Published in Int J Cancer on May 20, 2005
Gallium compound GaQ(3) -induced Ca(2+) signalling triggers p53-dependent and -independent apoptosis in cancer cells. Br J Pharmacol (2012) 0.88
Chondroitin sulfate as a molecular portal that preferentially mediates the apoptotic killing of tumor cells by penetratin-directed mitochondria-disrupting peptides. J Biol Chem (2010) 0.85
Design and implementation of a high yield production system for recombinant expression of peptides. Microb Cell Fact (2014) 0.79
Building Cell Selectivity into CPP-Mediated Strategies. Pharmaceuticals (Basel) (2010) 0.78
Plastics and carcinogenesis: The example of vinyl chloride. J Carcinog (2012) 0.78
Engineering Salmonella as intracellular factory for effective killing of tumour cells. Sci Rep (2016) 0.75
The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment. Carcinogenesis (2009) 5.01
First-line chemotherapy with capecitabine and temozolomide in patients with metastatic pancreatic endocrine carcinomas. Cancer (2010) 2.74
The cannabinoid delta(9)-tetrahydrocannabinol inhibits RAS-MAPK and PI3K-AKT survival signalling and induces BAD-mediated apoptosis in colorectal cancer cells. Int J Cancer (2007) 2.29
Pancreatic cancer and thromboembolic disease. Lancet Oncol (2004) 2.10
Increased permeability of the blood-brain barrier to chemotherapy in metastatic brain tumors: establishing a treatment paradigm. J Clin Oncol (2007) 2.09
Pancreatic cancer screening in a prospective cohort of high-risk patients: a comprehensive strategy of imaging and genetics. Clin Cancer Res (2010) 1.92
Direct transcriptional up-regulation of cyclooxygenase-2 by hypoxia-inducible factor (HIF)-1 promotes colorectal tumor cell survival and enhances HIF-1 transcriptional activity during hypoxia. Cancer Res (2006) 1.64
Language matters: "sometimes we withdraw treatment but we never withdraw care". J Palliat Med (2007) 1.45
Nonmalignant respiratory effects of chronic arsenic exposure from drinking water among never-smokers in Bangladesh. Environ Health Perspect (2008) 1.44
Increased EP4 receptor expression in colorectal cancer progression promotes cell growth and anchorage independence. Cancer Res (2006) 1.43
Hedgehog signalling in colorectal tumour cells: induction of apoptosis with cyclopamine treatment. Int J Cancer (2004) 1.41
A prospective study of respiratory symptoms associated with chronic arsenic exposure in Bangladesh: findings from the Health Effects of Arsenic Longitudinal Study (HEALS). Thorax (2010) 1.40
Capecitabine and temozolomide (CAPTEM) for metastatic, well-differentiated neuroendocrine cancers: The Pancreas Center at Columbia University experience. Cancer Chemother Pharmacol (2013) 1.28
Autolysosomal β-catenin degradation regulates Wnt-autophagy-p62 crosstalk. EMBO J (2013) 1.26
Pancreatic proteolytic enzyme therapy compared with gemcitabine-based chemotherapy for the treatment of pancreatic cancer. J Clin Oncol (2009) 1.24
Conformational effects of a common codon 399 polymorphism on the BRCT1 domain of the XRCC1 protein. Protein J (2007) 1.22
Regression of recurrent malignant gliomas with convection-enhanced delivery of topotecan. Neurosurgery (2011) 1.14
p53 autoantibodies predict subsequent development of cancer. Int J Cancer (2005) 1.14
Multi-institutional phase II study of temozolomide administered twice daily in the treatment of recurrent high-grade gliomas. Cancer (2008) 1.13
LGR5 promotes survival in human colorectal adenoma cells and is upregulated by PGE2: implications for targeting adenoma stem cells with NSAIDs. Carcinogenesis (2013) 1.06
Preferential induction of necrosis in human breast cancer cells by a p53 peptide derived from the MDM2 binding site. Oncogene (2003) 1.06
Genomic imprinting at the WT1 gene involves a novel coding transcript (AWT1) that shows deregulation in Wilms' tumours. Hum Mol Genet (2003) 1.06
HGF/Met signalling promotes PGE(2) biogenesis via regulation of COX-2 and 15-PGDH expression in colorectal cancer cells. Carcinogenesis (2009) 1.04
Selective depletion of mutant p53 by cancer chemopreventive isothiocyanates and their structure-activity relationships. J Med Chem (2011) 1.03
Colon tumour cells increase PGE(2) by regulating COX-2 and 15-PGDH to promote survival during the microenvironmental stress of glucose deprivation. Carcinogenesis (2011) 1.02
Prostaglandin F(2alpha) stimulates motility and invasion in colorectal tumor cells. Int J Cancer (2007) 1.00
Fas-mediated apoptosis is dependent on wild-type p53 status in human cancer cells expressing a temperature-sensitive p53 mutant alanine-143. Cancer Res (2003) 1.00
Dietary intake of methionine, cysteine, and protein and urinary arsenic excretion in Bangladesh. Environ Health Perspect (2008) 0.99
Temozolomide (Temodar®) and capecitabine (Xeloda®) treatment of an aggressive corticotroph pituitary tumor. Pituitary (2011) 0.98
BAG-1 is up-regulated in colorectal tumour progression and promotes colorectal tumour cell survival through increased NF-kappaB activity. Carcinogenesis (2008) 0.96
Links between the built environment, climate and population health: interdisciplinary environmental change research in New York City. Ann Acad Med Singapore (2007) 0.96
The endogenous cannabinoid, anandamide, induces COX-2-dependent cell death in apoptosis-resistant colon cancer cells. Int J Oncol (2010) 0.94
A novel stereo-selective sulfonylurea, 1-[1-(4-aminobenzoyl)-2,3-dihydro-1H-indol-6-sulfonyl]-4-phenyl-imidazolidin-2-one, has antitumor efficacy in in vitro and in vivo tumor models. Biochem Pharmacol (2002) 0.92
A common polymorphism in XRCC1 as a biomarker of susceptibility for chemically induced genetic damage. Biomarkers (2003) 0.91
Strategy for reversing resistance to a single anticancer agent in human prostate and pancreatic carcinomas. Proc Natl Acad Sci U S A (2007) 0.91
Head and neck squamous cell carcinoma in FAMMM syndrome. Head Neck (2009) 0.91
A novel mechanism for p53 to regulate its target gene ECK in signaling apoptosis. Mol Cancer Res (2006) 0.91
Neoadjuvant chemotherapy and radiation for patients with locally unresectable pancreatic adenocarcinoma: feasibility, efficacy, and survival. J Gastrointest Surg (2007) 0.91
Apoptosis and disease: a life or death decision. EMBO Rep (2004) 0.90
Induction of apoptosis by the 16-kDa amino-terminal fragment of the insulin-like growth factor binding protein 3 in human colonic carcinoma cells. Int J Oncol (2006) 0.90
Non-hospital based registered nurses and the risk of bloodborne pathogen exposure. Ind Health (2007) 0.90
NMR solution structure of a peptide from the mdm-2 binding domain of the p53 protein that is selectively cytotoxic to cancer cells. Biochemistry (2004) 0.90
Mutational analyses of multiple oncogenic pathways in intraductal papillary mucinous neoplasms of the pancreas. Pancreas (2008) 0.89
Selective induction of apoptosis in mutant p53 premalignant and malignant cancer cells by PRIMA-1 through the c-Jun-NH2-kinase pathway. Mol Cancer Ther (2005) 0.89
Transient cerebral hypoperfusion enhances intraarterial carmustine deposition into brain tissue. J Neurooncol (2007) 0.89
The intensity and frequency of moral distress among different healthcare disciplines. J Clin Ethics (2013) 0.89
TGF-β1 signalling, connecting aberrant inflammation and colorectal tumorigenesis. Curr Pharm Des (2012) 0.88
A molecular link between E2F-1 and the MAPK cascade. J Biol Chem (2007) 0.88
Cost savings from palliative care teams and guidance for a financially viable palliative care program. Health Serv Res (2014) 0.88
The retinoblastoma protein interacts with Bag-1 in human colonic adenoma and carcinoma derived cell lines. Int J Cancer (2003) 0.87
Restoration of p53 function for selective Fas-mediated apoptosis in human and rat glioma cells in vitro and in vivo by a p53 COOH-terminal peptide. Mol Cancer Ther (2006) 0.86
PNC-28, a p53-derived peptide that is cytotoxic to cancer cells, blocks pancreatic cancer cell growth in vivo. Int J Cancer (2006) 0.85
Correlation between hydrophobic properties and efficiency of carrier-mediated membrane transduction and apoptosis of a p53 C-terminal peptide. Biochem Biophys Res Commun (2002) 0.85
Activation of targeted necrosis by a p53 peptide: a novel death pathway that circumvents apoptotic resistance. J Biol Chem (2007) 0.85
High response rates and prolonged survival in patients with corticotroph pituitary tumors and refractory Cushing disease from capecitabine and temozolomide (CAPTEM): a case series. Neurosurgery (2014) 0.84
Gene-environment interactions between DNA repair polymorphisms and exposure to the carcinogen vinyl chloride. Biomarkers (2009) 0.84
Tamoxifen paradoxically decreases paclitaxel deposition into cerebrospinal fluid of brain tumor patients. J Neurooncol (2006) 0.84
The novel antimicrotubule agent cryptophycin 52 (LY355703) induces apoptosis via multiple pathways in human prostate cancer cells. Clin Cancer Res (2002) 0.84
Intra-arterial mitoxantrone delivery in rabbits: an optical pharmacokinetic study. Neurosurgery (2011) 0.83
The role of XRCC1 polymorphisms in base excision repair of etheno-DNA adducts in French vinyl chloride workers. Int J Occup Med Environ Health (2006) 0.83
The penetratin sequence in the anticancer PNC-28 peptide causes tumor cell necrosis rather than apoptosis of human pancreatic cancer cells. Ann Surg Oncol (2008) 0.83
Protein and amino acid intakes in a rural area of Bangladesh. Food Nutr Bull (2010) 0.82
Subcellular localisation of BAG-1 and its regulation of vitamin D receptor-mediated transactivation and involucrin expression in oral keratinocytes: implications for oral carcinogenesis. Exp Cell Res (2007) 0.82
Proteomic detection of cancer in asbestosis patients using SELDI-TOF discovered serum protein biomarkers. Biomarkers (2011) 0.81
The role of alpha-helical structure in p53 peptides as a determinant for their mechanism of cell death: necrosis versus apoptosis. Adv Drug Deliv Rev (2005) 0.80
The use of fluorescent probes in the study of reactive oxygen species in pancreatic cancer cells. Methods Mol Biol (2013) 0.80
Treatment preferences of seriously ill patients. N Engl J Med (2002) 0.80
The effect of genetic polymorphisms in the vinyl chloride metabolic pathway on mutagenic risk. J Hum Genet (2007) 0.80
Redirecting apoptosis to aponecrosis induces selective cytotoxicity to pancreatic cancer cells through increased ROS, decline in ATP levels, and VDAC. Mol Cancer Ther (2013) 0.79
The feasibility of real-time in vivo optical detection of blood-brain barrier disruption with indocyanine green. J Neurooncol (2011) 0.79
Conformational effects of a common codon 751 polymorphism on the C-terminal domain of the xeroderma pigmentosum D protein. J Carcinog (2009) 0.79
The evolution of adjuvant and neoadjuvant chemotherapy and radiation for advanced pancreatic cancer: from 5-fluorouracil to GTX. Surg Oncol Clin N Am (2004) 0.79
Genetic polymorphisms of XRCC1, HOGG1 and MGMT and micronucleus occurrence in Chinese vinyl chloride-exposed workers. Carcinogenesis (2010) 0.78
Polymorphisms for vinyl chloride metabolism in French vinyl chloride workers. Int J Occup Med Environ Health (2003) 0.78
Stereotactic radiosurgery plays a critical role in enhancing long-term survival in a patient with pancreatic cancer metastatic to the brain. Anticancer Res (2013) 0.78
CYP2E1 mRNA expression, genetic polymorphisms in peripheral blood lymphocytes and liver abnormalities in Chinese VCM-exposed workers. Int J Occup Med Environ Health (2008) 0.78
Computational protein chemistry of p53 and p53 peptides. Front Biosci (2004) 0.77
Treatment of multiple endocrine neoplasia 1/2 tumors: case report and review of the literature. Oncology (2012) 0.77
A protein kinase C inhibitor induces phenotypic reversion of ras-transformed pancreatic cancer cells and cooperatively blocks tumor cell proliferation with an anti- ras peptide. Cancer Chemother Pharmacol (2002) 0.77
Significant reduction of laparotomy-associated lung metastases and subcutaneous tumors after perioperative immunomodulation with flt3 ligand in mice. Surg Innov (2005) 0.77