Published in Spine (Phila Pa 1976) on December 01, 2009
Decorin expression is important for age-related changes in tendon structure and mechanical properties. Matrix Biol (2012) 1.39
Non-enzymatic decomposition of collagen fibers by a biglycan antibody and a plausible mechanism for rheumatoid arthritis. PLoS One (2012) 0.90
Molecular mechanisms of biological aging in intervertebral discs. J Orthop Res (2016) 0.85
Potential use of human adipose mesenchymal stromal cells for intervertebral disc regeneration: a preliminary study on biglycan-deficient murine model of chronic disc degeneration. Arthritis Res Ther (2014) 0.81
Small leucine-rich proteoglycans exhibit unique spatiotemporal expression profiles during cardiac valve development. Dev Dyn (2014) 0.79
Mohawk promotes the maintenance and regeneration of the outer annulus fibrosus of intervertebral discs. Nat Commun (2016) 0.78
The aging mouse partially models the aging human spine: lumbar and coccygeal disc height, composition, mechanical properties, and Wnt signaling in young and old mice. J Appl Physiol (1985) (2014) 0.77
Differentiation of immortalized human precartilaginous stem cells into nucleus pulposus-like cells. Int J Clin Exp Pathol (2015) 0.75
Evidence for an Important Role of Smad-7 in Intervertebral Disc Degeneration. J Interferon Cytokine Res (2015) 0.75
Magnetic resonance imaging of the lumbar spine in people without back pain. N Engl J Med (1994) 11.46
Abnormal magnetic-resonance scans of the lumbar spine in asymptomatic subjects. A prospective investigation. J Bone Joint Surg Am (1990) 8.22
Negative regulation of transforming growth factor-beta by the proteoglycan decorin. Nature (1990) 4.90
Classification of age-related changes in lumbar intervertebral discs: 2002 Volvo Award in basic science. Spine (Phila Pa 1976) (2002) 4.39
Interaction of the small interstitial proteoglycans biglycan, decorin and fibromodulin with transforming growth factor beta. Biochem J (1994) 3.92
An aspartic acid repeat polymorphism in asporin inhibits chondrogenesis and increases susceptibility to osteoarthritis. Nat Genet (2005) 3.00
Targeted disruption of the biglycan gene leads to an osteoporosis-like phenotype in mice. Nat Genet (1998) 2.84
Mice deficient in small leucine-rich proteoglycans: novel in vivo models for osteoporosis, osteoarthritis, Ehlers-Danlos syndrome, muscular dystrophy, and corneal diseases. Glycobiology (2002) 2.46
A slowly progressive and reproducible animal model of intervertebral disc degeneration characterized by MRI, X-ray, and histology. Spine (Phila Pa 1976) (2005) 2.14
Abnormal collagen fibrils in tendons of biglycan/fibromodulin-deficient mice lead to gait impairment, ectopic ossification, and osteoarthritis. FASEB J (2002) 2.05
Leucine-rich repeat glycoproteins of the extracellular matrix. Matrix Biol (1998) 2.02
The small leucine-rich proteoglycan biglycan modulates BMP-4-induced osteoblast differentiation. FASEB J (2004) 1.74
Complexes of matrilin-1 and biglycan or decorin connect collagen VI microfibrils to both collagen II and aggrecan. J Biol Chem (2003) 1.72
Changes in mRNA and protein levels of proteoglycans of the anulus fibrosus and nucleus pulposus during intervertebral disc degeneration. Spine (Phila Pa 1976) (2002) 1.42
Age-related osteoporosis in biglycan-deficient mice is related to defects in bone marrow stromal cells. J Bone Miner Res (2002) 1.29
Two novel matrix proteins isolated from articular cartilage show wide distributions among connective tissues. J Biol Chem (1986) 1.27
Inverse relation between osteoporosis and spondylosis in postmenopausal women as evaluated by bone mineral density and semiquantitative scoring of spinal degeneration. Spine (Phila Pa 1976) (2003) 1.26
Radiographic features of lumbar disc degeneration and bone mineral density in men and women. Ann Rheum Dis (2005) 1.22
Relative increase of biglycan and decorin and altered chondroitin sulfate epitopes in the degenerating human intervertebral disc. J Rheumatol (1998) 1.11
Decorin core protein fragment Leu155-Val260 interacts with TGF-beta but does not compete for decorin binding to type I collagen. Arch Biochem Biophys (1998) 1.09
Non-proteoglycan forms of biglycan increase with age in human articular cartilage. Biochem J (1993) 1.08
Identification and characterization of glycanated and non-glycanated forms of biglycan and decorin in the human intervertebral disc. Biochem J (1993) 1.06
Correlation between bone mineral density and intervertebral disc degeneration. Spine (Phila Pa 1976) (1998) 1.04
Correlation between bone mineral density and intervertebral disk degeneration in pre- and postmenopausal women. J Bone Miner Metab (2003) 0.88
Analysis of changes in proteoglycan content in murine articular cartilage using image analysis. Osteoarthritis Cartilage (1994) 0.79
Identification of tendon stem/progenitor cells and the role of the extracellular matrix in their niche. Nat Med (2007) 4.80
The matrix component biglycan is proinflammatory and signals through Toll-like receptors 4 and 2 in macrophages. J Clin Invest (2005) 3.99
Mice deficient in small leucine-rich proteoglycans: novel in vivo models for osteoporosis, osteoarthritis, Ehlers-Danlos syndrome, muscular dystrophy, and corneal diseases. Glycobiology (2002) 2.46
Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors. J Biol Chem (2009) 2.12
The proteoglycan biglycan regulates expression of the B cell chemoattractant CXCL13 and aggravates murine lupus nephritis. J Clin Invest (2010) 2.07
Abnormal collagen fibrils in tendons of biglycan/fibromodulin-deficient mice lead to gait impairment, ectopic ossification, and osteoarthritis. FASEB J (2002) 2.05
Biglycan deficiency causes spontaneous aortic dissection and rupture in mice. Circulation (2007) 1.98
deltaNp63alpha functions as both a positive and a negative transcriptional regulator and blocks in vitro differentiation of murine keratinocytes. Oncogene (2003) 1.92
Modulation of canonical Wnt signaling by the extracellular matrix component biglycan. Proc Natl Acad Sci U S A (2011) 1.85
Extracellular matrix proteoglycans control the fate of bone marrow stromal cells. J Biol Chem (2005) 1.82
Genetic evidence for the coordinated regulation of collagen fibrillogenesis in the cornea by decorin and biglycan. J Biol Chem (2009) 1.79
The small leucine-rich proteoglycan biglycan modulates BMP-4-induced osteoblast differentiation. FASEB J (2004) 1.74
The effect of 3D hydrogel scaffold modulus on osteoblast differentiation and mineralization revealed by combinatorial screening. Biomaterials (2010) 1.71
Osteoblast-related transcription factors Runx2 (Cbfa1/AML3) and MSX2 mediate the expression of bone sialoprotein in human metastatic breast cancer cells. Cancer Res (2003) 1.57
Exercise-induced changes in the cortical bone of growing mice are bone- and gender-specific. Bone (2007) 1.52
Effect of platelet-rich plasma with fibrin matrix on healing of intrasynovial flexor tendons. J Hand Surg Am (2012) 1.47
Classification, treatment, and outcome of osteochondritis dissecans of the humeral capitellum. J Bone Joint Surg Am (2007) 1.46
Reoperative coronary artery bypass surgery: avoiding repeat median sternotomy. Ann Thorac Surg (2012) 1.43
Modified digital tourniquet designed to prevent the tourniquet from inadvertently being left in place after the end of surgery. J Orthop Trauma (2010) 1.39
Loss-of-function mutations in PTPN11 cause metachondromatosis, but not Ollier disease or Maffucci syndrome. PLoS Genet (2011) 1.34
Decorin deficiency leads to impaired angiogenesis in injured mouse cornea. J Vasc Res (2004) 1.29
Age-related osteoporosis in biglycan-deficient mice is related to defects in bone marrow stromal cells. J Bone Miner Res (2002) 1.29
Animal models of osteoarthritis: lessons learned while seeking the "Holy Grail". Curr Opin Rheumatol (2006) 1.27
The determination of stem cell fate by 3D scaffold structures through the control of cell shape. Biomaterials (2011) 1.25
WISP-1/CCN4 regulates osteogenesis by enhancing BMP-2 activity. J Bone Miner Res (2011) 1.23
Long-term clinical and radiographic outcomes after open reduction for missed Monteggia fracture-dislocations in children. J Bone Joint Surg Am (2009) 1.21
Mice deficient in biglycan and fibromodulin as a model for temporomandibular joint osteoarthritis. Cells Tissues Organs (2005) 1.16
Effect of axitinib (AG-013736) on fatigue, thyroid-stimulating hormone, and biomarkers: a phase I study in Japanese patients. Cancer Sci (2009) 1.14
Modulus-driven differentiation of marrow stromal cells in 3D scaffolds that is independent of myosin-based cytoskeletal tension. Biomaterials (2010) 1.14
Risk factors for elbow injuries among young baseball players. J Shoulder Elbow Surg (2010) 1.13
Biglycan and fibromodulin have essential roles in regulating chondrogenesis and extracellular matrix turnover in temporomandibular joint osteoarthritis. Am J Pathol (2009) 1.13
Impact on bone of an estrogen receptor-alpha gene loss of function mutation. J Clin Endocrinol Metab (2008) 1.12
A diagnostic support tool for lumbar spinal stenosis: a self-administered, self-reported history questionnaire. BMC Musculoskelet Disord (2007) 1.12
Biglycan: a multivalent proteoglycan providing structure and signals. J Histochem Cytochem (2012) 1.12
Fibromodulin-deficient mice display impaired collagen fibrillogenesis in predentin as well as altered dentin mineralization and enamel formation. J Histochem Cytochem (2005) 1.11
Engineered allogeneic mesenchymal stem cells repair femoral segmental defect in rats. J Orthop Res (2003) 1.11
Distinct interaction of versican/PG-M with hyaluronan and link protein. J Biol Chem (2003) 1.11
Versican/PG-M regulates chondrogenesis as an extracellular matrix molecule crucial for mesenchymal condensation. J Biol Chem (2005) 1.11
Transient up-regulation of biglycan during skeletal muscle regeneration: delayed fiber growth along with decorin increase in biglycan-deficient mice. Dev Biol (2004) 1.10
Deficiency of biglycan causes cardiac fibroblasts to differentiate into a myofibroblast phenotype. J Biol Chem (2011) 1.10
Ultrasonographic assessment of the ulnar collateral ligament and medial elbow laxity in college baseball players. J Bone Joint Surg Am (2002) 1.09
The mechanical phenotype of biglycan-deficient mice is bone- and gender-specific. Bone (2006) 1.09
Identification and characterization of versican/PG-M aggregates in cartilage. J Biol Chem (2006) 1.09
A novel gene is disrupted at a 14q13 breakpoint of t(2;14) in a patient with mirror-image polydactyly of hands and feet. J Hum Genet (2002) 1.04
The biology of small leucine-rich proteoglycans in bone pathophysiology. J Biol Chem (2012) 1.04
TGF-beta1 and WISP-1/CCN-4 can regulate each other's activity to cooperatively control osteoblast function. J Cell Biochem (2008) 1.03
Regulation of fibrillin-1 by biglycan and decorin is important for tissue preservation in the kidney during pressure-induced injury. Am J Pathol (2004) 1.03
Biglycan is an extracellular MuSK binding protein important for synapse stability. J Neurosci (2012) 1.02
Degradation of raw starch granules by alpha-amylase purified from culture of Aspergillus awamori KT-11. J Biochem Mol Biol (2004) 1.02
Incidence and development of trigger thumb in children. J Hand Surg Am (2006) 0.99
Using sonography for the early detection of elbow injuries among young baseball players. AJR Am J Roentgenol (2006) 0.99
Toll-like receptors and their adaptors are regulated in macrophages after phagocytosis of lipopolysaccharide-coated titanium particles. J Orthop Res (2011) 0.99
Regulation, regulatory activities, and function of biglycan. Crit Rev Eukaryot Gene Expr (2004) 0.98
Variation in mineral properties in normal and mutant bones and teeth. Cells Tissues Organs (2005) 0.98
Identification of genes preferentially expressed in periodontal ligament: specific expression of a novel secreted protein, FDC-SP. Biochem Biophys Res Commun (2005) 0.98
Combinatorial screening of osteoblast response to 3D calcium phosphate/poly(ε-caprolactone) scaffolds using gradients and arrays. Biomaterials (2010) 0.98
Magnetic resonance imaging characteristics of bizarre parosteal osteochondromatous proliferation of the hand: a case report. J Hand Surg Am (2002) 0.97
Classification, treatment, and outcome of osteochondritis dissecans of the humeral capitellum. Surgical technique. J Bone Joint Surg Am (2008) 0.96
Phase I study of TLR9 agonist PF-3512676 in combination with carboplatin and paclitaxel in patients with advanced non-small-cell lung cancer. Cancer Sci (2009) 0.96
Regeneration of bone and periodontal ligament induced by recombinant amelogenin after periodontitis. J Cell Mol Med (2009) 0.96
WISP1/CCN4: a potential target for inhibiting prostate cancer growth and spread to bone. PLoS One (2013) 0.95
Genetic evidence for key roles of decorin and biglycan in dentin mineralization. Matrix Biol (2009) 0.94
A case of osteocartilaginous mass involving the coronoid process of the ulna: solitary osteochondroma or dysplasia epiphysealis hemimelica? J Shoulder Elbow Surg (2003) 0.94
Long-term follow-up of radial shortening osteotomy for Kienbock disease. J Bone Joint Surg Am (2008) 0.94
Biglycan binds to alpha- and gamma-sarcoglycan and regulates their expression during development. J Cell Physiol (2006) 0.94
Retrodental synovial cyst which disappeared after posterior C1-C2 fusion: A case report. J Orthop Surg (Hong Kong) (2000) 0.93
Hyaluronate inhibits the interleukin-1beta-induced expression of matrix metalloproteinase (MMP)-1 and MMP-3 in human synovial cells. Tohoku J Exp Med (2004) 0.93
The proteoglycan biglycan enhances antigen-specific T cell activation potentially via MyD88 and TRIF pathways and triggers autoimmune perimyocarditis. J Immunol (2011) 0.92
Biglycan deficiency increases osteoclast differentiation and activity due to defective osteoblasts. Bone (2005) 0.91
The long-term follow-up of surgical treatment for cervical myelopathy with severe nape and upper arm pain caused by the anomalous vertebral artery: case report. Spine (Phila Pa 1976) (2008) 0.91
Biglycan deficiency interferes with ovariectomy-induced bone loss. J Bone Miner Res (2003) 0.90
The potential functional interaction of biglycan and WISP-1 in controlling differentiation and proliferation of osteogenic cells. Cells Tissues Organs (2008) 0.90
Notch signaling is required for the chondrogenic specification of mouse mesencephalic neural crest cells. Mech Dev (2006) 0.89
Hibernomas show intense accumulation of FDG positron emission tomography. J Comput Assist Tomogr (2006) 0.89
Gene expression profile of human bone marrow stromal cells: high-throughput expressed sequence tag sequencing analysis. Genomics (2002) 0.89
Versican/PG-M is essential for ventricular septal formation subsequent to cardiac atrioventricular cushion development. Glycobiology (2012) 0.89
Fibromodulin-deficient mice reveal dual functions for fibromodulin in regulating dental tissue and alveolar bone formation. Cells Tissues Organs (2008) 0.89
Freeform fabricated scaffolds with roughened struts that enhance both stem cell proliferation and differentiation by controlling cell shape. Biomaterials (2012) 0.89
The short-term reliability of grip strength measurement and the effects of posture and grip span. J Hand Surg Am (2005) 0.88
Upregulation of matrix metalloproteinase (MMP)-1 and its activator MMP-3 of human osteoblast by uniaxial cyclic stimulation. J Biomed Mater Res B Appl Biomater (2007) 0.88
Nanofiber scaffold gradients for interfacial tissue engineering. J Biomater Appl (2012) 0.87
New action pattern of a maltose-forming alpha-amylase from Streptomyces sp. and its possible application in bakery. J Biochem Mol Biol (2002) 0.87
Developmental failure of phalanges in the absence of growth/differentiation factor 5. Bone (2004) 0.85
Characterization of an anti-decorin monoclonal antibody, and its utility. J Biochem (2002) 0.85
Antibiotics-impregnated cement spacers in the first step of two-stage revision for infected totally replaced hip joints: report of ten trial cases. J Orthop Sci (2009) 0.85
Fragment fixation with a bone graft and dynamic staples for osteochondritis dissecans of the humeral capitellum. J Shoulder Elbow Surg (2002) 0.85
Induction of neurogenin-1 expression by sonic hedgehog: Its role in development of trigeminal sensory neurons. Dev Dyn (2003) 0.85
Impaired posterior frontal sutural fusion in the biglycan/decorin double deficient mice. Bone (2006) 0.85
Surgical Repair of Arteriovenous Fistula Associated with Iinfrarenal Aorto-iliac Aneurysm: Report of Two Contrasting Cases. Ann Vasc Dis (2011) 0.85