James P O'Callaghan

Author PubWeight™ 53.81‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Time course of the development of Alzheimer-like pathology in the doubly transgenic PS1+APP mouse. Exp Neurol 2002 1.89
2 Mice deficient in TNF receptors are protected against dopaminergic neurotoxicity: implications for Parkinson's disease. FASEB J 2002 1.79
3 Neuroendocrine aspects of the response to stress. Metabolism 2002 1.71
4 Deficiency of TNF receptors suppresses microglial activation and alters the susceptibility of brain regions to MPTP-induced neurotoxicity: role of TNF-alpha. FASEB J 2006 1.61
5 Induction of gp130-related cytokines and activation of JAK2/STAT3 pathway in astrocytes precedes up-regulation of glial fibrillary acidic protein in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of neurodegeneration: key signaling pathway for astrogliosis in vivo? J Biol Chem 2004 1.57
6 Divergent roles for tumor necrosis factor-alpha in the brain. J Neuroimmune Pharmacol 2007 1.54
7 Work, obesity, and occupational safety and health. Am J Public Health 2007 1.53
8 Minocycline attenuates microglial activation but fails to mitigate striatal dopaminergic neurotoxicity: role of tumor necrosis factor-alpha. J Neurochem 2006 1.49
9 Distinct roles of PDE4 and PDE10A in the regulation of cAMP/PKA signaling in the striatum. J Neurosci 2008 1.48
10 Preliminary study of the plasma and cerebrospinal fluid concentrations of IL-6 and IL-10 in patients with chronic pain receiving intrathecal opioid infusions by chronically implanted pump for pain management. Pain Med 2010 1.47
11 Astrogliosis in CNS pathologies: is there a role for microglia? Mol Neurobiol 2010 1.38
12 Vacuolar leukoencephalopathy with widespread astrogliosis in mice lacking transcription factor Nrf2. Am J Pathol 2007 1.31
13 Mechanism of age-dependent susceptibility and novel treatment strategy in glutaric acidemia type I. J Clin Invest 2007 1.07
14 Striatal dysregulation of Cdk5 alters locomotor responses to cocaine, motor learning, and dendritic morphology. Proc Natl Acad Sci U S A 2008 1.04
15 Sample-dependent effects on the neuropeptidome detected in rat brain tissue preparations by capillary liquid chromatography with tandem mass spectrometry. Anal Chem 2005 1.03
16 A randomized, controlled trial of oxycodone versus placebo in patients with postherpetic neuralgia and painful diabetic neuropathy treated with pregabalin. J Pain 2009 1.02
17 Identification and quantification of neuropeptides in brain tissue by capillary liquid chromatography coupled off-line to MALDI-TOF and MALDI-TOF/TOF-MS. Anal Chem 2006 1.00
18 Chronic exposure to corticosterone enhances the neuroinflammatory and neurotoxic responses to methamphetamine. J Neurochem 2012 0.98
19 Elevated environmental temperature and methamphetamine neurotoxicity. Environ Res 2003 0.98
20 Mild steel welding fume causes manganese accumulation and subtle neuroinflammatory changes but not overt neuronal damage in discrete brain regions of rats after short-term inhalation exposure. Neurotoxicology 2009 0.94
21 AMP-activated protein kinase phosphorylation in brain is dependent on method of killing and tissue preparation. J Neurochem 2007 0.93
22 Low-level human equivalent gestational lead exposure produces supernormal scotopic electroretinograms, increased retinal neurogenesis, and decreased retinal dopamine utilization in rats. Environ Health Perspect 2008 0.93
23 Systems analysis of genetic variation in MPTP neurotoxicity in mice. Neurotoxicology 2013 0.92
24 Recapitulation of cell signaling events associated with astrogliosis using the brain slice preparation. J Neurochem 2006 0.92
25 Do early-life insults contribute to the late-life development of Parkinson and Alzheimer diseases? Metabolism 2008 0.92
26 NeuroAIDS, drug abuse, and inflammation: building collaborative research activities. J Neuroimmune Pharmacol 2006 0.91
27 Organophosphates dysregulate dopamine signaling, glutamatergic neurotransmission, and induce neuronal injury markers in striatum. J Neurochem 2011 0.90
28 Depression, cytokines, and glial function. Metabolism 2005 0.88
29 Associations of cortical astrogliosis with cognitive performance and dementia status. J Alzheimers Dis 2004 0.87
30 An update on the pharmacological management of post-herpetic neuralgia and painful diabetic neuropathy. CNS Drugs 2008 0.86
31 Calcium/calmodulin-dependent protein kinase II activity and expression are altered in the hippocampus of Pb2+-exposed rats. Brain Res 2005 0.86
32 Autoantibodies to neurotypic and gliotypic proteins as biomarkers of neurotoxicity: assessment of trimethyltin (TMT). Neurotoxicology 2007 0.86
33 Chronic treatment with supraphysiological levels of corticosterone enhances D-MDMA-induced dopaminergic neurotoxicity in the C57BL/6J female mouse. Brain Res 2002 0.85
34 Personalized medicine in major depressive disorder -- opportunities and pitfalls. Metabolism 2012 0.85
35 Selective changes in gene expression in cortical regions sensitive to amphetamine during the neurodegenerative process. Neurotoxicology 2004 0.83
36 The pharmacology of wakefulness. Metabolism 2006 0.83
37 Gestational lead exposure selectively decreases retinal dopamine amacrine cells and dopamine content in adult mice. Toxicol Appl Pharmacol 2011 0.81
38 Brain organochlorines and Lewy pathology: the Honolulu-Asia Aging Study. Mov Disord 2012 0.81
39 Brain concentrations of d-MDMA are increased after stress. Psychopharmacology (Berl) 2004 0.81
40 Effects of repeated treatment with phosphodiesterase-4 inhibitors on cAMP signaling, hippocampal cell proliferation, and behavior in the forced-swim test. J Pharmacol Exp Ther 2011 0.81
41 Development of an animal model to study the potential neurotoxic effects associated with welding fume inhalation. Neurotoxicology 2006 0.80
42 d-MDMA during vitamin E deficiency: effects on dopaminergic neurotoxicity and hepatotoxicity. Brain Res 2002 0.80
43 Neurotoxic esterase: not so toxic? Nat Genet 2003 0.79
44 Nerve agent exposure elicits site-specific changes in protein phosphorylation in mouse brain. Brain Res 2010 0.79
45 Corticosterone regulates expression of CCL2 in the intact and chemically injured hippocampus. Neurosci Lett 2006 0.78
46 Indirubins deplete striatal monoamines in the Intact and MPTP-treated mouse brain and block kainate-induced striatal astrogliosis. Neurotoxicol Teratol 2009 0.78
47 Functional profile of a novel modulator of serotonin, dopamine, and glutamate neurotransmission. Psychopharmacology (Berl) 2014 0.77
48 Time-dependent slowly-reversible inhibition of monoamine oxidase A by N-substituted 1,2,3,6-tetrahydropyridines. Bioorg Med Chem 2011 0.77
49 Regulatory developmental neurotoxicity testing: a model study focussing on conventional neuropathology endpoints and other perspectives. Environ Toxicol Pharmacol 2005 0.76
50 Neuronal and astroglial responses to the serotonin and norepinephrine neurotoxin: 1-methyl-4-(2'-aminophenyl)-1,2,3,6-tetrahydropyridine. J Pharmacol Exp Ther 2003 0.76
51 Protracted exposure to supraphysiological levels of corticosterone does not cause neuronal loss or damage and protects against kainic acid-induced neurotoxicity in the hippocampus of C57BL/6J mice. Neurotoxicology 2009 0.76
52 Microscale sample deposition onto hydrophobic target plates for trace level detection of neuropeptides in brain tissue by MALDI-MS. J Mass Spectrom 2005 0.76
53 Discovery of novel alpha7 nicotinic receptor antagonists. Bioorg Med Chem Lett 2010 0.76