraisal of the Treponema pallidum haemagglutination test. Br J Vener Dis (1973) 1.70
Increased acid and bile reflux in Barrett's esophagus compared to reflux esophagitis, and effect of proton pump inhibitor therapy. Am J Gastroenterol (2001) 1.70
Purification and partial sequencing of high-affinity progesterone-binding site(s) from porcine liver membranes. Eur J Biochem (1996) 1.70
Early-branching or fast-evolving eukaryotes? An answer based on slowly evolving positions. Proc Biol Sci (2000) 1.69
The functional integration of a polytopic membrane protein of Escherichia coli is dependent on the bacterial signal-recognition particle. Eur J Biochem (1995) 1.69
Skp, a molecular chaperone of gram-negative bacteria, is required for the formation of soluble periplasmic intermediates of outer membrane proteins. J Biol Chem (1999) 1.69
Discrimination between SRP- and SecA/SecB-dependent substrates involves selective recognition of nascent chains by SRP and trigger factor. EMBO J (2000) 1.68
Sequence close to the N-terminus of L2 protein is displayed on the surface of bovine papillomavirus type 1 virions. Virology (1997) 1.66
[Magnetic Drug Targeting--a new approach in locoregional tumor therapy with chemotherapeutic agents. Experimental animal studies]. HNO (2005) 1.64
Transient, specific and extremely rapid release of osmolytes from growing cells of Escherichia coli K-12 exposed to hypoosmotic shock. Arch Microbiol (1993) 1.64
Uptake of metronidazole and its effect on viability in trichomonads and Entamoeba invadens under anaerobic and aerobic conditions. Antimicrob Agents Chemother (1976) 1.63
Pathophysiological role of endothelin revealed by the first orally active endothelin receptor antagonist. Nature (1993) 1.62
B-type natriuretic peptide (BNP) affects the initial response to intravenous glucose: a randomised placebo-controlled cross-over study in healthy men. Diabetologia (2011) 1.61
Identification of plant-associated enterococci. J Appl Microbiol (2001) 1.60
Specificity of signaling by STAT1 depends on SH2 and C-terminal domains that regulate Ser727 phosphorylation, differentially affecting specific target gene expression. EMBO J (2001) 1.59