Published in Am J Gastroenterol on February 01, 2005
5-aminosalicylic acids and the risk of renal disease: a large British epidemiologic study. Gastroenterology (2004) 1.57
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nat Genet (2010) 17.38
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature (2012) 16.13
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. Nat Genet (2011) 7.98
EGF receptor is required for KRAS-induced pancreatic tumorigenesis. Cancer Cell (2012) 3.19
Canonical Notch2 signaling determines biliary cell fates of embryonic hepatoblasts and adult hepatocytes independent of Hes1. Hepatology (2013) 2.34
Liver-specific inactivation of Notch2, but not Notch1, compromises intrahepatic bile duct development in mice. Hepatology (2008) 2.21
Pancreatic cancer: basic and clinical aspects. Gastroenterology (2005) 2.19
Polymorphisms in melanoma differentiation-associated gene 5 link protein function to clearance of hepatitis C virus. Hepatology (2015) 2.11
Early requirement of Rac1 in a mouse model of pancreatic cancer. Gastroenterology (2011) 1.98
Role of the novel Th17 cytokine IL-17F in inflammatory bowel disease (IBD): upregulated colonic IL-17F expression in active Crohn's disease and analysis of the IL17F p.His161Arg polymorphism in IBD. Inflamm Bowel Dis (2008) 1.96
Novel genetic risk markers for ulcerative colitis in the IL2/IL21 region are in epistasis with IL23R and suggest a common genetic background for ulcerative colitis and celiac disease. Am J Gastroenterol (2009) 1.96
Polymorphisms of the lipopolysaccharide-signaling complex in inflammatory bowel disease: association of a mutation in the Toll-like receptor 4 gene with ulcerative colitis. Clin Immunol (2004) 1.89
Adherence and mental side effects during hepatitis C treatment with interferon alfa and ribavirin in psychiatric risk groups. Hepatology (2003) 1.86
Notch2 is required for progression of pancreatic intraepithelial neoplasia and development of pancreatic ductal adenocarcinoma. Proc Natl Acad Sci U S A (2010) 1.84
Association between variants of PRDM1 and NDP52 and Crohn's disease, based on exome sequencing and functional studies. Gastroenterology (2013) 1.83
Epistasis between Toll-like receptor-9 polymorphisms and variants in NOD2 and IL23R modulates susceptibility to Crohn's disease. Am J Gastroenterol (2009) 1.80
Allele 2 of the interleukin-1 receptor antagonist gene is associated with early gastric cancer. J Clin Oncol (2004) 1.70
Linking genetic susceptibility to Crohn's disease with Th17 cell function: IL-22 serum levels are increased in Crohn's disease and correlate with disease activity and IL23R genotype status. Inflamm Bowel Dis (2008) 1.64
Crohn's disease is associated with a toll-like receptor-9 polymorphism. Gastroenterology (2004) 1.55
rs1004819 is the main disease-associated IL23R variant in German Crohn's disease patients: combined analysis of IL23R, CARD15, and OCTN1/2 variants. PLoS One (2007) 1.48
IKKalpha controls p52/RelB at the skp2 gene promoter to regulate G1- to S-phase progression. EMBO J (2006) 1.43
Chemokine receptor CCR1 but not CCR5 mediates leukocyte recruitment and subsequent renal fibrosis after unilateral ureteral obstruction. J Am Soc Nephrol (2004) 1.41
Genetically engineered mouse models of pancreatic cancer: unravelling tumour biology and progressing translational oncology. Gut (2011) 1.22
Disease activity, ANCA, and IL23R genotype status determine early response to infliximab in patients with ulcerative colitis. Am J Gastroenterol (2010) 1.20
The ATG16L1 gene variants rs2241879 and rs2241880 (T300A) are strongly associated with susceptibility to Crohn's disease in the German population. Am J Gastroenterol (2007) 1.18
Conditional ablation of Notch signaling in pancreatic development. Development (2008) 1.16
ADAM17 regulates epidermal growth factor receptor expression through the activation of Notch1 in non-small cell lung cancer. Cancer Res (2010) 1.14
The contribution of B cells to renal interstitial inflammation. Am J Pathol (2007) 1.14
High-density genotyping study identifies four new susceptibility loci for atopic dermatitis. Nat Genet (2013) 1.11
Altered cell-mediated immunity and increased postoperative infection rate in long-term alcoholic patients. Anesthesiology (2004) 1.09
Prehospital ultrasound in emergency medicine: incidence, feasibility, indications and diagnoses. Eur J Emerg Med (2010) 1.09
The German Chronic Kidney Disease (GCKD) study: design and methods. Nephrol Dial Transplant (2011) 1.09
Vascular endothelial growth factor production and regulation in human peritoneal mesothelial cells. Kidney Int (2002) 1.07
Crohn's disease: an immunodeficiency? Eur J Gastroenterol Hepatol (2003) 1.06
A polymorphism of the NFKBIA gene is associated with Crohn's disease patients lacking a predisposing allele of the CARD15 gene. Int J Colorectal Dis (2003) 1.05
Conditional inactivation of Myc impairs development of the exocrine pancreas. Development (2008) 1.04
Nephrotic-range proteinuria following pamidronate therapy in a patient with metastatic breast cancer: mitochondrial toxicity as a pathogenetic concept? Am J Kidney Dis (2006) 1.03
Lineage fate of ductular reactions in liver injury and carcinogenesis. J Clin Invest (2015) 1.02
Expression and clinicopathological significance of notch signaling and cell-fate genes in biliary tract cancer. Am J Gastroenterol (2011) 0.97
NOD2/CARD15 genotype influences MDP-induced cytokine release and basal IL-12p40 levels in primary isolated peripheral blood monocytes. Inflamm Bowel Dis (2008) 0.97
Identification of epidermal Pdx1 expression discloses different roles of Notch1 and Notch2 in murine Kras(G12D)-induced skin carcinogenesis in vivo. PLoS One (2010) 0.97
Bacterial ghosts as antigen delivery vehicles. Adv Drug Deliv Rev (2005) 0.96
Strong overexpression of CXCR3 axis components in childhood inflammatory bowel disease. Inflamm Bowel Dis (2010) 0.95
The role of insulin and IGF system in pancreatic cancer. J Mol Endocrinol (2013) 0.94
Loss of a renal graft due to recurrence of anti-GBM disease despite rituximab therapy. Clin Transplant (2008) 0.93
Gadolinium as an alternative contrast agent for diagnostic and interventional angiographic procedures in patients with impaired renal function. Nephrol Dial Transplant (2002) 0.93
Polymorphisms of the interleukin-18 gene in periodontitis patients. J Clin Periodontol (2005) 0.92
Cytotoxic and genotoxic effects of resin monomers in human salivary gland tissue and lymphocytes as assessed by the single cell microgel electrophoresis (Comet) assay. Biomaterials (2005) 0.92
Risk factors promoting hypertensive crises: evidence from a longitudinal study. Am J Hypertens (2010) 0.92
Association of polymorphisms in the interleukin-18 gene in patients with Crohn's disease depending on the CARD15/NOD2 genotype. Inflamm Bowel Dis (2005) 0.90
rs224136 on chromosome 10q21.1 and variants in PHOX2B, NCF4, and FAM92B are not major genetic risk factors for susceptibility to Crohn's disease in the German population. Am J Gastroenterol (2009) 0.90
Alterations of the CARD15/NOD2 gene and the impact on management and treatment of Crohn's disease patients. Dig Dis (2003) 0.89
Lipocalin-2 Is a Disease Activity Marker in Inflammatory Bowel Disease Regulated by IL-17A, IL-22, and TNF-α and Modulated by IL23R Genotype Status. Inflamm Bowel Dis (2015) 0.89
The angiotensin I-converting enzyme gene insertion/deletion polymorphism is linked to early gastric cancer. Cancer Epidemiol Biomarkers Prev (2005) 0.88
X-ray phase-contrast CT of a pancreatic ductal adenocarcinoma mouse model. PLoS One (2013) 0.87
Genotype-phenotype analysis of the CXCL16 p.Ala181Val polymorphism in inflammatory bowel disease. Clin Immunol (2008) 0.86
MALDI imaging mass spectrometry for in situ proteomic analysis of preneoplastic lesions in pancreatic cancer. PLoS One (2012) 0.86
Preoperative serum levels of the carcinoembryonic antigen in hereditary non-polyposis colorectal cancer compared to levels in sporadic colorectal cancer. Cancer Detect Prev (2005) 0.86
Tissue inhibitor of metalloproteinases (TIMP)-1 creates a premetastatic niche in the liver through SDF-1/CXCR4-dependent neutrophil recruitment in mice. Hepatology (2014) 0.86
A combined presentation of Graves' disease and Miller-Fisher syndrome. Lancet (2008) 0.85
Novel role of toll-like receptor 3, RIG-I and MDA5 in poly (I:C) RNA-induced mesothelial inflammation. Mol Cell Biochem (2008) 0.85
The presence of fistulas and NOD2 homozygosity strongly predict intestinal stenosis in Crohn's disease independent of the IL23R genotype. J Gastroenterol (2010) 0.85
Bacterial ghosts--biological particles as delivery systems for antigens, nucleic acids and drugs. Curr Opin Biotechnol (2004) 0.85
Effects of mycophenolate mofetil on donor-specific antibody formation in renal transplantation. Clin Transplant (2005) 0.85
Immobilization of plasmid DNA in bacterial ghosts. J Control Release (2005) 0.85
Multimodal molecular imaging of integrin αvβ3 for in vivo detection of pancreatic cancer. J Nucl Med (2014) 0.84
MDR1 gene polymorphism in ulcerative colitis. Gastroenterology (2004) 0.84
KRAS above and beyond - EGFR in pancreatic cancer. Oncotarget (2012) 0.84
Role of the NFKB1 -94ins/delATTG promoter polymorphism in IBD and potential interactions with polymorphisms in the CARD15/NOD2, IKBL, and IL-1RN genes. Inflamm Bowel Dis (2006) 0.83
The 14-bp deletion polymorphism in the HLA-G gene displays significant differences between ulcerative colitis and Crohn's disease and is associated with ileocecal resection in Crohn's disease. Int Immunol (2007) 0.83
Rapid measurement of S-100B serum protein levels by Elecsys S100 immunoassay in patients undergoing carotid artery stenting or endarterectomy. Clin Biochem (2006) 0.83
The LMP7-K allele of the immunoproteasome exhibits reduced transcript stability and predicts high risk of colon cancer. Cancer Res (2011) 0.82
Translational research in pancreatic cancer: KRAS and beyond. Pancreas (2014) 0.82
A polymorphism of the bactericidal/permeability increasing protein (BPI) gene is associated with Crohn's disease. J Clin Gastroenterol (2005) 0.82