Published in J Biol Chem on September 06, 2005
Vitamin D and human health: lessons from vitamin D receptor null mice. Endocr Rev (2008) 5.28
Retracted Maternal embryonic leucine zipper kinase (MELK) reduces replication stress in glioblastoma cells. J Biol Chem (2013) 1.04
1,25-dihydroxyvitamin D3 influences cellular homocysteine levels in murine preosteoblastic MC3T3-E1 cells by direct regulation of cystathionine β-synthase. J Bone Miner Res (2011) 0.97
The CHR site: definition and genome-wide identification of a cell cycle transcriptional element. Nucleic Acids Res (2014) 0.93
Distinct pigmentary and melanocortin 1 receptor-dependent components of cutaneous defense against ultraviolet radiation. PLoS Genet (2006) 0.90
MELK-T1, a small-molecule inhibitor of protein kinase MELK, decreases DNA-damage tolerance in proliferating cancer cells. Biosci Rep (2015) 0.85
Gene expression modifications in Wharton's Jelly mesenchymal stem cells promoted by prolonged in vitro culturing. BMC Genomics (2013) 0.81
C/EBPδ gene targets in human keratinocytes. PLoS One (2010) 0.79
Differential network analysis applied to preoperative breast cancer chemotherapy response. PLoS One (2013) 0.77
Intensive insulin therapy in the medical ICU. N Engl J Med (2006) 22.37
Assessing computational tools for the discovery of transcription factor binding sites. Nat Biotechnol (2005) 14.29
The Polycomb group protein EZH2 directly controls DNA methylation. Nature (2005) 13.67
Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes. N Engl J Med (2005) 10.16
BioMart and Bioconductor: a powerful link between biological databases and microarray data analysis. Bioinformatics (2005) 9.84
Gene prioritization through genomic data fusion. Nat Biotechnol (2006) 7.48
PlantCARE, a database of plant cis-acting regulatory elements and a portal to tools for in silico analysis of promoter sequences. Nucleic Acids Res (2002) 6.43
Outcome benefit of intensive insulin therapy in the critically ill: Insulin dose versus glycemic control. Crit Care Med (2003) 5.92
High-throughput detection of actionable genomic alterations in clinical tumor samples by targeted, massively parallel sequencing. Cancer Discov (2011) 5.30
Vitamin D and human health: lessons from vitamin D receptor null mice. Endocr Rev (2008) 5.28
Vitamin D deficiency is highly prevalent in COPD and correlates with variants in the vitamin D-binding gene. Thorax (2009) 4.86
A Gibbs sampling method to detect overrepresented motifs in the upstream regions of coexpressed genes. J Comput Biol (2002) 4.05
High doses of vitamin D to reduce exacerbations in chronic obstructive pulmonary disease: a randomized trial. Ann Intern Med (2012) 3.99
Functional diversity of protein phosphatase-1, a cellular economizer and reset button. Physiol Rev (2004) 3.82
Toucan: deciphering the cis-regulatory logic of coregulated genes. Nucleic Acids Res (2003) 3.68
Interleukin-17 orchestrates the granulocyte influx into airways after allergen inhalation in a mouse model of allergic asthma. Am J Respir Cell Mol Biol (2003) 3.60
Intensive insulin therapy in mixed medical/surgical intensive care units: benefit versus harm. Diabetes (2006) 3.56
Immunoregulation by 1,25-dihydroxyvitamin D3: basic concepts. J Steroid Biochem Mol Biol (2005) 3.44
Vitamin D: modulator of the immune system. Curr Opin Pharmacol (2010) 3.31
Intrinsic gene expression profiles of gliomas are a better predictor of survival than histology. Cancer Res (2009) 3.22
Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations. Nat Genet (2013) 3.19
Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1. Nat Med (2003) 3.17
Role of PFKFB3-driven glycolysis in vessel sprouting. Cell (2013) 3.04
Versatile gene-specific sequence tags for Arabidopsis functional genomics: transcript profiling and reverse genetics applications. Genome Res (2004) 3.02
Initiation and execution of lipotoxic ER stress in pancreatic beta-cells. J Cell Sci (2008) 2.99
Advantages and limitations of current network inference methods. Nat Rev Microbiol (2010) 2.97
Computational detection of cis -regulatory modules. Bioinformatics (2003) 2.89
Insulin degludec versus insulin glargine in insulin-naive patients with type 2 diabetes: a 1-year, randomized, treat-to-target trial (BEGIN Once Long). Diabetes Care (2012) 2.89
SynTReN: a generator of synthetic gene expression data for design and analysis of structure learning algorithms. BMC Bioinformatics (2006) 2.82
TOUCAN 2: the all-inclusive open source workbench for regulatory sequence analysis. Nucleic Acids Res (2005) 2.68
Comparison and meta-analysis of microarray data: from the bench to the computer desk. Trends Genet (2003) 2.54
The extended PP1 toolkit: designed to create specificity. Trends Biochem Sci (2010) 2.51
RNA amplification results in reproducible microarray data with slight ratio bias. Biotechniques (2002) 2.49
A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell death. EMBO J (2012) 2.45
Impaired angiogenesis and endochondral bone formation in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188. Mech Dev (2002) 2.39
ENDEAVOUR update: a web resource for gene prioritization in multiple species. Nucleic Acids Res (2008) 2.31
Biomarkers of endometriosis. Fertil Steril (2013) 2.28
Association of hypogonadism with vitamin D status: the European Male Ageing Study. Eur J Endocrinol (2011) 2.28
Leaf mitochondria modulate whole cell redox homeostasis, set antioxidant capacity, and determine stress resistance through altered signaling and diurnal regulation. Plant Cell (2003) 2.22
Sexual dysfunction in women with type 1 diabetes: a controlled study. Diabetes Care (2002) 2.20
Docking motif-guided mapping of the interactome of protein phosphatase-1. Chem Biol (2009) 2.17
INCLUSive: integrated clustering, upstream sequence retrieval and motif sampling. Bioinformatics (2002) 2.13
NuSAP, a novel microtubule-associated protein involved in mitotic spindle organization. J Cell Biol (2003) 2.13
Need for additional calcium to reduce the risk of hip fracture with vitamin d supplementation: evidence from a comparative metaanalysis of randomized controlled trials. J Clin Endocrinol Metab (2007) 2.11
Polymorphisms in innate immunity genes predispose to bacteremia and death in the medical intensive care unit. Crit Care Med (2009) 2.10
Normocalcemia is maintained in mice under conditions of calcium malabsorption by vitamin D-induced inhibition of bone mineralization. J Clin Invest (2012) 2.10
NPP-type ectophosphodiesterases: unity in diversity. Trends Biochem Sci (2005) 2.08
False-positive detection of recombinant human erythropoietin in urine following strenuous physical exercise. Blood (2006) 2.06
Using ribosomal protein genes as reference: a tale of caution. PLoS One (2008) 2.06
Genome-wide analysis of gene expression profiles associated with cell cycle transitions in growing organs of Arabidopsis. Plant Physiol (2005) 2.06
Androgens and bone. Endocr Rev (2004) 2.06
Molecular karyotyping: array CGH quality criteria for constitutional genetic diagnosis. J Histochem Cytochem (2005) 2.05
Analysis of mitosis and antimitotic drug responses in tumors by in vivo microscopy and single-cell pharmacodynamics. Cancer Res (2011) 1.99
Predicting the prognosis of breast cancer by integrating clinical and microarray data with Bayesian networks. Bioinformatics (2006) 1.95
Bone turnover in prolonged critical illness: effect of vitamin D. J Clin Endocrinol Metab (2003) 1.92
Loss of Rb proteins causes genomic instability in the absence of mitogenic signaling. Genes Dev (2010) 1.88
Clinical review: Intensive insulin therapy in critically ill patients: NICE-SUGAR or Leuven blood glucose target? J Clin Endocrinol Metab (2009) 1.84
Monocytes from type 2 diabetic patients have a pro-inflammatory profile. 1,25-Dihydroxyvitamin D(3) works as anti-inflammatory. Diabetes Res Clin Pract (2006) 1.84
Reversal of autoimmune diabetes by restoration of antigen-specific tolerance using genetically modified Lactococcus lactis in mice. J Clin Invest (2012) 1.84
13th Workshop consensus for vitamin D nutritional guidelines. J Steroid Biochem Mol Biol (2007) 1.83
Prevalence and predictors of sexual dysfunction in patients with type 1 diabetes. Diabetes Care (2003) 1.82
Biclustering microarray data by Gibbs sampling. Bioinformatics (2003) 1.82
Molecular response to cetuximab and efficacy of preoperative cetuximab-based chemoradiation in rectal cancer. J Clin Oncol (2009) 1.82
Pocket protein complexes are recruited to distinct targets in quiescent and proliferating cells. Mol Cell Biol (2005) 1.81
Structural basis of substrate discrimination and integrin binding by autotaxin. Nat Struct Mol Biol (2011) 1.81
TRPV4-mediated calcium influx regulates terminal differentiation of osteoclasts. Cell Metab (2008) 1.79
A structural basis for the unique binding features of the human vitamin D-binding protein. Nat Struct Biol (2002) 1.78
Draft Genome Sequence of Lysobacter capsici AZ78, a Bacterium Antagonistic to Plant-Pathogenic Oomycetes. Genome Announc (2014) 1.77
Benchmarking the CATMA microarray. A novel tool for Arabidopsis transcriptome analysis. Plant Physiol (2005) 1.76
Vitamin D: a pleiotropic hormone. Kidney Int (2010) 1.76
Vitamin D receptor in chondrocytes promotes osteoclastogenesis and regulates FGF23 production in osteoblasts. J Clin Invest (2006) 1.75
Vitamin D and cancer. J Steroid Biochem Mol Biol (2006) 1.72
Soluble VEGF isoforms are essential for establishing epiphyseal vascularization and regulating chondrocyte development and survival. J Clin Invest (2004) 1.72
Degeneracy and function of the ubiquitous RVXF motif that mediates binding to protein phosphatase-1. J Biol Chem (2003) 1.72
TXTGate: profiling gene groups with text-based information. Genome Biol (2004) 1.72
arrayCGHbase: an analysis platform for comparative genomic hybridization microarrays. BMC Bioinformatics (2005) 1.71
A guide to web tools to prioritize candidate genes. Brief Bioinform (2010) 1.70
PKA and Sch9 control a molecular switch important for the proper adaptation to nutrient availability. Mol Microbiol (2005) 1.69
Adaptive quality-based clustering of gene expression profiles. Bioinformatics (2002) 1.68
Comprehensive analysis of the base composition around the transcription start site in Metazoa. BMC Genomics (2004) 1.68
Cellular islet autoimmunity associates with clinical outcome of islet cell transplantation. PLoS One (2008) 1.67