Published in Am J Hum Genet on January 18, 2005
Identification of Genes Predisposing to Atherosclerosis | NCT00059098
Handling marker-marker linkage disequilibrium: pedigree analysis with clustered markers. Am J Hum Genet (2005) 6.12
Joint modeling of linkage and association: identifying SNPs responsible for a linkage signal. Am J Hum Genet (2005) 3.62
Overview of techniques to account for confounding due to population stratification and cryptic relatedness in genomic data association analyses. Heredity (Edinb) (2010) 1.11
Exploring causality via identification of SNPs or haplotypes responsible for a linkage signal. Genet Epidemiol (2007) 1.10
High-resolution association mapping of quantitative trait loci: a population-based approach. Genetics (2005) 1.05
On the statistical properties of family-based association tests in datasets containing both pedigrees and unrelated case-control samples. Eur J Hum Genet (2011) 0.89
Improvement of mapping accuracy by unifying linkage and association analysis. Genetics (2005) 0.82
A gene frequency model for QTL mapping using Bayesian inference. Genet Sel Evol (2010) 0.82
A narrow and highly significant linkage signal for severe bipolar disorder in the chromosome 5q33 region in Latin American pedigrees. Am J Med Genet B Neuropsychiatr Genet (2009) 0.79
Combined linkage disequilibrium and linkage mapping: Bayesian multilocus approach. Heredity (Edinb) (2013) 0.77
Bayesian quantitative trait locus mapping based on reconstruction of recent genetic histories. Genetics (2009) 0.76
A logistic mixture model for a family-based association study. BMC Proc (2007) 0.75
Statistical genetic approaches for mapping ophthalmic trait and disease genes. Am J Ophthalmol (2009) 0.75
Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM). Am J Hum Genet (1993) 51.42
A general model for the genetic analysis of pedigree data. Hum Hered (1971) 40.17
Construction of multilocus genetic linkage maps in humans. Proc Natl Acad Sci U S A (1987) 35.83
Estimation of the recombination fraction in human pedigrees: efficient computation of the likelihood for human linkage studies. Am J Hum Genet (1974) 23.66
Combined linkage and association sib-pair analysis for quantitative traits. Am J Hum Genet (1999) 11.22
The family based association test method: strategies for studying general genotype--phenotype associations. Eur J Hum Genet (2001) 9.09
A haplotype-based 'haplotype relative risk' approach to detecting allelic associations. Hum Hered (1992) 8.71
An extended transmission/disequilibrium test (TDT) for multi-allele marker loci. Ann Hum Genet (1995) 5.47
Faster multipoint linkage analysis using Fourier transforms. J Comput Biol (1998) 3.87
Familial combined hyperlipidemia is associated with upstream transcription factor 1 (USF1). Nat Genet (2004) 2.86
Linkage analysis in the presence of errors IV: joint pseudomarker analysis of linkage and/or linkage disequilibrium on a mixture of pedigrees and singletons when the mode of inheritance cannot be accurately specified. Am J Hum Genet (2000) 2.85
Linkage analysis in the presence of errors III: marker loci and their map as nuisance parameters. Am J Hum Genet (2000) 2.35
A comparative study of sibship tests of linkage and/or association. Am J Hum Genet (1998) 2.15
Accounting for linkage in family-based tests of association with missing parental genotypes. Am J Hum Genet (2003) 1.92
Genetic susceptibility to multiple sclerosis linked to myelin basic protein gene. Lancet (1992) 1.79
Exploring positional candidate genes: linkage conditional on measured genotype. Behav Genet (2004) 1.56
Linkage of familial combined hyperlipidaemia to chromosome 1q21-q23. Nat Genet (1998) 1.52
Combined analysis of genetic segregation and linkage under an oligogenic model. Comput Biomed Res (1984) 1.41
Gamete-competition models. Am J Hum Genet (2000) 1.28
Mapping of complex traits by single-nucleotide polymorphisms. Am J Hum Genet (1998) 1.05
Combined linkage and linkage disequilibrium mapping for genome screens. Genet Epidemiol (2000) 0.98
Pedigree linkage disequilibrium mapping of quantitative trait loci. Eur J Hum Genet (2005) 0.95
SNPs and snails and puppy dogs' tails: analysis of SNP haplotype data using the gamete competition model. Ann Hum Genet (2001) 0.93
Combined linkage and association tests in mx. Behav Genet (2004) 0.89
Combined high resolution linkage and association mapping of quantitative trait loci. Eur J Hum Genet (2003) 0.88
Fast model-based estimation of ancestry in unrelated individuals. Genome Res (2009) 15.63
Genome-wide association analysis by lasso penalized logistic regression. Bioinformatics (2009) 12.21
Prioritizing GWAS results: A review of statistical methods and recommendations for their application. Am J Hum Genet (2010) 5.39
Detection and integration of genotyping errors in statistical genetics. Am J Hum Genet (2002) 4.89
Genome-wide association studies identify four ER negative-specific breast cancer risk loci. Nat Genet (2013) 3.81
Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease: consensus statement of the European Atherosclerosis Society. Eur Heart J (2013) 3.58
A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor-negative breast cancer. Nat Genet (2011) 3.37
The landscape of recombination in African Americans. Nature (2011) 3.06
Genome-wide association study of prostate cancer in men of African ancestry identifies a susceptibility locus at 17q21. Nat Genet (2011) 2.70
Meta-analysis identifies common variants associated with body mass index in east Asians. Nat Genet (2012) 2.70
Association screening of common and rare genetic variants by penalized regression. Bioinformatics (2010) 2.67
Mutations in LMF1 cause combined lipase deficiency and severe hypertriglyceridemia. Nat Genet (2007) 2.60
A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11. Hum Mol Genet (2012) 2.45
A treasure trove for lipoprotein biology. Nat Genet (2008) 2.25
A systems genetics approach implicates USF1, FADS3, and other causal candidate genes for familial combined hyperlipidemia. PLoS Genet (2009) 2.24
Penalized estimation of haplotype frequencies. Bioinformatics (2008) 2.19
Enhancements to the ADMIXTURE algorithm for individual ancestry estimation. BMC Bioinformatics (2011) 2.16
Enhanced statistical tests for GWAS in admixed populations: assessment using African Americans from CARe and a Breast Cancer Consortium. PLoS Genet (2011) 1.94
A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry. Nat Genet (2013) 1.82
Association of stearoyl-CoA desaturase 1 activity with familial combined hyperlipidemia. Arterioscler Thromb Vasc Biol (2008) 1.81
A quasi-Newton acceleration for high-dimensional optimization algorithms. Stat Comput (2011) 1.80
Hyperglycemia and a common variant of GCKR are associated with the levels of eight amino acids in 9,369 Finnish men. Diabetes (2012) 1.78
Common variants at 11q12, 10q26 and 3p11.2 are associated with prostate cancer susceptibility in Japanese. Nat Genet (2012) 1.59
Genetic causes of high and low serum HDL-cholesterol. J Lipid Res (2010) 1.55
Characterizing genetic risk at known prostate cancer susceptibility loci in African Americans. PLoS Genet (2011) 1.54
Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry. PLoS Genet (2011) 1.47
Familial combined hyperlipidemia in Mexicans: association with upstream transcription factor 1 and linkage on chromosome 16q24.1. Arterioscler Thromb Vasc Biol (2005) 1.46
Fine-mapping of breast cancer susceptibility loci characterizes genetic risk in African Americans. Hum Mol Genet (2011) 1.45
Genome scans provide evidence for low-HDL-C loci on chromosomes 8q23, 16q24.1-24.2, and 20q13.11 in Finnish families. Am J Hum Genet (2002) 1.45
Fine mapping of regulatory loci for mammalian gene expression using radiation hybrids. Nat Genet (2008) 1.41
MM Algorithms for Some Discrete Multivariate Distributions. J Comput Graph Stat (2010) 1.36
Genomic study in Mexicans identifies a new locus for triglycerides and refines European lipid loci. J Med Genet (2013) 1.26
Cross-species analyses implicate Lipin 1 involvement in human glucose metabolism. Hum Mol Genet (2005) 1.25
Linkage analysis without defined pedigrees. Genet Epidemiol (2011) 1.20
Strong correlation between meiotic crossovers and haplotype structure in a 2.5-Mb region on the long arm of chromosome 21. Genome Res (2005) 1.20
Stability selection for genome-wide association. Genet Epidemiol (2011) 1.18
Genotype imputation via matrix completion. Genome Res (2012) 1.18
USF1 and dyslipidemias: converging evidence for a functional intronic variant. Hum Mol Genet (2005) 1.16
Common hepatic nuclear factor-4alpha variants are associated with high serum lipid levels and the metabolic syndrome. Diabetes (2006) 1.15
The SLC6A14 gene shows evidence of association with obesity. J Clin Invest (2003) 1.15
Risk alleles of USF1 gene predict cardiovascular disease of women in two prospective studies. PLoS Genet (2006) 1.13
The N342S MYLIP polymorphism is associated with high total cholesterol and increased LDL receptor degradation in humans. J Clin Invest (2011) 1.12
Analysis of Latino populations from GALA and MEC studies reveals genomic loci with biased local ancestry estimation. Bioinformatics (2013) 1.11
Admixture mapping identifies a locus on 6q25 associated with breast cancer risk in US Latinas. Hum Mol Genet (2012) 1.11
A genome-wide association study of breast cancer in women of African ancestry. Hum Genet (2012) 1.11
Graphics Processing Units and High-Dimensional Optimization. Stat Sci (2010) 1.10
Genetic variation in Native Americans, inferred from Latino SNP and resequencing data. Mol Biol Evol (2011) 1.08
Evaluating genetic risk for prostate cancer among Japanese and Latinos. Cancer Epidemiol Biomarkers Prev (2012) 1.08
Association of the APOLIPOPROTEIN A1/C3/A4/A5 gene cluster with triglyceride levels and LDL particle size in familial combined hyperlipidemia. Circ Res (2004) 1.07
WW-domain-containing oxidoreductase is associated with low plasma HDL-C levels. Am J Hum Genet (2008) 1.06
Investigation of variants identified in caucasian genome-wide association studies for plasma high-density lipoprotein cholesterol and triglycerides levels in Mexican dyslipidemic study samples. Circ Cardiovasc Genet (2009) 1.01
USF1 contributes to high serum lipid levels in Dutch FCHL families and U.S. whites with coronary artery disease. Arterioscler Thromb Vasc Biol (2007) 1.01
RECONSTRUCTING DNA COPY NUMBER BY PENALIZED ESTIMATION AND IMPUTATION. Ann Appl Stat (2010) 1.01
A Path Algorithm for Constrained Estimation. J Comput Graph Stat (2013) 0.97
Copy number alterations in prostate tumors and disease aggressiveness. Genes Chromosomes Cancer (2011) 0.97
Reproducibility, performance, and clinical utility of a genetic risk prediction model for prostate cancer in Japanese. PLoS One (2012) 0.96
Intelligence in Williams Syndrome is related to STX1A, which encodes a component of the presynaptic SNARE complex. PLoS One (2010) 0.96
A Poisson model for random multigraphs. Bioinformatics (2010) 0.94
Codon and rate variation models in molecular phylogeny. Mol Biol Evol (2002) 0.94
Familial combined hyperlipidemia: upstream transcription factor 1 and beyond. Curr Opin Lipidol (2006) 0.94
Modeling maternal-offspring gene-gene interactions: the extended-MFG test. Genet Epidemiol (2010) 0.93
Vocabulon: a dictionary model approach for reconstruction and localization of transcription factor binding sites. Bioinformatics (2004) 0.93
Association of ketone body levels with hyperglycemia and type 2 diabetes in 9,398 Finnish men. Diabetes (2013) 0.92
Powerful allele sharing statistics for nonparametric linkage analysis. Hum Hered (2004) 0.91
Upstream transcription factor 1 influences plasma lipid and metabolic traits in mice. Hum Mol Genet (2009) 0.91
Locus for elevated apolipoprotein B levels on chromosome 1p31 in families with familial combined hyperlipidemia. Circ Res (2002) 0.90
Adipose co-expression networks across Finns and Mexicans identify novel triglyceride-associated genes. BMC Med Genomics (2012) 0.90
Identification of two common variants contributing to serum apolipoprotein B levels in Mexicans. Arterioscler Thromb Vasc Biol (2009) 0.90
A nonsynonymous SNP within PCDH15 is associated with lipid traits in familial combined hyperlipidemia. Hum Genet (2009) 0.89
Quantitative trait Loci association mapping by imputation of strain origins in multifounder crosses. Genetics (2011) 0.89
Merging microsatellite data. J Comput Biol (2006) 0.88
Galanin preproprotein is associated with elevated plasma triglycerides. Arterioscler Thromb Vasc Biol (2008) 0.88
A novel nonsense apolipoprotein A-I mutation (apoA-I(E136X)) causes low HDL cholesterol in French Canadians. Atherosclerosis (2005) 0.88
Reconstructing ancestral haplotypes with a dictionary model. J Comput Biol (2006) 0.87
Unraveling the complex genetics of familial combined hyperlipidemia. Ann Med (2006) 0.87
Evidence for a gene influencing high-density lipoprotein cholesterol on chromosome 4q31.21. Arterioscler Thromb Vasc Biol (2005) 0.87
Genetic variation at the proprotein convertase subtilisin/kexin type 5 gene modulates high-density lipoprotein cholesterol levels. Circ Cardiovasc Genet (2009) 0.87
A heterozygote-homozygote test of Hardy-Weinberg equilibrium. Eur J Hum Genet (2009) 0.87
A genome-wide scan for breast cancer risk haplotypes among African American women. PLoS One (2013) 0.87
A candidate gene study in low HDL-cholesterol families provides evidence for the involvement of the APOA2 gene and the APOA1C3A4 gene cluster. Atherosclerosis (2002) 0.86
A dictionary model for haplotyping, genotype calling, and association testing. Genet Epidemiol (2007) 0.86
Mendel-GPU: haplotyping and genotype imputation on graphics processing units. Bioinformatics (2012) 0.86
Expression of the placental transcriptome in maternal nutrient reduction in baboons is dependent on fetal sex. J Nutr (2013) 0.85
Effects of genome-wide copy number variation on expression in mammalian cells. BMC Genomics (2011) 0.85
Mixed effects models for quantitative trait loci mapping with inbred strains. Genetics (2008) 0.84
Locus for quantitative HDL-cholesterol on chromosome 10q in Finnish families with dyslipidemia. J Lipid Res (2004) 0.84
A powerful score test to detect positive selection in genome-wide scans. Eur J Hum Genet (2010) 0.84
Directed mammalian gene regulatory networks using expression and comparative genomic hybridization microarray data from radiation hybrids. PLoS Comput Biol (2009) 0.84
Bayesian Gaussian Mixture Models for High-Density Genotyping Arrays. J Am Stat Assoc (2008) 0.84
Evidence of how rs7575840 influences apolipoprotein B-containing lipid particles. Arterioscler Thromb Vasc Biol (2011) 0.84
Reconstructing DNA copy number by joint segmentation of multiple sequences. BMC Bioinformatics (2012) 0.84
Fine mapping and association studies of a high-density lipoprotein cholesterol linkage region on chromosome 16 in French-Canadian subjects. Eur J Hum Genet (2009) 0.83
Accommodating chromosome inversions in linkage analysis. Am J Hum Genet (2006) 0.83
Exome sequencing identifies 2 rare variants for low high-density lipoprotein cholesterol in an extended family. Circ Cardiovasc Genet (2012) 0.82
Estimating ethnic admixture from pedigree data. Am J Hum Genet (2008) 0.82
Transgenic expression and genetic variation of Lmf1 affect LPL activity in mice and humans. Arterioscler Thromb Vasc Biol (2012) 0.81
Population genetic structure and origins of Native Hawaiians in the multiethnic cohort study. PLoS One (2012) 0.79