Published in J Biol Chem on March 02, 2004
Genomic analysis of reactive astrogliosis. J Neurosci (2012) 3.62
STAT3 is a critical regulator of astrogliosis and scar formation after spinal cord injury. J Neurosci (2008) 3.44
Induction of glial fibrillary acidic protein expression in astrocytes by nitric oxide. J Neurosci (2006) 1.90
Reactive astrocytes as therapeutic targets for CNS disorders. Neurotherapeutics (2010) 1.60
Differential regulation of STAT family members by glycogen synthase kinase-3. J Biol Chem (2008) 1.41
Lipopolysaccharide-induced interleukin-6 production is controlled by glycogen synthase kinase-3 and STAT3 in the brain. J Neuroinflammation (2009) 1.29
Disruption of astrocyte STAT3 signaling decreases mitochondrial function and increases oxidative stress in vitro. PLoS One (2010) 1.25
Glial development: the crossroads of regeneration and repair in the CNS. Neuron (2014) 1.12
Lipocalin-2 Is a chemokine inducer in the central nervous system: role of chemokine ligand 10 (CXCL10) in lipocalin-2-induced cell migration. J Biol Chem (2011) 1.10
S100B is increased in Parkinson's disease and ablation protects against MPTP-induced toxicity through the RAGE and TNF-α pathway. Brain (2012) 1.07
Conditional deletion of Notch1 and Notch2 genes in excitatory neurons of postnatal forebrain does not cause neurodegeneration or reduction of Notch mRNAs and proteins. J Biol Chem (2012) 1.07
Suppressor of cytokine signaling 3 limits protection of leukemia inhibitory factor receptor signaling against central demyelination. Proc Natl Acad Sci U S A (2006) 1.06
Age exaggerates proinflammatory cytokine signaling and truncates signal transducers and activators of transcription 3 signaling following ischemic stroke in the rat. Neuroscience (2010) 1.03
Chronic perinatal hypoxia reduces glutamate-aspartate transporter function in astrocytes through the Janus kinase/signal transducer and activator of transcription pathway. J Neurosci (2011) 1.02
Chronic exposure to corticosterone enhances the neuroinflammatory and neurotoxic responses to methamphetamine. J Neurochem (2012) 0.98
Astrocytes as a source for extracellular matrix molecules and cytokines. Front Pharmacol (2012) 0.96
Elusive roles for reactive astrocytes in neurodegenerative diseases. Front Cell Neurosci (2015) 0.95
Systems analysis of genetic variation in MPTP neurotoxicity in mice. Neurotoxicology (2013) 0.92
Early activation of STAT3 regulates reactive astrogliosis induced by diverse forms of neurotoxicity. PLoS One (2014) 0.91
Glial fibrillary tangles and JAK/STAT-mediated glial and neuronal cell death in a Drosophila model of glial tauopathy. J Neurosci (2010) 0.90
Reactive astrocytes and therapeutic potential in focal ischemic stroke. Neurobiol Dis (2015) 0.90
Neurotoxicity following acute inhalation exposure to the oil dispersant COREXIT EC9500A. J Toxicol Environ Health A (2011) 0.88
STAT3 but not STAT1 is required for astrocyte differentiation. PLoS One (2014) 0.88
Traumatically injured astrocytes release a proteomic signature modulated by STAT3-dependent cell survival. Glia (2015) 0.87
SN79, a sigma receptor antagonist, attenuates methamphetamine-induced astrogliosis through a blockade of OSMR/gp130 signaling and STAT3 phosphorylation. Exp Neurol (2014) 0.86
Neuroimmune basis of methamphetamine toxicity. Int Rev Neurobiol (2014) 0.86
S-nitrosoglutathione induces ciliary neurotrophic factor expression in astrocytes, which has implications to protect the central nervous system under pathological conditions. J Biol Chem (2012) 0.85
The Role of Astrocytes in Multiple Sclerosis Progression. Front Neurol (2015) 0.84
The Neurogenic Potential of Astrocytes Is Regulated by Inflammatory Signals. Mol Neurobiol (2015) 0.84
Stüve-Wiedemann syndrome: LIFR and associated cytokines in clinical course and etiology. Orphanet J Rare Dis (2014) 0.83
The role of the JAK-STAT pathway in neural stem cells, neural progenitor cells and reactive astrocytes after spinal cord injury. Biomed Rep (2014) 0.81
Inhibition of Drp1 mitochondrial translocation provides neural protection in dopaminergic system in a Parkinson's disease model induced by MPTP. Sci Rep (2016) 0.81
Activation of STAT3 signaling in axotomized neurons and reactive astrocytes after fimbria-fornix transection. Exp Brain Res (2005) 0.81
Astrocyte Activation via Stat3 Signaling Determines the Balance of Oligodendrocyte versus Schwann Cell Remyelination. Am J Pathol (2015) 0.80
Distinct mechanisms of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrimidine resistance revealed by transcriptome mapping in mouse striatum. Neuroscience (2008) 0.80
Translational potential of astrocytes in brain disorders. Prog Neurobiol (2015) 0.80
Role of unphosphorylated transcription factor STAT3 in late cerebral ischemia after subarachnoid hemorrhage. J Cereb Blood Flow Metab (2014) 0.80
Expression of Disabled 1 suppresses astroglial differentiation in neural stem cells. Mol Cell Neurosci (2008) 0.79
GSK3β inhibition protects the immature brain from hypoxic-ischaemic insult via reduced STAT3 signalling. Neuropharmacology (2015) 0.78
The effect of monosodium glutamate on the cerebellar cortex of male albino rats and the protective role of vitamin C (histological and immunohistochemical study). J Mol Histol (2011) 0.78
Astrocytes and lysosomal storage diseases. Neuroscience (2015) 0.78
Inhibition of the Jak-STAT pathway prevents CNTF-mediated survival of axotomized oxytocinergic magnocellular neurons in organotypic cultures of the rat supraoptic nucleus. Exp Neurol (2012) 0.78
Soluble factor effects on glial cell reactivity at the surface of gel-coated microwires. J Neurosci Methods (2010) 0.77
Expression and activation of STAT3 in the astrocytes of optic nerve in a rat model of transient intraocular hypertension. PLoS One (2013) 0.77
Transcriptional upregulation of microtubule-associated protein 2 is involved in the protein kinase A-induced decrease in the invasiveness of glioma cells. Neuro Oncol (2015) 0.77
Ethyl pyruvate promotes spinal cord repair by ameliorating the glial microenvironment. Br J Pharmacol (2012) 0.77
Cancer-associated fibroblasts promote endometrial cancer growth via activation of interleukin-6/STAT-3/c-Myc pathway. Am J Cancer Res (2016) 0.77
Oncostatin M promotes excitotoxicity by inhibiting glutamate uptake in astrocytes: implications in HIV-associated neurotoxicity. J Neuroinflammation (2016) 0.77
A nitric oxide/Ca(2+)/calmodulin/ERK1/2 mitogen-activated protein kinase pathway is involved in the mitogenic effect of IL-1beta in human astrocytoma cells. Br J Pharmacol (2008) 0.76
Multiple pathways in prevention of immune-mediated brain disorders: Implications for the prevention of autism. J Neuroimmunol (2009) 0.76
Meta-type analysis of dopaminergic effects on gene expression in the neuroendocrine brain of female goldfish. Front Endocrinol (Lausanne) (2012) 0.76
Neuron-astrocyte interactions in neurodegenerative diseases: Role of neuroinflammation. Clin Exp Neuroimmunol (2015) 0.76
Lithium Decreases Glial Fibrillary Acidic Protein in a Mouse Model of Alexander Disease. PLoS One (2015) 0.75
MPTP neurotoxicity is highly concordant between the sexes among BXD recombinant inbred mouse strains. Neurotoxicology (2016) 0.75
Lysosomal Storage Diseases-Regulating Neurodegeneration. J Exp Neurosci (2016) 0.75
High salt-induced activation and expression of inflammatory cytokines in cultured astrocytes. Cell Cycle (2017) 0.75
c-Jun N-terminal kinase controls a negative loop in the regulation of glial fibrillary acidic protein expression by retinoic acid. Neuroscience (2012) 0.75
Optic nerve astrocyte reactivity protects function in experimental glaucoma and other nerve injuries. J Exp Med (2017) 0.75
Early inflammatory profiling of schwannoma cells induced by lipopolysaccharide. Histochem Cell Biol (2017) 0.75
Trace amine-associated receptor 1 regulation of methamphetamine-induced neurotoxicity. Neurotoxicology (2017) 0.75
Corticosterone primes the neuroinflammatory response to Gulf War Illness-relevant organophosphates independently of acetylcholinesterase inhibition. J Neurochem (2017) 0.75
GFAP expression in injured astrocytes in rats. Exp Ther Med (2017) 0.75
Time course of the development of Alzheimer-like pathology in the doubly transgenic PS1+APP mouse. Exp Neurol (2002) 1.89
Telomere length, current perceived stress, and urinary stress hormones in women. Cancer Epidemiol Biomarkers Prev (2009) 1.88
Mice deficient in TNF receptors are protected against dopaminergic neurotoxicity: implications for Parkinson's disease. FASEB J (2002) 1.79
Area under the curve and other summary indicators of repeated waking cortisol measurements. Psychosom Med (2007) 1.77
Neuroendocrine aspects of the response to stress. Metabolism (2002) 1.71
Deficiency of TNF receptors suppresses microglial activation and alters the susceptibility of brain regions to MPTP-induced neurotoxicity: role of TNF-alpha. FASEB J (2006) 1.61
Divergent roles for tumor necrosis factor-alpha in the brain. J Neuroimmune Pharmacol (2007) 1.54
Work, obesity, and occupational safety and health. Am J Public Health (2007) 1.53
The Buffalo Cardio-Metabolic Occupational Police Stress (BCOPS) pilot study: methods and participant characteristics. Ann Epidemiol (2005) 1.50
Minocycline attenuates microglial activation but fails to mitigate striatal dopaminergic neurotoxicity: role of tumor necrosis factor-alpha. J Neurochem (2006) 1.49
Distinct roles of PDE4 and PDE10A in the regulation of cAMP/PKA signaling in the striatum. J Neurosci (2008) 1.48
Association of a dietary inflammatory index with inflammatory indices and metabolic syndrome among police officers. J Occup Environ Med (2014) 1.47
Astrogliosis in CNS pathologies: is there a role for microglia? Mol Neurobiol (2010) 1.38
Vacuolar leukoencephalopathy with widespread astrogliosis in mice lacking transcription factor Nrf2. Am J Pathol (2007) 1.31
The spleen contributes to stroke induced neurodegeneration through interferon gamma signaling. Metab Brain Dis (2012) 1.21
Nanotoxicology--a pathologist's perspective. Toxicol Pathol (2010) 1.10
Mechanism of age-dependent susceptibility and novel treatment strategy in glutaric acidemia type I. J Clin Invest (2007) 1.07
Defining "neuroinflammation". Ann N Y Acad Sci (2008) 1.05
Genotoxicity of multi-walled carbon nanotubes at occupationally relevant doses. Part Fibre Toxicol (2014) 1.05
Striatal dysregulation of Cdk5 alters locomotor responses to cocaine, motor learning, and dendritic morphology. Proc Natl Acad Sci U S A (2008) 1.04
Sample-dependent effects on the neuropeptidome detected in rat brain tissue preparations by capillary liquid chromatography with tandem mass spectrometry. Anal Chem (2005) 1.03
A randomized, controlled trial of oxycodone versus placebo in patients with postherpetic neuralgia and painful diabetic neuropathy treated with pregabalin. J Pain (2009) 1.02
Identification and quantification of neuropeptides in brain tissue by capillary liquid chromatography coupled off-line to MALDI-TOF and MALDI-TOF/TOF-MS. Anal Chem (2006) 1.00
Chronic exposure to corticosterone enhances the neuroinflammatory and neurotoxic responses to methamphetamine. J Neurochem (2012) 0.98
Elevated environmental temperature and methamphetamine neurotoxicity. Environ Res (2003) 0.98
Corticosterone primes the neuroinflammatory response to DFP in mice: potential animal model of Gulf War Illness. J Neurochem (2015) 0.96
Shiftwork duration and the awakening cortisol response among police officers. Chronobiol Int (2011) 0.95
Mild steel welding fume causes manganese accumulation and subtle neuroinflammatory changes but not overt neuronal damage in discrete brain regions of rats after short-term inhalation exposure. Neurotoxicology (2009) 0.94
AMP-activated protein kinase phosphorylation in brain is dependent on method of killing and tissue preparation. J Neurochem (2007) 0.93
Low-level human equivalent gestational lead exposure produces supernormal scotopic electroretinograms, increased retinal neurogenesis, and decreased retinal dopamine utilization in rats. Environ Health Perspect (2008) 0.93
Systems analysis of genetic variation in MPTP neurotoxicity in mice. Neurotoxicology (2013) 0.92
Pro-inflammatory interferon gamma signaling is directly associated with stroke induced neurodegeneration. J Neuroimmune Pharmacol (2014) 0.92
Recapitulation of cell signaling events associated with astrogliosis using the brain slice preparation. J Neurochem (2006) 0.92
Do early-life insults contribute to the late-life development of Parkinson and Alzheimer diseases? Metabolism (2008) 0.92
NeuroAIDS, drug abuse, and inflammation: building collaborative research activities. J Neuroimmune Pharmacol (2006) 0.91
Thermoregulation and its influence on toxicity assessment. Toxicology (2007) 0.91
Organophosphates dysregulate dopamine signaling, glutamatergic neurotransmission, and induce neuronal injury markers in striatum. J Neurochem (2011) 0.90
Cortisol patterns and brachial artery reactivity in a high stress environment. Psychiatry Res (2009) 0.89
Depression, cytokines, and glial function. Metabolism (2005) 0.88
Conceptual heuristic models of the interrelationships between obesity and the occupational environment. Scand J Work Environ Health (2013) 0.88
Associations of cortical astrogliosis with cognitive performance and dementia status. J Alzheimers Dis (2004) 0.87
Differential effects of stress on gene transcription factors in catecholaminergic systems. Ann N Y Acad Sci (2004) 0.87
An update on the pharmacological management of post-herpetic neuralgia and painful diabetic neuropathy. CNS Drugs (2008) 0.86
Calcium/calmodulin-dependent protein kinase II activity and expression are altered in the hippocampus of Pb2+-exposed rats. Brain Res (2005) 0.86
Autoantibodies to neurotypic and gliotypic proteins as biomarkers of neurotoxicity: assessment of trimethyltin (TMT). Neurotoxicology (2007) 0.86
Personalized medicine in major depressive disorder -- opportunities and pitfalls. Metabolism (2012) 0.85
Chronic treatment with supraphysiological levels of corticosterone enhances D-MDMA-induced dopaminergic neurotoxicity in the C57BL/6J female mouse. Brain Res (2002) 0.85
Selective changes in gene expression in cortical regions sensitive to amphetamine during the neurodegenerative process. Neurotoxicology (2004) 0.83
Adiposity, muscle, and physical activity: predictors of perturbations in heart rate variability. Am J Hum Biol (2013) 0.83
The pharmacology of wakefulness. Metabolism (2006) 0.83
Spinal glia and chronic pain. Metabolism (2010) 0.82
Associations of long-term shift work with waking salivary cortisol concentration and patterns among police officers. Ind Health (2012) 0.81
Brain concentrations of d-MDMA are increased after stress. Psychopharmacology (Berl) (2004) 0.81
Brain organochlorines and Lewy pathology: the Honolulu-Asia Aging Study. Mov Disord (2012) 0.81
Effects of repeated treatment with phosphodiesterase-4 inhibitors on cAMP signaling, hippocampal cell proliferation, and behavior in the forced-swim test. J Pharmacol Exp Ther (2011) 0.81
Gestational lead exposure selectively decreases retinal dopamine amacrine cells and dopamine content in adult mice. Toxicol Appl Pharmacol (2011) 0.81
d-MDMA during vitamin E deficiency: effects on dopaminergic neurotoxicity and hepatotoxicity. Brain Res (2002) 0.80
Development of an animal model to study the potential neurotoxic effects associated with welding fume inhalation. Neurotoxicology (2006) 0.80
Reproductive experience facilitates recovery from kainic acid-induced neural insult in female Long-Evans rats. Brain Res (2012) 0.79
Neurotoxic esterase: not so toxic? Nat Genet (2003) 0.79
Nerve agent exposure elicits site-specific changes in protein phosphorylation in mouse brain. Brain Res (2010) 0.79
Corticosterone regulates expression of CCL2 in the intact and chemically injured hippocampus. Neurosci Lett (2006) 0.78
Association of the Period3 clock gene length polymorphism with salivary cortisol secretion among police officers. Neuro Endocrinol Lett (2013) 0.78
Leptin, adiponectin, and heart rate variability among police officers. Am J Hum Biol (2014) 0.78
Depressive symptoms and bone mineral density among police officers in a northeastern US City. Glob J Health Sci (2012) 0.78
Indirubins deplete striatal monoamines in the Intact and MPTP-treated mouse brain and block kainate-induced striatal astrogliosis. Neurotoxicol Teratol (2009) 0.78
Time-dependent slowly-reversible inhibition of monoamine oxidase A by N-substituted 1,2,3,6-tetrahydropyridines. Bioorg Med Chem (2011) 0.77
Differential vulnerability of snake species to MPTP: a behavioral and biochemical comparison in ratsnakes (Elaphe) and watersnakes (Nerodia). Neurotoxicol Teratol (2002) 0.77
Functional profile of a novel modulator of serotonin, dopamine, and glutamate neurotransmission. Psychopharmacology (Berl) (2014) 0.77
N-acetylcysteine reverses cardiac myocyte dysfunction in a rodent model of behavioral stress. J Appl Physiol (1985) (2013) 0.76
Regulatory developmental neurotoxicity testing: a model study focussing on conventional neuropathology endpoints and other perspectives. Environ Toxicol Pharmacol (2005) 0.76