PubRank

Roger Bouillon

Author PubWeight™ 176.17‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Intensive insulin therapy in the medical ICU. N Engl J Med 2006 22.37
2 Outcome benefit of intensive insulin therapy in the critically ill: Insulin dose versus glycemic control. Crit Care Med 2003 5.92
3 Vitamin D deficiency is highly prevalent in COPD and correlates with variants in the vitamin D-binding gene. Thorax 2009 4.86
4 High doses of vitamin D to reduce exacerbations in chronic obstructive pulmonary disease: a randomized trial. Ann Intern Med 2012 3.99
5 Intensive insulin therapy in mixed medical/surgical intensive care units: benefit versus harm. Diabetes 2006 3.56
6 Impaired angiogenesis and endochondral bone formation in mice lacking the vascular endothelial growth factor isoforms VEGF164 and VEGF188. Mech Dev 2002 2.39
7 Association of hypogonadism with vitamin D status: the European Male Ageing Study. Eur J Endocrinol 2011 2.28
8 NuSAP, a novel microtubule-associated protein involved in mitotic spindle organization. J Cell Biol 2003 2.13
9 Need for additional calcium to reduce the risk of hip fracture with vitamin d supplementation: evidence from a comparative metaanalysis of randomized controlled trials. J Clin Endocrinol Metab 2007 2.11
10 Normocalcemia is maintained in mice under conditions of calcium malabsorption by vitamin D-induced inhibition of bone mineralization. J Clin Invest 2012 2.10
11 Androgens and bone. Endocr Rev 2004 2.06
12 Bone turnover in prolonged critical illness: effect of vitamin D. J Clin Endocrinol Metab 2003 1.92
13 Clinical review: Intensive insulin therapy in critically ill patients: NICE-SUGAR or Leuven blood glucose target? J Clin Endocrinol Metab 2009 1.84
14 Monocytes from type 2 diabetic patients have a pro-inflammatory profile. 1,25-Dihydroxyvitamin D(3) works as anti-inflammatory. Diabetes Res Clin Pract 2006 1.84
15 13th Workshop consensus for vitamin D nutritional guidelines. J Steroid Biochem Mol Biol 2007 1.83
16 TRPV4-mediated calcium influx regulates terminal differentiation of osteoclasts. Cell Metab 2008 1.79
17 A structural basis for the unique binding features of the human vitamin D-binding protein. Nat Struct Biol 2002 1.78
18 Vitamin D: a pleiotropic hormone. Kidney Int 2010 1.76
19 Vitamin D receptor in chondrocytes promotes osteoclastogenesis and regulates FGF23 production in osteoblasts. J Clin Invest 2006 1.75
20 Soluble VEGF isoforms are essential for establishing epiphyseal vascularization and regulating chondrocyte development and survival. J Clin Invest 2004 1.72
21 Vitamin D beyond bones in chronic obstructive pulmonary disease: time to act. Am J Respir Crit Care Med 2009 1.63
22 Hypogonadism, quadriceps weakness, and exercise intolerance in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2005 1.61
23 Cortisol response to critical illness: effect of intensive insulin therapy. J Clin Endocrinol Metab 2006 1.60
24 Vitamin D and diabetes. Endocrinol Metab Clin North Am 2010 1.52
25 Identification of 70 calcium-sensing receptor mutations in hyper- and hypo-calcaemic patients: evidence for clustering of extracellular domain mutations at calcium-binding sites. Hum Mol Genet 2012 1.51
26 The E2F-regulated gene Chk1 is highly expressed in triple-negative estrogen receptor /progesterone receptor /HER-2 breast carcinomas. Cancer Res 2007 1.48
27 Association between 25-hydroxyvitamin D levels and cognitive performance in middle-aged and older European men. J Neurol Neurosurg Psychiatry 2009 1.44
28 1,25-Dihydroxyvitamin D3 modulates expression of chemokines and cytokines in pancreatic islets: implications for prevention of diabetes in nonobese diabetic mice. Endocrinology 2005 1.39
29 Placental growth factor mediates mesenchymal cell development, cartilage turnover, and bone remodeling during fracture repair. J Clin Invest 2006 1.39
30 Immune regulation of 25-hydroxyvitamin-D3-1alpha-hydroxylase in human monocytes. J Bone Miner Res 2005 1.37
31 Active intestinal calcium transport in the absence of transient receptor potential vanilloid type 6 and calbindin-D9k. Endocrinology 2008 1.36
32 Differential regulation of bone and body composition in male mice with combined inactivation of androgen and estrogen receptor-alpha. FASEB J 2008 1.31
33 Analogs of 1alpha,25-dihydroxyvitamin D3 as pluripotent immunomodulators. J Cell Biochem 2003 1.31
34 The vitamin D receptor gene FokI polymorphism: functional impact on the immune system. Eur J Immunol 2007 1.28
35 Reducing fracture risk with calcium and vitamin D. Clin Endocrinol (Oxf) 2010 1.28
36 Vitamin D-binding protein and vitamin D in blacks and whites. N Engl J Med 2014 1.27
37 Perchlorate versus other environmental sodium/iodide symporter inhibitors: potential thyroid-related health effects. Eur J Endocrinol 2006 1.23
38 14th Vitamin D Workshop consensus on vitamin D nutritional guidelines. J Steroid Biochem Mol Biol 2010 1.20
39 Vitamin D nutritional policy needs a vision for the future. Exp Biol Med (Maywood) 2010 1.19
40 Relative impact of androgen and estrogen receptor activation in the effects of androgens on trabecular and cortical bone in growing male mice: a study in the androgen receptor knockout mouse model. J Bone Miner Res 2006 1.17
41 Vitamin D, parathyroid hormone and the metabolic syndrome in middle-aged and older European men. Eur J Endocrinol 2009 1.14
42 Musculoskeletal pain is associated with very low levels of vitamin D in men: results from the European Male Ageing Study. Ann Rheum Dis 2010 1.14
43 Redirection of human autoreactive T-cells Upon interaction with dendritic cells modulated by TX527, an analog of 1,25 dihydroxyvitamin D(3). Diabetes 2002 1.13
44 Age-, gender-, and weight-related effects on levels of 25-hydroxyvitamin D are not mediated by vitamin D binding protein. Clin Endocrinol (Oxf) 2007 1.12
45 Vitamin D status at breast cancer diagnosis: correlation with tumor characteristics, disease outcome, and genetic determinants of vitamin D insufficiency. Carcinogenesis 2012 1.12
46 The combined administration of GH-releasing peptide-2 (GHRP-2), TRH and GnRH to men with prolonged critical illness evokes superior endocrine and metabolic effects compared to treatment with GHRP-2 alone. Clin Endocrinol (Oxf) 2002 1.11
47 Differential effects on bone of estrogen receptor alpha and androgen receptor activation in orchidectomized adult male mice. Proc Natl Acad Sci U S A 2003 1.11
48 Clinical Review: Sex steroids and the periosteum--reconsidering the roles of androgens and estrogens in periosteal expansion. J Clin Endocrinol Metab 2005 1.10
49 Impact of androgens, growth hormone, and IGF-I on bone and muscle in male mice during puberty. J Bone Miner Res 2007 1.06
50 1,25-Dihydroxyvitamin D3 inhibits ultraviolet B-induced apoptosis, Jun kinase activation, and interleukin-6 production in primary human keratinocytes. J Cell Biochem 2003 1.04
51 Musculoskeletal effects of the recombinant human IGF-I/IGF binding protein-3 complex in osteoporotic patients with proximal femoral fracture: a double-blind, placebo-controlled pilot study. J Clin Endocrinol Metab 2002 1.04
52 A thyroid thriller: acute transient and symmetric goiter after fine-needle aspiration of a solitary thyroid nodule. Thyroid 2008 1.03
53 Evidence from data searches and life-table analyses for gender-related differences in absolute risk of hip fracture after Colles' or spine fracture: Colles' fracture as an early and sensitive marker of skeletal fragility in white men. J Bone Miner Res 2004 1.02
54 Does the phosphate binder lanthanum carbonate affect bone in rats with chronic renal failure? J Am Soc Nephrol 2004 1.02
55 Lower vitamin D levels are associated with depression among community-dwelling European men. J Psychopharmacol 2010 1.02
56 VDR-dependent regulation of mast cell maturation mediated by 1,25-dihydroxyvitamin D3. J Leukoc Biol 2006 1.00
57 1,25-Dihydroxyvitamin D3 and analogues protect primary human keratinocytes against UVB-induced DNA damage. J Photochem Photobiol B 2005 1.00
58 Clinical relevance of thyroid fluorodeoxyglucose-whole body positron emission tomography incidentaloma. J Clin Endocrinol Metab 2002 0.98
59 Anti-placental growth factor reduces bone metastasis by blocking tumor cell engraftment and osteoclast differentiation. Cancer Res 2010 0.97
60 1,25-dihydroxyvitamin D3 influences cellular homocysteine levels in murine preosteoblastic MC3T3-E1 cells by direct regulation of cystathionine β-synthase. J Bone Miner Res 2011 0.97
61 Vitamin D and 1,25-dihydroxyvitamin D3 as modulators in the immune system. J Steroid Biochem Mol Biol 2004 0.97
62 Defect in activation-induced cell death in non-obese diabetic (NOD) T lymphocytes. J Autoimmun 2003 0.96
63 Development of a method for the quantification of 1alpha,25(OH)2-vitamin D3 in serum by liquid chromatography tandem mass spectrometry without derivatization. Eur J Mass Spectrom (Chichester, Eng) 2010 0.96
64 Insulin-like growth factor-1-mediated AKT activation postpones the onset of ultraviolet B-induced apoptosis, providing more time for cyclobutane thymine dimer removal in primary human keratinocytes. J Biol Chem 2002 0.95
65 Optimal control of glycemia among critically ill patients. JAMA 2004 0.94
66 The effects of 1alpha,25-dihydroxyvitamin D3 on the expression of DNA replication genes. J Bone Miner Res 2004 0.94
67 Unaltered diabetes presentation in NOD mice lacking the vitamin D receptor. Diabetes 2007 0.94
68 Immune regulation of 25-hydroxyvitamin D-1alpha-hydroxylase in human monocytic THP1 cells: mechanisms of interferon-gamma-mediated induction. J Clin Endocrinol Metab 2006 0.94
69 Human growth hormone replacement in adult hypopituitary patients: long-term effects on body composition and lipid status--3-year results from the HypoCCS Database. J Clin Endocrinol Metab 2002 0.93
70 The effects of growth hormone replacement therapy on bone metabolism in adult-onset growth hormone deficiency: a 2-year open randomized controlled multicenter trial. J Bone Miner Res 2002 0.92
71 Novel insights in the immune function of the vitamin D system: synergism with interferon-beta. J Steroid Biochem Mol Biol 2006 0.91
72 Superagonistic action of 14-epi-analogs of 1,25-dihydroxyvitamin D explained by vitamin D receptor-coactivator interaction. Mol Pharmacol 2005 0.91
73 Bone and metabolism: a complex crosstalk. Horm Res 2009 0.91
74 Regulation of 25-hydroxyvitamin d-1alpha-hydroxylase by IFNgamma in human monocytic THP1 cells. J Steroid Biochem Mol Biol 2004 0.91
75 A homozygous inactivating calcium-sensing receptor mutation, Pro339Thr, is associated with isolated primary hyperparathyroidism: correlation between location of mutations and severity of hypercalcaemia. Clin Endocrinol (Oxf) 2010 0.90
76 Role of the androgen receptor in skeletal homeostasis: the androgen-resistant testicular feminized male mouse model. J Bone Miner Res 2004 0.90
77 GNAS defects identified by stimulatory G protein alpha-subunit signalling studies in platelets. J Clin Endocrinol Metab 2008 0.90
78 Two 14-epi analogues of 1,25-dihydroxyvitamin D3 protect human keratinocytes against the effects of UVB. Arch Dermatol Res 2004 0.90
79 Deletion of the vitamin D receptor specifically in the parathyroid demonstrates a limited role for the receptor in parathyroid physiology. Am J Physiol Renal Physiol 2009 0.90
80 Prevalence and incidence of diabetes mellitus in adult patients on growth hormone replacement for growth hormone deficiency: a surveillance database analysis. J Clin Endocrinol Metab 2011 0.89
81 Current evidence for recommendation of surgery, medical treatment and vitamin D repletion in mild primary hyperparathyroidism. Eur J Endocrinol 2011 0.88
82 A new approach to imprinting mutation detection in GNAS by Sequenom EpiTYPER system. Clin Chim Acta 2010 0.88
83 UVB-induced production of 1,25-dihydroxyvitamin D3 and vitamin D activity in human keratinocytes pretreated with a sterol delta7-reductase inhibitor. J Cell Biochem 2006 0.88
84 Growth without growth hormone receptor: estradiol is a major growth hormone-independent regulator of hepatic IGF-I synthesis. J Bone Miner Res 2005 0.88
85 Characterization of the condensin component Cnap1 and protein kinase Melk as novel E2F target genes down-regulated by 1,25-dihydroxyvitamin D3. J Biol Chem 2005 0.86
86 1,25-dihydroxyvitamin D3 and a superagonistic analog in combination with paclitaxel or suberoylanilide hydroxamic acid have potent antiproliferative effects on anaplastic thyroid cancer. J Steroid Biochem Mol Biol 2010 0.86
87 Glucose control in critically ill patients. N Engl J Med 2009 0.86
88 Vitamin D and diabetes. Rheum Dis Clin North Am 2012 0.86
89 The impact of 1,25(OH)2D3 and its structural analogs on gene expression in cancer cells--a microarray approach. Anticancer Res 2009 0.86
90 A novel nonsense mutation in the ligand binding domain of the vitamin D receptor causes hereditary 1,25-dihydroxyvitamin D-resistant rickets. Mol Genet Metab 2002 0.85
91 Molecular pathways involved in the anti-apoptotic effect of 1,25-dihydroxyvitamin D3 in primary human keratinocytes. J Cell Biochem 2004 0.85
92 Acute shock induced by antigen vaccination in NOD mice. Diabetes 2003 0.85
93 Vitamin D deficiency. N Engl J Med 2007 0.84
94 Superagonistic fluorinated vitamin D3 analogs stabilize helix 12 of the vitamin D receptor. Chem Biol 2008 0.84
95 1 Alpha,25-dihydroxyvitamin D3 and its TX527 analog inhibit the growth of endothelial cells transformed by Kaposi sarcoma-associated herpes virus G protein-coupled receptor in vitro and in vivo. Endocrinology 2009 0.84
96 The Impact of congenital, severe, untreated growth hormone (GH) deficiency on bone size and density in young adults: insights from genetic GH-releasing hormone receptor deficiency. J Clin Endocrinol Metab 2003 0.83
97 Growth hormone and bone health. Horm Res 2003 0.83
98 Actin-DBP: the perfect structural fit? Acta Crystallogr D Biol Crystallogr 2003 0.81
99 Higher 25(OH)D2 is associated with lower 25(OH)D3 and 1,25(OH)2D3. J Clin Endocrinol Metab 2014 0.81
100 The diagnosis and treatment of male osteoporosis: Defining, assessing, and preventing skeletal fragility in men. Eur J Intern Med 2007 0.81
101 Disorders of calcium homeostasis. Best Pract Res Clin Endocrinol Metab 2003 0.80
102 AKT status controls susceptibility of malignant keratinocytes to the early-activated and UVB-induced apoptotic pathway. J Invest Dermatol 2004 0.80
103 Vitamin D analogs and coactivators. Anticancer Res 2006 0.80
104 1alpha,25-Dihydroxyvitamin D3-induced down-regulation of the checkpoint proteins, Chk1 and Claspin, is mediated by the pocket proteins p107 and p130. J Steroid Biochem Mol Biol 2006 0.80
105 Emergencies of calcium homeostasis. Rev Endocr Metab Disord 2003 0.79
106 NOD bone marrow-derived dendritic cells are modulated by analogs of 1,25-dihydroxyvitamin D3. J Steroid Biochem Mol Biol 2004 0.79
107 Microarray analysis of 1alpha,25-dihydroxyvitamin D3-treated MC3T3-E1 cells. J Steroid Biochem Mol Biol 2004 0.79
108 Bone and muscle protective potential of the prostate-sparing synthetic androgen 7alpha-methyl-19-nortestosterone: evidence from the aged orchidectomized male rat model. Bone 2005 0.79
109 Neuroendocrine tumor markers and enterochromaffin-like cell hyper/dysplasia in type 1 diabetes. Diabetes Care 2004 0.79
110 Vitamin D in thyroid tumorigenesis and development. Prog Histochem Cytochem 2013 0.79
111 UVB-induced 1,25(OH)2D3 production and vitamin D activity in intestinal CaCo-2 cells and in THP-1 macrophages pretreated with a sterol Delta7-reductase inhibitor. J Cell Biochem 2006 0.79
112 Perturbed insulin-like growth factor-1 (IGF-1) and IGF binding protein-3 are not associated with chronic widespread pain in men: results from the European Male Ageing Study. J Rheumatol 2009 0.79
113 Insulin and pentastarch for severe sepsis. N Engl J Med 2008 0.78
114 Physical activity in the androgen receptor knockout mouse: evidence for reversal of androgen deficiency on cancellous bone. Biochem Biophys Res Commun 2008 0.78
115 Clinical applications for vitamin D assays: what is known and what is wished for. Clin Chem 2011 0.78
116 1,25-Dihydroxyvitamin D3 and the aging-related forkhead box O and sestrin proteins in osteoblasts. J Steroid Biochem Mol Biol 2012 0.78
117 Pregnancy in mice lacking the vitamin D receptor: normal maternal skeletal response, but fetal hypomineralization rescued by maternal calcium supplementation. Pediatr Res 2003 0.78
118 Vitamin D(3): synthesis of seco C-9,11,21-trisnor-17-methyl-1 alpha, 25-dihydroxyvitamin D(3) analogues. Bioorg Med Chem Lett 2002 0.77
119 A new missense mutation in the CASR gene in familial interstitial lung disease with hypocalciuric hypercalcemia and defective granulocyte function. Am J Respir Crit Care Med 2008 0.77
120 Vitamin D, mitochondria, and muscle. J Clin Endocrinol Metab 2013 0.77
121 CD-ring modified vitamin D3 analogs and their superagonistic action. J Steroid Biochem Mol Biol 2010 0.77
122 Duodenal calcium absorption in dexamethasone-treated mice: functional and molecular aspects. Arch Biochem Biophys 2006 0.76
123 Growth hormone should be used only for approved indications. J Clin Endocrinol Metab 2013 0.76
124 Dermal fibroblasts pretreated with a sterol Delta7-reductase inhibitor produce 25-hydroxyvitamin D3 upon UVB irradiation. J Photochem Photobiol B 2006 0.76
125 A brown tumor after biliopancreatic diversion for severe obesity. Endocr J 2008 0.76
126 Synthesis, structure, and biological activity of des-side chain analogues of 1α,25-dihydroxyvitamin D3 with substituents at C18. ChemMedChem 2011 0.76
127 [Vitamin D and human health]. Presse Med 2008 0.76
128 Antiproliferative and calcemic actions of trans-decalin CD-ring analogs of 1,25-dihydroxyvitamin D3. Anticancer Res 2009 0.76
129 Vitamin D and cancer. Cell Cycle 2013 0.75
130 Microarray analysis of MCF-7 breast cancer cells treated with 1,25-dihydroxyvitamin D3 or a 17-methyl-D-ring analog. Anticancer Res 2009 0.75
131 Altered Vitamin D receptor-coactivator interactions reflect superagonism of Vitamin D analogs. J Steroid Biochem Mol Biol 2005 0.75
132 Seasonality of birth in patients with type 1 diabetes. Lancet 2002 0.75
133 Synthesis of spiro[4.5]decane CF-ring analogues of 1 alpha,25-dihydroxyvitamin D3. Org Lett 2006 0.75
134 The sunshine hormone vitamin D and its association with type 1 diabetes. Discov Med 2005 0.75
135 Removal of C-ring from the CD-ring skeleton of 1alpha,25-dihydroxyvitamin D3 does not alter its target tissue metabolism significantly. Arch Biochem Biophys 2006 0.75
136 Synthesis, biological activity, and conformational analysis of CD-ring modified trans-decalin 1 alpha,25-dihydroxyvitamin D analogs. Org Biomol Chem 2003 0.75
137 Previtamin D3 with a trans-fused decalin CD-ring has pronounced genomic activity. J Biol Chem 2003 0.75
138 The development of CD-ring modified analogs of 1alpha,25-dihydroxyvitamin D. J Steroid Biochem Mol Biol 2007 0.75
139 Synthesis and biological activity of 22-oxa CD-ring modified analogues of 1alpha,25-dihydroxyvitamin D3: cis-perhydrindane CE-ring analogues. Bioorg Med Chem Lett 2004 0.75
140 Chemoenzymatic synthesis and biological evaluation of C-3 carbamate analogues of 1alpha,25-dihydroxyvitamin D3. Bioorg Med Chem 2004 0.75
141 Versatile synthesis and biological evaluation of 1,3-diamino-substituted 1alpha,25-dihydroxyvitamin D3 analogues. Bioorg Med Chem 2005 0.75
142 Rickets in transgenic animals. Endocr Dev 2003 0.75
143 Novel A-ring homodimeric C-3-carbamate analogues of 1alpha,25-dihydroxyvitamin D3: synthesis and preliminary biological evaluation. Bioorg Med Chem 2006 0.75
144 Biological activity and conformational analysis of C20 and C14 epimers of CD-ring modified trans-decalin 1alpha,25-dihydroxyvitamin D analogs. J Steroid Biochem Mol Biol 2004 0.75
145 Optimizing the benefits of bisphosphonates in osteoporosis : the importance of appropriate calcium intake. Treat Endocrinol 2006 0.75
146 Hypogonadism in male outpatients with sarcoidosis. Respir Med 2007 0.75
147 Synthesis and biological activity of 22-oxa CD-ring modified analogues of 1alpha,25-dihydroxyvitamin D3: spiro[5.5]undecane CF-ring analogues. Bioorg Med Chem Lett 2004 0.75
148 Fifteenth vitamin D workshop. J Steroid Biochem Mol Biol 2013 0.75
149 Vitamin D(3): synthesis of seco-C-9,11-bisnor-17-methyl-1 alpha,25-dihydroxyvitamin D(3) analogues. Bioorg Med Chem Lett 2002 0.75