Published in J Biol Chem on May 18, 2010
Relationships between membrane binding, affinity and cell internalization efficacy of a cell-penetrating peptide: penetratin as a case study. PLoS One (2011) 0.85
Preparation and characterization of polysaccharide-based nanoparticles with anticoagulant activity. Int J Nanomedicine (2012) 0.82
Enhanced antitumor effects of the BRBP1 compound peptide BRBP1-TAT-KLA on human brain metastatic breast cancer. Sci Rep (2015) 0.80
TAT Modification of Alpha-Helical Anticancer Peptides to Improve Specificity and Efficacy. PLoS One (2015) 0.79
Gas-Phase Oxidation of Neutral Basic Residues in Polypeptide Cations by Periodate. J Am Soc Mass Spectrom (2016) 0.76
Bombesin analogue-mediated delivery preferentially enhances the cytotoxicity of a mitochondria-disrupting peptide in tumor cells. PLoS One (2013) 0.75
Evaluation of the use of therapeutic peptides for cancer treatment. J Biomed Sci (2017) 0.75
p53, the cellular gatekeeper for growth and division. Cell (1997) 31.04
Anti-cancer activity of targeted pro-apoptotic peptides. Nat Med (1999) 3.72
Heparanase, hyaluronan, and CD44 in cancers: a breast carcinoma perspective. Cancer Res (2006) 2.61
Targeted cancer therapy: conferring specificity to cytotoxic drugs. Acc Chem Res (2007) 2.48
Antennapedia and HIV transactivator of transcription (TAT) "protein transduction domains" promote endocytosis of high molecular weight cargo upon binding to cell surface glycosaminoglycans. J Biol Chem (2003) 2.23
Immunotoxins for targeted cancer therapy. AAPS J (2006) 1.86
Cell-penetrating peptides as delivery vehicles for biology and medicine. Org Biomol Chem (2008) 1.79
Biological characterization of two novel cathelicidin-derived peptides and identification of structural requirements for their antimicrobial and cell lytic activities. J Biol Chem (1996) 1.58
Cell-penetrating and cell-targeting peptides in drug delivery. Biochim Biophys Acta (2008) 1.54
The biological role and regulation of versican levels in cancer. Cancer Metastasis Rev (2009) 1.51
Cell-surface proteoglycans as molecular portals for cationic peptide and polymer entry into cells. Biochem Soc Trans (2007) 1.49
Thermodynamic studies and binding mechanisms of cell-penetrating peptides with lipids and glycosaminoglycans. Adv Drug Deliv Rev (2007) 1.43
Identification of an additional negative regulatory region for p53 sequence-specific DNA binding. Proc Natl Acad Sci U S A (1998) 1.39
Messenger proteins: homeoproteins, TAT and others. Curr Opin Cell Biol (2000) 1.38
Potential therapeutic application of chondroitin sulfate/dermatan sulfate. Curr Drug Discov Technol (2008) 1.33
Conformational and molecular basis for induction of apoptosis by a p53 C-terminal peptide in human cancer cells. J Biol Chem (1999) 1.27
Modulation of magainin 2-lipid bilayer interactions by peptide charge. Biochemistry (1997) 1.24
Selective inhibition of ErbB2-overexpressing breast cancer in vivo by a novel TAT-based ErbB2-targeting signal transducers and activators of transcription 3-blocking peptide. Cancer Res (2006) 1.21
On the biomedical promise of cell penetrating peptides: limits versus prospects. J Pharm Sci (2008) 1.18
Amphipathic peptide-based fusion peptides and immunoconjugates for the targeted ablation of prostate cancer cells. Cancer Res (2007) 1.16
BMAP-28, an antibiotic peptide of innate immunity, induces cell death through opening of the mitochondrial permeability transition pore. Mol Cell Biol (2002) 1.08
Novel human-derived cell-penetrating peptides for specific subcellular delivery of therapeutic biomolecules. Biochem J (2005) 1.07
Design of a tumor-homing cell-penetrating peptide. Bioconjug Chem (2007) 1.06
Preferential induction of necrosis in human breast cancer cells by a p53 peptide derived from the MDM2 binding site. Oncogene (2003) 1.06
A mitochondrial targeted fusion peptide exhibits remarkable cytotoxicity. Mol Cancer Ther (2006) 1.04
Penetratin improves tumor retention of single-chain antibodies: a novel step toward optimization of radioimmunotherapy of solid tumors. Cancer Res (2005) 1.03
Comparison of cellular uptake using 22 CPPs in 4 different cell lines. Bioconjug Chem (2008) 1.00
Peptides from the amino terminal mdm-2-binding domain of p53, designed from conformational analysis, are selectively cytotoxic to transformed cells. Proc Natl Acad Sci U S A (2001) 0.99
Novel chondroitin sulfate-binding cationic liposomes loaded with cisplatin efficiently suppress the local growth and liver metastasis of tumor cells in vivo. Cancer Res (2002) 0.97
The biological role of chondroitin sulfate in cancer and chondroitin-based anticancer agents. In Vivo (2008) 0.96
Targeted drug delivery utilizing protein-like molecular architecture. J Am Chem Soc (2007) 0.96
Direct peptide interaction with surface glycosaminoglycans contributes to the cell penetration of maurocalcine. J Biol Chem (2008) 0.95
Enhanced heparan sulfate proteoglycan-mediated uptake of cell-penetrating peptide-modified liposomes. Cell Mol Life Sci (2004) 0.94
Enhanced targeting and killing of tumor cells expressing the CXC chemokine receptor 4 by transducible anticancer peptides. Cancer Res (2005) 0.90
Platelet alpha2beta1 integrin activation: contribution of ligand internalization and the alpha2-cytoplasmic domain. Blood (2003) 0.90
Restoration of p53 function for selective Fas-mediated apoptosis in human and rat glioma cells in vitro and in vivo by a p53 COOH-terminal peptide. Mol Cancer Ther (2006) 0.86
Correlation between hydrophobic properties and efficiency of carrier-mediated membrane transduction and apoptosis of a p53 C-terminal peptide. Biochem Biophys Res Commun (2002) 0.85
PNC-28, a p53-derived peptide that is cytotoxic to cancer cells, blocks pancreatic cancer cell growth in vivo. Int J Cancer (2006) 0.85
The penetratin sequence in the anticancer PNC-28 peptide causes tumor cell necrosis rather than apoptosis of human pancreatic cancer cells. Ann Surg Oncol (2008) 0.83
Selective induction of apoptosis through the FADD/caspase-8 pathway by a p53 c-terminal peptide in human pre-malignant and malignant cells. Int J Cancer (2005) 0.83
Versican expression in human cervical cancer. Eur J Cancer (2007) 0.83
Novel peptides from the RAS-p21 and p53 proteins for the treatment of cancer. Cancer Ther (2007) 0.78
Open letter to the leader of academic medicine. BMJ (2007) 4.06
Randomized trials published in some Chinese journals: how many are randomized? Trials (2009) 2.52
Revised STandards for Reporting Interventions in Clinical Trials of Acupuncture (STRICTA): extending the CONSORT statement. Acupunct Med (2010) 2.14
Differential activation of monkey striatal neurons in the early and late stages of procedural learning. Exp Brain Res (2002) 1.97
Homocysteine impairs coronary artery endothelial function by inhibiting tetrahydrobiopterin in patients with hyperhomocysteinemia. Am J Physiol Endocrinol Metab (2010) 1.74
Procedural arrhythmia termination and long-term single-procedure clinical outcome in patients with non-paroxysmal atrial fibrillation. J Cardiovasc Electrophysiol (2013) 1.45
Emergency medical rescue efforts after a major earthquake: lessons from the 2008 Wenchuan earthquake. Lancet (2012) 1.41
Modeling and optimization of the multiobjective stochastic joint replenishment and delivery problem under supply chain environment. ScientificWorldJournal (2013) 1.38
Acetylation-mediated proteasomal degradation of core histones during DNA repair and spermatogenesis. Cell (2013) 1.35
1-(4-Isopropyl-phen-yl)-5-(4-methoxy-phen-yl)pyrazolidin-3-one. Acta Crystallogr Sect E Struct Rep Online (2008) 1.33
Cortical control of motor sequences. Curr Opin Neurobiol (2006) 1.33
GLP-2-mediated up-regulation of intestinal blood flow and glucose uptake is nitric oxide-dependent in TPN-fed piglets 1. Gastroenterology (2003) 1.31
Human peptidoglycan recognition proteins require zinc to kill both gram-positive and gram-negative bacteria and are synergistic with antibacterial peptides. J Immunol (2007) 1.15
Osteoinduction of hydroxyapatite/beta-tricalcium phosphate bioceramics in mice with a fractured fibula. Acta Biomater (2009) 1.15
Assessment of registration quality of trials sponsored by China. J Evid Based Med (2009) 1.12
The reporting quality of meta-analyses improves: a random sampling study. J Clin Epidemiol (2008) 1.12
Consolidated standards of reporting trials (CONSORT) for traditional Chinese medicine: current situation and future development. Front Med (2011) 1.11
Visualization of evidence-based medicine domain knowledge: production and citation of Cochrane systematic reviews. J Evid Based Med (2013) 1.11
An engineered multidomain bactericidal peptide as a model for targeted antibiotics against specific bacteria. Nat Biotechnol (2003) 1.11
3-Hydr-oxy-3-phenyl-isoindolin-1-one 0.33-hydrate. Acta Crystallogr Sect E Struct Rep Online (2009) 1.06
2,5-Dibromo-terephthalic acid dihydrate. Acta Crystallogr Sect E Struct Rep Online (2008) 1.06
New powerful statistics for alignment-free sequence comparison under a pattern transfer model. J Theor Biol (2011) 1.05
Searching for bidirectional promoters in Arabidopsis thaliana. BMC Bioinformatics (2009) 1.05
GhDET2, a steroid 5alpha-reductase, plays an important role in cotton fiber cell initiation and elongation. Plant J (2007) 1.05
Development of a replicon-based phenotypic assay for assessing the drug susceptibilities of HCV NS3 protease genes from clinical isolates. Antiviral Res (2008) 1.04
Neuronal activity related to reward size and rewarded target position in primate supplementary eye field. J Neurosci (2007) 1.03
Ischemic postconditioning-mediated miRNA-21 protects against cardiac ischemia/reperfusion injury via PTEN/Akt pathway. PLoS One (2013) 1.03
Constructing carbon-coated Fe₃O₄ microspheres as antiacid and magnetic support for palladium nanoparticles for catalytic applications. ACS Appl Mater Interfaces (2010) 1.03
Histidine-tryptophan-ketoglutarate solution vs. University of Wisconsin solution for liver transplantation: a systematic review. Liver Transpl (2007) 1.01
Sofosbuvir-based treatment regimens for chronic, genotype 1 hepatitis C virus infection in U.S. incarcerated populations: a cost-effectiveness analysis. Ann Intern Med (2014) 0.99
Somatotopically arranged inputs from putamen and subthalamic nucleus to primary motor cortex. Neurosci Res (2006) 0.99
Reference values of clinical chemistry and hematology parameters in rhesus monkeys (Macaca mulatta). Xenotransplantation (2009) 0.98
Involvement of inflammation-related miR-155 and miR-146a in diabetic nephropathy: implications for glomerular endothelial injury. BMC Nephrol (2014) 0.97
Adiponectin protects rat hippocampal neurons against excitotoxicity. Age (Dordr) (2010) 0.97
Association between EGF promoter polymorphisms and cancer risk: a meta-analysis. Med Oncol (2009) 0.96
Nanostructural organization and anion effects on the temperature dependence of the optical Kerr effect spectra of ionic liquids. J Phys Chem B (2007) 0.95
RseqFlow: workflows for RNA-Seq data analysis. Bioinformatics (2011) 0.95
Transmembrane TNF-α promotes suppressive activities of myeloid-derived suppressor cells via TNFR2. J Immunol (2013) 0.94
Design and evaluation of a novel evodiamine-phospholipid complex for improved oral bioavailability. AAPS PharmSciTech (2012) 0.93
Mild hypoxia-induced cardiomyocyte hypertrophy via up-regulation of HIF-1α-mediated TRPC signalling. J Cell Mol Med (2012) 0.93
Effect of hypoxia-inducible factor-1alpha silencing on the sensitivity of human brain glioma cells to doxorubicin and etoposide. Neurochem Res (2008) 0.93
Comparison of hepatic coagulant, fibrinolytic, and anticoagulant functions between Banna Minipig Inbred line and humans. Transplantation (2005) 0.93
The long-term effects of bariatric surgery for type 2 diabetes: systematic review and meta-analysis of randomized and non-randomized evidence. Obes Surg (2015) 0.93
Excretion masses and environmental occurrence of antibiotics in typical swine and dairy cattle farms in China. Sci Total Environ (2012) 0.93
IGF-I and IGFBP-3 and the risk of lung cancer: a meta-analysis based on nested case-control studies. J Exp Clin Cancer Res (2009) 0.92
The protective mechanism of ligustrazine against renal ischemia/reperfusion injury. J Surg Res (2009) 0.92
Inbred Chinese Wuzhishan (WZS) minipig model for soybean glycinin and beta-conglycinin allergy. J Agric Food Chem (2010) 0.91
Anti-tumor effects in mice induced by survivin-targeted siRNA delivered through polysaccharide nanoparticles. Biomaterials (2013) 0.91
Echinococcus multilocularis: Proteomic analysis of the protoscoleces by two-dimensional electrophoresis and mass spectrometry. Exp Parasitol (2009) 0.91
Circulating microRNAs as potential biomarkers for smoking-related interstitial fibrosis. Biomarkers (2012) 0.91
Mechanisms of cyclosporine-induced renal cell apoptosis: a systematic review. Am J Nephrol (2012) 0.90
Trends in the occurrence of human and veterinary antibiotics in the sediments of the Yellow River, Hai River and Liao River in northern China. Environ Pollut (2011) 0.90
TGFBR3, a potential negative regulator of TGF-β signaling, protects cardiac fibroblasts from hypoxia-induced apoptosis. J Cell Physiol (2011) 0.90
Accurately tuning the dispersity and size of palladium particles on carbon spheres and using carbon spheres/palladium composite as support for polyaniline in H2O2 electrochemical sensing. Langmuir (2010) 0.90
Structure activity relationships and differential interactions and functional activity of various equine estrogens mediated via estrogen receptors (ERs) ERalpha and ERbeta. Endocrinology (2008) 0.90
Mesenchymal stem cells protect islets from hypoxia/reoxygenation-induced injury. Cell Biochem Funct (2010) 0.90
2-(4-Methyl-benzo-yl)benzoic acid monohydrate. Acta Crystallogr Sect E Struct Rep Online (2008) 0.89
Rb1 postconditioning attenuates liver warm ischemia-reperfusion injury through ROS-NO-HIF pathway. Life Sci (2011) 0.89
Occurrence and fate of eleven classes of antibiotics in two typical wastewater treatment plants in South China. Sci Total Environ (2013) 0.89
Organization of multisynaptic inputs from prefrontal cortex to primary motor cortex as revealed by retrograde transneuronal transport of rabies virus. J Neurosci (2005) 0.89
PPARgamma polymorphisms and cancer risk: a meta-analysis involving 32,138 subjects. Oncol Rep (2010) 0.89
Neuroprotection of brain-derived neurotrophic factor against hypoxic injury in vitro requires activation of extracellular signal-regulated kinase and phosphatidylinositol 3-kinase. Int J Dev Neurosci (2007) 0.89
Prolonged emergency department length of stay is not associated with worse outcomes in patients with intracerebral hemorrhage. Neurocrit Care (2012) 0.89
Expression of the SET protein in testes of mice at different developmental stages. Asian J Androl (2014) 0.89
Expression, purification, and refolding of a novel immunotoxin containing humanized single-chain fragment variable antibody against CTLA4 and the N-terminal fragment of human perforin. Protein Expr Purif (2006) 0.88
The practical value of applying chemical biliary duct embolization to chemical hepatectomy for treatment of hepatolithiasis. J Surg Res (2005) 0.88
Interface pattern formation in nonlinear dissipative systems. Nat Mater (2002) 0.88
Creation of an online collection of emergency medicine literature. Acad Emerg Med (2005) 0.88
Isolation and phylogenetic characterization of bat astroviruses in southern China. Arch Virol (2011) 0.88
TRAIL-R1 polymorphisms and cancer susceptibility: an evidence-based meta-analysis. Eur J Cancer (2009) 0.87
MicroRNAs: potential biomarker in organ transplantation. Transpl Immunol (2011) 0.87
Clinicopathologic characteristics and molecular subtypes of microinvasive carcinoma of the breast. Tumour Biol (2015) 0.87
Molecular cloning, expression and characterization of the functional domain of CTLA4 from the rhesus monkey, Macaca mulatta. Dev Comp Immunol (2011) 0.87
HIF-1alpha accumulation upregulates MICA and MICB expression on human cardiomyocytes and enhances NK cell cytotoxicity during hypoxia-reoxygenation. Life Sci (2010) 0.87
Perinatal and neonatal outcomes of 494 babies delivered from 972 vitrified embryo transfers. Fertil Steril (2012) 0.87
An investigation of the conductivity of peptide nanotube networks prepared by enzyme-triggered self-assembly. Nanoscale (2010) 0.87
In vivo monitoring of angiogenesis inhibition via down-regulation of mir-21 in a VEGFR2-luc murine breast cancer model using bioluminescent imaging. PLoS One (2013) 0.87
The prevalence, antimicrobial resistance and PFGE profiles of Laribacter hongkongensis in retail freshwater fish and edible frogs of southern China. Food Microbiol (2012) 0.86
Enhancement of cytotoxicity of antimicrobial peptide magainin II in tumor cells by bombesin-targeted delivery. Acta Pharmacol Sin (2010) 0.86
The current state of knowledge, alongside recommendations for future research and practice. J Evid Based Med (2012) 0.86
Neuronal activity related to anticipated and elapsed time in macaque supplementary eye field. Exp Brain Res (2007) 0.86
MicroRNA-22 downregulation by atorvastatin in a mouse model of cardiac hypertrophy: a new mechanism for antihypertrophic intervention. Cell Physiol Biochem (2013) 0.86
Down-regulation of ALKBH2 increases cisplatin sensitivity in H1299 lung cancer cells. Acta Pharmacol Sin (2011) 0.86