PD-1 blockade inhibits hematogenous spread of poorly immunogenic tumor cells by enhanced recruitment of effector T cells.

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Published in Int Immunol on December 20, 2004

Authors

Yoshiko Iwai1, Seigo Terawaki, Tasuku Honjo

Author Affiliations

1: Department of Medical Chemistry, Graduate School of Medicine, Kyoto University, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan.

Associated clinical trials:

Neoadjuvant Anti-PD-1, Nivolumab in Resectable NSCLC (NA_00092076) | NCT02259621

Neoadjuvant Immune Checkpoint Blockade in Resectable Malignant Pleural Mesothelioma | NCT03918252

Nivolumab in Biochemically Recurrent dMMR Prostate Cancer | NCT04019964

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