Published in Circ Res on March 03, 2005
NADPH oxidases and angiotensin II receptor signaling. Mol Cell Endocrinol (2008) 2.22
Chemistry and antihypertensive effects of tempol and other nitroxides. Pharmacol Rev (2008) 1.91
Superoxide flux in endothelial cells via the chloride channel-3 mediates intracellular signaling. Mol Biol Cell (2007) 1.60
Sex differences in angiotensin signaling in bulbospinal neurons in the rat rostral ventrolateral medulla. Am J Physiol Regul Integr Comp Physiol (2008) 1.57
Genetic silencing of Nox2 and Nox4 reveals differential roles of these NADPH oxidase homologues in the vasopressor and dipsogenic effects of brain angiotensin II. Hypertension (2009) 1.45
Redox control of renal function and hypertension. Antioxid Redox Signal (2008) 1.45
Nox2 B-loop peptide, Nox2ds, specifically inhibits the NADPH oxidase Nox2. Free Radic Biol Med (2011) 1.27
Reactive oxygen species, NADPH oxidases, and hypertension. Hypertension (2010) 1.24
Angiotensin II and stretch activate NADPH oxidase to destabilize cardiac Kv4.3 channel mRNA. Circ Res (2006) 1.20
A current view of brain renin-angiotensin system: Is the (pro)renin receptor the missing link? Pharmacol Ther (2009) 1.19
Characterization of a functional (pro)renin receptor in rat brain neurons. Exp Physiol (2008) 1.16
Mitochondria-produced superoxide mediates angiotensin II-induced inhibition of neuronal potassium current. Am J Physiol Cell Physiol (2010) 1.14
Silencing nox4 in the paraventricular nucleus improves myocardial infarction-induced cardiac dysfunction by attenuating sympathoexcitation and periinfarct apoptosis. Circ Res (2010) 1.10
The attenuation of central angiotensin II-dependent pressor response and intra-neuronal signaling by intracarotid injection of nanoformulated copper/zinc superoxide dismutase. Biomaterials (2010) 1.04
Diminished A-type potassium current and altered firing properties in presympathetic PVN neurones in renovascular hypertensive rats. J Physiol (2008) 1.02
Mitochondrial-localized NADPH oxidase 4 is a source of superoxide in angiotensin II-stimulated neurons. Am J Physiol Heart Circ Physiol (2013) 1.00
Angiotensin II and angiotensin-1-7 redox signaling in the central nervous system. Curr Opin Pharmacol (2011) 1.00
In vivo bioluminescence imaging reveals redox-regulated activator protein-1 activation in paraventricular nucleus of mice with renovascular hypertension. Hypertension (2010) 0.96
Sex differences in the subcellular distribution of angiotensin type 1 receptors and NADPH oxidase subunits in the dendrites of C1 neurons in the rat rostral ventrolateral medulla. Neuroscience (2009) 0.95
Angiotensin II increases GABAB receptor expression in nucleus tractus solitarii of rats. Am J Physiol Heart Circ Physiol (2008) 0.91
Shift to an involvement of phosphatidylinositol 3-kinase in angiotensin II actions on nucleus tractus solitarii neurons of the spontaneously hypertensive rat. Circ Res (2009) 0.83
Regional expression of NAD(P)H oxidase and superoxide dismutase in the brain of rats with neurogenic hypertension. Am J Nephrol (2008) 0.83
Detraining differentially preserved beneficial effects of exercise on hypertension: effects on blood pressure, cardiac function, brain inflammatory cytokines and oxidative stress. PLoS One (2012) 0.81
Neuronal uptake of nanoformulated superoxide dismutase and attenuation of angiotensin II-dependent hypertension after central administration. Free Radic Biol Med (2014) 0.81
Angiotensin II, oxidant signaling, and hypertension: down to a T? Hypertension (2009) 0.80
Losartan improved respiratory function and coenzyme Q content in brain mitochondria of young spontaneously hypertensive rats. Cell Mol Neurobiol (2010) 0.79
Cross talk between AT1 receptors and Toll-like receptor 4 in microglia contributes to angiotensin II-derived ROS production in the hypothalamic paraventricular nucleus. Am J Physiol Heart Circ Physiol (2015) 0.79
NADPH Oxidase: A Potential Target for Treatment of Stroke. Oxid Med Cell Longev (2016) 0.78
Over-expressed copper/zinc superoxide dismutase localizes to mitochondria in neurons inhibiting the angiotensin II-mediated increase in mitochondrial superoxide. Redox Biol (2013) 0.78
Central command dysfunction in rats with heart failure is mediated by brain oxidative stress and normalized by exercise training. J Physiol (2014) 0.78
Angiotensin II-superoxide-NFκB signaling and aortic baroreceptor dysfunction in chronic heart failure. Front Neurosci (2015) 0.77
Macrophages in neuroinflammation: role of the renin-angiotensin-system. Pflugers Arch (2017) 0.77
Interleukin-10 inhibits angiotensin II-induced decrease in neuronal potassium current. Am J Physiol Cell Physiol (2013) 0.76
Novel Roles for Peroxynitrite in Angiotensin II and CaMKII Signaling. Sci Rep (2016) 0.75
Circulating angiotensin II deteriorates left ventricular function with sympathoexcitation via brain angiotensin II receptor. Physiol Rep (2015) 0.75
Novel mechanism within the paraventricular nucleus reduces both blood pressure and hypothalamic pituitary-adrenal axis responses to acute stress. Am J Physiol Heart Circ Physiol (2015) 0.75
Selective Nrf2 Gene Deletion in the Rostral Ventrolateral Medulla Evokes Hypertension and Sympathoexcitation in Mice. Hypertension (2017) 0.75
A-TYPE POTASSIUM CHANNELS CONTRIBUTE TO PRORENIN INCREASE OF FIRING ACTIVITY IN HYPOTHALAMIC VASOPRESSIN NEUROSECRETORY NEURONS. Am J Physiol Heart Circ Physiol (2017) 0.75
Evidence for angiotensin-converting enzyme 2 as a therapeutic target for the prevention of pulmonary hypertension. Am J Respir Crit Care Med (2009) 2.40
Circulating angiotensin II and dietary salt: converging signals for neurogenic hypertension. Curr Hypertens Rep (2007) 2.23
Prevention of angiotensin II-induced cardiac remodeling by angiotensin-(1-7). Am J Physiol Heart Circ Physiol (2006) 2.17
Real-time imaging of de novo arteriovenous malformation in a mouse model of hereditary hemorrhagic telangiectasia. J Clin Invest (2009) 2.13
Cerebroprotection by angiotensin-(1-7) in endothelin-1-induced ischaemic stroke. Exp Physiol (2011) 1.99
Brain microglial cytokines in neurogenic hypertension. Hypertension (2010) 1.97
Brain renin-angiotensin system dysfunction in hypertension: recent advances and perspectives. Br J Pharmacol (2003) 1.93
Protection from angiotensin II-induced cardiac hypertrophy and fibrosis by systemic lentiviral delivery of ACE2 in rats. Exp Physiol (2005) 1.85
Genetic ablation of the BMPR2 gene in pulmonary endothelium is sufficient to predispose to pulmonary arterial hypertension. Circulation (2008) 1.72
Diminazene attenuates pulmonary hypertension and improves angiogenic progenitor cell functions in experimental models. Am J Respir Crit Care Med (2013) 1.71
The angiotensin-converting enzyme 2/angiogenesis-(1-7)/Mas axis confers cardiopulmonary protection against lung fibrosis and pulmonary hypertension. Am J Respir Crit Care Med (2010) 1.64
Overexpression of angiotensin-converting enzyme 2 in the rostral ventrolateral medulla causes long-term decrease in blood pressure in the spontaneously hypertensive rats. Hypertension (2007) 1.63
Efficient large-scale production and concentration of HIV-1-based lentiviral vectors for use in vivo. Physiol Genomics (2003) 1.62
Moderate cardiac-selective overexpression of angiotensin II type 2 receptor protects cardiac functions from ischaemic injury. Exp Physiol (2011) 1.61
ACE2 gene transfer attenuates hypertension-linked pathophysiological changes in the SHR. Physiol Genomics (2006) 1.58
Structure-based identification of small-molecule angiotensin-converting enzyme 2 activators as novel antihypertensive agents. Hypertension (2008) 1.56
Autonomic-immune-vascular interaction: an emerging concept for neurogenic hypertension. Hypertension (2011) 1.48
Therapeutic implications of the vasoprotective axis of the renin-angiotensin system in cardiovascular diseases. Hypertension (2009) 1.41
Cardiac overexpression of angiotensin converting enzyme 2 protects the heart from ischemia-induced pathophysiology. Hypertension (2008) 1.37
Prevention of pulmonary hypertension by Angiotensin-converting enzyme 2 gene transfer. Hypertension (2009) 1.32
ACE2 and Ang-(1-7) confer protection against development of diabetic retinopathy. Mol Ther (2011) 1.32
ACE2: A novel therapeutic target for cardiovascular diseases. Prog Biophys Mol Biol (2005) 1.28
Candesartan pretreatment is cerebroprotective in a rat model of endothelin-1-induced middle cerebral artery occlusion. Exp Physiol (2009) 1.20
Macrophage migration inhibitory factor: an intracellular inhibitor of angiotensin II-induced increases in neuronal activity. J Neurosci (2004) 1.20
ACE2 overexpression inhibits hypoxia-induced collagen production by cardiac fibroblasts. Clin Sci (Lond) (2007) 1.20
A current view of brain renin-angiotensin system: Is the (pro)renin receptor the missing link? Pharmacol Ther (2009) 1.19
Brain cytokines as neuromodulators in cardiovascular control. Clin Exp Pharmacol Physiol (2009) 1.18
Effects of angiotensin type 2 receptor overexpression in the rostral ventrolateral medulla on blood pressure and urine excretion in normal rats. Hypertension (2007) 1.17
Novel mechanism of brain soluble epoxide hydrolase-mediated blood pressure regulation in the spontaneously hypertensive rat. FASEB J (2005) 1.17
Characterization of a functional (pro)renin receptor in rat brain neurons. Exp Physiol (2008) 1.16
Perinatal loss of Nkx2-5 results in rapid conduction and contraction defects. Circ Res (2008) 1.16
Cytokine-stimulated inducible nitric oxide synthase expression in astroglia: role of Erk mitogen-activated protein kinase and NF-kappaB. Glia (2003) 1.15
Involvement of the brain (pro)renin receptor in cardiovascular homeostasis. Circ Res (2010) 1.14
Cloning and characterization of a secreted form of angiotensin-converting enzyme 2. Regul Pept (2004) 1.12
Angiotensin-converting enzyme 2 activation protects against hypertension-induced cardiac fibrosis involving extracellular signal-regulated kinases. Exp Physiol (2010) 1.11
Macrophage migration inhibitory factor in hypothalamic paraventricular nucleus neurons decreases blood pressure in spontaneously hypertensive rats. FASEB J (2008) 1.07
Diminazene aceturate enhances angiotensin-converting enzyme 2 activity and attenuates ischemia-induced cardiac pathophysiology. Hypertension (2013) 1.07
Microdissection of neural networks by conditional reporter expression from a Brainbow herpesvirus. Proc Natl Acad Sci U S A (2011) 1.07
Angiotensin-converting enzyme 2 priming enhances the function of endothelial progenitor cells and their therapeutic efficacy. Hypertension (2012) 1.05
Lentivirus-mediated overexpression of angiotensin-(1-7) attenuated ischaemia-induced cardiac pathophysiology. Exp Physiol (2011) 1.04
Anti-inflammatory effects of angiotensin-(1-7) in ischemic stroke. Neuropharmacology (2013) 1.04
ACE2 activation promotes antithrombotic activity. Mol Med (2010) 1.04
Angiotensin-(1-7) as an antihypertensive, antifibrotic target. Curr Hypertens Rep (2008) 1.03
Bone marrow-CNS connections: implications in the pathogenesis of diabetic retinopathy. Prog Retin Eye Res (2012) 1.01
Modulation of delayed rectifier potassium current by angiotensin II in CATH.a cells. Biochem Biophys Res Commun (2003) 1.01
Immunostaining evidence for PI(4,5)P2 localization at the leading edge of chemoattractant-stimulated HL-60 cells. J Leukoc Biol (2008) 1.01
Centrally administered angiotensin-(1-7) increases the survival of stroke-prone spontaneously hypertensive rats. Exp Physiol (2013) 1.01
Increased PI3-kinase in presympathetic brain areas of the spontaneously hypertensive rat. Circ Res (2005) 0.99
Angiotensin-converting enzyme 2 activation improves endothelial function. Hypertension (2013) 0.98
Activation of the ACE2/angiotensin-(1-7)/Mas receptor axis enhances the reparative function of dysfunctional diabetic endothelial progenitors. Diabetes (2012) 0.98
Angiotensin type 1a receptors in the paraventricular nucleus of the hypothalamus protect against diet-induced obesity. J Neurosci (2013) 0.97
Endocrine and neurobehavioral abnormalities induced by propofol administered to neonatal rats. Anesthesiology (2014) 0.97
Contributions of vascular inflammation in the brainstem for neurogenic hypertension. Respir Physiol Neurobiol (2011) 0.97
Macrophage migration inhibitory factor in the PVN attenuates the central pressor and dipsogenic actions of angiotensin II. FASEB J (2006) 0.97
Recombinant adeno-associated virus serotype 2 effectively transduces primary rat brain astrocytes and microglia. Brain Res Brain Res Protoc (2004) 0.97
ACE2, a promising therapeutic target for pulmonary hypertension. Curr Opin Pharmacol (2011) 0.97
Brain-mediated dysregulation of the bone marrow activity in angiotensin II-induced hypertension. Hypertension (2012) 0.95
Angiotensin type 2 receptor-mediated apoptosis of human prostate cancer cells. Mol Cancer Ther (2009) 0.95
Chronotropic action of angiotensin II in neurons via protein kinase C and CaMKII. Hypertension (2002) 0.94
Antiglaucomatous effects of the activation of intrinsic Angiotensin-converting enzyme 2. Invest Ophthalmol Vis Sci (2013) 0.94
Downregulation of p22phox in retinal pigment epithelial cells inhibits choroidal neovascularization in mice. Mol Ther (2008) 0.93
Apelin gene transfer into the rostral ventrolateral medulla induces chronic blood pressure elevation in normotensive rats. Circ Res (2009) 0.93
Oral administration of an angiotensin-converting enzyme 2 activator ameliorates diabetes-induced cardiac dysfunction. Regul Pept (2012) 0.93
Altered inflammatory response is associated with an impaired autonomic input to the bone marrow in the spontaneously hypertensive rat. Hypertension (2013) 0.93
New cardiovascular and pulmonary therapeutic strategies based on the Angiotensin-converting enzyme 2/angiotensin-(1-7)/mas receptor axis. Int J Hypertens (2012) 0.93
PI3-kinase inhibitors abolish the enhanced chronotropic effects of angiotensin II in spontaneously hypertensive rat brain neurons. J Neurophysiol (2003) 0.92
Potentiation of the antihypertensive action of losartan by peripheral overexpression of the ANG II type 2 receptor. Am J Physiol Heart Circ Physiol (2006) 0.92
CNS inflammation and bone marrow neuropathy in type 1 diabetes. Am J Pathol (2013) 0.92
Angiotensin II causes imbalance between pro- and anti-inflammatory cytokines by modulating GSK-3β in neuronal culture. Br J Pharmacol (2013) 0.92
Drinking behavior elicited by central injection of angiotensin II: roles for protein kinase C and Ca2+/calmodulin-dependent protein kinase II. Am J Physiol Regul Integr Comp Physiol (2003) 0.91
Angiotensin II increases GABAB receptor expression in nucleus tractus solitarii of rats. Am J Physiol Heart Circ Physiol (2008) 0.91
Selective tropism of the recombinant adeno-associated virus 9 serotype for rat cardiac tissue. J Gene Med (2010) 0.90
Role of prolylcarboxypeptidase in angiotensin II type 2 receptor-mediated bradykinin release in mouse coronary artery endothelial cells. Hypertension (2010) 0.90
Nucleus of the solitary tract (pro)renin receptor-mediated antihypertensive effect involves nuclear factor-κB-cytokine signaling in the spontaneously hypertensive rat. Hypertension (2013) 0.90
Are we poised to target ACE2 for the next generation of antihypertensives? J Mol Med (Berl) (2008) 0.90
Area-specific differences in transmitter release in central catecholaminergic neurons of spontaneously hypertensive rats. Hypertension (2008) 0.90
Neurogenic hypertension. Exp Physiol (2010) 0.89
Selective silencing of angiotensin receptor subtype 1a (AT1aR) by RNA interference. Hypertension (2004) 0.89
Genomic and proteomic approaches for targeting of angiotensin-converting enzyme2 for cardiovascular diseases. Curr Opin Cardiol (2008) 0.89
Macrophage migration inhibitory factor in the paraventricular nucleus plays a major role in the sympathoexcitatory response to salt. Hypertension (2010) 0.88
SMAD1 deficiency in either endothelial or smooth muscle cells can predispose mice to pulmonary hypertension. Hypertension (2013) 0.88