Published in J Virol on February 01, 2005
Inhibition of alpha/beta interferon signaling by the NS4B protein of flaviviruses. J Virol (2005) 4.31
Alpha/beta interferon protects against lethal West Nile virus infection by restricting cellular tropism and enhancing neuronal survival. J Virol (2005) 3.59
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PKR and RNase L contribute to protection against lethal West Nile Virus infection by controlling early viral spread in the periphery and replication in neurons. J Virol (2006) 3.13
Establishment and maintenance of the innate antiviral response to West Nile Virus involves both RIG-I and MDA5 signaling through IPS-1. J Virol (2007) 2.59
Resistance to alpha/beta interferon is a determinant of West Nile virus replication fitness and virulence. J Virol (2006) 2.57
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An adenosine nucleoside inhibitor of dengue virus. Proc Natl Acad Sci U S A (2009) 2.20
Blocking of interferon-induced Jak-Stat signaling by Japanese encephalitis virus NS5 through a protein tyrosine phosphatase-mediated mechanism. J Virol (2006) 2.02
The NS5 protein of the virulent West Nile virus NY99 strain is a potent antagonist of type I interferon-mediated JAK-STAT signaling. J Virol (2010) 1.94
Dysregulation of TLR3 impairs the innate immune response to West Nile virus in the elderly. J Virol (2008) 1.93
Interferon regulatory factor IRF-7 induces the antiviral alpha interferon response and protects against lethal West Nile virus infection. J Virol (2008) 1.92
RNase L plays a role in the antiviral response to West Nile virus. J Virol (2006) 1.92
West Nile virus nonstructural protein 1 inhibits TLR3 signal transduction. J Virol (2008) 1.75
High-throughput assays using a luciferase-expressing replicon, virus-like particles, and full-length virus for West Nile virus drug discovery. Antimicrob Agents Chemother (2005) 1.73
Triaryl pyrazoline compound inhibits flavivirus RNA replication. Antimicrob Agents Chemother (2006) 1.72
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West Nile virus-induced interferon production is mediated by the double-stranded RNA-dependent protein kinase PKR. J Virol (2007) 1.54
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Differential effects of mutations in NS4B on West Nile virus replication and inhibition of interferon signaling. J Virol (2007) 1.17
A single amino acid in nonstructural protein NS4B confers virulence to dengue virus in AG129 mice through enhancement of viral RNA synthesis. J Virol (2011) 1.17
Functional genomics highlights differential induction of antiviral pathways in the lungs of SARS-CoV-infected macaques. PLoS Pathog (2007) 1.16
In vitro resistance selection and in vivo efficacy of morpholino oligomers against West Nile virus. Antimicrob Agents Chemother (2007) 1.15
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Characterization of dengue virus resistance to brequinar in cell culture. Antimicrob Agents Chemother (2010) 1.13
Inhibition of dengue virus through suppression of host pyrimidine biosynthesis. J Virol (2011) 1.13
Antiviral effect of interferon lambda against West Nile virus. Antiviral Res (2009) 1.12
A single-amino acid substitution in West Nile virus 2K peptide between NS4A and NS4B confers resistance to lycorine, a flavivirus inhibitor. Virology (2008) 1.11
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Translation of the flavivirus kunjin NS3 gene in cis but not its RNA sequence or secondary structure is essential for efficient RNA packaging. J Virol (2006) 1.10
The naturally attenuated Kunjin strain of West Nile virus shows enhanced sensitivity to the host type I interferon response. J Virol (2011) 1.10
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