Published in Biochemistry on January 18, 2005
Determinants of binding of oxidized phospholipids on apolipoprotein (a) and lipoprotein (a). J Lipid Res (2013) 1.04
Apolipoprotein(a), through its strong lysine-binding site in KIV(10'), mediates increased endothelial cell contraction and permeability via a Rho/Rho kinase/MYPT1-dependent pathway. J Biol Chem (2008) 0.91
Inhibition of plasminogen activation by apo(a): role of carboxyl-terminal lysines and identification of inhibitory domains in apo(a). J Lipid Res (2014) 0.80
Lipoprotein (a): truly a direct prothrombotic factor in cardiovascular disease? J Lipid Res (2015) 0.79
Apolipoprotein(a) inhibits in vitro tube formation in endothelial cells: identification of roles for Kringle V and the plasminogen activation system. PLoS One (2013) 0.78
Extracellular histones are major mediators of death in sepsis. Nat Med (2009) 6.55
Sensitivity of secondary structure propensities to sequence differences between alpha- and gamma-synuclein: implications for fibrillation. Protein Sci (2006) 3.73
Atherogenic lipids and lipoproteins trigger CD36-TLR2-dependent apoptosis in macrophages undergoing endoplasmic reticulum stress. Cell Metab (2010) 3.29
A polymorphism in the protease-like domain of apolipoprotein(a) is associated with severe coronary artery disease. Arterioscler Thromb Vasc Biol (2007) 2.47
Report of the National Heart, Lung, and Blood Institute Workshop on Lipoprotein(a) and Cardiovascular Disease: recent advances and future directions. Clin Chem (2003) 1.74
Prognostic value of a simple evolving disseminated intravascular coagulation score in patients with severe sepsis. Crit Care Med (2005) 1.69
Response to Shiga toxin 1 and 2 in a baboon model of hemolytic uremic syndrome. Pediatr Nephrol (2003) 1.67
A Ca(2+) switch aligns the active site of calpain. Cell (2002) 1.65
Activation of m-calpain (calpain II) by epidermal growth factor is limited by protein kinase A phosphorylation of m-calpain. Mol Cell Biol (2002) 1.64
Identification of an ITPase/XTPase in Escherichia coli by structural and biochemical analysis. Structure (2005) 1.63
Complement inhibition decreases the procoagulant response and confers organ protection in a baboon model of Escherichia coli sepsis. Blood (2010) 1.56
Oxidized phospholipids are present on plasminogen, affect fibrinolysis, and increase following acute myocardial infarction. J Am Coll Cardiol (2012) 1.55
Novel structure of the conserved gram-negative lipopolysaccharide transport protein A and mutagenesis analysis. J Mol Biol (2008) 1.47
Mechanism of bacterial cell-surface attachment revealed by the structure of cellulosomal type II cohesin-dockerin complex. Proc Natl Acad Sci U S A (2005) 1.43
Sepsis and pathophysiology of anthrax in a nonhuman primate model. Am J Pathol (2006) 1.39
Structural and biochemical evidence for an enzymatic quinone redox cycle in Escherichia coli: identification of a novel quinol monooxygenase. J Biol Chem (2004) 1.39
Tissue factor-dependent coagulation is preferentially up-regulated within arterial branching areas in a baboon model of Escherichia coli sepsis. Am J Pathol (2005) 1.37
Extracellular K+ concentration controls cell surface density of IKr in rabbit hearts and of the HERG channel in human cell lines. J Clin Invest (2009) 1.37
Sepsis-induced coagulation in the baboon lung is associated with decreased tissue factor pathway inhibitor. Am J Pathol (2007) 1.34
Crystal structure of beta-helical antifreeze protein points to a general ice binding model. Structure (2002) 1.28
Crystal structure of PhnH: an essential component of carbon-phosphorus lyase in Escherichia coli. J Bacteriol (2007) 1.22
Lipoprotein(a) as a risk factor for atherosclerosis and thrombosis: mechanistic insights from animal models. Clin Biochem (2004) 1.21
Structure of Escherichia coli tyrosine kinase Etk reveals a novel activation mechanism. EMBO J (2008) 1.20
Subclinical vitamin K deficiency in hemodialysis patients. Am J Kidney Dis (2007) 1.18
A beta-helical antifreeze protein isoform with increased activity. Structural and functional insights. J Biol Chem (2002) 1.15
Identification of an Escherichia coli O157:H7 heme oxygenase with tandem functional repeats. Proc Natl Acad Sci U S A (2005) 1.14
Lipoprotein(a) in atherosclerotic plaques recruits inflammatory cells through interaction with Mac-1 integrin. FASEB J (2006) 1.12
Lipoprotein(a): a unique risk factor for cardiovascular disease. Clin Lab Med (2006) 1.12
Synuclein-gamma targeting peptide inhibitor that enhances sensitivity of breast cancer cells to antimicrotubule drugs. Cancer Res (2007) 1.11
Lipoprotein(a): more interesting than ever after 50 years. Curr Opin Lipidol (2012) 1.06
Identification of a disulfide switch in BsSco, a member of the Sco family of cytochrome c oxidase assembly proteins. Biochemistry (2005) 1.05
Crystal structure of the alpha-kinase domain of Dictyostelium myosin heavy chain kinase A. Sci Signal (2010) 1.04
Determinants of binding of oxidized phospholipids on apolipoprotein (a) and lipoprotein (a). J Lipid Res (2013) 1.04
Structural and biochemical analysis reveal pirins to possess quercetinase activity. J Biol Chem (2005) 1.03
Infection-induced modulation of m1 and m2 phenotypes in circulating monocytes: role in immune monitoring and early prognosis of sepsis. Shock (2004) 1.03
Structure of the bifunctional isocitrate dehydrogenase kinase/phosphatase. Nature (2010) 1.00
Curiouser and curiouser: recent advances in measurement of thrombin-activatable fibrinolysis inhibitor (TAFI) and in understanding its molecular genetics, gene regulation, and biological roles. Clin Biochem (2006) 1.00
Nonnightmare distressed awakenings in veterans with posttraumatic stress disorder: response to prazosin. J Trauma Stress (2008) 1.00
Structure of PhnP, a phosphodiesterase of the carbon-phosphorus lyase pathway for phosphonate degradation. J Biol Chem (2009) 0.99
Inhibition of plasminogen activation by lipoprotein(a): critical domains in apolipoprotein(a) and mechanism of inhibition on fibrin and degraded fibrin surfaces. J Biol Chem (2003) 0.99
Autophosphorylation activates Dictyostelium myosin II heavy chain kinase A by providing a ligand for an allosteric binding site in the alpha-kinase domain. J Biol Chem (2010) 0.99
Targeting synuclein-gamma to counteract drug resistance in cancer. Expert Opin Ther Targets (2008) 0.98
Evaluation of lipoprotein(a) as a prothrombotic factor: progress from bench to bedside. Curr Opin Lipidol (2003) 0.96
Spruce budworm antifreeze protein: changes in structure and dynamics at low temperature. J Mol Biol (2003) 0.96
The complex structure of calmodulin bound to a calcineurin peptide. Proteins (2008) 0.96
Structure of the Escherichia coli O157:H7 heme oxygenase ChuS in complex with heme and enzymatic inactivation by mutation of the heme coordinating residue His-193. J Biol Chem (2006) 0.96
Effect of single nucleotide polymorphisms on expression of the gene encoding thrombin-activatable fibrinolysis inhibitor: a functional analysis. Blood (2007) 0.94
Structure of calmodulin bound to a calcineurin peptide: a new way of making an old binding mode. Biochemistry (2006) 0.94
Crystal structure of PhnZ in complex with substrate reveals a di-iron oxygenase mechanism for catabolism of organophosphonates. Proc Natl Acad Sci U S A (2014) 0.93
Emerging structural insights into bacterial tyrosine kinases. Trends Biochem Sci (2009) 0.93
X-ray crystal structure of human heme oxygenase-1 in complex with 1-(adamantan-1-yl)-2-(1H-imidazol-1-yl)ethanone: a common binding mode for imidazole-based heme oxygenase-1 inhibitors. J Med Chem (2008) 0.92
Temporal dynamics of gene expression in the lung in a baboon model of E. coli sepsis. BMC Genomics (2007) 0.92
Calpain silencing by a reversible intrinsic mechanism. Nat Struct Biol (2003) 0.92
Thrombin-thrombomodulin connects coagulation and fibrinolysis: more than an in vitro phenomenon. Blood (2007) 0.92
Scaffoldin conformation and dynamics revealed by a ternary complex from the Clostridium thermocellum cellulosome. J Biol Chem (2012) 0.91
Constitutive activation of met kinase in non-small-cell lung carcinomas correlates with anchorage-independent cell survival. J Cell Biochem (2002) 0.91
Apolipoprotein(a), through its strong lysine-binding site in KIV(10'), mediates increased endothelial cell contraction and permeability via a Rho/Rho kinase/MYPT1-dependent pathway. J Biol Chem (2008) 0.91
A novel PCR strategy for high-efficiency, automated site-directed mutagenesis. Nucleic Acids Res (2005) 0.91
Analysis of ice-binding sites in fish type II antifreeze protein by quantum mechanics. Biophys J (2002) 0.91
Chloramphenicol biosynthesis: the structure of CmlS, a flavin-dependent halogenase showing a covalent flavin-aspartate bond. J Mol Biol (2010) 0.91
Crystal structure of a novel prokaryotic Ser/Thr kinase and its implication in the Cpx stress response pathway. Mol Microbiol (2007) 0.90
A role for CCAAT/enhancer-binding protein in hepatic expression of thrombin-activable fibrinolysis inhibitor. J Biol Chem (2002) 0.90
Modulator of drug activity B from Escherichia coli: crystal structure of a prokaryotic homologue of DT-diaphorase. J Mol Biol (2006) 0.90
Contributions of F-BAR and SH2 domains of Fes protein tyrosine kinase for coupling to the FcepsilonRI pathway in mast cells. Mol Cell Biol (2008) 0.89
Structural motif-based homology modeling of CYP27A1 and site-directed mutational analyses affecting vitamin D hydroxylation. Biophys J (2006) 0.89
Determination of lipoprotein(a) kringle repeat number from genomic DNA: copy number variation genotyping using qPCR. J Lipid Res (2008) 0.89
Structure and mechanism of PhnP, a phosphodiesterase of the carbon-phosphorus lyase pathway. Biochemistry (2011) 0.89
Calpain activation by cooperative Ca2+ binding at two non-EF-hand sites. J Biol Chem (2003) 0.89
Crystal structure of a micro-like calpain reveals a partially activated conformation with low Ca2+ requirement. Structure (2003) 0.89
Insights into higher-order organization of the cellulosome revealed by a dissect-and-build approach: crystal structure of interacting Clostridium thermocellum multimodular components. J Mol Biol (2010) 0.88
Structural and biochemical characterization of gentisate 1,2-dioxygenase from Escherichia coli O157:H7. Mol Microbiol (2006) 0.88
Structure and dynamics of a beta-helical antifreeze protein. Biochemistry (2002) 0.87
A critical evaluation of the role of Lp(a) in cardiovascular disease: can Lp(a) be useful in risk assessment? Semin Vasc Med (2002) 0.87
The apolipoprotein(a) component of lipoprotein(a) stimulates actin stress fiber formation and loss of cell-cell contact in cultured endothelial cells. J Biol Chem (2003) 0.87
Catalysis of covalent Lp(a) assembly: evidence for an extracellular enzyme activity that enhances disulfide bond formation. Biochemistry (2006) 0.87
Elevated temperature and tyrosine iodination aid in the crystallization and structure determination of an antifreeze protein. Acta Crystallogr D Biol Crystallogr (2002) 0.86
Glutamate substitutions at a PKA consensus site are consistent with inactivation of calpain by phosphorylation. FEBS Lett (2003) 0.86
Computational study on the function of water within a beta-helix antifreeze protein dimer and in the process of ice-protein binding. Biophys J (2003) 0.86
Lipoprotein(a) is associated differentially with carotid stenosis, occlusion, and total plaque area. Arterioscler Thromb Vasc Biol (2008) 0.86
Purification, crystallization and preliminary X-ray analysis of isocitrate dehydrogenase kinase/phosphatase from Escherichia coli. Acta Crystallogr Sect F Struct Biol Cryst Commun (2009) 0.85
Increased production and secretion of HGF alpha-chain and an antagonistic HGF fragment in a human breast cancer progression model. Int J Cancer (2009) 0.85
Residues responsible for the asymmetric function of the nucleotide binding domains of multidrug resistance protein 1. Biochemistry (2008) 0.85
Antifreeze protein-induced morphological modification mechanisms linked to ice binding surface. J Biol Chem (2004) 0.84
Molecular mechanisms of RET receptor-mediated oncogenesis in multiple endocrine neoplasia 2B. Cancer Res (2006) 0.84
A new model for simulating 3-d crystal growth and its application to the study of antifreeze proteins. J Am Chem Soc (2003) 0.84
Structure and heme binding properties of Escherichia coli O157:H7 ChuX. Protein Sci (2009) 0.84
An identity crisis for fps/fes: oncogene or tumor suppressor? Cancer Res (2005) 0.84
Functional insights revealed by the crystal structures of Escherichia coli glucose-1-phosphatase. J Biol Chem (2003) 0.84
In vitro Activation of heme oxygenase-2 by menadione and its analogs. Med Gas Res (2014) 0.84
Quantitative evaluation of the contribution of weak lysine-binding sites present within apolipoprotein(a) kringle IV types 6-8 to lipoprotein(a) assembly. J Biol Chem (2003) 0.83
Towards a green hydrate inhibitor: imaging antifreeze proteins on clathrates. PLoS One (2010) 0.83
Structural basis of the substrate specificity of bifunctional isocitrate dehydrogenase kinase/phosphatase. Biochemistry (2011) 0.83
Activation of calpain by Ca2+: roles of the large subunit N-terminal and domain III-IV linker peptides. J Mol Biol (2004) 0.83
The role of loop 7 in mediating calcineurin regulation. Protein Eng (2003) 0.83