Published in J Immunol on February 01, 2005
The chlamydial plasmid-encoded protein pgp3 is secreted into the cytosol of Chlamydia-infected cells. Infect Immun (2008) 1.97
Characterization of fifty putative inclusion membrane proteins encoded in the Chlamydia trachomatis genome. Infect Immun (2008) 1.77
Killing me softly: chlamydial use of proteolysis for evading host defenses. Trends Microbiol (2009) 1.47
The hypothetical protein CT813 is localized in the Chlamydia trachomatis inclusion membrane and is immunogenic in women urogenitally infected with C. trachomatis. Infect Immun (2006) 1.47
A MyD88-dependent early IL-17 production protects mice against airway infection with the obligate intracellular pathogen Chlamydia muridarum. J Immunol (2009) 1.39
Intracellular interleukin-1alpha mediates interleukin-8 production induced by Chlamydia trachomatis infection via a mechanism independent of type I interleukin-1 receptor. Infect Immun (2007) 1.37
Inhibition of proteolytic activity of a chlamydial proteasome/protease-like activity factor by antibodies from humans infected with Chlamydia trachomatis. Infect Immun (2005) 1.21
Chlamydia trachomatis secretion of proteases for manipulating host signaling pathways. Front Microbiol (2011) 1.14
Antibodies from women urogenitally infected with C. trachomatis predominantly recognized the plasmid protein pgp3 in a conformation-dependent manner. BMC Microbiol (2008) 1.10
Secretion of the chlamydial virulence factor CPAF requires the Sec-dependent pathway. Microbiology (2010) 1.08
Chlamydia trachomatis secretion of hypothetical protein CT622 into host cell cytoplasm via a secretion pathway that can be inhibited by the type III secretion system inhibitor compound 1. Microbiology (2011) 1.07
Characterization of hypothetical proteins Cpn0146, 0147, 0284 & 0285 that are predicted to be in the Chlamydia pneumoniae inclusion membrane. BMC Microbiol (2007) 1.03
Host-Cell Survival and Death During Chlamydia Infection. Curr Immunol Rev (2007) 0.93
Induction of protective immunity against Chlamydia muridarum intravaginal infection with a chlamydial glycogen phosphorylase. PLoS One (2012) 0.91
Leishmania infection inhibits cycloheximide-induced macrophage apoptosis in a strain-dependent manner. Exp Parasitol (2009) 0.89
Meningococcal porin PorB prevents cellular apoptosis in a toll-like receptor 2- and NF-kappaB-independent manner. Infect Immun (2009) 0.83
Artery buckling stimulates cell proliferation and NF-κB signaling. Am J Physiol Heart Circ Physiol (2014) 0.83
The apicomplexan pathogen Neospora caninum inhibits host cell apoptosis in the absence of discernible NF-kappa B activation. Infect Immun (2007) 0.82
The Chlamydia pneumoniae Inclusion Membrane Protein Cpn1027 Interacts with Host Cell Wnt Signaling Pathway Regulator Cytoplasmic Activation/Proliferation-Associated Protein 2 (Caprin2). PLoS One (2015) 0.81
Buckling Reduces eNOS Production and Stimulates Extracellular Matrix Remodeling in Arteries in Organ Culture. Ann Biomed Eng (2016) 0.75
Prevalence of diabetes among men and women in China. N Engl J Med (2010) 19.98
Genomic transcriptional profiling of the developmental cycle of Chlamydia trachomatis. Proc Natl Acad Sci U S A (2003) 4.00
Effects of metformin versus glipizide on cardiovascular outcomes in patients with type 2 diabetes and coronary artery disease. Diabetes Care (2012) 2.84
Prevention of Chlamydia-induced infertility by inhibition of local caspase activity. J Infect Dis (2013) 2.79
Genome-wide identification of Chlamydia trachomatis antigens associated with trachomatous trichiasis. Invest Ophthalmol Vis Sci (2012) 2.13
In vivo whole animal body imaging reveals colonization of Chlamydia muridarum to the lower genital tract at early stages of infection. Mol Imaging Biol (2014) 2.03
Activation of Raf/MEK/ERK/cPLA2 signaling pathway is essential for chlamydial acquisition of host glycerophospholipids. J Biol Chem (2003) 1.97
The chlamydial plasmid-encoded protein pgp3 is secreted into the cytosol of Chlamydia-infected cells. Infect Immun (2008) 1.97
Caspase-1 contributes to Chlamydia trachomatis-induced upper urogenital tract inflammatory pathologies without affecting the course of infection. Infect Immun (2007) 1.85
Characterization of fifty putative inclusion membrane proteins encoded in the Chlamydia trachomatis genome. Infect Immun (2008) 1.77
A live-attenuated chlamydial vaccine protects against trachoma in nonhuman primates. J Exp Med (2011) 1.70
Profiling of human antibody responses to Chlamydia trachomatis urogenital tract infection using microplates arrayed with 156 chlamydial fusion proteins. Infect Immun (2006) 1.67
Cleavage of host keratin 8 by a Chlamydia-secreted protease. Infect Immun (2004) 1.64
Intranasal vaccination with a secreted chlamydial protein enhances resolution of genital Chlamydia muridarum infection, protects against oviduct pathology, and is highly dependent upon endogenous gamma interferon production. Infect Immun (2006) 1.63
The secreted protease factor CPAF is responsible for degrading pro-apoptotic BH3-only proteins in Chlamydia trachomatis-infected cells. J Biol Chem (2006) 1.60
Chlamydia-infected cells continue to undergo mitosis and resist induction of apoptosis. Infect Immun (2004) 1.60
Prevalence of hypertension in china: a cross-sectional study. PLoS One (2013) 1.60
Human antibody responses to a Chlamydia-secreted protease factor. Infect Immun (2004) 1.59
Coactivators and corepressors of NF-kappaB in IkappaB alpha gene promoter. J Biol Chem (2005) 1.57
A genome-wide profiling of the humoral immune response to Chlamydia trachomatis infection reveals vaccine candidate antigens expressed in humans. J Immunol (2010) 1.55
Mice deficient in MyD88 Develop a Th2-dominant response and severe pathology in the upper genital tract following Chlamydia muridarum infection. J Immunol (2010) 1.49
Degradation of the proapoptotic proteins Bik, Puma, and Bim with Bcl-2 domain 3 homology in Chlamydia trachomatis-infected cells. Infect Immun (2005) 1.48
Tumor necrosis factor alpha production from CD8+ T cells mediates oviduct pathological sequelae following primary genital Chlamydia muridarum infection. Infect Immun (2011) 1.48
The hypothetical protein CT813 is localized in the Chlamydia trachomatis inclusion membrane and is immunogenic in women urogenitally infected with C. trachomatis. Infect Immun (2006) 1.47
CT694 and pgp3 as serological tools for monitoring trachoma programs. PLoS Negl Trop Dis (2012) 1.40
A MyD88-dependent early IL-17 production protects mice against airway infection with the obligate intracellular pathogen Chlamydia muridarum. J Immunol (2009) 1.39
Intracellular interleukin-1alpha mediates interleukin-8 production induced by Chlamydia trachomatis infection via a mechanism independent of type I interleukin-1 receptor. Infect Immun (2007) 1.37
Cleavage-dependent activation of a chlamydia-secreted protease. Mol Microbiol (2004) 1.37
Impact of waist circumference and body mass index on risk of cardiometabolic disorder and cardiovascular disease in Chinese adults: a national diabetes and metabolic disorders survey. PLoS One (2013) 1.37
Chlamydia trachomatis infection inhibits both Bax and Bak activation induced by staurosporine. Infect Immun (2004) 1.36
Structural basis for activation and inhibition of the secreted chlamydia protease CPAF. Cell Host Microbe (2008) 1.36
Antigen-specific CD4+ T cells produce sufficient IFN-gamma to mediate robust protective immunity against genital Chlamydia muridarum infection. J Immunol (2008) 1.34
Chlamydia trachomatis pulmonary infection induces greater inflammatory pathology in immunoglobulin A deficient mice. Cell Immunol (2004) 1.34
Chlamydia vaccine candidates and tools for chlamydial antigen discovery. Expert Rev Vaccines (2009) 1.34
Characterization of Chlamydia trachomatis plasmid-encoded open reading frames. J Bacteriol (2013) 1.31
Adipocyte fatty acid-binding protein modulates inflammatory responses in macrophages through a positive feedback loop involving c-Jun NH2-terminal kinases and activator protein-1. J Biol Chem (2010) 1.28
Intranasal immunization with chlamydial protease-like activity factor and CpG deoxynucleotides enhances protective immunity against genital Chlamydia muridarum infection. Vaccine (2007) 1.28
Chlamydial protease-like activity factor induces protective immunity against genital chlamydial infection in transgenic mice that express the human HLA-DR4 allele. Infect Immun (2006) 1.27
Production of a proteolytically active protein, chlamydial protease/proteasome-like activity factor, by five different Chlamydia species. Infect Immun (2005) 1.26
Intramolecular dimerization is required for the chlamydia-secreted protease CPAF to degrade host transcriptional factors. Infect Immun (2004) 1.25
Inhibition of host cell cytokinesis by Chlamydia trachomatis infection. J Infect (2003) 1.24
Serum lipids and lipoproteins in Chinese men and women. Circulation (2012) 1.21
Genome-wide identification of Chlamydia trachomatis antigens associated with tubal factor infertility. Fertil Steril (2011) 1.21
Inhibition of proteolytic activity of a chlamydial proteasome/protease-like activity factor by antibodies from humans infected with Chlamydia trachomatis. Infect Immun (2005) 1.21
The biphasic role of NF-kappaB in progression and chemoresistance of ovarian cancer. Clin Cancer Res (2011) 1.19
Multi-genome identification and characterization of chlamydiae-specific type III secretion substrates: the Inc proteins. BMC Genomics (2011) 1.18
Characterization of Pgp3, a Chlamydia trachomatis plasmid-encoded immunodominant antigen. J Bacteriol (2010) 1.18
The protective efficacy of chlamydial protease-like activity factor vaccination is dependent upon CD4+ T cells. Cell Immunol (2006) 1.16
Immunogenicity and protective efficacy against murine tuberculosis of a prime-boost regimen with BCG and a DNA vaccine expressing ESAT-6 and Ag85A fusion protein. Clin Dev Immunol (2011) 1.11
Medical care and payment for diabetes in China: enormous threat and great opportunity. PLoS One (2012) 1.10
Chlamydia trachomatis antigens recognized in women with tubal factor infertility, normal fertility, and acute infection. Obstet Gynecol (2012) 1.10
Antibodies from women urogenitally infected with C. trachomatis predominantly recognized the plasmid protein pgp3 in a conformation-dependent manner. BMC Microbiol (2008) 1.10
Reduced live organism recovery and lack of hydrosalpinx in mice infected with plasmid-free Chlamydia muridarum. Infect Immun (2013) 1.10
Association of tubal factor infertility with elevated antibodies to Chlamydia trachomatis caseinolytic protease P. Am J Obstet Gynecol (2010) 1.09
Overcoming acquired resistance to TRAIL by chemotherapeutic agents and calpain inhibitor I through distinct mechanisms. Mol Ther (2004) 1.08
Secretion of the chlamydial virulence factor CPAF requires the Sec-dependent pathway. Microbiology (2010) 1.08
Chlamydia trachomatis secretion of hypothetical protein CT622 into host cell cytoplasm via a secretion pathway that can be inhibited by the type III secretion system inhibitor compound 1. Microbiology (2011) 1.07
Chronic administration of BMS309403 improves endothelial function in apolipoprotein E-deficient mice and in cultured human endothelial cells. Br J Pharmacol (2011) 1.07
Up-regulation of adiponectin by resveratrol: the essential roles of the Akt/FOXO1 and AMP-activated protein kinase signaling pathways and DsbA-L. J Biol Chem (2010) 1.06
Chlamydia pneumoniae secretion of a protease-like activity factor for degrading host cell transcription factors required for [correction of factors is required for] major histocompatibility complex antigen expression. Infect Immun (2002) 1.06
Oviduct infection and hydrosalpinx in DBA1/j mice is induced by intracervical but not intravaginal inoculation with Chlamydia muridarum. PLoS One (2013) 1.06
Metalloprotease inhibitors GM6001 and TAPI-0 inhibit the obligate intracellular human pathogen Chlamydia trachomatis by targeting peptide deformylase of the bacterium. J Biol Chem (2006) 1.06
A limited role for antibody in protective immunity induced by rCPAF and CpG vaccination against primary genital Chlamydia muridarum challenge. FEMS Immunol Med Microbiol (2009) 1.05
Generation and characterization of a large panel of murine monoclonal antibodies against vaccinia virus. Virology (2010) 1.05
Identification of Chlamydia trachomatis outer membrane complex proteins by differential proteomics. J Bacteriol (2010) 1.05
OxLDL stimulates cell proliferation through a general induction of cell cycle proteins. Am J Physiol Heart Circ Physiol (2003) 1.05
Enhanced protection against tuberculosis by vaccination with recombinant BCG over-expressing HspX protein. Vaccine (2010) 1.05
Inhibition of staurosporine-induced activation of the proapoptotic multidomain Bcl-2 proteins Bax and Bak by three invasive chlamydial species. J Infect (2006) 1.05
Loss of Jak2 impairs endothelial function by attenuating Raf-1/MEK1/Sp-1 signaling along with altered eNOS activities. Am J Pathol (2013) 1.04
The chlamydial periplasmic stress response serine protease cHtrA is secreted into host cell cytosol. BMC Microbiol (2011) 1.04
Induction of cross-serovar protection against genital chlamydial infection by a targeted multisubunit vaccination approach. Clin Vaccine Immunol (2007) 1.04
Enantioselective Diels-Alder reaction of simple alpha,beta-unsaturated ketones with a cinchona alkaloid catalyst. J Am Chem Soc (2008) 1.03
Characterization of hypothetical proteins Cpn0146, 0147, 0284 & 0285 that are predicted to be in the Chlamydia pneumoniae inclusion membrane. BMC Microbiol (2007) 1.03
Infection of myocytes with chlamydiae. Microbiology (2002) 1.01
A regulator from Chlamydia trachomatis modulates the activity of RNA polymerase through direct interaction with the beta subunit and the primary sigma subunit. Genes Dev (2009) 1.01
Transformation of Chlamydia muridarum reveals a role for Pgp5 in suppression of plasmid-dependent gene expression. J Bacteriol (2013) 1.00
Autoprocessing and self-activation of the secreted protease CPAF in Chlamydia-infected cells. Microb Pathog (2010) 1.00
Lixisenatide treatment improves glycaemic control in Asian patients with type 2 diabetes mellitus inadequately controlled on metformin with or without sulfonylurea: a randomized, double-blind, placebo-controlled, 24-week trial (GetGoal-M-Asia). Diabetes Metab Res Rev (2014) 0.99
Distinct changes in serum fibroblast growth factor 21 levels in different subtypes of diabetes. J Clin Endocrinol Metab (2011) 0.98