Published in Mol Biol Cell on January 05, 2005
MicroRNA-378 promotes cell survival, tumor growth, and angiogenesis by targeting SuFu and Fus-1 expression. Proc Natl Acad Sci U S A (2007) 3.92
MicroRNA MiR-17 retards tissue growth and represses fibronectin expression. Nat Cell Biol (2009) 2.49
ADAMTS-1 and ADAMTS-4 levels are elevated in thoracic aortic aneurysms and dissections. Ann Thorac Surg (2012) 2.18
Function of alternative splicing. Gene (2012) 2.00
Expression of versican 3'-untranslated region modulates endogenous microRNA functions. PLoS One (2010) 1.94
RhoGDI2 suppresses lung metastasis in mice by reducing tumor versican expression and macrophage infiltration. J Clin Invest (2012) 1.92
TGF-β modulates ovarian cancer invasion by upregulating CAF-derived versican in the tumor microenvironment. Cancer Res (2013) 1.56
Versican mediates mesenchymal-epithelial transition. Mol Biol Cell (2006) 1.34
The secreted metalloprotease ADAMTS20 is required for melanoblast survival. PLoS Genet (2008) 1.34
Versican degradation and vascular disease. Trends Cardiovasc Med (2006) 1.23
Proteolytic cleavage of versican during cardiac cushion morphogenesis. Dev Dyn (2006) 1.22
Hyperproduction of hyaluronan in neu-induced mammary tumor accelerates angiogenesis through stromal cell recruitment: possible involvement of versican/PG-M. Am J Pathol (2007) 1.22
The proteoglycan brevican binds to fibronectin after proteolytic cleavage and promotes glioma cell motility. J Biol Chem (2008) 1.16
Molecular evidence for differences in endometrium in severe versus mild endometriosis. Reprod Sci (2010) 1.16
Cartilage link protein 1 (Crtl1), an extracellular matrix component playing an important role in heart development. Dev Biol (2007) 1.15
Versican and the control of inflammation. Matrix Biol (2014) 1.13
Integrative genomic analyses of sporadic clear cell renal cell carcinoma define disease subtypes and potential new therapeutic targets. Cancer Res (2011) 1.12
The role of versican isoforms V0/V1 in glioma migration mediated by transforming growth factor-beta2. Br J Cancer (2007) 1.12
Reduced versican cleavage due to Adamts9 haploinsufficiency is associated with cardiac and aortic anomalies. Matrix Biol (2010) 1.11
Extracellular matrix and heart development. Birth Defects Res A Clin Mol Teratol (2011) 1.07
The roles of microRNAs in tumorigenesis and angiogenesis. Int J Physiol Pathophysiol Pharmacol (2010) 1.03
Versican G3 promotes mouse mammary tumor cell growth, migration, and metastasis by influencing EGF receptor signaling. PLoS One (2010) 1.03
The intermediate filament vimentin mediates microRNA miR-378 function in cellular self-renewal by regulating the expression of the Sox2 transcription factor. J Biol Chem (2012) 1.02
Versican and the regulation of cell phenotype in disease. Biochim Biophys Acta (2014) 0.99
Extracellular signal-regulated kinase activation by Neisseria gonorrhoeae downregulates epithelial cell proapoptotic proteins Bad and Bim. Infect Immun (2008) 0.99
Estradiol protects dermal hyaluronan/versican matrix during photoaging by release of epidermal growth factor from keratinocytes. J Biol Chem (2012) 0.93
Anticancer activity of Amauroderma rude. PLoS One (2013) 0.92
Versican/PG-M Assembles Hyaluronan into Extracellular Matrix and Inhibits CD44-mediated Signaling toward Premature Senescence in Embryonic Fibroblasts. J Biol Chem (2009) 0.91
A rapid increase in macrophage-derived versican and hyaluronan in infectious lung disease. Matrix Biol (2014) 0.88
Cord blood administration induces oligodendrocyte survival through alterations in gene expression. Brain Res (2010) 0.87
Arylsulfatase B (N-acetylgalactosamine-4-sulfatase): potential role as a biomarker in prostate cancer. Prostate Cancer Prostatic Dis (2013) 0.86
Versican in inflammation and tissue remodeling: the impact on lung disorders. Glycobiology (2014) 0.85
Inflammation amplification by Versican: the first mediator. Int J Mol Sci (2012) 0.85
Genetic variants A1826H and D2937Y in GAG-beta domain of versican influence susceptibility to intestinal-type gastric cancer. J Cancer Res Clin Oncol (2009) 0.84
Reprint of: A rapid increase in macrophage-derived versican and hyaluronan in infectious lung disease. Matrix Biol (2014) 0.83
Effects of increased milking frequency on gene expression in the bovine mammary gland. BMC Genomics (2008) 0.83
A role for versican in the development of leiomyosarcoma. J Biol Chem (2014) 0.83
Versican regulates metastasis of epithelial ovarian carcinoma cells and spheroids. J Ovarian Res (2014) 0.83
L-Arginine enhances cell proliferation and reduces apoptosis in human endometrial RL95-2 cells. Reprod Biol Endocrinol (2013) 0.83
Carcinoma origin dictates differential skewing of monocyte function. Oncoimmunology (2012) 0.82
Increased renal versican expression is associated with progression of chronic kidney disease. PLoS One (2012) 0.82
Cancer metastasis and EGFR signaling is suppressed by amiodarone-induced versican V2. Oncotarget (2015) 0.81
The intracellular form of human MAGP1 elicits a complex and specific transcriptional response. Int J Biochem Cell Biol (2007) 0.80
Hapln1a is required for connexin43-dependent growth and patterning in the regenerating fin skeleton. PLoS One (2014) 0.79
Effects of cleavage by a disintegrin and metalloproteinase with thrombospondin motifs-4 on gene expression and protein content of versican and aggrecan in the digital laminae of horses with starch gruel-induced laminitis. Am J Vet Res (2012) 0.79
Lumican and versican are associated with good outcome in stage II and III colon cancer. Ann Surg Oncol (2012) 0.79
Association of Versican (VCAN) gene polymorphisms rs251124 and rs2287926 (G428D), with intracranial aneurysm. Meta Gene (2014) 0.78
Human breast adipose tissue: characterization of factors that change during tumor progression in human breast cancer. J Exp Clin Cancer Res (2017) 0.77
Versican expression in canine carcinomas in benign mixed tumours: is there an association with clinical pathological factors, invasion and overall survival? BMC Vet Res (2012) 0.77
Amiodarone Induces Overexpression of Similar to Versican b to Repress the EGFR/Gsk3b/Snail Signaling Axis during Cardiac Valve Formation of Zebrafish Embryos. PLoS One (2015) 0.76
HER-2 and EGFR mRNA Expression and Its Relationship with Versican in Malignant Matrix-Producing Tumors of the Canine Mammary Gland. PLoS One (2016) 0.76
Versican V1 Overexpression Induces a Myofibroblast-Like Phenotype in Cultured Fibroblasts. PLoS One (2015) 0.76
Correlation of Versican Expression, Accumulation, and Degradation during Embryonic Development by Quantitative Immunohistochemistry. J Histochem Cytochem (2015) 0.76
Versican upregulation in Sézary cells alters growth, motility and resistance to chemotherapy. Leukemia (2015) 0.75
Versican isoforms modulate expression and function of nicotinic acetylcholine receptors. Int J Physiol Pathophysiol Pharmacol (2009) 0.75
Alteration of chondroitin sulfate composition on proteoglycan produced by knock-in mouse embryonic fibroblasts whose versican lacks the A subdomain. Ups J Med Sci (2009) 0.75
Interleukin-17A promotes tongue squamous cell carcinoma metastasis through activating miR-23b/versican pathway. Oncotarget (2016) 0.75
Characterization of Ovine Dermal Papilla Cell Aggregation. Int J Trichology (2016) 0.75
Endothelium-Independent Primitive Myxoid Vascularization Creates Invertebrate-Like Channels to Maintain Blood Supply in Optic Gliomas. Am J Pathol (2017) 0.75
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Versican V1 proteolysis in human aorta in vivo occurs at the Glu441-Ala442 bond, a site that is cleaved by recombinant ADAMTS-1 and ADAMTS-4. J Biol Chem (2001) 2.40
A novel inhibitor of cyclin-Cdk activity detected in transforming growth factor beta-arrested epithelial cells. Mol Cell Biol (1994) 2.11
Versican/PG-M G3 domain promotes tumor growth and angiogenesis. FASEB J (2004) 1.93
Transforming growth factor beta stabilizes p15INK4B protein, increases p15INK4B-cdk4 complexes, and inhibits cyclin D1-cdk4 association in human mammary epithelial cells. Mol Cell Biol (1997) 1.75
A novel regulatory mechanism in the mitogen-activated protein (MAP) kinase cascade. Role of nuclear export signal of MAP kinase kinase. J Biol Chem (1997) 1.55
Versican is selectively expressed in embryonic tissues that act as barriers to neural crest cell migration and axon outgrowth. Development (1995) 1.49
The G3 domain of versican enhances cell proliferation via epidermial growth factor-like motifs. J Biol Chem (1998) 1.39
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Regulation of stromal versican expression by breast cancer cells and importance to relapse-free survival in patients with node-negative primary breast cancer. Clin Cancer Res (2002) 1.36
beta 1-Integrin-mediated glioma cell adhesion and free radical-induced apoptosis are regulated by binding to a C-terminal domain of PG-M/versican. J Biol Chem (2002) 1.35
Elevated epidermal growth factor receptor gene copy number and expression in a squamous carcinoma cell line. J Clin Invest (1985) 1.32
cDNA cloning of PG-M, a large chondroitin sulfate proteoglycan expressed during chondrogenesis in chick limb buds. Alternative spliced multiforms of PG-M and their relationships to versican. J Biol Chem (1993) 1.27
Increased proteasome degradation of cyclin-dependent kinase inhibitor p27 is associated with a decreased overall survival in mantle cell lymphoma. Blood (2000) 1.25
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Distribution of PG-M/versican variants in human tissues and de novo expression of isoform V3 upon endothelial cell activation, migration, and neoangiogenesis in vitro. J Biol Chem (2002) 1.22
Brain derived versican V2 is a potent inhibitor of axonal growth. J Cell Sci (2000) 1.20
Versican is differentially expressed in human melanoma and may play a role in tumor development. Am J Pathol (2002) 1.20
Overexpression of the C-terminal PG-M/versican domain impairs growth of tumor cells by intervening in the interaction between epidermal growth factor receptor and beta1-integrin. J Cell Sci (2004) 1.19
Versican V1 isoform induces neuronal differentiation and promotes neurite outgrowth. Mol Biol Cell (2004) 1.17
Versican V2 is a major extracellular matrix component of the mature bovine brain. J Biol Chem (1998) 1.11
PG-M/versican binds to P-selectin glycoprotein ligand-1 and mediates leukocyte aggregation. J Cell Sci (2004) 1.08
Versican/PG-M isoforms in vascular smooth muscle cells. Arterioscler Thromb Vasc Biol (1999) 1.08
Versican enhances locomotion of astrocytoma cells and reduces cell adhesion through its G1 domain. J Neuropathol Exp Neurol (1999) 1.06
The globular domains of PG-M/versican modulate the proliferation-apoptosis equilibrium and invasive capabilities of tumor cells. FASEB J (2004) 1.01
Tandem repeats are involved in G1 domain inhibition of versican expression and secretion and the G3 domain enhances glycosaminoglycan modification and product secretion via the complement-binding protein-like motif. J Biol Chem (2000) 1.00
The G3 domain of versican inhibits mesenchymal chondrogenesis via the epidermal growth factor-like motifs. J Biol Chem (1998) 0.99
The apoptotic effect of HA14-1, a Bcl-2-interacting small molecular compound, requires Bax translocation and is enhanced by PK11195. Mol Cancer Ther (2002) 0.96
Regulation of the Ras signalling network. Bioessays (1994) 0.95
Over-expression of the chondroitin sulphate proteoglycan versican is associated with defective neural crest migration in the Pax3 mutant mouse (splotch). Mech Dev (1997) 0.94
The roles of matrix molecules in mediating chondrocyte aggregation, attachment, and spreading. J Cell Biochem (2000) 0.87
The folded modules of aggrecan G3 domain exert two separable functions in glycosaminoglycan modification and product secretion. J Biol Chem (2001) 0.85
G3 domains of aggrecan and PG-M/versican form intermolecular disulfide bonds that stabilize cell-matrix interaction. Biochemistry (2003) 0.83
Identification of the motifs and amino acids in aggrecan G1 and G2 domains involved in product secretion. Biochemistry (2003) 0.80
The Gene Ontology Annotation (GOA) Database: sharing knowledge in Uniprot with Gene Ontology. Nucleic Acids Res (2004) 18.75
An evaluation of GO annotation retrieval for BioCreAtIvE and GOA. BMC Bioinformatics (2005) 6.58
Paracrine factors of mesenchymal stem cells recruit macrophages and endothelial lineage cells and enhance wound healing. PLoS One (2008) 5.91
Distributions of microbial activities in deep subseafloor sediments. Science (2004) 4.45
MiRNA-directed regulation of VEGF and other angiogenic factors under hypoxia. PLoS One (2006) 4.29
Mammographic breast density as an intermediate phenotype for breast cancer. Lancet Oncol (2005) 3.99
MicroRNA-378 promotes cell survival, tumor growth, and angiogenesis by targeting SuFu and Fus-1 expression. Proc Natl Acad Sci U S A (2007) 3.92
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p27 phosphorylation by Src regulates inhibition of cyclin E-Cdk2. Cell (2007) 3.40
BRIT1 regulates early DNA damage response, chromosomal integrity, and cancer. Cancer Cell (2006) 2.61
MicroRNA MiR-17 retards tissue growth and represses fibronectin expression. Nat Cell Biol (2009) 2.49
MeSH Up: effective MeSH text classification for improved document retrieval. Bioinformatics (2009) 2.38
A 3'-untranslated region (3'UTR) induces organ adhesion by regulating miR-199a* functions. PLoS One (2009) 2.24
Overexpression of Akt converts radial growth melanoma to vertical growth melanoma. J Clin Invest (2007) 2.22
The interaction of versican with its binding partners. Cell Res (2005) 2.22
Expression of CD44 3'-untranslated region regulates endogenous microRNA functions in tumorigenesis and angiogenesis. Nucleic Acids Res (2010) 2.15
Expression of versican 3'-untranslated region modulates endogenous microRNA functions. PLoS One (2010) 1.94
Versican/PG-M G3 domain promotes tumor growth and angiogenesis. FASEB J (2004) 1.93
Local renin angiotensin expression regulates human mesenchymal stem cell differentiation to adipocytes. Hypertension (2006) 1.91
Assessment of disease named entity recognition on a corpus of annotated sentences. BMC Bioinformatics (2008) 1.89
MicroRNA miR-378 regulates nephronectin expression modulating osteoblast differentiation by targeting GalNT-7. PLoS One (2009) 1.88
Dual inhibition of tumor energy pathway by 2-deoxyglucose and metformin is effective against a broad spectrum of preclinical cancer models. Mol Cancer Ther (2011) 1.81
MicroRNA miR-328 regulates zonation morphogenesis by targeting CD44 expression. PLoS One (2008) 1.80
The effect of central loops in miRNA:MRE duplexes on the efficiency of miRNA-mediated gene regulation. PLoS One (2008) 1.78
The dual ErbB1/ErbB2 inhibitor, lapatinib (GW572016), cooperates with tamoxifen to inhibit both cell proliferation- and estrogen-dependent gene expression in antiestrogen-resistant breast cancer. Cancer Res (2005) 1.75
MiR-93 enhances angiogenesis and metastasis by targeting LATS2. Cell Cycle (2012) 1.74
Pharmacologic blockade of angiopoietin-2 is efficacious against model hemangiomas in mice. J Invest Dermatol (2006) 1.72
Mesenchymal stem cells use integrin beta1 not CXC chemokine receptor 4 for myocardial migration and engraftment. Mol Biol Cell (2007) 1.72
GOAnnotator: linking protein GO annotations to evidence text. J Biomed Discov Collab (2006) 1.66
Stress response of glioblastoma cells mediated by miR-17-5p targeting PTEN and the passenger strand miR-17-3p targeting MDM2. Oncotarget (2012) 1.65
MicroRNA-376c impairs transforming growth factor-β and nodal signaling to promote trophoblast cell proliferation and invasion. Hypertension (2013) 1.62
Structure and function of aggrecan. Cell Res (2002) 1.62
XB130, a novel adaptor protein for signal transduction. J Biol Chem (2007) 1.56
MicroRNA-17-5p promotes chemotherapeutic drug resistance and tumour metastasis of colorectal cancer by repressing PTEN expression. Oncotarget (2014) 1.44
Both mature miR-17-5p and passenger strand miR-17-3p target TIMP3 and induce prostate tumor growth and invasion. Nucleic Acids Res (2013) 1.44
Versican 3'-untranslated region (3'-UTR) functions as a ceRNA in inducing the development of hepatocellular carcinoma by regulating miRNA activity. FASEB J (2012) 1.44
Mature miR-17-5p and passenger miR-17-3p induce hepatocellular carcinoma by targeting PTEN, GalNT7 and vimentin in different signal pathways. J Cell Sci (2013) 1.44
The ability of versican to simultaneously cause apoptotic resistance and sensitivity. Cancer Res (2007) 1.43
MicroRNA miR-199a-3p regulates cell proliferation and survival by targeting caveolin-2. J Cell Sci (2011) 1.41
MicroRNA miR-98 inhibits tumor angiogenesis and invasion by targeting activin receptor-like kinase-4 and matrix metalloproteinase-11. Oncotarget (2012) 1.40
Notch1 regulates the growth of human colon cancers. Cancer (2010) 1.37
A retrovirus-based protein complementation assay screen reveals functional AKT1-binding partners. Proc Natl Acad Sci U S A (2006) 1.36
beta 1-Integrin-mediated glioma cell adhesion and free radical-induced apoptosis are regulated by binding to a C-terminal domain of PG-M/versican. J Biol Chem (2002) 1.35
Versican mediates mesenchymal-epithelial transition. Mol Biol Cell (2006) 1.34
The mouse excisional wound splinting model, including applications for stem cell transplantation. Nat Protoc (2013) 1.32
Analysis of allogenicity of mesenchymal stem cells in engraftment and wound healing in mice. PLoS One (2009) 1.31
Epigenetic dysregulation in mesenchymal stem cell aging and spontaneous differentiation. PLoS One (2011) 1.30
On-demand three-dimensional freeform fabrication of multi-layered hydrogel scaffold with fluidic channels. Biotechnol Bioeng (2010) 1.30
MicroRNA 376c enhances ovarian cancer cell survival by targeting activin receptor-like kinase 7: implications for chemoresistance. J Cell Sci (2011) 1.27
Phosphorylation of p27Kip1 regulates assembly and activation of cyclin D1-Cdk4. Mol Cell Biol (2008) 1.27
The role of microRNAs in self-renewal and differentiation of mesenchymal stem cells. Exp Hematol (2011) 1.25
Effects of a synthetic PEG-ylated Tie-2 agonist peptide on endotoxemic lung injury and mortality. Am J Physiol Lung Cell Mol Physiol (2011) 1.25
MicroRNA miR-24 enhances tumor invasion and metastasis by targeting PTPN9 and PTPRF to promote EGF signaling. J Cell Sci (2013) 1.25
The non-coding 3' UTR of CD44 induces metastasis by regulating extracellular matrix functions. J Cell Sci (2012) 1.24
Deregulation of p27 by oncogenic signaling and its prognostic significance in breast cancer. Breast Cancer Res (2003) 1.23
Nodal and ALK7 inhibit proliferation and induce apoptosis in human trophoblast cells. J Biol Chem (2004) 1.21
Overexpression of the C-terminal PG-M/versican domain impairs growth of tumor cells by intervening in the interaction between epidermal growth factor receptor and beta1-integrin. J Cell Sci (2004) 1.19
Micro-RNA378 (miR-378) regulates ovarian estradiol production by targeting aromatase. Endocrinology (2011) 1.19
Gene Regulation Ontology (GRO): design principles and use cases. Stud Health Technol Inform (2008) 1.18
The microRNA-302-367 cluster suppresses the proliferation of cervical carcinoma cells through the novel target AKT1. RNA (2012) 1.18
Versican V1 isoform induces neuronal differentiation and promotes neurite outgrowth. Mol Biol Cell (2004) 1.17
Nonoperative management of solitary eosinophilic granulomas of the calvaria. J Neurosurg Pediatr (2013) 1.16
High aldehyde dehydrogenase activity identifies cancer stem cells in human cervical cancer. Oncotarget (2013) 1.15
Conversion of mechanical force into biochemical signaling. J Biol Chem (2004) 1.15
A cost comparison of management of chronic hepatitis B and its associated complications in Hong Kong and Singapore. J Clin Gastroenterol (2004) 1.15
The effect of versican G3 domain on local breast cancer invasiveness and bony metastasis. Breast Cancer Res (2007) 1.14
Final results of a phase II study of nab-paclitaxel, bevacizumab, and gemcitabine as first-line therapy for patients with HER2-negative metastatic breast cancer. Breast Cancer Res Treat (2010) 1.14
The BioLexicon: a large-scale terminological resource for biomedical text mining. BMC Bioinformatics (2011) 1.13
Expression of Sox2 in human cervical carcinogenesis. Hum Pathol (2010) 1.13
Versican protects cells from oxidative stress-induced apoptosis. Matrix Biol (2005) 1.12
MiR-210 disturbs mitotic progression through regulating a group of mitosis-related genes. Nucleic Acids Res (2012) 1.11
Friend or foe: the role of microRNA in chemotherapy resistance. Acta Pharmacol Sin (2013) 1.11
Pseudolaric acid B, a novel microtubule-destabilizing agent that circumvents multidrug resistance phenotype and exhibits antitumor activity in vivo. Clin Cancer Res (2005) 1.10
Versican G3 domain regulates neurite growth and synaptic transmission of hippocampal neurons by activation of epidermal growth factor receptor. J Biol Chem (2006) 1.10
Ergosterol peroxide isolated from Ganoderma lucidum abolishes microRNA miR-378-mediated tumor cells on chemoresistance. PLoS One (2012) 1.10
Nodal induces apoptosis and inhibits proliferation in human epithelial ovarian cancer cells via activin receptor-like kinase 7. J Clin Endocrinol Metab (2004) 1.08
PG-M/versican binds to P-selectin glycoprotein ligand-1 and mediates leukocyte aggregation. J Cell Sci (2004) 1.08
WW domain binding protein-2, an E6-associated protein interacting protein, acts as a coactivator of estrogen and progesterone receptors. Mol Endocrinol (2006) 1.07
Engineering Bacillus subtilis for isobutanol production by heterologous Ehrlich pathway construction and the biosynthetic 2-ketoisovalerate precursor pathway overexpression. Appl Microbiol Biotechnol (2011) 1.07
Krüppel-like factor 4 functions as a tumor suppressor in cervical carcinoma. Cancer (2011) 1.06
Identification of novel and differentially expressed MicroRNAs of dairy goat mammary gland tissues using solexa sequencing and bioinformatics. PLoS One (2012) 1.06
Acceleration of diabetic wound healing by an angiopoietin peptide mimetic. Tissue Eng Part A (2009) 1.05
Activation of mTOR signaling pathway contributes to survival of cervical cancer cells. Gynecol Oncol (2010) 1.05
MicroRNA-378a-5p promotes trophoblast cell survival, migration and invasion by targeting Nodal. J Cell Sci (2012) 1.04
Versican G3 promotes mouse mammary tumor cell growth, migration, and metastasis by influencing EGF receptor signaling. PLoS One (2010) 1.03
An anti-let-7 sponge decoys and decays endogenous let-7 functions. Cell Cycle (2012) 1.03
The intermediate filament vimentin mediates microRNA miR-378 function in cellular self-renewal by regulating the expression of the Sox2 transcription factor. J Biol Chem (2012) 1.02
Cytoplasmic NANOG-positive stromal cells promote human cervical cancer progression. Am J Pathol (2012) 1.02
miR-29b suppresses CML cell proliferation and induces apoptosis via regulation of BCR/ABL1 protein. Exp Cell Res (2013) 1.01
The involvement of microRNAs in malignant transformation. Histol Histopathol (2012) 1.00
Identification and characterization of microRNA in the dairy goat (Capra hircus) mammary gland by Solexa deep-sequencing technology. Mol Biol Rep (2012) 1.00