Published in Crit Rev Eukaryot Gene Expr on January 01, 2004
Defining the impact of beta-catenin/Tcf transactivation on epithelial stem cells. Genes Dev (2005) 3.67
The basic science of tendinopathy. Clin Orthop Relat Res (2008) 1.37
Proteoglycomics: recent progress and future challenges. OMICS (2010) 1.25
Biglycan: a multivalent proteoglycan providing structure and signals. J Histochem Cytochem (2012) 1.12
Biglycan enhances gastric cancer invasion by activating FAK signaling pathway. Oncotarget (2014) 0.96
Aptamer-based proteomic signature of intensive phase treatment response in pulmonary tuberculosis. Tuberculosis (Edinb) (2014) 0.90
Impaired posterior frontal sutural fusion in the biglycan/decorin double deficient mice. Bone (2006) 0.85
A mouse model of spontaneous preterm birth based on the genetic ablation of biglycan and decorin. Reproduction (2011) 0.83
Asporin Is a Fibroblast-Derived TGF-β1 Inhibitor and a Tumor Suppressor Associated with Good Prognosis in Breast Cancer. PLoS Med (2015) 0.82
High expression of biglycan is associated with poor prognosis in patients with esophageal squamous cell carcinoma. Int J Clin Exp Pathol (2013) 0.81
Uterine dysfunction in biglycan and decorin deficient mice leads to dystocia during parturition. PLoS One (2012) 0.77
Extracellular Matrix Mediates BMP-2 in a Model of Temporomandibular Joint Osteoarthritis. Cells Tissues Organs (2017) 0.75
Identification of tendon stem/progenitor cells and the role of the extracellular matrix in their niche. Nat Med (2007) 4.80
The matrix component biglycan is proinflammatory and signals through Toll-like receptors 4 and 2 in macrophages. J Clin Invest (2005) 3.99
Mice deficient in small leucine-rich proteoglycans: novel in vivo models for osteoporosis, osteoarthritis, Ehlers-Danlos syndrome, muscular dystrophy, and corneal diseases. Glycobiology (2002) 2.46
Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors. J Biol Chem (2009) 2.12
The proteoglycan biglycan regulates expression of the B cell chemoattractant CXCL13 and aggravates murine lupus nephritis. J Clin Invest (2010) 2.07
Abnormal collagen fibrils in tendons of biglycan/fibromodulin-deficient mice lead to gait impairment, ectopic ossification, and osteoarthritis. FASEB J (2002) 2.05
Biglycan deficiency causes spontaneous aortic dissection and rupture in mice. Circulation (2007) 1.98
deltaNp63alpha functions as both a positive and a negative transcriptional regulator and blocks in vitro differentiation of murine keratinocytes. Oncogene (2003) 1.92
Modulation of canonical Wnt signaling by the extracellular matrix component biglycan. Proc Natl Acad Sci U S A (2011) 1.85
Extracellular matrix proteoglycans control the fate of bone marrow stromal cells. J Biol Chem (2005) 1.82
Genetic evidence for the coordinated regulation of collagen fibrillogenesis in the cornea by decorin and biglycan. J Biol Chem (2009) 1.79
Hedgehog signaling in mature osteoblasts regulates bone formation and resorption by controlling PTHrP and RANKL expression. Dev Cell (2008) 1.76
The small leucine-rich proteoglycan biglycan modulates BMP-4-induced osteoblast differentiation. FASEB J (2004) 1.74
The effect of 3D hydrogel scaffold modulus on osteoblast differentiation and mineralization revealed by combinatorial screening. Biomaterials (2010) 1.71
A crucial role of caspase-3 in osteogenic differentiation of bone marrow stromal stem cells. J Clin Invest (2004) 1.71
Pharmacologic stem cell based intervention as a new approach to osteoporosis treatment in rodents. PLoS One (2008) 1.60
Osteoblast-related transcription factors Runx2 (Cbfa1/AML3) and MSX2 mediate the expression of bone sialoprotein in human metastatic breast cancer cells. Cancer Res (2003) 1.57
Exercise-induced changes in the cortical bone of growing mice are bone- and gender-specific. Bone (2007) 1.52
Biglycan knockout mice: new models for musculoskeletal diseases. Glycoconj J (2003) 1.32
Decorin deficiency leads to impaired angiogenesis in injured mouse cornea. J Vasc Res (2004) 1.29
Age-related osteoporosis in biglycan-deficient mice is related to defects in bone marrow stromal cells. J Bone Miner Res (2002) 1.29
Animal models of osteoarthritis: lessons learned while seeking the "Holy Grail". Curr Opin Rheumatol (2006) 1.27
The determination of stem cell fate by 3D scaffold structures through the control of cell shape. Biomaterials (2011) 1.25
WISP-1/CCN4 regulates osteogenesis by enhancing BMP-2 activity. J Bone Miner Res (2011) 1.23
Mice deficient in biglycan and fibromodulin as a model for temporomandibular joint osteoarthritis. Cells Tissues Organs (2005) 1.16
Modulus-driven differentiation of marrow stromal cells in 3D scaffolds that is independent of myosin-based cytoskeletal tension. Biomaterials (2010) 1.14
Defective osteogenesis of the stromal stem cells predisposes CD18-null mice to osteoporosis. Proc Natl Acad Sci U S A (2005) 1.13
Biglycan and fibromodulin have essential roles in regulating chondrogenesis and extracellular matrix turnover in temporomandibular joint osteoarthritis. Am J Pathol (2009) 1.13
Impact on bone of an estrogen receptor-alpha gene loss of function mutation. J Clin Endocrinol Metab (2008) 1.12
Biglycan: a multivalent proteoglycan providing structure and signals. J Histochem Cytochem (2012) 1.12
Does endotoxin contribute to aseptic loosening of orthopedic implants? J Biomed Mater Res B Appl Biomater (2005) 1.11
Fibromodulin-deficient mice display impaired collagen fibrillogenesis in predentin as well as altered dentin mineralization and enamel formation. J Histochem Cytochem (2005) 1.11
Transient up-regulation of biglycan during skeletal muscle regeneration: delayed fiber growth along with decorin increase in biglycan-deficient mice. Dev Biol (2004) 1.10
Deficiency of biglycan causes cardiac fibroblasts to differentiate into a myofibroblast phenotype. J Biol Chem (2011) 1.10
The mechanical phenotype of biglycan-deficient mice is bone- and gender-specific. Bone (2006) 1.09
Mesenchymal stem cell-mediated ectopic hematopoiesis alleviates aging-related phenotype in immunocompromised mice. Blood (2008) 1.05
The biology of small leucine-rich proteoglycans in bone pathophysiology. J Biol Chem (2012) 1.04
TGF-beta1 and WISP-1/CCN-4 can regulate each other's activity to cooperatively control osteoblast function. J Cell Biochem (2008) 1.03
Regulation of fibrillin-1 by biglycan and decorin is important for tissue preservation in the kidney during pressure-induced injury. Am J Pathol (2004) 1.03
Biglycan is an extracellular MuSK binding protein important for synapse stability. J Neurosci (2012) 1.02
Cytokines synergistically induce osteoclast differentiation: support by immortalized or normal calvarial cells. Am J Physiol Cell Physiol (2002) 1.02
Variation in mineral properties in normal and mutant bones and teeth. Cells Tissues Organs (2005) 0.98
Combinatorial screening of osteoblast response to 3D calcium phosphate/poly(ε-caprolactone) scaffolds using gradients and arrays. Biomaterials (2010) 0.98
Regeneration of bone and periodontal ligament induced by recombinant amelogenin after periodontitis. J Cell Mol Med (2009) 0.96
WISP1/CCN4: a potential target for inhibiting prostate cancer growth and spread to bone. PLoS One (2013) 0.95
Biglycan binds to alpha- and gamma-sarcoglycan and regulates their expression during development. J Cell Physiol (2006) 0.94
Genetic evidence for key roles of decorin and biglycan in dentin mineralization. Matrix Biol (2009) 0.94
The proteoglycan biglycan enhances antigen-specific T cell activation potentially via MyD88 and TRIF pathways and triggers autoimmune perimyocarditis. J Immunol (2011) 0.92
Absence of biglycan accelerates the degenerative process in mouse intervertebral disc. Spine (Phila Pa 1976) (2009) 0.92
Biglycan deficiency increases osteoclast differentiation and activity due to defective osteoblasts. Bone (2005) 0.91
The potential functional interaction of biglycan and WISP-1 in controlling differentiation and proliferation of osteogenic cells. Cells Tissues Organs (2008) 0.90
Biglycan deficiency interferes with ovariectomy-induced bone loss. J Bone Miner Res (2003) 0.90
Fibromodulin-deficient mice reveal dual functions for fibromodulin in regulating dental tissue and alveolar bone formation. Cells Tissues Organs (2008) 0.89
Gene expression profile of human bone marrow stromal cells: high-throughput expressed sequence tag sequencing analysis. Genomics (2002) 0.89
Freeform fabricated scaffolds with roughened struts that enhance both stem cell proliferation and differentiation by controlling cell shape. Biomaterials (2012) 0.89
Nanofiber scaffold gradients for interfacial tissue engineering. J Biomater Appl (2012) 0.87
Impaired posterior frontal sutural fusion in the biglycan/decorin double deficient mice. Bone (2006) 0.85
Musculoskeletal tissue engineering by endogenous stem/progenitor cells. Cell Tissue Res (2012) 0.83
Fabricating gradient hydrogel scaffolds for 3D cell culture. Comb Chem High Throughput Screen (2011) 0.81
Tendon functional extracellular matrix. J Orthop Res (2015) 0.81
Dentin and dental pulp regeneration by the patient's endogenous cells. Endod Topics (2013) 0.80
Characterization of dental pulp defect and repair in a canine model. Am J Dent (2011) 0.80
Dissection of the sets of genes that control the behavior of biglycan-deficient pre-osteoblasts using oligonucleotide microarrays. Bone (2005) 0.79
Transcriptional regulation restricting bone sialoprotein gene expression to both hypertrophic chondrocytes and osteoblasts. J Cell Biochem (2002) 0.79
Expression of transcription factors and matrix genes in response to serum stimulus in vascular smooth muscle cells. Eur J Cell Biol (2003) 0.76
The small leucine-rich proteoglycan BGN accumulates in CADASIL and binds to NOTCH3. Transl Stroke Res (2015) 0.75
Engineered nasal cartilage by cell homing: a model for augmentative and reconstructive rhinoplasty. Plast Reconstr Surg (2014) 0.75
Periodontal Ligament and Alveolar Bone in Health and Adaptation: Tooth Movement. Front Oral Biol (2015) 0.75
Extracellular Matrix Mediates BMP-2 in a Model of Temporomandibular Joint Osteoarthritis. Cells Tissues Organs (2017) 0.75