Published in Virus Res on February 01, 2005
A global perspective on hantavirus ecology, epidemiology, and disease. Clin Microbiol Rev (2010) 4.64
Remote site control of an active site fidelity checkpoint in a viral RNA-dependent RNA polymerase. J Biol Chem (2005) 2.40
Discovery of an RNA virus 3'->5' exoribonuclease that is critically involved in coronavirus RNA synthesis. Proc Natl Acad Sci U S A (2006) 2.07
5-Azacytidine can induce lethal mutagenesis in human immunodeficiency virus type 1. J Virol (2009) 1.25
Mutation rates and intrinsic fidelity of retroviral reverse transcriptases. Viruses (2009) 1.19
Coronaviruses: an RNA proofreading machine regulates replication fidelity and diversity. RNA Biol (2011) 1.18
Vector-borne transmission imposes a severe bottleneck on an RNA virus population. PLoS Pathog (2012) 1.16
Ribavirin reveals a lethal threshold of allowable mutation frequency for Hantaan virus. J Virol (2007) 1.15
Insights into arbovirus evolution and adaptation from experimental studies. Viruses (2010) 1.15
The quasispecies nature and biological implications of the hepatitis C virus. Infect Genet Evol (2009) 1.14
Fitness declines in Tobacco etch virus upon serial bottleneck transfers. J Virol (2007) 1.11
Mutation of HIV-1 genomes in a clinical population treated with the mutagenic nucleoside KP1461. PLoS One (2011) 1.08
Quasispecies theory for finite populations. Phys Rev E Stat Nonlin Soft Matter Phys (2010) 1.03
Structure of foot-and-mouth disease virus mutant polymerases with reduced sensitivity to ribavirin. J Virol (2010) 1.01
Examining the theory of error catastrophe. J Virol (2006) 1.00
Characterization of a small plaque variant of West Nile virus isolated in New York in 2000. Virology (2007) 0.99
Therapeutically targeting RNA viruses via lethal mutagenesis. Future Virol (2008) 0.99
Hepatitis C virus genetic variability and evolution. World J Hepatol (2015) 0.96
Counteracting quasispecies adaptability: extinction of a ribavirin-resistant virus mutant by an alternative mutagenic treatment. PLoS One (2009) 0.94
Hepatitis C virus quasispecies in chronically infected children subjected to interferon-ribavirin therapy. Arch Virol (2010) 0.93
Back to the future: revisiting HIV-1 lethal mutagenesis. Trends Microbiol (2012) 0.90
Quasispecies theory for horizontal gene transfer and recombination. Phys Rev E Stat Nonlin Soft Matter Phys (2008) 0.89
Arboviral bottlenecks and challenges to maintaining diversity and fitness during mosquito transmission. Viruses (2014) 0.87
Drug-related mutational patterns in hepatitis B virus (HBV) reverse transcriptase proteins from Iranian treatment-naïve chronic HBV patients. Hepat Mon (2013) 0.85
Tempo and mode of inhibitor-mutagen antiviral therapies: a multidisciplinary approach. Proc Natl Acad Sci U S A (2011) 0.83
Recombination in feline lentiviral genomes during experimental cross-species infection. Virology (2006) 0.82
Analysis of intrahost variation in Venezuelan equine encephalitis virus reveals repeated deletions in the 6-kilodalton protein gene. J Virol (2011) 0.79
Lack of adaptation of chimeric GB virus B/hepatitis C virus in the marmoset model: possible effects of bottleneck. J Virol (2009) 0.79
Inferring within-patient HIV-1 evolutionary dynamics under anti-HIV therapy using serial virus samples with vSPA. BMC Bioinformatics (2009) 0.79
Multiple microRNAs targeted to internal ribosome entry site against foot-and-mouth disease virus infection in vitro and in vivo. Virol J (2014) 0.79
Analysis of Quasispecies of Avain Leukosis Virus Subgroup J Using Sanger and High-throughput Sequencing. Virol J (2016) 0.75
Dynamic Co-evolution and Interaction of Avian Leukosis Virus Genetic Variants and Host Immune Responses. Front Microbiol (2017) 0.75
Structure of foot-and-mouth disease virus RNA-dependent RNA polymerase and its complex with a template-primer RNA. J Biol Chem (2004) 2.48
A comparison of viral RNA-dependent RNA polymerases. Curr Opin Struct Biol (2005) 2.14
Suppression of viral infectivity through lethal defection. Proc Natl Acad Sci U S A (2005) 1.62
Evolutionary transition toward defective RNAs that are infectious by complementation. J Virol (2004) 1.61
Evolution of foot-and-mouth disease virus. Virus Res (2003) 1.57
The structure of a protein primer-polymerase complex in the initiation of genome replication. EMBO J (2006) 1.54
Sequential structures provide insights into the fidelity of RNA replication. Proc Natl Acad Sci U S A (2007) 1.37
Biodiversity in model ecosystems, I: coexistence conditions for competing species. J Theor Biol (2005) 1.34
Foot-and-mouth disease virus. Comp Immunol Microbiol Infect Dis (2002) 1.33
High mutation rates, bottlenecks, and robustness of RNA viral quasispecies. Gene (2005) 1.31
Resistance of virus to extinction on bottleneck passages: study of a decaying and fluctuating pattern of fitness loss. Proc Natl Acad Sci U S A (2003) 1.27
Duration and fitness dependence of quasispecies memory. J Mol Biol (2002) 1.18
Eukaryotic community distribution and its relationship to water physicochemical parameters in an extreme acidic environment, Rio Tinto (southwestern Spain). Appl Environ Microbiol (2006) 1.14
Mutant viral polymerase in the transition of virus to error catastrophe identifies a critical site for RNA binding. J Mol Biol (2005) 1.13
Analysis of ribavirin mutagenicity in human hepatitis C virus infection. J Virol (2007) 1.10
Hidden virulence determinants in a viral quasispecies in vivo. J Virol (2008) 1.06
Potential benefits of sequential inhibitor-mutagen treatments of RNA virus infections. PLoS Pathog (2009) 1.05
The dawn of the RNA World: toward functional complexity through ligation of random RNA oligomers. RNA (2009) 1.05
Topological structure of the space of phenotypes: the case of RNA neutral networks. PLoS One (2011) 1.05
Molecular basis for a lack of correlation between viral fitness and cell killing capacity. PLoS Pathog (2007) 1.04
On the structural repertoire of pools of short, random RNA sequences. J Theor Biol (2008) 1.04
Viral genome segmentation can result from a trade-off between genetic content and particle stability. PLoS Genet (2011) 1.03
Biodiversity in model ecosystems, II: species assembly and food web structure. J Theor Biol (2005) 1.03
Competition-colonization dynamics in an RNA virus. Proc Natl Acad Sci U S A (2010) 1.01
Structure of foot-and-mouth disease virus mutant polymerases with reduced sensitivity to ribavirin. J Virol (2010) 1.01
Dynamics of mutation and recombination in a replicating population of complementing, defective viral genomes. J Mol Biol (2006) 1.00
Resistance to extinction of low fitness virus subjected to plaque-to-plaque transfers: diversification by mutation clustering. J Mol Biol (2002) 0.98
Pathways to extinction: beyond the error threshold. Philos Trans R Soc Lond B Biol Sci (2010) 0.97
Collective properties of evolving molecular quasispecies. BMC Evol Biol (2007) 0.95
Beneficial effects of population bottlenecks in an RNA virus evolving at increased error rate. J Mol Biol (2008) 0.93
Phenotypic effect of mutations in evolving populations of RNA molecules. BMC Evol Biol (2010) 0.92
The impact of quasispecies dynamics on the use of therapeutics. Trends Microbiol (2012) 0.91
Fitness increase of memory genomes in a viral quasispecies. J Mol Biol (2004) 0.91
Invariant aphthovirus consensus nucleotide sequence in the transition to error catastrophe. Infect Genet Evol (2005) 0.90
Repeated bottleneck transfers can lead to non-cytocidal forms of a cytopathic virus: implications for viral extinction. J Mol Biol (2007) 0.90
Modeling viral genome fitness evolution associated with serial bottleneck events: evidence of stationary states of fitness. J Virol (2002) 0.90
Evolutionary dynamics of genome segmentation in multipartite viruses. Proc Biol Sci (2012) 0.89
A trade-off between neutrality and adaptability limits the optimization of viral quasispecies. J Theor Biol (2009) 0.89
Molecular characterization of a dual inhibitory and mutagenic activity of 5-fluorouridine triphosphate on viral RNA synthesis. Implications for lethal mutagenesis. J Mol Biol (2008) 0.89
A segmented form of foot-and-mouth disease virus interferes with standard virus: a link between interference and competitive fitness. Virology (2005) 0.88
Fitness distributions in exponentially growing asexual populations. Phys Rev Lett (2003) 0.87
Deletion mutants of VPg reveal new cytopathology determinants in a picornavirus. PLoS One (2010) 0.87
Evolutionary dynamics on networks of selectively neutral genotypes: effects of topology and sequence stability. Phys Rev E Stat Nonlin Soft Matter Phys (2009) 0.86
Influence of mutagenesis and viral load on the sustained low-level replication of an RNA virus. J Mol Biol (2011) 0.85
Identification of mutations conferring 5-azacytidine resistance in bacteriophage Qβ. Virology (2011) 0.84
Motif frequency and evolutionary search times in RNA populations. J Theor Biol (2011) 0.83
Tempo and mode of inhibitor-mutagen antiviral therapies: a multidisciplinary approach. Proc Natl Acad Sci U S A (2011) 0.83
Reconstructing evolutionary relationships from functional data: a consistent classification of organisms based on translation inhibition response. Mol Phylogenet Evol (2004) 0.81
Variable mutation rates as an adaptive strategy in replicator populations. PLoS One (2010) 0.80
New vaccine design based on defective genomes that combines features of attenuated and inactivated vaccines. PLoS One (2010) 0.79
Effects of spatial competition on the diversity of a quasispecies. Phys Rev Lett (2008) 0.79
Evolution at increased error rate leads to the coexistence of multiple adaptive pathways in an RNA virus. BMC Evol Biol (2013) 0.79
Exploration of sequence space as the basis of viral RNA genome segmentation. Proc Natl Acad Sci U S A (2014) 0.78
Struggle for space: viral extinction through competition for cells. Phys Rev Lett (2011) 0.78
Molecular dissection of a viral quasispecies under mutagenic treatment: positive correlation between fitness loss and mutational load. J Gen Virol (2012) 0.77
Severe hindrance of viral infection propagation in spatially extended hosts. PLoS One (2011) 0.75
Supercritical branching processes and the role of fluctuations under exponential population growth. J Theor Biol (2003) 0.75
Geomarkers versus biomarkers: paleoenvironmental and astrobiological significance. Ambio (2007) 0.75
Spiders: water-driven erosive structures in the southern hemisphere of Mars. Astrobiology (2006) 0.75