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1
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The PARP side of the nucleus: molecular actions, physiological outcomes, and clinical targets.
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Mol Cell
|
2010
|
5.06
|
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2
|
Poly(ADP-ribosyl)ation by PARP-1: 'PAR-laying' NAD+ into a nuclear signal.
|
Genes Dev
|
2005
|
4.61
|
|
3
|
A rapid, extensive, and transient transcriptional response to estrogen signaling in breast cancer cells.
|
Cell
|
2011
|
4.42
|
|
4
|
NAD+-dependent modulation of chromatin structure and transcription by nucleosome binding properties of PARP-1.
|
Cell
|
2004
|
4.21
|
|
5
|
New insights into the molecular and cellular functions of poly(ADP-ribose) and PARPs.
|
Nat Rev Mol Cell Biol
|
2012
|
3.45
|
|
6
|
Reciprocal binding of PARP-1 and histone H1 at promoters specifies transcriptional outcomes.
|
Science
|
2008
|
3.45
|
|
7
|
Enhancer transcripts mark active estrogen receptor binding sites.
|
Genome Res
|
2013
|
2.82
|
|
8
|
On PAR with PARP: cellular stress signaling through poly(ADP-ribose) and PARP-1.
|
Genes Dev
|
2012
|
2.82
|
|
9
|
Regulation of coactivator complex assembly and function by protein arginine methylation and demethylimination.
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Proc Natl Acad Sci U S A
|
2005
|
2.40
|
|
10
|
Genomic analyses of transcription factor binding, histone acetylation, and gene expression reveal mechanistically distinct classes of estrogen-regulated promoters.
|
Mol Cell Biol
|
2007
|
2.33
|
|
11
|
Signaling pathways differentially affect RNA polymerase II initiation, pausing, and elongation rate in cells.
|
Mol Cell
|
2013
|
2.13
|
|
12
|
PARP-1 regulates chromatin structure and transcription through a KDM5B-dependent pathway.
|
Mol Cell
|
2010
|
2.06
|
|
13
|
Specific contributions of histone tails and their acetylation to the mechanical stability of nucleosomes.
|
J Mol Biol
|
2004
|
1.87
|
|
14
|
The histone variant macroH2A1 marks repressed autosomal chromatin, but protects a subset of its target genes from silencing.
|
Genes Dev
|
2009
|
1.82
|
|
15
|
The DNA binding and catalytic domains of poly(ADP-ribose) polymerase 1 cooperate in the regulation of chromatin structure and transcription.
|
Mol Cell Biol
|
2007
|
1.82
|
|
16
|
Genome-wide analysis of estrogen receptor alpha DNA binding and tethering mechanisms identifies Runx1 as a novel tethering factor in receptor-mediated transcriptional activation.
|
Mol Cell Biol
|
2010
|
1.75
|
|
17
|
Acetylation of estrogen receptor alpha by p300 at lysines 266 and 268 enhances the deoxyribonucleic acid binding and transactivation activities of the receptor.
|
Mol Endocrinol
|
2006
|
1.73
|
|
18
|
Enzymes in the NAD+ salvage pathway regulate SIRT1 activity at target gene promoters.
|
J Biol Chem
|
2009
|
1.70
|
|
19
|
A global view of transcriptional regulation by nuclear receptors: gene expression, factor localization, and DNA sequence analysis.
|
Nucl Recept Signal
|
2008
|
1.62
|
|
20
|
Postrecruitment regulation of RNA polymerase II directs rapid signaling responses at the promoters of estrogen target genes.
|
Mol Cell Biol
|
2008
|
1.60
|
|
21
|
Estrogen-regulated gene networks in human breast cancer cells: involvement of E2F1 in the regulation of cell proliferation.
|
Mol Endocrinol
|
2007
|
1.55
|
|
22
|
Poly(ADP-ribose) polymerase 1 is inhibited by a histone H2A variant, MacroH2A, and contributes to silencing of the inactive X chromosome.
|
J Biol Chem
|
2007
|
1.53
|
|
23
|
The Zn3 domain of human poly(ADP-ribose) polymerase-1 (PARP-1) functions in both DNA-dependent poly(ADP-ribose) synthesis activity and chromatin compaction.
|
J Biol Chem
|
2010
|
1.47
|
|
24
|
SIRT1-dependent regulation of chromatin and transcription: linking NAD(+) metabolism and signaling to the control of cellular functions.
|
Biochim Biophys Acta
|
2009
|
1.41
|
|
25
|
Genomic analyses of hormone signaling and gene regulation.
|
Annu Rev Physiol
|
2010
|
1.38
|
|
26
|
Genome-wide analysis reveals PADI4 cooperates with Elk-1 to activate c-Fos expression in breast cancer cells.
|
PLoS Genet
|
2011
|
1.33
|
|
27
|
Global analysis of transcriptional regulation by poly(ADP-ribose) polymerase-1 and poly(ADP-ribose) glycohydrolase in MCF-7 human breast cancer cells.
|
J Biol Chem
|
2009
|
1.32
|
|
28
|
Smads orchestrate specific histone modifications and chromatin remodeling to activate transcription.
|
EMBO J
|
2006
|
1.30
|
|
29
|
Multiple facets of the unique histone variant macroH2A: from genomics to cell biology.
|
Cell Cycle
|
2010
|
1.25
|
|
30
|
Clickable NAD analogues for labeling substrate proteins of poly(ADP-ribose) polymerases.
|
J Am Chem Soc
|
2010
|
1.18
|
|
31
|
p300-mediated tax transactivation from recombinant chromatin: histone tail deletion mimics coactivator function.
|
Mol Cell Biol
|
2002
|
1.12
|
|
32
|
New functions for an ancient domain.
|
Nat Struct Mol Biol
|
2009
|
1.12
|
|
33
|
Mediator and p300/CBP-steroid receptor coactivator complexes have distinct roles, but function synergistically, during estrogen receptor alpha-dependent transcription with chromatin templates.
|
Mol Cell Biol
|
2003
|
1.12
|
|
34
|
Transcriptional activation by nuclear receptors.
|
Essays Biochem
|
2004
|
1.10
|
|
35
|
Selective recognition of distinct classes of coactivators by a ligand-inducible activation domain.
|
Mol Cell
|
2004
|
1.08
|
|
36
|
Histone H1 represses estrogen receptor alpha transcriptional activity by selectively inhibiting receptor-mediated transcription initiation.
|
Mol Cell Biol
|
2002
|
1.06
|
|
37
|
Altered pharmacology and distinct coactivator usage for estrogen receptor-dependent transcription through activating protein-1.
|
Proc Natl Acad Sci U S A
|
2005
|
1.05
|
|
38
|
Chromatin exposes intrinsic differences in the transcriptional activities of estrogen receptors alpha and beta.
|
EMBO J
|
2003
|
1.04
|
|
39
|
Isoflavones stimulate estrogen receptor-mediated core histone acetylation.
|
Biochem Biophys Res Commun
|
2004
|
1.03
|
|
40
|
Hormone-regulated transcriptomes: lessons learned from estrogen signaling pathways in breast cancer cells.
|
Mol Cell Endocrinol
|
2013
|
0.99
|
|
41
|
MYBBP1a is a novel repressor of NF-kappaB.
|
J Mol Biol
|
2006
|
0.99
|
|
42
|
The role of the C-terminal extension (CTE) of the estrogen receptor alpha and beta DNA binding domain in DNA binding and interaction with HMGB.
|
J Biol Chem
|
2004
|
0.99
|
|
43
|
From discovery to function: the expanding roles of long noncoding RNAs in physiology and disease.
|
Endocr Rev
|
2014
|
0.98
|
|
44
|
PARP inhibitors and the treatment of breast cancer: beyond BRCA1/2?
|
Breast Cancer Res
|
2009
|
0.95
|
|
45
|
Multiple sequence-specific DNA-binding proteins mediate estrogen receptor signaling through a tethering pathway.
|
Mol Endocrinol
|
2011
|
0.95
|
|
46
|
A role for BAF57 in cell cycle-dependent transcriptional regulation by the SWI/SNF chromatin remodeling complex.
|
Cancer Res
|
2010
|
0.95
|
|
47
|
Regulation of chromatin structure and chromatin-dependent transcription by poly(ADP-ribose) polymerase-1: possible targets for drug-based therapies.
|
Subcell Biochem
|
2007
|
0.94
|
|
48
|
Regulation of poly(ADP-ribose) polymerase-1-dependent gene expression through promoter-directed recruitment of a nuclear NAD+ synthase.
|
J Biol Chem
|
2012
|
0.93
|
|
49
|
A novel Arabidopsis acetyltransferase interacts with the geminivirus movement protein NSP.
|
Plant Cell
|
2003
|
0.92
|
|
50
|
Promoter cleavage: a topoIIbeta and PARP-1 collaboration.
|
Cell
|
2006
|
0.89
|
|
51
|
Small molecules, big effects: a role for chromatin-localized metabolite biosynthesis in gene regulation.
|
Mol Cell
|
2011
|
0.89
|
|
52
|
Transcriptional activation by thyroid hormone receptor-beta involves chromatin remodeling, histone acetylation, and synergistic stimulation by p300 and steroid receptor coactivators.
|
Mol Endocrinol
|
2003
|
0.87
|
|
53
|
Biochemical analyses of nuclear receptor-dependent transcription with chromatin templates.
|
Prog Mol Biol Transl Sci
|
2009
|
0.86
|
|
54
|
A one and a two … expanding roles for poly(ADP-ribose) polymerases in metabolism.
|
Cell Metab
|
2011
|
0.85
|
|
55
|
Evolution of ligand specificity in vertebrate corticosteroid receptors.
|
BMC Evol Biol
|
2011
|
0.84
|
|
56
|
Minireview: Long noncoding RNAs: new "links" between gene expression and cellular outcomes in endocrinology.
|
Mol Endocrinol
|
2013
|
0.83
|
|
57
|
Development of a stable dual cell-line GFP expression system to study estrogenic endocrine disruptors.
|
Biotechnol Bioeng
|
2008
|
0.82
|
|
58
|
Visualizing the histone code on LSD1.
|
Cell
|
2007
|
0.81
|
|
59
|
Mapping ERβ genomic binding sites reveals unique genomic features and identifies EBF1 as an ERβ interactor.
|
PLoS One
|
2013
|
0.80
|
|
60
|
Estrogen regulates JNK1 genomic localization to control gene expression and cell growth in breast cancer cells.
|
Mol Endocrinol
|
2012
|
0.80
|
|
61
|
From Discovery to Function: The Expanding Roles of Long Non-Coding RNAs in Physiology and Disease.
|
Endocr Rev
|
2015
|
0.78
|
|
62
|
Activation of estrogen receptor α by raloxifene through an activating protein-1-dependent tethering mechanism in human cervical epithelial cancer cells: a role for c-Jun N-terminal kinase.
|
Mol Cell Endocrinol
|
2011
|
0.77
|
|
63
|
A PreSTIGEous use of LncRNAs to predict enhancers.
|
Cell Cycle
|
2015
|
0.75
|
|
64
|
Editorial: Centennial Celebration - A Focus on Endocrine Disrupting Chemicals… One Hundred Years in the Making.
|
Mol Endocrinol
|
2016
|
0.75
|
|
65
|
Generation and Characterization of Recombinant Antibody-Like ADP-Ribose Binding Proteins.
|
Biochemistry
|
2017
|
0.75
|