PubRank

Patrizia Hrelia

Author PubWeight™ 59.46‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Intra- and inter-laboratory variation in the scoring of micronuclei and nucleoplasmic bridges in binucleated human lymphocytes. Results of an international slide-scoring exercise by the HUMN project. Mutat Res 2003 3.49
2 Growth inhibition, cell-cycle arrest and apoptosis in human T-cell leukemia by the isothiocyanate sulforaphane. Carcinogenesis 2002 1.22
3 Sulforaphane as a promising molecule for fighting cancer. Mutat Res 2006 1.12
4 Antitumor activity of sustained N-myc reduction in rhabdomyosarcomas and transcriptional block by antigene therapy. Clin Cancer Res 2011 1.05
5 Modulation of phase II enzymes by sulforaphane: implications for its cardioprotective potential. J Agric Food Chem 2009 1.03
6 Sulforaphane as a potential protective phytochemical against neurodegenerative diseases. Oxid Med Cell Longev 2013 1.03
7 Association between imatinib transporters and metabolizing enzymes genotype and response in newly diagnosed chronic myeloid leukemia patients receiving imatinib therapy. Haematologica 2012 1.00
8 Micronuclei frequencies in hospital workers occupationally exposed to low levels of ionizing radiation: influence of smoking status and other factors. Mutagenesis 2002 0.98
9 Natural isothiocyanates: genotoxic potential versus chemoprevention. Mutat Res 2011 0.95
10 Micronuclei in humans induced by exposure to low level of ionizing radiation: influence of polymorphisms in DNA repair genes. Mutat Res 2005 0.94
11 Sulforaphane increases the efficacy of doxorubicin in mouse fibroblasts characterized by p53 mutations. Mutat Res 2006 0.93
12 Micronucleus frequency in human peripheral blood lymphocytes as a biomarker for the early detection of colorectal cancer risk. Mutagenesis 2014 0.93
13 Sulforaphane protects cortical neurons against 5-S-cysteinyl-dopamine-induced toxicity through the activation of ERK1/2, Nrf-2 and the upregulation of detoxification enzymes. Mol Nutr Food Res 2010 0.92
14 Polymorphisms in OCTN1 and OCTN2 transporters genes are associated with prolonged time to progression in unresectable gastrointestinal stromal tumours treated with imatinib therapy. Pharmacol Res 2012 0.91
15 Protective effects of cyanidin-3-O-beta-glucopyranoside against UVA-induced oxidative stress in human keratinocytes. Photochem Photobiol 2005 0.91
16 Plasma antioxidant enzymes and clastogenic factors as possible biomarkers of colorectal cancer risk. Mutat Res 2011 0.91
17 Sulforaphane as a promising molecule for fighting cancer. Cancer Treat Res 2014 0.91
18 Spectrum of chromosomal aberrations in peripheral lymphocytes of hospital workers occupationally exposed to low doses of ionizing radiation. Mutat Res 2004 0.88
19 Rational approach to discover multipotent anti-Alzheimer drugs. J Med Chem 2005 0.88
20 Exposure to low environmental levels of benzene: evaluation of micronucleus frequencies and S-phenylmercapturic acid excretion in relation to polymorphisms in genes encoding metabolic enzymes. Mutat Res 2010 0.87
21 Neuroprotective effect of sulforaphane in 6-hydroxydopamine-lesioned mouse model of Parkinson's disease. Neurotoxicology 2013 0.86
22 Neuroprotective effects of cyanidin 3-O-glucopyranoside on amyloid beta (25-35) oligomer-induced toxicity. Neurosci Lett 2010 0.86
23 Clinical relevance of pharmacogenetics in gastrointestinal stromal tumor treatment in the era of personalized therapy. Pharmacogenomics 2013 0.86
24 Inherited susceptibility to bleomycin-induced micronuclei: correlating polymorphisms in GSTT1, GSTM1 and DNA repair genes with mutagen sensitivity. Mutat Res 2007 0.86
25 Effects of environmental benzene: micronucleus frequencies and haematological values in traffic police working in an urban area. Mutat Res 2005 0.85
26 Apoptosis and modulation of cell cycle control by bile acids in human leukemia T cells. Ann N Y Acad Sci 2009 0.84
27 Novel class of quinone-bearing polyamines as multi-target-directed ligands to combat Alzheimer's disease. J Med Chem 2007 0.84
28 Isothiocyanates as novel cytotoxic and cytostatic agents: molecular pathway on human transformed and non-transformed cells. Biochem Pharmacol 2004 0.84
29 Neuroprotective effects of anthocyanins and their in vivo metabolites in SH-SY5Y cells. Neurosci Lett 2007 0.83
30 Micronuclei frequency induced by bleomycin in human peripheral lymphocytes: correlating BLHX polymorphism with mutagen sensitivity. Mutat Res 2007 0.83
31 Induction of apoptosis in two human leukemia cell lines as well as differentiation in human promyelocytic cells by cyanidin-3-O-beta-glucopyranoside. Biochem Pharmacol 2004 0.83
32 Inhibition by beta-caryophyllene of ethyl methanesulfonate-induced clastogenicity in cultured human lymphocytes. Mutat Res 2010 0.83
33 Sulforaphane as an inducer of glutathione prevents oxidative stress-induced cell death in a dopaminergic-like neuroblastoma cell line. J Neurochem 2009 0.83
34 Multitargeted drugs discovery: balancing anti-amyloid and anticholinesterase capacity in a single chemical entity. Bioorg Med Chem Lett 2010 0.82
35 Sulforaphane modulates cell cycle and apoptosis in transformed and non-transformed human T lymphocytes. Ann N Y Acad Sci 2003 0.82
36 Protective effect of creatine against RNA damage. Mutat Res 2009 0.82
37 The new isothiocyanate 4-(methylthio)butylisothiocyanate selectively affects cell-cycle progression and apoptosis induction of human leukemia cells. Invest New Drugs 2004 0.82
38 Multitarget-directed drug design strategy: a novel molecule designed to block epidermal growth factor receptor (EGFR) and to exert proapoptotic effects. J Med Chem 2006 0.82
39 RNA as a new target for toxic and protective agents. Mutat Res 2008 0.81
40 Polyamine conjugation of curcumin analogues toward the discovery of mitochondria-directed neuroprotective agents. J Med Chem 2010 0.81
41 Combination of doxorubicin and sulforaphane for reversing doxorubicin-resistant phenotype in mouse fibroblasts with p53Ser220 mutation. Ann N Y Acad Sci 2007 0.81
42 Micronucleus formation and induction of apoptosis by different isothiocyanates and a mixture of isothiocyanates in human lymphocyte cultures. Mutat Res 2005 0.81
43 Effect of sulforaphane on micronucleus induction in cultured human lymphocytes by four different mutagens. Environ Mol Mutagen 2005 0.80
44 Design, synthesis, and biological evaluation of prazosin-related derivatives as multipotent compounds. J Med Chem 2005 0.80
45 Mitochondrial pathway mediates the antileukemic effects of Hemidesmus indicus, a promising botanical drug. PLoS One 2011 0.80
46 Cell-cycle specificity of sulforaphane-mediated apoptosis in Jurkat T-leukemia cells. In Vivo 2007 0.80
47 Apoptosis induction by sulfur-containing compounds in malignant and nonmalignant human cells. Environ Mol Mutagen 2009 0.80
48 Environmental exposure to benzene, micronucleus formation and polymorphisms in DNA-repair genes: a pilot study. Mutat Res 2012 0.79
49 Cyanidin 3-O-glucopyranoside protects and rescues SH-SY5Y cells against amyloid-beta peptide-induced toxicity. Neuroreport 2008 0.79
50 Genotoxicity of lavender oil, linalyl acetate, and linalool on human lymphocytes in vitro. Environ Mol Mutagen 2011 0.78
51 Neuroprotective effects of erucin against 6-hydroxydopamine-induced oxidative damage in a dopaminergic-like neuroblastoma cell line. Int J Mol Sci 2012 0.78
52 Relevance of apple consumption for protection against oxidative damage induced by hydrogen peroxide in human lymphocytes. Br J Nutr 2007 0.78
53 Biomarkers to assess the genetic damage induced by alcohol abuse in human lymphocytes. Mutat Res 2002 0.78
54 Induction of differentiation in human promyelocytic cells by the isothiocyanate sulforaphane. In Vivo 2008 0.78
55 In vitro antitumor activity of cyanidin-3-O-beta-glucopyranoside. Chemotherapy 2005 0.78
56 Cytotoxic effect of potato aspartic proteases (StAPs) on Jurkat T cells. Fitoterapia 2009 0.78
57 Red chicory (Cichorium intybus L. cultivar) as a potential source of antioxidant anthocyanins for intestinal health. Oxid Med Cell Longev 2013 0.78
58 Sulforaphane potentiates RNA damage induced by different xenobiotics. PLoS One 2012 0.77
59 Metabolic and toxicological considerations of botanicals in anticancer therapy. Expert Opin Drug Metab Toxicol 2012 0.77
60 Effect of cyanidin 3-O-beta-glucopyranoside on micronucleus induction in cultured human lymphocytes by four different mutagens. Environ Mol Mutagen 2004 0.77
61 Exploiting the lipoic acid structure in the search for novel multitarget ligands against Alzheimer's disease. Eur J Med Chem 2011 0.77
62 2-Arylbenzofuran-based molecules as multipotent Alzheimer's disease modifying agents. Eur J Med Chem 2012 0.77
63 Exploiting RNA as a new biomolecular target for synthetic polyamines. Gene 2013 0.77
64 In vitro anticancer activity of cyanidin-3-O-beta-glucopyranoside: effects on transformed and non-transformed T lymphocytes. Anticancer Res 2005 0.76
65 Generation and characterization of bioluminescent xenograft mouse models of MLL-related acute leukemias and in vivo evaluation of luciferase-targeting siRNA nanoparticles. Int J Oncol 2012 0.76
66 Cold-storage affects antioxidant properties of apples in Caco-2 cells. J Nutr 2004 0.76
67 Investigation of the photochemical properties and in vitro phototoxic potential of bumetanide. Photochem Photobiol Sci 2003 0.76
68 Design, synthesis and biological evaluation of new naphtalene diimides bearing isothiocyanate functionality. Eur J Med Chem 2011 0.76
69 Lack of correlation between environmental or biological indicators of benzene exposure at parts per billion levels and micronuclei induction. Environ Res 2003 0.75
70 Diet and risk of cancer. Lancet 2003 0.75
71 Novel polyamine analogues: from substrates towards potential inhibitors of monoamine oxidases. Eur J Med Chem 2013 0.75
72 Genotoxicity assessment of β-caryophyllene oxide. Regul Toxicol Pharmacol 2013 0.75
73 Anticlastogenic effect in human lymphocytes by the sodium salt of 3,4-secoisopimar-4(18),7,15-trien-3-oic acid. J Nat Prod 2012 0.75
74 In vitro cytotoxicity and genotoxicity of chlorinated drinking waters sampled along the distribution system of two municipal networks. Mutat Res 2007 0.75
75 A mutated p53 status did not prevent the induction of apoptosis by sulforaphane, a promising anti-cancer drug. Invest New Drugs 2005 0.75
76 Use of the Comet test and micronucleus assay on human white blood cells for in vitro assessment of genotoxicity induced by different drinking water disinfection protocols. Environ Mol Mutagen 2005 0.75
77 Polymorphisms in DNA repair genes: link with biomarkers of the CBMN cytome assay in hospital workers chronically exposed to low doses of ionising radiation. Arh Hig Rada Toksikol 2015 0.75
78 Design, synthesis, and biological evaluation of substituted 2,3-dihydro-1H-cyclopenta[b]quinolin-9-ylamine related compounds as fructose-1,6-bisphosphatase inhibitors. Bioorg Med Chem 2006 0.75