Published in Biochemistry on January 18, 2005
The T4 phage SF1B helicase Dda is structurally optimized to perform DNA strand separation. Structure (2012) 1.52
When a helicase is not a helicase: dsDNA tracking by the motor protein EcoR124I. EMBO J (2006) 1.51
Substrate interactions and promiscuity in a viral DNA packaging motor. Nature (2009) 1.41
DNA unwinding and protein displacement by superfamily 1 and superfamily 2 helicases. Nucleic Acids Res (2006) 1.26
Mechanisms of a ring shaped helicase. Nucleic Acids Res (2006) 1.26
Inhibition of BACH1 (FANCJ) helicase by backbone discontinuity is overcome by increased motor ATPase or length of loading strand. Nucleic Acids Res (2006) 1.15
FANCJ helicase operates in the Fanconi Anemia DNA repair pathway and the response to replicational stress. Curr Mol Med (2009) 1.00
Hepatitis C virus NS3 helicase forms oligomeric structures that exhibit optimal DNA unwinding activity in vitro. J Biol Chem (2008) 1.00
Kinetic mechanism for DNA unwinding by multiple molecules of Dda helicase aligned on DNA. Biochemistry (2010) 0.87
Mechanistic and biological aspects of helicase action on damaged DNA. Cell Cycle (2010) 0.86
Development and evaluation of a structural model for SF1B helicase Dda. Biochemistry (2009) 0.84
Close encounters for the first time: Helicase interactions with DNA damage. DNA Repair (Amst) (2015) 0.80
Regulation of the bacteriophage T4 Dda helicase by Gp32 single-stranded DNA-binding protein. DNA Repair (Amst) (2014) 0.78
Chemical modifications of DNA for study of helicase mechanisms. Bioorg Med Chem (2014) 0.75
Hepatitis C virus nonstructural protein 5A (NS5A) is an RNA-binding protein. J Biol Chem (2005) 2.61
Protein displacement by an assembly of helicase molecules aligned along single-stranded DNA. Nat Struct Mol Biol (2004) 2.29
Modulation of the hepatitis C virus RNA-dependent RNA polymerase activity by the non-structural (NS) 3 helicase and the NS4B membrane protein. J Biol Chem (2002) 1.61
Dda helicase tightly couples translocation on single-stranded DNA to unwinding of duplex DNA: Dda is an optimally active helicase. J Mol Biol (2012) 1.57
The T4 phage SF1B helicase Dda is structurally optimized to perform DNA strand separation. Structure (2012) 1.52
Purification and characterization of hepatitis C virus non-structural protein 5A expressed in Escherichia coli. Protein Expr Purif (2004) 1.45
Multiple full-length NS3 molecules are required for optimal unwinding of oligonucleotide DNA in vitro. J Biol Chem (2005) 1.30
Displacement of a DNA binding protein by Dda helicase. Nucleic Acids Res (2006) 1.30
Structural and biological identification of residues on the surface of NS3 helicase required for optimal replication of the hepatitis C virus. J Biol Chem (2005) 1.28
DNA unwinding and protein displacement by superfamily 1 and superfamily 2 helicases. Nucleic Acids Res (2006) 1.26
Pre-steady-state DNA unwinding by bacteriophage T4 Dda helicase reveals a monomeric molecular motor. Proc Natl Acad Sci U S A (2002) 1.26
Increasing the length of the single-stranded overhang enhances unwinding of duplex DNA by bacteriophage T4 Dda helicase. Biochemistry (2005) 1.21
Hepatitis C virus nonstructural protein 5A: biochemical characterization of a novel structural class of RNA-binding proteins. J Virol (2010) 1.15
Intermediates revealed in the kinetic mechanism for DNA unwinding by a monomeric helicase. Nat Struct Mol Biol (2006) 1.11
CLPM: a cross-linked peptide mapping algorithm for mass spectrometric analysis. BMC Bioinformatics (2005) 1.08
NS3 helicase from the hepatitis C virus can function as a monomer or oligomer depending on enzyme and substrate concentrations. J Biol Chem (2008) 1.04
DNA unwinding by Escherichia coli DNA helicase I (TraI) provides evidence for a processive monomeric molecular motor. J Biol Chem (2006) 1.02
Hepatitis C virus NS3 helicase forms oligomeric structures that exhibit optimal DNA unwinding activity in vitro. J Biol Chem (2008) 1.00
Investigation of translocation, DNA unwinding, and protein displacement by NS3h, the helicase domain from the hepatitis C virus helicase. Biochemistry (2010) 0.98
Yeast Pif1 helicase exhibits a one-base-pair stepping mechanism for unwinding duplex DNA. J Biol Chem (2013) 0.96
Phosphate release contributes to the rate-limiting step for unwinding by an RNA helicase. Nucleic Acids Res (2009) 0.96
RNA unwinding activity of the hepatitis C virus NS3 helicase is modulated by the NS5B polymerase. Biochemistry (2008) 0.96
Physical and functional interaction between yeast Pif1 helicase and Rim1 single-stranded DNA binding protein. Nucleic Acids Res (2012) 0.96
Non-Watson-Crick interactions between PNA and DNA inhibit the ATPase activity of bacteriophage T4 Dda helicase. Nucleic Acids Res (2002) 0.89
Superfamily 2 helicases. Front Biosci (Landmark Ed) (2012) 0.89
Targeting the single-strand G-rich overhang of telomeres with PNA inhibits cell growth and induces apoptosis of human immortal cells. Exp Cell Res (2004) 0.87
Kinetic mechanism for DNA unwinding by multiple molecules of Dda helicase aligned on DNA. Biochemistry (2010) 0.87
Development and evaluation of a structural model for SF1B helicase Dda. Biochemistry (2009) 0.84
Novel, fluorescent, SSB protein chimeras with broad utility. Protein Sci (2011) 0.83
Yeast Pif1 accelerates annealing of complementary DNA strands. Biochemistry (2014) 0.83
Analysis of the DNA translocation and unwinding activities of T4 phage helicases. Methods (2010) 0.81
Dda helicase unwinds a DNA-PNA chimeric substrate: evidence for an inchworm mechanism. Bioorg Med Chem Lett (2006) 0.81
XLPM: efficient algorithm for the analysis of protein-protein contacts using chemical cross-linking mass spectrometry. BMC Bioinformatics (2014) 0.80
AAV-2 Rep78 and HPV-16 E1 interact in vitro, modulating their ATPase activity. Biochemistry (2007) 0.78
Binding by the hepatitis C virus NS3 helicase partially melts duplex DNA. Biochemistry (2012) 0.78
A bis-alkylating triplex forming oligonucleotide inhibits intracellular reporter gene expression and prevents triplex unwinding due to helicase activity. Biochemistry (2003) 0.77
Yeast transcription co-activator Sub1 and its human homolog PC4 preferentially bind to G-quadruplex DNA. Chem Commun (Camb) (2015) 0.76
Protein displacement by helicases. Methods Mol Biol (2010) 0.76
Mechanisms: molecular machines. Curr Opin Chem Biol (2011) 0.76
Probing RNA translocases with DNA. Methods Mol Biol (2015) 0.75
A helicase staircase. Nat Struct Mol Biol (2006) 0.75