|
1
|
A global analysis of cross-talk in a mammalian cellular signalling network.
|
Nat Cell Biol
|
2006
|
2.39
|
|
2
|
Overview of the Alliance for Cellular Signaling.
|
Nature
|
2002
|
2.15
|
|
3
|
Use of a cAMP BRET sensor to characterize a novel regulation of cAMP by the sphingosine 1-phosphate/G13 pathway.
|
J Biol Chem
|
2007
|
1.98
|
|
4
|
Suppression of LPS-induced TNF-alpha production in macrophages by cAMP is mediated by PKA-AKAP95-p105.
|
Sci Signal
|
2009
|
1.85
|
|
5
|
Structure of the p115RhoGEF rgRGS domain-Galpha13/i1 chimera complex suggests convergent evolution of a GTPase activator.
|
Nat Struct Mol Biol
|
2005
|
1.64
|
|
6
|
Mechanisms for reversible regulation between G13 and Rho exchange factors.
|
J Biol Chem
|
2001
|
1.37
|
|
7
|
Thrombin and lysophosphatidic acid receptors utilize distinct rhoGEFs in prostate cancer cells.
|
J Biol Chem
|
2004
|
1.30
|
|
8
|
Activated RhoA binds to the pleckstrin homology (PH) domain of PDZ-RhoGEF, a potential site for autoregulation.
|
J Biol Chem
|
2010
|
1.09
|
|
9
|
Recognition of the activated states of Galpha13 by the rgRGS domain of PDZRhoGEF.
|
Structure
|
2008
|
1.09
|
|
10
|
RhoA binds to the amino terminus of MEKK1 and regulates its kinase activity.
|
J Biol Chem
|
2003
|
1.08
|
|
11
|
Deciphering signaling outcomes from a system of complex networks.
|
Sci Signal
|
2009
|
1.05
|
|
12
|
Modulation of a GEF switch: autoinhibition of the intrinsic guanine nucleotide exchange activity of p115-RhoGEF.
|
Protein Sci
|
2011
|
1.04
|
|
13
|
Mapping the Galpha13 binding interface of the rgRGS domain of p115RhoGEF.
|
J Biol Chem
|
2003
|
1.02
|
|
14
|
Regulation of cAMP responses by the G12/13 pathway converges on adenylyl cyclase VII.
|
J Biol Chem
|
2008
|
0.98
|
|
15
|
Activation of p115-RhoGEF requires direct association of Gα13 and the Dbl homology domain.
|
J Biol Chem
|
2012
|
0.97
|
|
16
|
Activated RhoA is a positive feedback regulator of the Lbc family of Rho guanine nucleotide exchange factor proteins.
|
J Biol Chem
|
2013
|
0.95
|
|
17
|
Signaling and cross-talk by C5a and UDP in macrophages selectively use PLCbeta3 to regulate intracellular free calcium.
|
J Biol Chem
|
2008
|
0.94
|
|
18
|
Distinct roles of adenylyl cyclase VII in regulating the immune responses in mice.
|
J Immunol
|
2010
|
0.93
|
|
19
|
p115 Rho GTPase activating protein interacts with MEKK1.
|
J Cell Physiol
|
2002
|
0.88
|
|
20
|
Functional characterization of p115 RhoGEF.
|
Methods Enzymol
|
2002
|
0.83
|
|
21
|
Zymosan activates protein kinase A via adenylyl cyclase VII to modulate innate immune responses during inflammation.
|
Mol Immunol
|
2012
|
0.83
|
|
22
|
Ribozyme- and siRNA-mediated suppression of RGS-containing RhoGEF proteins.
|
Methods Enzymol
|
2004
|
0.80
|
|
23
|
Assays and characterization of mammalian phosphatidylinositol 4,5-bisphosphate-sensitive phospholipase D.
|
Methods Enzymol
|
2002
|
0.79
|
|
24
|
Modeling species-specific diacylglycerol dynamics in the RAW 264.7 macrophage.
|
J Theor Biol
|
2009
|
0.77
|
|
25
|
Regions on adenylyl cyclase VII required for selective regulation by the G13 pathway.
|
Mol Pharmacol
|
2012
|
0.75
|