PubRank

Peter J Crack

Author PubWeight™ 29.32‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradation. Nat Immunol 2006 3.94
2 Reactive oxygen species enhance insulin sensitivity. Cell Metab 2009 2.77
3 Bacterial membrane vesicles deliver peptidoglycan to NOD1 in epithelial cells. Cell Microbiol 2009 1.87
4 Modulation of neuro-inflammation and vascular response by oxidative stress following cerebral ischemia-reperfusion injury. Curr Med Chem 2008 1.31
5 Neuroinflammation and oxidative stress: co-conspirators in the pathology of Parkinson's disease. Neurochem Int 2013 1.15
6 Neural injury following stroke: are Toll-like receptors the link between the immune system and the CNS? Br J Pharmacol 2010 1.12
7 Fibroblasts derived from Gpx1 knockout mice display senescent-like features and are susceptible to H2O2-mediated cell death. Free Radic Biol Med 2004 1.07
8 A mouse model of spinal and bulbar muscular atrophy. Hum Mol Genet 2002 1.06
9 Impact of oxidative stress on neuronal survival. Clin Exp Pharmacol Physiol 2004 1.00
10 An imbalance in antioxidant defense affects cellular function: the pathophysiological consequences of a reduction in antioxidant defense in the glutathione peroxidase-1 (Gpx1) knockout mouse. Redox Rep 2003 0.98
11 Diminished Akt phosphorylation in neurons lacking glutathione peroxidase-1 (Gpx1) leads to increased susceptibility to oxidative stress-induced cell death. J Neurochem 2005 0.93
12 Targeted disruption of SPI3/Serpinb6 does not result in developmental or growth defects, leukocyte dysfunction, or susceptibility to stroke. Mol Cell Biol 2004 0.89
13 Glutathione peroxidase-1 reduces influenza A virus-induced lung inflammation. Am J Respir Cell Mol Biol 2012 0.89
14 A nonfibrin macromolecular cofactor for tPA-mediated plasmin generation following cellular injury. Blood 2009 0.88
15 Glutathione peroxidase-1 protects against cigarette smoke-induced lung inflammation in mice. Am J Physiol Lung Cell Mol Physiol 2010 0.87
16 Glutathione peroxidase 1 and glutathione are required to protect mouse astrocytes from iron-mediated hydrogen peroxide toxicity. J Neurosci Res 2006 0.86
17 Absence of glutathione peroxidase-1 exacerbates cerebral ischemia-reperfusion injury by reducing post-ischemic microvascular perfusion. J Neurochem 2008 0.86
18 Glutathione peroxidase 1 and a high cellular glutathione concentration are essential for effective organic hydroperoxide detoxification in astrocytes. Glia 2006 0.85
19 Levosimendan preserves the contractile responsiveness of hypoxic human myocardium via mitochondrial K(ATP) channel and potential pERK 1/2 activation. Eur J Pharmacol 2011 0.84
20 Glutathione peroxidase-1 primes pro-inflammatory cytokine production after LPS challenge in vivo. PLoS One 2012 0.84
21 Mice lacking glutathione peroxidase-1 activity show increased TUNEL staining and an accelerated inflammatory response in brain following a cold-induced injury. Exp Neurol 2002 0.83
22 Akt phosphorylation and NFkappaB activation are counterregulated under conditions of oxidative stress. Exp Cell Res 2004 0.82
23 MyD88 is a critical regulator of hematopoietic cell-mediated neuroprotection seen after stroke. PLoS One 2013 0.82
24 A global transcriptomic view of the multifaceted role of glutathione peroxidase-1 in cerebral ischemic-reperfusion injury. Free Radic Biol Med 2010 0.81
25 Insulin-regulated aminopeptidase deficiency provides protection against ischemic stroke in mice. J Neurotrauma 2011 0.79
26 Weight-bearing locomotion in the developing opossum, Monodelphis domestica following spinal transection: remodeling of neuronal circuits caudal to lesion. PLoS One 2013 0.78
27 Synthesis of a hypoxia-targeted conjugate of the cardioprotective agent 3',4'-dihydroxyflavonol and evaluation of its ability to reduce ischaemia/reperfusion injury. Bioorg Med Chem Lett 2011 0.75
28 Divergent roles of glutathione peroxidase-1 (Gpx1) in regulation of leukocyte-endothelial cell interactions in the inflamed cerebral microvasculature. Microcirculation 2011 0.75