Published in Eur J Neurosci on January 01, 2005
In vivo fate analysis reveals the multipotent and self-renewal capacities of Sox2+ neural stem cells in the adult hippocampus. Cell Stem Cell (2007) 5.32
Adult-born hippocampal dentate granule cells undergoing maturation modulate learning and memory in the brain. J Neurosci (2009) 3.37
Murine features of neurogenesis in the human hippocampus across the lifespan from 0 to 100 years. PLoS One (2010) 2.34
Directed differentiation of hippocampal stem/progenitor cells in the adult brain. Nat Neurosci (2008) 1.89
Systemic administration of exosomes released from mesenchymal stromal cells promote functional recovery and neurovascular plasticity after stroke in rats. J Cereb Blood Flow Metab (2013) 1.85
Variability of doublecortin-associated dendrite maturation in adult hippocampal neurogenesis is independent of the regulation of precursor cell proliferation. BMC Neurosci (2006) 1.84
Fractalkine and CX 3 CR1 regulate hippocampal neurogenesis in adult and aged rats. Neurobiol Aging (2009) 1.72
Anaplastic oligodendrogliomas with 1p19q codeletion have a proneural gene expression profile. Mol Cancer (2008) 1.72
Transgenic ablation of doublecortin-expressing cells suppresses adult neurogenesis and worsens stroke outcome in mice. Proc Natl Acad Sci U S A (2010) 1.69
Prospero-related homeobox 1 gene (Prox1) is regulated by canonical Wnt signaling and has a stage-specific role in adult hippocampal neurogenesis. Proc Natl Acad Sci U S A (2011) 1.57
Krüppel-like factor 9 is necessary for late-phase neuronal maturation in the developing dentate gyrus and during adult hippocampal neurogenesis. J Neurosci (2009) 1.50
Voluntary running rescues adult hippocampal neurogenesis after irradiation of the young mouse brain. Proc Natl Acad Sci U S A (2008) 1.48
Neurogenesis and the spacing effect: learning over time enhances memory and the survival of new neurons. Learn Mem (2007) 1.48
Necessity of hippocampal neurogenesis for the therapeutic action of antidepressants in adult nonhuman primates. PLoS One (2011) 1.45
Allopregnanolone preclinical acute pharmacokinetic and pharmacodynamic studies to predict tolerability and efficacy for Alzheimer's disease. PLoS One (2015) 1.41
Gene expression profiling of neural stem cells and their neuronal progeny reveals IGF2 as a regulator of adult hippocampal neurogenesis. J Neurosci (2012) 1.40
Perinatal Choline Supplementation Reduces Amyloidosis and Increases Choline Acetyltransferase Expression in the Hippocampus of the APPswePS1dE9 Alzheimer's Disease Model Mice. PLoS One (2017) 1.39
In vivo conversion of astrocytes to neurons in the injured adult spinal cord. Nat Commun (2014) 1.38
Adult neurogenesis and neurite outgrowth are impaired in LRRK2 G2019S mice. Neurobiol Dis (2010) 1.35
Alzheimer's-type amyloidosis in transgenic mice impairs survival of newborn neurons derived from adult hippocampal neurogenesis. J Neurosci (2007) 1.34
LRRK2 knockout mice have an intact dopaminergic system but display alterations in exploratory and motor co-ordination behaviors. Mol Neurodegener (2012) 1.32
Aberrant methylation of tRNAs links cellular stress to neuro-developmental disorders. EMBO J (2014) 1.31
Environmental lead exposure during early life alters granule cell neurogenesis and morphology in the hippocampus of young adult rats. Neuroscience (2007) 1.27
Mutant alpha-synuclein exacerbates age-related decrease of neurogenesis. Neurobiol Aging (2007) 1.22
Aging-dependent changes in the radiation response of the adult rat brain. Int J Radiat Oncol Biol Phys (2007) 1.20
Neurogenesis decreases with age in the canine hippocampus and correlates with cognitive function. Neurobiol Learn Mem (2007) 1.19
Abstinence following alcohol drinking produces depression-like behavior and reduced hippocampal neurogenesis in mice. Neuropsychopharmacology (2008) 1.19
Properties of doublecortin-(DCX)-expressing cells in the piriform cortex compared to the neurogenic dentate gyrus of adult mice. PLoS One (2011) 1.17
Peripheral injection of human umbilical cord blood stimulates neurogenesis in the aged rat brain. BMC Neurosci (2008) 1.16
Ephrins as negative regulators of adult neurogenesis in diverse regions of the central nervous system. Proc Natl Acad Sci U S A (2008) 1.16
Noise trauma impairs neurogenesis in the rat hippocampus. Neuroscience (2010) 1.15
Spadin, a sortilin-derived peptide, targeting rodent TREK-1 channels: a new concept in the antidepressant drug design. PLoS Biol (2010) 1.15
Conditional ablation and recovery of forebrain neurogenesis in the mouse. J Comp Neurol (2009) 1.11
Histopathologic characterization of the BTBR mouse model of autistic-like behavior reveals selective changes in neurodevelopmental proteins and adult hippocampal neurogenesis. Mol Autism (2011) 1.11
Enigmatic central canal contacting cells: immature neurons in "standby mode"? J Neurosci (2009) 1.11
The effect of enriched environment on the outcome of traumatic brain injury; a behavioral, proteomics, and histological study. Front Neurosci (2011) 1.11
SMARCA3, a chromatin-remodeling factor, is required for p11-dependent antidepressant action. Cell (2013) 1.10
Making a neuron: Cdk5 in embryonic and adult neurogenesis. Trends Neurosci (2009) 1.08
Inflammasome-IL-1β Signaling Mediates Ethanol Inhibition of Hippocampal Neurogenesis. Front Neurosci (2012) 1.06
Mitochondrial protection attenuates inflammation-induced impairment of neurogenesis in vitro and in vivo. J Neurosci (2010) 1.06
Deletion of lysophosphatidic acid receptor LPA1 reduces neurogenesis in the mouse dentate gyrus. Mol Cell Neurosci (2008) 1.05
Enhanced neurogenesis and cell migration following focal ischemia and peripheral stimulation in mice. Dev Neurobiol (2008) 1.05
Nestin- and doublecortin-positive cells reside in adult spinal cord meninges and participate in injury-induced parenchymal reaction. Stem Cells (2011) 1.04
Release of neuronal HMGB1 by ethanol through decreased HDAC activity activates brain neuroimmune signaling. PLoS One (2014) 1.04
Treadmill exercise ameliorates short-term memory disturbance in scopolamine-induced amnesia rats. Int Neurourol J (2014) 1.03
Human in vitro reporter model of neuronal development and early differentiation processes. BMC Neurosci (2008) 1.03
Doublecortin expression in adult cat and primate cerebral cortex relates to immature neurons that develop into GABAergic subgroups. Exp Neurol (2008) 1.03
Could adult hippocampal neurogenesis be relevant for human behavior? Behav Brain Res (2011) 1.01
In vivo imaging of endogenous neural stem cells in the adult brain. World J Stem Cells (2015) 1.01
Short-term environmental enrichment enhances adult neurogenesis, vascular network and dendritic complexity in the hippocampus of type 1 diabetic mice. PLoS One (2010) 1.01
Stress experienced in utero reduces sexual dichotomies in neurogenesis, microenvironment, and cell death in the adult rat hippocampus. Dev Neurobiol (2008) 1.00
Functional recovery in rats with ischemic paraplegia after spinal grafting of human spinal stem cells. Neuroscience (2007) 1.00
Rapid anxiolytic effects of a 5-HT₄ receptor agonist are mediated by a neurogenesis-independent mechanism. Neuropsychopharmacology (2013) 0.99
Lycium barbarum polysaccharides prevent memory and neurogenesis impairments in scopolamine-treated rats. PLoS One (2014) 0.99
Permanent impairment of birth and survival of cortical and hippocampal proliferating cells following excessive drinking during alcohol dependence. Neurobiol Dis (2009) 0.99
Chronic binge-like alcohol consumption in adolescence causes depression-like symptoms possibly mediated by the effects of BDNF on neurogenesis. Neuroscience (2013) 0.99
Using an adherent cell culture of the mouse subependymal zone to study the behavior of adult neural stem cells on a single-cell level. Nat Protoc (2011) 0.99
Induction of neuronal vascular endothelial growth factor expression by cAMP in the dentate gyrus of the hippocampus is required for antidepressant-like behaviors. J Neurosci (2009) 0.99
Influence of mitochondrial enzyme deficiency on adult neurogenesis in mouse models of neurodegenerative diseases. Neuroscience (2008) 0.99
Prenatal choline supplementation attenuates neuropathological response to status epilepticus in the adult rat hippocampus. Neurobiol Dis (2008) 0.99
Cancer stem cell contribution to glioblastoma invasiveness. Stem Cell Res Ther (2013) 0.98
Chronic clozapine treatment improves prenatal infection-induced working memory deficits without influencing adult hippocampal neurogenesis. Psychopharmacology (Berl) (2009) 0.97
Suppression of adult neurogenesis increases the acute effects of kainic acid. Exp Neurol (2014) 0.97
Glycogen synthase kinase 3 inhibition promotes adult hippocampal neurogenesis in vitro and in vivo. ACS Chem Neurosci (2012) 0.96
Novel in silico Method for Teaching Cytoarchitecture, Cellular Diversity, and Gene Expression in the Mammalian Brain. J Undergrad Neurosci Educ (2007) 0.96
Chronic vagus nerve stimulation induces neuronal plasticity in the rat hippocampus. Int J Neuropsychopharmacol (2009) 0.96
Doublecortin-expressing cells persist in the associative cerebral cortex and amygdala in aged nonhuman primates. Front Neuroanat (2009) 0.95
The microtubule-associated protein doublecortin is broadly expressed in the telencephalon of adult canaries. J Chem Neuroanat (2007) 0.95
Electroconvulsive therapy induces neurogenesis in frontal rat brain areas. PLoS One (2013) 0.94
The role of VEGF/VEGFR2 signaling in peripheral stimulation-induced cerebral neurovascular regeneration after ischemic stroke in mice. Exp Brain Res (2011) 0.94
Neurogenesis in adult human brain after traumatic brain injury. J Neurotrauma (2013) 0.94
The effect of environmental harshness on neurogenesis: a large-scale comparison. Dev Neurobiol (2011) 0.93
Ecologically relevant spatial memory use modulates hippocampal neurogenesis. Proc Biol Sci (2009) 0.93
Raphe-mediated signals control the hippocampal response to SRI antidepressants via miR-16. Transl Psychiatry (2011) 0.92
Hippocampal neurogenesis and antidepressive therapy: shocking relations. Neural Plast (2014) 0.91
Potential neuronal repair in cerebral white matter injury in the human neonate. Pediatr Res (2011) 0.90
Impaired neurogenesis and neurite outgrowth in an HIV-gp120 transgenic model is reversed by exercise via BDNF production and Cdk5 regulation. J Neurovirol (2013) 0.90
"Color Timer" mice: visualization of neuronal differentiation with fluorescent proteins. Mol Brain (2010) 0.90
Birds as a model to study adult neurogenesis: bridging evolutionary, comparative and neuroethological approaches. Eur J Neurosci (2011) 0.90
Analysis of adult neurogenesis: evidence for a prominent "non-neurogenic" DCX-protein pool in rodent brain. PLoS One (2013) 0.90
Adult hippocampal neurogenesis and plasticity in the infrapyramidal bundle of the mossy fiber projection: I. Co-regulation by activity. Front Neurosci (2011) 0.89
Aggravation of chronic stress effects on hippocampal neurogenesis and spatial memory in LPA₁ receptor knockout mice. PLoS One (2011) 0.89
Age-related changes in dentate gyrus cell numbers, neurogenesis, and associations with cognitive impairments in the rhesus monkey. Front Syst Neurosci (2015) 0.89
A powerful transgenic tool for fate mapping and functional analysis of newly generated neurons. BMC Neurosci (2010) 0.88
Changes in neurogenesis in dementia and Alzheimer mouse models: are they functionally relevant? Eur Arch Psychiatry Clin Neurosci (2007) 0.88
In vivo monitoring of adult neurogenesis in health and disease. Front Neurosci (2011) 0.87
Expression of doublecortin, a neuronal migration protein, in unipolar brush cells of the vestibulocerebellum and dorsal cochlear nucleus of the adult rat. Neuroscience (2011) 0.87
Mobilization of endogenous bone marrow derived endothelial progenitor cells and therapeutic potential of parathyroid hormone after ischemic stroke in mice. PLoS One (2014) 0.87
Tis21 expression marks not only populations of neurogenic precursor cells but also new postmitotic neurons in adult hippocampal neurogenesis. Cereb Cortex (2009) 0.87
Etanercept attenuates traumatic brain injury in rats by reducing brain TNF- α contents and by stimulating newly formed neurogenesis. Mediators Inflamm (2013) 0.87
A novel site of adult doublecortin expression: neuropeptide neurons within the suprachiasmatic nucleus circadian clock. BMC Neurosci (2008) 0.86
Mobilization of neural stem cells and generation of new neurons in 6-OHDA-lesioned rats by intracerebroventricular infusion of liver growth factor. J Histochem Cytochem (2009) 0.86
Stress, glucocorticoid receptors, and adult neurogenesis: a balance between excitation and inhibition? Cell Mol Life Sci (2014) 0.86
Sublethal transient global ischemia stimulates migration of neuroblasts and neurogenesis in mice. Transl Stroke Res (2010) 0.86
IGF2 ameliorates amyloidosis, increases cholinergic marker expression and raises BMP9 and neurotrophin levels in the hippocampus of the APPswePS1dE9 Alzheimer's disease model mice. PLoS One (2014) 0.85
Absence of BRINP1 in mice causes increase of hippocampal neurogenesis and behavioral alterations relevant to human psychiatric disorders. Mol Brain (2014) 0.85
μ-Opioid receptors mediate the effects of chronic ethanol binge drinking on the hippocampal neurogenic niche. Addict Biol (2013) 0.85
Existence of a potential neurogenic system in the adult human brain. J Transl Med (2014) 0.84
Hippocampal neurogenesis is associated with migratory behaviour in adult but not juvenile sparrows (Zonotrichia leucophrys ssp.). Proc Biol Sci (2010) 0.84
Transcranial low-level laser therapy enhances learning, memory, and neuroprogenitor cells after traumatic brain injury in mice. J Biomed Opt (2014) 0.84
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med (2005) 74.55
Mechanisms underlying inflammation in neurodegeneration. Cell (2010) 7.66
Neuroplasticity: changes in grey matter induced by training. Nature (2004) 7.35
The ageing systemic milieu negatively regulates neurogenesis and cognitive function. Nature (2011) 6.71
CD133(+) and CD133(-) glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profiles. Cancer Res (2007) 6.21
Transient expression of doublecortin during adult neurogenesis. J Comp Neurol (2003) 5.61
A Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced death. Cell (2009) 4.60
Temporal and spatial dynamics of brain structure changes during extensive learning. J Neurosci (2006) 3.65
The hematopoietic factor G-CSF is a neuronal ligand that counteracts programmed cell death and drives neurogenesis. J Clin Invest (2005) 3.22
Enriched environment and physical activity stimulate hippocampal but not olfactory bulb neurogenesis. Eur J Neurosci (2003) 2.93
Temozolomide preferentially depletes cancer stem cells in glioblastoma. Cancer Res (2008) 2.84
Effects of the implementation of a telemedical stroke network: the Telemedic Pilot Project for Integrative Stroke Care (TEMPiS) in Bavaria, Germany. Lancet Neurol (2006) 2.38
Long-term survival and cell death of newly generated neurons in the adult rat olfactory bulb. Eur J Neurosci (2002) 1.96
Direct stimulation of adult neural stem cells in vitro and neurogenesis in vivo by vascular endothelial growth factor. Brain Pathol (2004) 1.89
Striatal transplantation for multiple system atrophy--are grafts affected by alpha-synucleinopathy? Exp Neurol (2009) 1.77
Transcriptional profiles of CD133+ and CD133- glioblastoma-derived cancer stem cell lines suggest different cells of origin. Cancer Res (2010) 1.76
A role for G-CSF (granulocyte-colony stimulating factor) in the central nervous system. Cell Cycle (2005) 1.59
CD133 expression and cancer stem cells predict prognosis in high-grade oligodendroglial tumors. Brain Pathol (2008) 1.56
Pluripotent stem cells in neurodegenerative and neurodevelopmental diseases. Hum Mol Genet (2010) 1.54
Increased generation of granule cells in adult Bcl-2-overexpressing mice: a role for cell death during continued hippocampal neurogenesis. Eur J Neurosci (2005) 1.53
High efficacy of clonal growth and expansion of adult neural stem cells. Lab Invest (2003) 1.47
Preoperative evaluation of carotid artery stenosis: comparison of contrast-enhanced MR angiography and duplex sonography with digital subtraction angiography. AJNR Am J Neuroradiol (2003) 1.46
Transforming growth factor-beta1 is a negative modulator of adult neurogenesis. J Neuropathol Exp Neurol (2006) 1.44
Intracranial hemorrhage: frequency, location, and risk factors identified in a TeleStroke network. Neuroreport (2015) 1.42
Inhibition of TGF-beta2 with AP 12009 in recurrent malignant gliomas: from preclinical to phase I/II studies. Oligonucleotides (2007) 1.40
Outpatient continuous inotrope infusion as an adjunct to heart failure therapy in Duchenne muscular dystrophy. Neuromuscul Disord (2006) 1.40
Gene expression profiling of neural stem cells and their neuronal progeny reveals IGF2 as a regulator of adult hippocampal neurogenesis. J Neurosci (2012) 1.40
In vivo optical imaging of neurogenesis: watching new neurons in the intact brain. Mol Imaging (2008) 1.34
Adult neural progenitor cell grafts survive after acute spinal cord injury and integrate along axonal pathways. Eur J Neurosci (2003) 1.34
Long-term effects of specialized stroke care with telemedicine support in community hospitals on behalf of the Telemedical Project for Integrative Stroke Care (TEMPiS). Stroke (2008) 1.33
LRRK2 knockout mice have an intact dopaminergic system but display alterations in exploratory and motor co-ordination behaviors. Mol Neurodegener (2012) 1.32
Alpha-synuclein alters Notch-1 expression and neurogenesis in mouse embryonic stem cells and in the hippocampus of transgenic mice. J Neurosci (2008) 1.32
The promotion of oriented axonal regrowth in the injured spinal cord by alginate-based anisotropic capillary hydrogels. Biomaterials (2006) 1.30
An autosomal recessive limb girdle muscular dystrophy (LGMD2) with mild mental retardation is allelic to Walker-Warburg syndrome (WWS) caused by a mutation in the POMT1 gene. Neuromuscul Disord (2005) 1.30
Decreased neurogenesis after cholinergic forebrain lesion in the adult rat. J Neurosci Res (2004) 1.30
Neurodegeneration and motor dysfunction in a conditional model of Parkinson's disease. J Neurosci (2008) 1.28
Lactate promotes glioma migration by TGF-beta2-dependent regulation of matrix metalloproteinase-2. Neuro Oncol (2008) 1.27
Targeted transgene expression in neuronal precursors: watching young neurons in the old brain. Eur J Neurosci (2006) 1.26
Rechallenge with temozolomide in patients with recurrent gliomas. J Neurol (2009) 1.24
Human wild-type alpha-synuclein impairs neurogenesis. J Neuropathol Exp Neurol (2004) 1.24
Cerebral ischemia-reperfusion injury in rats--a 3 T MRI study on biphasic blood-brain barrier opening and the dynamics of edema formation. J Cereb Blood Flow Metab (2009) 1.23
Striatal deafferentation increases dopaminergic neurogenesis in the adult olfactory bulb. Exp Neurol (2005) 1.22
Mutant alpha-synuclein exacerbates age-related decrease of neurogenesis. Neurobiol Aging (2007) 1.22
Pegylated liposomal doxorubicin-efficacy in patients with recurrent high-grade glioma. Cancer (2004) 1.19
Targeted tumor therapy with the TGF-beta 2 antisense compound AP 12009. Cytokine Growth Factor Rev (2005) 1.19
Dopamine receptor activation promotes adult neurogenesis in an acute Parkinson model. Exp Neurol (2009) 1.18
Adult stem cell therapy in stroke. Curr Opin Neurol (2005) 1.14
Mesenchymal stem cells instruct oligodendrogenic fate decision on adult neural stem cells. Stem Cells (2006) 1.14
Can telemedicine contribute to fulfill WHO Helsingborg Declaration of specialized stroke care? Cerebrovasc Dis (2005) 1.11
Salvage therapy in patients with glioblastoma: is there any benefit? Cancer (2003) 1.11
Lineage selection of functional and cryopreservable human embryonic stem cell-derived neurons. Stem Cells (2008) 1.10
Adult neurogenesis in Parkinson's disease. Cell Mol Life Sci (2012) 1.09
Amyloid-β contributes to blood-brain barrier leakage in transgenic human amyloid precursor protein mice and in humans with cerebral amyloid angiopathy. Stroke (2011) 1.09
Computer implementation of the international standards for neurological classification of spinal cord injury for consistent and efficient derivation of its subscores including handling of data from not testable segments. J Neurotrauma (2011) 1.09
A randomized, double blind, placebo-controlled trial of pioglitazone in combination with riluzole in amyotrophic lateral sclerosis. PLoS One (2012) 1.09
SoxC transcription factors are required for neuronal differentiation in adult hippocampal neurogenesis. J Neurosci (2012) 1.08
The dark side of BrdU in neural stem cell biology: detrimental effects on cell cycle, differentiation and survival. Cell Tissue Res (2011) 1.08
Long-term course and mutational spectrum of spatacsin-linked spastic paraplegia. Ann Neurol (2007) 1.08
Letter by Schlachetzki et al regarding article, "endovascular stroke therapy: tirofiban is associated with risk of fatal intracerebral hemorrhage and poor outcome". Stroke (2013) 1.07
TGF-beta in neural stem cells and in tumors of the central nervous system. Cell Tissue Res (2007) 1.06
Impaired adult neurogenesis in mice lacking the transcription factor E2F1. Mol Cell Neurosci (2002) 1.04
Purification of Schwann cells by selection of p75 low affinity nerve growth factor receptor expressing cells from adult peripheral nerve. J Neurosci Methods (2003) 1.04
Accumulation of oligomer-prone α-synuclein exacerbates synaptic and neuronal degeneration in vivo. Brain (2014) 1.03
Human in vitro reporter model of neuronal development and early differentiation processes. BMC Neurosci (2008) 1.03