Published in Circ Res on January 20, 2005
Autonomic-immune-vascular interaction: an emerging concept for neurogenic hypertension. Hypertension (2011) 1.48
Characterization of a functional (pro)renin receptor in rat brain neurons. Exp Physiol (2008) 1.16
Area-specific differences in transmitter release in central catecholaminergic neurons of spontaneously hypertensive rats. Hypertension (2008) 0.90
Redox-sensitive oxidation and phosphorylation of PTEN contribute to enhanced activation of PI3K/Akt signaling in rostral ventrolateral medulla and neurogenic hypertension in spontaneously hypertensive rats. Antioxid Redox Signal (2012) 0.88
Chronic blockade of phosphatidylinositol 3-kinase in the nucleus tractus solitarii is prohypertensive in the spontaneously hypertensive rat. Hypertension (2008) 0.87
Angiotensin-converting enzyme inhibition, but not AT(1) receptor blockade, in the solitary tract nucleus improves baroreflex sensitivity in anesthetized transgenic hypertensive (mRen2)27 rats. Hypertens Res (2011) 0.87
Brain injury after intracerebral hemorrhage in spontaneously hypertensive rats. J Neurosurg (2011) 0.84
Chronic knockdown of the nucleus of the solitary tract AT1 receptors increases blood inflammatory-endothelial progenitor cell ratio and exacerbates hypertension in the spontaneously hypertensive rat. Hypertension (2013) 0.84
Differential modulation of brainstem phosphatidylinositol 3-kinase/Akt and extracellular signal-regulated kinase 1/2 signaling underlies WIN55,212-2 centrally mediated pressor response in conscious rats. J Pharmacol Exp Ther (2011) 0.84
Shift to an involvement of phosphatidylinositol 3-kinase in angiotensin II actions on nucleus tractus solitarii neurons of the spontaneously hypertensive rat. Circ Res (2009) 0.83
In vivo expression of angiotensin-(1-7) lowers blood pressure and improves baroreflex function in transgenic (mRen2)27 rats. J Cardiovasc Pharmacol (2012) 0.82
The use of viral gene transfer in studies of brainstem noradrenergic and serotonergic neurons. Philos Trans R Soc Lond B Biol Sci (2009) 0.79
Role of phosphoinositide 3-kinase in the pathogenesis of acute pancreatitis. World J Gastroenterol (2014) 0.78
Impaired CBF regulation and high CBF threshold contribute to the increased sensitivity of spontaneously hypertensive rats to cerebral ischemia. Neuroscience (2014) 0.76
Disruption of intraflagellar transport in adult mice leads to obesity and slow-onset cystic kidney disease. Curr Biol (2007) 3.76
SNO-hemoglobin is not essential for red blood cell-dependent hypoxic vasodilation. Nat Med (2008) 3.02
Hypertension and prolonged vasoconstrictor signaling in RGS2-deficient mice. J Clin Invest (2003) 2.68
Evidence for angiotensin-converting enzyme 2 as a therapeutic target for the prevention of pulmonary hypertension. Am J Respir Crit Care Med (2009) 2.40
Circulating angiotensin II and dietary salt: converging signals for neurogenic hypertension. Curr Hypertens Rep (2007) 2.23
Prevention of angiotensin II-induced cardiac remodeling by angiotensin-(1-7). Am J Physiol Heart Circ Physiol (2006) 2.17
Real-time imaging of de novo arteriovenous malformation in a mouse model of hereditary hemorrhagic telangiectasia. J Clin Invest (2009) 2.13
Cerebroprotection by angiotensin-(1-7) in endothelin-1-induced ischaemic stroke. Exp Physiol (2011) 1.99
Brain microglial cytokines in neurogenic hypertension. Hypertension (2010) 1.97
Brain renin-angiotensin system dysfunction in hypertension: recent advances and perspectives. Br J Pharmacol (2003) 1.93
Protection from angiotensin II-induced cardiac hypertrophy and fibrosis by systemic lentiviral delivery of ACE2 in rats. Exp Physiol (2005) 1.85
Heightened epithelial Na+ channel-mediated Na+ absorption in a murine polycystic kidney disease model epithelium lacking apical monocilia. Am J Physiol Cell Physiol (2005) 1.74
Genetic ablation of the BMPR2 gene in pulmonary endothelium is sufficient to predispose to pulmonary arterial hypertension. Circulation (2008) 1.72
Diminazene attenuates pulmonary hypertension and improves angiogenic progenitor cell functions in experimental models. Am J Respir Crit Care Med (2013) 1.71
The angiotensin-converting enzyme 2/angiogenesis-(1-7)/Mas axis confers cardiopulmonary protection against lung fibrosis and pulmonary hypertension. Am J Respir Crit Care Med (2010) 1.64
Overexpression of angiotensin-converting enzyme 2 in the rostral ventrolateral medulla causes long-term decrease in blood pressure in the spontaneously hypertensive rats. Hypertension (2007) 1.63
Efficient large-scale production and concentration of HIV-1-based lentiviral vectors for use in vivo. Physiol Genomics (2003) 1.62
Moderate cardiac-selective overexpression of angiotensin II type 2 receptor protects cardiac functions from ischaemic injury. Exp Physiol (2011) 1.61
ACE2 gene transfer attenuates hypertension-linked pathophysiological changes in the SHR. Physiol Genomics (2006) 1.58
Thrombospondin 1 mediates angiotensin II induction of TGF-beta activation by cardiac and renal cells under both high and low glucose conditions. Biochem Biophys Res Commun (2005) 1.58
Structure-based identification of small-molecule angiotensin-converting enzyme 2 activators as novel antihypertensive agents. Hypertension (2008) 1.56
Connections of the retrosplenial granular b cortex in the rat. J Comp Neurol (2003) 1.52
Autonomic-immune-vascular interaction: an emerging concept for neurogenic hypertension. Hypertension (2011) 1.48
Analysis of drug prescription in chronic haemodialysis patients. Nephrol Dial Transplant (2002) 1.48
Hypocholesterolemia is a significant predictor of death in a cohort of chronic hemodialysis patients. Kidney Int (2002) 1.47
Therapeutic implications of the vasoprotective axis of the renin-angiotensin system in cardiovascular diseases. Hypertension (2009) 1.41
Superoxide dismutase mimetic, tempol, aggravates renal injury in advanced-stage stroke-prone spontaneously hypertensive rats. J Hypertens (2014) 1.38
Cardiac overexpression of angiotensin converting enzyme 2 protects the heart from ischemia-induced pathophysiology. Hypertension (2008) 1.37
NAD(P)H oxidase inhibition attenuates neuronal chronotropic actions of angiotensin II. Circ Res (2005) 1.36
Prevention of pulmonary hypertension by Angiotensin-converting enzyme 2 gene transfer. Hypertension (2009) 1.32
ACE2 and Ang-(1-7) confer protection against development of diabetic retinopathy. Mol Ther (2011) 1.32
ACE2: A novel therapeutic target for cardiovascular diseases. Prog Biophys Mol Biol (2005) 1.28
Accumulation of protein O-GlcNAc modification inhibits proteasomes in the brain and coincides with neuronal apoptosis in brain areas with high O-GlcNAc metabolism. J Neurochem (2004) 1.20
A thrombospondin-1 antagonist of transforming growth factor-beta activation blocks cardiomyopathy in rats with diabetes and elevated angiotensin II. Am J Pathol (2007) 1.20
Macrophage migration inhibitory factor: an intracellular inhibitor of angiotensin II-induced increases in neuronal activity. J Neurosci (2004) 1.20
ACE2 overexpression inhibits hypoxia-induced collagen production by cardiac fibroblasts. Clin Sci (Lond) (2007) 1.20
A current view of brain renin-angiotensin system: Is the (pro)renin receptor the missing link? Pharmacol Ther (2009) 1.19
Brain cytokines as neuromodulators in cardiovascular control. Clin Exp Pharmacol Physiol (2009) 1.18
Novel mechanism of brain soluble epoxide hydrolase-mediated blood pressure regulation in the spontaneously hypertensive rat. FASEB J (2005) 1.17
Characterization of a functional (pro)renin receptor in rat brain neurons. Exp Physiol (2008) 1.16
Perinatal loss of Nkx2-5 results in rapid conduction and contraction defects. Circ Res (2008) 1.16
Neuregulin-1beta induces neurite extension and arborization in cultured hippocampal neurons. Mol Cell Neurosci (2004) 1.16
Involvement of the brain (pro)renin receptor in cardiovascular homeostasis. Circ Res (2010) 1.14
Cloning and characterization of a secreted form of angiotensin-converting enzyme 2. Regul Pept (2004) 1.12
Identification of puerarin and its metabolites in rats by liquid chromatography-tandem mass spectrometry. J Agric Food Chem (2004) 1.11
Angiotensin-converting enzyme 2 activation protects against hypertension-induced cardiac fibrosis involving extracellular signal-regulated kinases. Exp Physiol (2010) 1.11
Neuregulin-1 and erbB4 immunoreactivity is associated with neuritic plaques in Alzheimer disease brain and in a transgenic model of Alzheimer disease. J Neuropathol Exp Neurol (2003) 1.10
Diminazene aceturate enhances angiotensin-converting enzyme 2 activity and attenuates ischemia-induced cardiac pathophysiology. Hypertension (2013) 1.07
Microdissection of neural networks by conditional reporter expression from a Brainbow herpesvirus. Proc Natl Acad Sci U S A (2011) 1.07
Effects of botanical dietary supplements on cardiovascular, cognitive, and metabolic function in males and females. Gend Med (2008) 1.07
The therapeutic potential of hepatocyte growth factor for myocardial infarction and heart failure. Curr Pharm Des (2004) 1.07
Angiotensin-converting enzyme 2 priming enhances the function of endothelial progenitor cells and their therapeutic efficacy. Hypertension (2012) 1.05
Lentivirus-mediated overexpression of angiotensin-(1-7) attenuated ischaemia-induced cardiac pathophysiology. Exp Physiol (2011) 1.04
Antihypertensive and cognitive effects of grape polyphenols in estrogen-depleted, female, spontaneously hypertensive rats. Am J Physiol Regul Integr Comp Physiol (2005) 1.04
ACE2 activation promotes antithrombotic activity. Mol Med (2010) 1.04
Angiotensin-(1-7) as an antihypertensive, antifibrotic target. Curr Hypertens Rep (2008) 1.03
Bone marrow-CNS connections: implications in the pathogenesis of diabetic retinopathy. Prog Retin Eye Res (2012) 1.01
Modulation of delayed rectifier potassium current by angiotensin II in CATH.a cells. Biochem Biophys Res Commun (2003) 1.01
Angiotensin-converting enzyme 2 activation improves endothelial function. Hypertension (2013) 0.98
Activation of the ACE2/angiotensin-(1-7)/Mas receptor axis enhances the reparative function of dysfunctional diabetic endothelial progenitors. Diabetes (2012) 0.98
ACE2, a promising therapeutic target for pulmonary hypertension. Curr Opin Pharmacol (2011) 0.97
Macrophage migration inhibitory factor in the PVN attenuates the central pressor and dipsogenic actions of angiotensin II. FASEB J (2006) 0.97
Contributions of vascular inflammation in the brainstem for neurogenic hypertension. Respir Physiol Neurobiol (2011) 0.97
Brain-mediated dysregulation of the bone marrow activity in angiotensin II-induced hypertension. Hypertension (2012) 0.95
Hypertension and prolonged vasoconstrictor signaling in RGS2-deficient mice. J Clin Invest (2003) 0.94
Retrosplenial cortex lesions of area Rgb (but not of area Rga) impair spatial learning and memory in the rat. Behav Brain Res (2004) 0.94
Species differences in the projections from the entorhinal cortex to the hippocampus. Brain Res Bull (2002) 0.94
Chronotropic action of angiotensin II in neurons via protein kinase C and CaMKII. Hypertension (2002) 0.94
Antiglaucomatous effects of the activation of intrinsic Angiotensin-converting enzyme 2. Invest Ophthalmol Vis Sci (2013) 0.94
Downregulation of p22phox in retinal pigment epithelial cells inhibits choroidal neovascularization in mice. Mol Ther (2008) 0.93
Apelin gene transfer into the rostral ventrolateral medulla induces chronic blood pressure elevation in normotensive rats. Circ Res (2009) 0.93
New cardiovascular and pulmonary therapeutic strategies based on the Angiotensin-converting enzyme 2/angiotensin-(1-7)/mas receptor axis. Int J Hypertens (2012) 0.93
Oral administration of an angiotensin-converting enzyme 2 activator ameliorates diabetes-induced cardiac dysfunction. Regul Pept (2012) 0.93
Perinatal taurine depletion increases susceptibility to adult sugar-induced hypertension in rats. Adv Exp Med Biol (2009) 0.93
The apolipoprotein A-I mimetic peptide 4F prevents defects in vascular function in endotoxemic rats. J Lipid Res (2010) 0.93
Altered inflammatory response is associated with an impaired autonomic input to the bone marrow in the spontaneously hypertensive rat. Hypertension (2013) 0.93
Angiotensin II causes imbalance between pro- and anti-inflammatory cytokines by modulating GSK-3β in neuronal culture. Br J Pharmacol (2013) 0.92
PI3-kinase inhibitors abolish the enhanced chronotropic effects of angiotensin II in spontaneously hypertensive rat brain neurons. J Neurophysiol (2003) 0.92
CNS inflammation and bone marrow neuropathy in type 1 diabetes. Am J Pathol (2013) 0.92
Potentiation of the antihypertensive action of losartan by peripheral overexpression of the ANG II type 2 receptor. Am J Physiol Heart Circ Physiol (2006) 0.92
Pharmacokinetic study of puerarin in rat serum by liquid chromatography tandem mass spectrometry. Biomed Chromatogr (2007) 0.91
Simultaneous determination of 11 phytoestrogens in human serum using a 2 min liquid chromatography/tandem mass spectrometry method. J Chromatogr B Analyt Technol Biomed Life Sci (2010) 0.90
Nucleus of the solitary tract (pro)renin receptor-mediated antihypertensive effect involves nuclear factor-κB-cytokine signaling in the spontaneously hypertensive rat. Hypertension (2013) 0.90
Perinatal taurine alters arterial pressure control and renal function in adult offspring. Adv Exp Med Biol (2009) 0.90
Are we poised to target ACE2 for the next generation of antihypertensives? J Mol Med (Berl) (2008) 0.90
The role of the laterodorsal nucleus of the thalamus in spatial learning and memory in the rat. Behav Brain Res (2002) 0.90
Area-specific differences in transmitter release in central catecholaminergic neurons of spontaneously hypertensive rats. Hypertension (2008) 0.90
Neurogenic hypertension. Exp Physiol (2010) 0.89
Selective silencing of angiotensin receptor subtype 1a (AT1aR) by RNA interference. Hypertension (2004) 0.89
Neurohormonal regulation of the sympathetic nervous system: new insights into central mechanisms of action. Curr Hypertens Rep (2008) 0.89
Genomic and proteomic approaches for targeting of angiotensin-converting enzyme2 for cardiovascular diseases. Curr Opin Cardiol (2008) 0.89
Curcuma comosa improves learning and memory function on ovariectomized rats in a long-term Morris water maze test. J Ethnopharmacol (2010) 0.89
Sex dependent effects of perinatal taurine exposure on the arterial pressure control in adult offspring. Adv Exp Med Biol (2009) 0.88
SMAD1 deficiency in either endothelial or smooth muscle cells can predispose mice to pulmonary hypertension. Hypertension (2013) 0.88
Excess dietary glucose alters renal function before increasing arterial pressure and inducing insulin resistance. Am J Hypertens (2002) 0.88
Angiotensin II type 2 receptor gene transfer elicits cardioprotective effects in an angiotensin II infusion rat model of hypertension. Physiol Genomics (2004) 0.88
Macrophage migration inhibitory factor in the paraventricular nucleus plays a major role in the sympathoexcitatory response to salt. Hypertension (2010) 0.88
The Chinese Pueraria root extract (Pueraria lobata) ameliorates impaired glucose and lipid metabolism in obese mice. Phytomedicine (2012) 0.88
Lack of macrophage migration inhibitory factor regulation is linked to the increased chronotropic action of angiotensin II in SHR neurons. Hypertension (2007) 0.88