Annemieke Verstuyf

Author PubWeight™ 54.72‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Vitamin D and human health: lessons from vitamin D receptor null mice. Endocr Rev 2008 5.28
2 Vitamin D and cancer. J Steroid Biochem Mol Biol 2006 1.72
3 The E2F-regulated gene Chk1 is highly expressed in triple-negative estrogen receptor /progesterone receptor /HER-2 breast carcinomas. Cancer Res 2007 1.48
4 Analogs of 1alpha,25-dihydroxyvitamin D3 as pluripotent immunomodulators. J Cell Biochem 2003 1.31
5 The vitamin D receptor gene FokI polymorphism: functional impact on the immune system. Eur J Immunol 2007 1.28
6 Human T lymphocytes are direct targets of 1,25-dihydroxyvitamin D3 in the immune system. J Steroid Biochem Mol Biol 2010 1.18
7 The vitamin D analog, TX527, promotes a human CD4+CD25highCD127low regulatory T cell profile and induces a migratory signature specific for homing to sites of inflammation. J Immunol 2010 1.12
8 Vitamin D status at breast cancer diagnosis: correlation with tumor characteristics, disease outcome, and genetic determinants of vitamin D insufficiency. Carcinogenesis 2012 1.12
9 Derivatives of vitamins D2 and D3 activate three MAPK pathways and upregulate pRb expression in differentiating HL60 cells. Cell Cycle 2003 1.08
10 Differential sensitivity of epidermal cell subpopulations to beta-catenin-induced ectopic hair follicle formation. Dev Biol 2010 1.06
11 Antineoplastic effects of 1,25(OH)2D3 and its analogs in breast, prostate and colorectal cancer. Endocr Relat Cancer 2013 1.06
12 1,25-Dihydroxyvitamin D3 and analogues protect primary human keratinocytes against UVB-induced DNA damage. J Photochem Photobiol B 2005 1.00
13 1,25-dihydroxyvitamin D3 influences cellular homocysteine levels in murine preosteoblastic MC3T3-E1 cells by direct regulation of cystathionine β-synthase. J Bone Miner Res 2011 0.97
14 1,25-Dihydroxyvitamin D3 alters murine dendritic cell behaviour in vitro and in vivo. Diabetes Metab Res Rev 2011 0.96
15 1,25-Dihydroxyvitamin D3 promotes tolerogenic dendritic cells with functional migratory properties in NOD mice. J Immunol 2014 0.95
16 The Vitamin D analogue TX 527 blocks NF-kappaB activation in peripheral blood mononuclear cells of patients with Crohn's disease. J Steroid Biochem Mol Biol 2006 0.95
17 Immune regulation of 25-hydroxyvitamin D-1alpha-hydroxylase in human monocytic THP1 cells: mechanisms of interferon-gamma-mediated induction. J Clin Endocrinol Metab 2006 0.94
18 The effects of 1alpha,25-dihydroxyvitamin D3 on the expression of DNA replication genes. J Bone Miner Res 2004 0.94
19 Unaltered diabetes presentation in NOD mice lacking the vitamin D receptor. Diabetes 2007 0.94
20 Extraskeletal effects of vitamin D. Endocrinol Metab Clin North Am 2012 0.93
21 Novel insights in the immune function of the vitamin D system: synergism with interferon-beta. J Steroid Biochem Mol Biol 2006 0.91
22 Superagonistic action of 14-epi-analogs of 1,25-dihydroxyvitamin D explained by vitamin D receptor-coactivator interaction. Mol Pharmacol 2005 0.91
23 Two 14-epi analogues of 1,25-dihydroxyvitamin D3 protect human keratinocytes against the effects of UVB. Arch Dermatol Res 2004 0.90
24 1,25-dihydroxyvitamin D3 and a superagonistic analog in combination with paclitaxel or suberoylanilide hydroxamic acid have potent antiproliferative effects on anaplastic thyroid cancer. J Steroid Biochem Mol Biol 2010 0.86
25 Characterization of the condensin component Cnap1 and protein kinase Melk as novel E2F target genes down-regulated by 1,25-dihydroxyvitamin D3. J Biol Chem 2005 0.86
26 The impact of 1,25(OH)2D3 and its structural analogs on gene expression in cancer cells--a microarray approach. Anticancer Res 2009 0.86
27 Altered expression of key players in vitamin D metabolism and signaling in malignant and benign thyroid tumors. J Histochem Cytochem 2012 0.85
28 Proteome analysis demonstrates profound alterations in human dendritic cell nature by TX527, an analogue of vitamin D. Proteomics 2009 0.85
29 Superagonistic fluorinated vitamin D3 analogs stabilize helix 12 of the vitamin D receptor. Chem Biol 2008 0.84
30 1 Alpha,25-dihydroxyvitamin D3 and its TX527 analog inhibit the growth of endothelial cells transformed by Kaposi sarcoma-associated herpes virus G protein-coupled receptor in vitro and in vivo. Endocrinology 2009 0.84
31 Mechanisms for the selective action of Vitamin D analogs. J Steroid Biochem Mol Biol 2005 0.84
32 The vitamin D analog TX527 ameliorates disease symptoms in a chemically induced model of inflammatory bowel disease. J Steroid Biochem Mol Biol 2012 0.83
33 1α,25-Dihydroxyvitamin D3 and its analogs as modulators of human dendritic cells: a comparison dose-titration study. J Steroid Biochem Mol Biol 2012 0.82
34 Vitamin D analogs and coactivators. Anticancer Res 2006 0.80
35 1alpha,25-Dihydroxyvitamin D3-induced down-regulation of the checkpoint proteins, Chk1 and Claspin, is mediated by the pocket proteins p107 and p130. J Steroid Biochem Mol Biol 2006 0.80
36 Straight from D-Heart: vitamin D status and cardiovascular disease. Curr Opin Lipidol 2012 0.80
37 Calcium and vitamin d supplementation in men. J Osteoporos 2011 0.79
38 Vitamin D resistance. Best Pract Res Clin Endocrinol Metab 2006 0.79
39 Vitamin D in thyroid tumorigenesis and development. Prog Histochem Cytochem 2013 0.79
40 Microarray analysis of 1alpha,25-dihydroxyvitamin D3-treated MC3T3-E1 cells. J Steroid Biochem Mol Biol 2004 0.79
41 The effect of orthology and coregulation on detecting regulatory motifs. PLoS One 2010 0.78
42 ModuleDigger: an itemset mining framework for the detection of cis-regulatory modules. BMC Bioinformatics 2009 0.78
43 Nrp2 deficiency leads to trabecular bone loss and is accompanied by enhanced osteoclast and reduced osteoblast numbers. Bone 2013 0.78
44 NFκB pathway is down-regulated by 1α,25(OH)(2)-vitamin D(3) in endothelial cells transformed by Kaposi sarcoma-associated herpes virus G protein coupled receptor. Steroids 2012 0.78
45 1,25-Dihydroxyvitamin D3 and the aging-related forkhead box O and sestrin proteins in osteoblasts. J Steroid Biochem Mol Biol 2012 0.78
46 Vitamin D, mitochondria, and muscle. J Clin Endocrinol Metab 2013 0.77
47 CD-ring modified vitamin D3 analogs and their superagonistic action. J Steroid Biochem Mol Biol 2010 0.77
48 Prospects for vitamin D receptor modulators as candidate drugs for cancer and (auto)immune diseases. Recent Results Cancer Res 2003 0.77
49 Vitamin D(3): synthesis of seco C-9,11,21-trisnor-17-methyl-1 alpha, 25-dihydroxyvitamin D(3) analogues. Bioorg Med Chem Lett 2002 0.77
50 Vitamin D action: lessons from VDR and Cyp27b1 null mice. Pediatr Endocrinol Rev 2013 0.77
51 Antiproliferative and calcemic actions of trans-decalin CD-ring analogs of 1,25-dihydroxyvitamin D3. Anticancer Res 2009 0.76
52 The odd-skipped related genes Osr1 and Osr2 are induced by 1,25-dihydroxyvitamin D3. J Steroid Biochem Mol Biol 2012 0.76
53 Synthesis, structure, and biological activity of des-side chain analogues of 1α,25-dihydroxyvitamin D3 with substituents at C18. ChemMedChem 2011 0.76
54 Identification and characterization of MEL-3, a novel AR antagonist that suppresses prostate cancer cell growth. Mol Cancer Ther 2012 0.76
55 Microarray analysis of MCF-7 breast cancer cells treated with 1,25-dihydroxyvitamin D3 or a 17-methyl-D-ring analog. Anticancer Res 2009 0.75
56 Altered Vitamin D receptor-coactivator interactions reflect superagonism of Vitamin D analogs. J Steroid Biochem Mol Biol 2005 0.75
57 Synthesis, conformational analysis, and biological evaluation of 19-nor-vitamin D3 analogues with A-ring modifications. J Med Chem 2009 0.75
58 Synthesis and biological activity of 22-oxa CD-ring modified analogues of 1alpha,25-dihydroxyvitamin D3: cis-perhydrindane CE-ring analogues. Bioorg Med Chem Lett 2004 0.75
59 Novel A-ring homodimeric C-3-carbamate analogues of 1alpha,25-dihydroxyvitamin D3: synthesis and preliminary biological evaluation. Bioorg Med Chem 2006 0.75
60 Synthesis and biological activity of 22-oxa CD-ring modified analogues of 1alpha,25-dihydroxyvitamin D3: spiro[5.5]undecane CF-ring analogues. Bioorg Med Chem Lett 2004 0.75
61 Versatile synthesis and biological evaluation of 1,3-diamino-substituted 1alpha,25-dihydroxyvitamin D3 analogues. Bioorg Med Chem 2005 0.75
62 Removal of C-ring from the CD-ring skeleton of 1alpha,25-dihydroxyvitamin D3 does not alter its target tissue metabolism significantly. Arch Biochem Biophys 2006 0.75
63 Biological activity and conformational analysis of C20 and C14 epimers of CD-ring modified trans-decalin 1alpha,25-dihydroxyvitamin D analogs. J Steroid Biochem Mol Biol 2004 0.75
64 Synthesis of 1alpha,25-dihydroxyvitamin D analogues featuring a S(2)-symmetric CD-ring core. Molecules 2009 0.75
65 Synthesis of spiro[4.5]decane CF-ring analogues of 1 alpha,25-dihydroxyvitamin D3. Org Lett 2006 0.75
66 Synthesis, biological activity, and conformational analysis of CD-ring modified trans-decalin 1 alpha,25-dihydroxyvitamin D analogs. Org Biomol Chem 2003 0.75
67 The development of CD-ring modified analogs of 1alpha,25-dihydroxyvitamin D. J Steroid Biochem Mol Biol 2007 0.75
68 Chemoenzymatic synthesis and biological evaluation of C-3 carbamate analogues of 1alpha,25-dihydroxyvitamin D3. Bioorg Med Chem 2004 0.75
69 Synthesis and biological evaluation of new 6-s-cis locked 1,2,25-trihydroxyprevitamin D3 analogues. Bioorg Med Chem 2007 0.75
70 Synthesis and biological activity of previtamin D(3) analogues with A-ring modifications. Bioorg Med Chem 2008 0.75
71 Vitamin D(3): synthesis of seco-C-9,11-bisnor-17-methyl-1 alpha,25-dihydroxyvitamin D(3) analogues. Bioorg Med Chem Lett 2002 0.75
72 Previtamin D3 with a trans-fused decalin CD-ring has pronounced genomic activity. J Biol Chem 2003 0.75