PubRank

Roger D Cone

Author PubWeight™ 82.61‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Gut hormone PYY(3-36) physiologically inhibits food intake. Nature 2002 8.30
2 The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis. Neuron 2003 6.05
3 Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor. Nat Neurosci 2003 4.83
4 Activation of central melanocortin pathways by fenfluramine. Science 2002 2.71
5 Fasting induces a large, leptin-dependent increase in the intrinsic action potential frequency of orexigenic arcuate nucleus neuropeptide Y/Agouti-related protein neurons. Endocrinology 2004 2.15
6 Cholecystokinin-mediated suppression of feeding involves the brainstem melanocortin system. Nat Neurosci 2004 2.14
7 Peptide YY3-36 inhibits food intake in mice through a melanocortin-4 receptor-independent mechanism. Endocrinology 2004 1.80
8 Effect of Agouti-related protein in regulation of the hypothalamic-pituitary-thyroid axis in the melanocortin 4 receptor knockout mouse. Endocrinology 2004 1.71
9 Role of the central melanocortin circuitry in adaptive thermogenesis of brown adipose tissue. Endocrinology 2006 1.71
10 The central melanocortin system and the integration of short- and long-term regulators of energy homeostasis. Recent Prog Horm Res 2004 1.60
11 Neuropeptide W: an anorectic peptide regulated by leptin and metabolic state. Endocrinology 2010 1.50
12 The melanocortin-3 receptor is required for entrainment to meal intake. J Neurosci 2008 1.49
13 Characterization of a novel binding partner of the melanocortin-4 receptor: attractin-like protein. Biochem J 2003 1.49
14 Melanocortin-4 receptor signaling is required for weight loss after gastric bypass surgery. J Clin Endocrinol Metab 2012 1.46
15 Creation of a genetic model of obesity in a teleost. FASEB J 2007 1.35
16 A role for the endogenous opioid beta-endorphin in energy homeostasis. Endocrinology 2003 1.31
17 The regulation of food intake by selective stimulation of the type 3 melanocortin receptor (MC3R). Peptides 2005 1.31
18 Role of leptin and melanocortin signaling in uremia-associated cachexia. J Clin Invest 2005 1.30
19 Characterization of leptin-responsive neurons in the caudal brainstem. Endocrinology 2006 1.30
20 Peripheral administration of PYY(3-36) produces conditioned taste aversion in mice. Cell Metab 2005 1.29
21 Pineal-specific agouti protein regulates teleost background adaptation. Proc Natl Acad Sci U S A 2010 1.27
22 Obesity-induced inflammation in white adipose tissue is attenuated by loss of melanocortin-3 receptor signaling. Endocrinology 2007 1.24
23 Central serotonin and melanocortin pathways regulating energy homeostasis. Ann N Y Acad Sci 2003 1.24
24 Multinodal regulation of the arcuate/paraventricular nucleus circuit by leptin. Proc Natl Acad Sci U S A 2010 1.20
25 Genetic disruption of gamma-melanocyte-stimulating hormone signaling leads to salt-sensitive hypertension in the mouse. J Clin Invest 2003 1.17
26 The role of the central melanocortin system in the regulation of food intake and energy homeostasis: lessons from mouse models. Philos Trans R Soc Lond B Biol Sci 2006 1.14
27 Central receptors mediating the cardiovascular actions of melanocyte stimulating hormones. J Hypertens 2006 1.12
28 Differential role of melanocortin receptor subtypes in cachexia. Endocrinology 2003 1.10
29 Knockout studies defining different roles for melanocortin receptors in energy homeostasis. Ann N Y Acad Sci 2003 1.10
30 Characterization of the hyperphagic response to dietary fat in the MC4R knockout mouse. Endocrinology 2011 1.09
31 Developmental control of the melanocortin-4 receptor by MRAP2 proteins in zebrafish. Science 2013 1.03
32 Agouti-related protein (AGRP) is conserved and regulated by metabolic state in the zebrafish, Danio rerio. Endocrine 2003 1.00
33 Interactions between gut peptides and the central melanocortin system in the regulation of energy homeostasis. Peptides 2005 0.99
34 Conserved neurochemical pathways involved in hypothalamic control of energy homeostasis. J Comp Neurol 2007 0.99
35 AgRP and POMC neurons are hypophysiotropic and coordinately regulate multiple endocrine axes in a larval teleost. Cell Metab 2012 0.98
36 Melanocortin-3 receptor regulates the normal fasting response. Proc Natl Acad Sci U S A 2012 0.97
37 Melanocortin-4 receptor mutations paradoxically reduce preference for palatable foods. Proc Natl Acad Sci U S A 2013 0.95
38 Physiological roles of the melanocortin MC₃ receptor. Eur J Pharmacol 2011 0.94
39 RM-493, a melanocortin-4 receptor (MC4R) agonist, increases resting energy expenditure in obese individuals. J Clin Endocrinol Metab 2015 0.94
40 Melanocortin-5 receptor deficiency promotes defensive behavior in male mice. Horm Behav 2004 0.93
41 Regulation of thyrotropin-releasing hormone-expressing neurons in paraventricular nucleus of the hypothalamus by signals of adiposity. Mol Endocrinol 2010 0.91
42 Mechanisms of disease: Cytokine and adipokine signaling in uremic cachexia. Nat Clin Pract Nephrol 2006 0.90
43 Orexigenic and anorexigenic mechanisms in the control of nutrition in chronic kidney disease. Pediatr Nephrol 2005 0.90
44 Ala67Thr polymorphism in the Agouti-related peptide gene is associated with inherited leanness in humans. Am J Med Genet A 2004 0.89
45 Development of a high throughput screen for allosteric modulators of melanocortin-4 receptor signaling using a real time cAMP assay. Eur J Pharmacol 2011 0.89
46 Gender-specific roles for the melanocortin-3 receptor in the regulation of the mesolimbic dopamine system in mice. Endocrinology 2014 0.89
47 Melanocortin-5 receptor deficiency in mice blocks a novel pathway influencing pheromone-induced aggression. Behav Genet 2006 0.88
48 Melanocortin-5 receptor deficiency reduces a pheromonal signal for aggression in male mice. Chem Senses 2004 0.87
49 PYY3-36 inhibits the action potential firing activity of POMC neurons of arcuate nucleus through postsynaptic Y2 receptors. Cell Metab 2005 0.84
50 The anorexigenic fatty acid synthase inhibitor, C75, is a nonspecific neuronal activator. Endocrinology 2003 0.84
51 The role of the melanocortin-3 receptor in cachexia. Ann N Y Acad Sci 2003 0.83
52 Assessment of a small molecule melanocortin-4 receptor-specific agonist on energy homeostasis. Brain Res 2004 0.81
53 Reply to Braasch and Postlethwait: Evolutionary origin of the teleost A2 agouti genes (agouti signaling protein 2 and agouti-related protein 2) remains unclear. Proc Natl Acad Sci U S A 2011 0.79
54 Development of an assay for high-throughput energy expenditure monitoring in the zebrafish. Zebrafish 2013 0.78
55 Pheromone-induced anorexia in male Syrian hamsters. Am J Physiol Endocrinol Metab 2003 0.77
56 De novo design, synthesis, and pharmacology of alpha-melanocyte stimulating hormone analogues derived from somatostatin by a hybrid approach. J Med Chem 2004 0.77
57 Shining a light on energy homeostasis. Cell Metab 2011 0.76
58 Zebrafish ghrelin is expressed in pancreatic endocrine cells and regulated by metabolic state. Biochem Biophys Res Commun 2013 0.76
59 Neuropeptide Y and gamma-melanocyte stimulating hormone (gamma-MSH) share a common pressor mechanism of action. Endocrine 2009 0.75
60 QnAs with Roger D. Cone. Proc Natl Acad Sci U S A 2013 0.75