1
|
Vitamin D and human health: lessons from vitamin D receptor null mice.
|
Endocr Rev
|
2008
|
5.28
|
2
|
Vitamin D and cancer.
|
J Steroid Biochem Mol Biol
|
2006
|
1.72
|
3
|
The E2F-regulated gene Chk1 is highly expressed in triple-negative estrogen receptor /progesterone receptor /HER-2 breast carcinomas.
|
Cancer Res
|
2007
|
1.48
|
4
|
Analogs of 1alpha,25-dihydroxyvitamin D3 as pluripotent immunomodulators.
|
J Cell Biochem
|
2003
|
1.31
|
5
|
The vitamin D receptor gene FokI polymorphism: functional impact on the immune system.
|
Eur J Immunol
|
2007
|
1.28
|
6
|
Human T lymphocytes are direct targets of 1,25-dihydroxyvitamin D3 in the immune system.
|
J Steroid Biochem Mol Biol
|
2010
|
1.18
|
7
|
The vitamin D analog, TX527, promotes a human CD4+CD25highCD127low regulatory T cell profile and induces a migratory signature specific for homing to sites of inflammation.
|
J Immunol
|
2010
|
1.12
|
8
|
Vitamin D status at breast cancer diagnosis: correlation with tumor characteristics, disease outcome, and genetic determinants of vitamin D insufficiency.
|
Carcinogenesis
|
2012
|
1.12
|
9
|
Derivatives of vitamins D2 and D3 activate three MAPK pathways and upregulate pRb expression in differentiating HL60 cells.
|
Cell Cycle
|
2003
|
1.08
|
10
|
Differential sensitivity of epidermal cell subpopulations to beta-catenin-induced ectopic hair follicle formation.
|
Dev Biol
|
2010
|
1.06
|
11
|
Antineoplastic effects of 1,25(OH)2D3 and its analogs in breast, prostate and colorectal cancer.
|
Endocr Relat Cancer
|
2013
|
1.06
|
12
|
1,25-Dihydroxyvitamin D3 and analogues protect primary human keratinocytes against UVB-induced DNA damage.
|
J Photochem Photobiol B
|
2005
|
1.00
|
13
|
1,25-dihydroxyvitamin D3 influences cellular homocysteine levels in murine preosteoblastic MC3T3-E1 cells by direct regulation of cystathionine β-synthase.
|
J Bone Miner Res
|
2011
|
0.97
|
14
|
1,25-Dihydroxyvitamin D3 alters murine dendritic cell behaviour in vitro and in vivo.
|
Diabetes Metab Res Rev
|
2011
|
0.96
|
15
|
1,25-Dihydroxyvitamin D3 promotes tolerogenic dendritic cells with functional migratory properties in NOD mice.
|
J Immunol
|
2014
|
0.95
|
16
|
The Vitamin D analogue TX 527 blocks NF-kappaB activation in peripheral blood mononuclear cells of patients with Crohn's disease.
|
J Steroid Biochem Mol Biol
|
2006
|
0.95
|
17
|
Immune regulation of 25-hydroxyvitamin D-1alpha-hydroxylase in human monocytic THP1 cells: mechanisms of interferon-gamma-mediated induction.
|
J Clin Endocrinol Metab
|
2006
|
0.94
|
18
|
The effects of 1alpha,25-dihydroxyvitamin D3 on the expression of DNA replication genes.
|
J Bone Miner Res
|
2004
|
0.94
|
19
|
Unaltered diabetes presentation in NOD mice lacking the vitamin D receptor.
|
Diabetes
|
2007
|
0.94
|
20
|
Extraskeletal effects of vitamin D.
|
Endocrinol Metab Clin North Am
|
2012
|
0.93
|
21
|
Novel insights in the immune function of the vitamin D system: synergism with interferon-beta.
|
J Steroid Biochem Mol Biol
|
2006
|
0.91
|
22
|
Superagonistic action of 14-epi-analogs of 1,25-dihydroxyvitamin D explained by vitamin D receptor-coactivator interaction.
|
Mol Pharmacol
|
2005
|
0.91
|
23
|
Two 14-epi analogues of 1,25-dihydroxyvitamin D3 protect human keratinocytes against the effects of UVB.
|
Arch Dermatol Res
|
2004
|
0.90
|
24
|
1,25-dihydroxyvitamin D3 and a superagonistic analog in combination with paclitaxel or suberoylanilide hydroxamic acid have potent antiproliferative effects on anaplastic thyroid cancer.
|
J Steroid Biochem Mol Biol
|
2010
|
0.86
|
25
|
Characterization of the condensin component Cnap1 and protein kinase Melk as novel E2F target genes down-regulated by 1,25-dihydroxyvitamin D3.
|
J Biol Chem
|
2005
|
0.86
|
26
|
The impact of 1,25(OH)2D3 and its structural analogs on gene expression in cancer cells--a microarray approach.
|
Anticancer Res
|
2009
|
0.86
|
27
|
Altered expression of key players in vitamin D metabolism and signaling in malignant and benign thyroid tumors.
|
J Histochem Cytochem
|
2012
|
0.85
|
28
|
Proteome analysis demonstrates profound alterations in human dendritic cell nature by TX527, an analogue of vitamin D.
|
Proteomics
|
2009
|
0.85
|
29
|
Superagonistic fluorinated vitamin D3 analogs stabilize helix 12 of the vitamin D receptor.
|
Chem Biol
|
2008
|
0.84
|
30
|
1 Alpha,25-dihydroxyvitamin D3 and its TX527 analog inhibit the growth of endothelial cells transformed by Kaposi sarcoma-associated herpes virus G protein-coupled receptor in vitro and in vivo.
|
Endocrinology
|
2009
|
0.84
|
31
|
Mechanisms for the selective action of Vitamin D analogs.
|
J Steroid Biochem Mol Biol
|
2005
|
0.84
|
32
|
The vitamin D analog TX527 ameliorates disease symptoms in a chemically induced model of inflammatory bowel disease.
|
J Steroid Biochem Mol Biol
|
2012
|
0.83
|
33
|
1α,25-Dihydroxyvitamin D3 and its analogs as modulators of human dendritic cells: a comparison dose-titration study.
|
J Steroid Biochem Mol Biol
|
2012
|
0.82
|
34
|
Vitamin D analogs and coactivators.
|
Anticancer Res
|
2006
|
0.80
|
35
|
1alpha,25-Dihydroxyvitamin D3-induced down-regulation of the checkpoint proteins, Chk1 and Claspin, is mediated by the pocket proteins p107 and p130.
|
J Steroid Biochem Mol Biol
|
2006
|
0.80
|
36
|
Straight from D-Heart: vitamin D status and cardiovascular disease.
|
Curr Opin Lipidol
|
2012
|
0.80
|
37
|
Calcium and vitamin d supplementation in men.
|
J Osteoporos
|
2011
|
0.79
|
38
|
Vitamin D resistance.
|
Best Pract Res Clin Endocrinol Metab
|
2006
|
0.79
|
39
|
Vitamin D in thyroid tumorigenesis and development.
|
Prog Histochem Cytochem
|
2013
|
0.79
|
40
|
Microarray analysis of 1alpha,25-dihydroxyvitamin D3-treated MC3T3-E1 cells.
|
J Steroid Biochem Mol Biol
|
2004
|
0.79
|
41
|
The effect of orthology and coregulation on detecting regulatory motifs.
|
PLoS One
|
2010
|
0.78
|
42
|
ModuleDigger: an itemset mining framework for the detection of cis-regulatory modules.
|
BMC Bioinformatics
|
2009
|
0.78
|
43
|
Nrp2 deficiency leads to trabecular bone loss and is accompanied by enhanced osteoclast and reduced osteoblast numbers.
|
Bone
|
2013
|
0.78
|
44
|
NFκB pathway is down-regulated by 1α,25(OH)(2)-vitamin D(3) in endothelial cells transformed by Kaposi sarcoma-associated herpes virus G protein coupled receptor.
|
Steroids
|
2012
|
0.78
|
45
|
1,25-Dihydroxyvitamin D3 and the aging-related forkhead box O and sestrin proteins in osteoblasts.
|
J Steroid Biochem Mol Biol
|
2012
|
0.78
|
46
|
Vitamin D, mitochondria, and muscle.
|
J Clin Endocrinol Metab
|
2013
|
0.77
|
47
|
CD-ring modified vitamin D3 analogs and their superagonistic action.
|
J Steroid Biochem Mol Biol
|
2010
|
0.77
|
48
|
Prospects for vitamin D receptor modulators as candidate drugs for cancer and (auto)immune diseases.
|
Recent Results Cancer Res
|
2003
|
0.77
|
49
|
Vitamin D(3): synthesis of seco C-9,11,21-trisnor-17-methyl-1 alpha, 25-dihydroxyvitamin D(3) analogues.
|
Bioorg Med Chem Lett
|
2002
|
0.77
|
50
|
Vitamin D action: lessons from VDR and Cyp27b1 null mice.
|
Pediatr Endocrinol Rev
|
2013
|
0.77
|
51
|
Antiproliferative and calcemic actions of trans-decalin CD-ring analogs of 1,25-dihydroxyvitamin D3.
|
Anticancer Res
|
2009
|
0.76
|
52
|
The odd-skipped related genes Osr1 and Osr2 are induced by 1,25-dihydroxyvitamin D3.
|
J Steroid Biochem Mol Biol
|
2012
|
0.76
|
53
|
Synthesis, structure, and biological activity of des-side chain analogues of 1α,25-dihydroxyvitamin D3 with substituents at C18.
|
ChemMedChem
|
2011
|
0.76
|
54
|
Identification and characterization of MEL-3, a novel AR antagonist that suppresses prostate cancer cell growth.
|
Mol Cancer Ther
|
2012
|
0.76
|
55
|
Microarray analysis of MCF-7 breast cancer cells treated with 1,25-dihydroxyvitamin D3 or a 17-methyl-D-ring analog.
|
Anticancer Res
|
2009
|
0.75
|
56
|
Altered Vitamin D receptor-coactivator interactions reflect superagonism of Vitamin D analogs.
|
J Steroid Biochem Mol Biol
|
2005
|
0.75
|
57
|
Synthesis, conformational analysis, and biological evaluation of 19-nor-vitamin D3 analogues with A-ring modifications.
|
J Med Chem
|
2009
|
0.75
|
58
|
Synthesis and biological activity of 22-oxa CD-ring modified analogues of 1alpha,25-dihydroxyvitamin D3: cis-perhydrindane CE-ring analogues.
|
Bioorg Med Chem Lett
|
2004
|
0.75
|
59
|
Novel A-ring homodimeric C-3-carbamate analogues of 1alpha,25-dihydroxyvitamin D3: synthesis and preliminary biological evaluation.
|
Bioorg Med Chem
|
2006
|
0.75
|
60
|
Synthesis and biological activity of 22-oxa CD-ring modified analogues of 1alpha,25-dihydroxyvitamin D3: spiro[5.5]undecane CF-ring analogues.
|
Bioorg Med Chem Lett
|
2004
|
0.75
|
61
|
Versatile synthesis and biological evaluation of 1,3-diamino-substituted 1alpha,25-dihydroxyvitamin D3 analogues.
|
Bioorg Med Chem
|
2005
|
0.75
|
62
|
Removal of C-ring from the CD-ring skeleton of 1alpha,25-dihydroxyvitamin D3 does not alter its target tissue metabolism significantly.
|
Arch Biochem Biophys
|
2006
|
0.75
|
63
|
Biological activity and conformational analysis of C20 and C14 epimers of CD-ring modified trans-decalin 1alpha,25-dihydroxyvitamin D analogs.
|
J Steroid Biochem Mol Biol
|
2004
|
0.75
|
64
|
Synthesis of 1alpha,25-dihydroxyvitamin D analogues featuring a S(2)-symmetric CD-ring core.
|
Molecules
|
2009
|
0.75
|
65
|
Synthesis of spiro[4.5]decane CF-ring analogues of 1 alpha,25-dihydroxyvitamin D3.
|
Org Lett
|
2006
|
0.75
|
66
|
Synthesis, biological activity, and conformational analysis of CD-ring modified trans-decalin 1 alpha,25-dihydroxyvitamin D analogs.
|
Org Biomol Chem
|
2003
|
0.75
|
67
|
The development of CD-ring modified analogs of 1alpha,25-dihydroxyvitamin D.
|
J Steroid Biochem Mol Biol
|
2007
|
0.75
|
68
|
Chemoenzymatic synthesis and biological evaluation of C-3 carbamate analogues of 1alpha,25-dihydroxyvitamin D3.
|
Bioorg Med Chem
|
2004
|
0.75
|
69
|
Synthesis and biological evaluation of new 6-s-cis locked 1,2,25-trihydroxyprevitamin D3 analogues.
|
Bioorg Med Chem
|
2007
|
0.75
|
70
|
Synthesis and biological activity of previtamin D(3) analogues with A-ring modifications.
|
Bioorg Med Chem
|
2008
|
0.75
|
71
|
Vitamin D(3): synthesis of seco-C-9,11-bisnor-17-methyl-1 alpha,25-dihydroxyvitamin D(3) analogues.
|
Bioorg Med Chem Lett
|
2002
|
0.75
|
72
|
Previtamin D3 with a trans-fused decalin CD-ring has pronounced genomic activity.
|
J Biol Chem
|
2003
|
0.75
|