PubRank

Henry T Lynch

Author PubWeight™ 237.52‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Revised Bethesda Guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability. J Natl Cancer Inst 2004 14.97
2 Association of risk-reducing surgery in BRCA1 or BRCA2 mutation carriers with cancer risk and mortality. JAMA 2010 8.93
3 Colorectal cancer. Lancet 2010 8.36
4 Prophylactic oophorectomy in carriers of BRCA1 or BRCA2 mutations. N Engl J Med 2002 8.09
5 Long-term effect of aspirin on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trial. Lancet 2011 6.77
6 Prophylactic surgery to reduce the risk of gynecologic cancers in the Lynch syndrome. N Engl J Med 2006 5.70
7 Bilateral prophylactic mastectomy reduces breast cancer risk in BRCA1 and BRCA2 mutation carriers: the PROSE Study Group. J Clin Oncol 2004 5.38
8 BRCAPRO validation, sensitivity of genetic testing of BRCA1/BRCA2, and prevalence of other breast cancer susceptibility genes. J Clin Oncol 2002 4.38
9 Salpingo-oophorectomy and the risk of ovarian, fallopian tube, and peritoneal cancers in women with a BRCA1 or BRCA2 Mutation. JAMA 2006 4.09
10 Contralateral breast cancer in BRCA1 and BRCA2 mutation carriers. J Clin Oncol 2004 3.86
11 Effect of aspirin or resistant starch on colorectal neoplasia in the Lynch syndrome. N Engl J Med 2008 3.76
12 RAD51 135G-->C modifies breast cancer risk among BRCA2 mutation carriers: results from a combined analysis of 19 studies. Am J Hum Genet 2007 3.63
13 Breast cancer risk following bilateral oophorectomy in BRCA1 and BRCA2 mutation carriers: an international case-control study. J Clin Oncol 2005 3.44
14 Common breast cancer-predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers. Am J Hum Genet 2008 3.41
15 Oral contraceptives and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers. J Natl Cancer Inst 2002 3.25
16 Mortality after bilateral salpingo-oophorectomy in BRCA1 and BRCA2 mutation carriers: a prospective cohort study. Lancet Oncol 2006 3.02
17 The risk of extra-colonic, extra-endometrial cancer in the Lynch syndrome. Int J Cancer 2008 2.95
18 Hormone therapy and the risk of breast cancer in BRCA1 mutation carriers. J Natl Cancer Inst 2008 2.78
19 Effect of short-term hormone replacement therapy on breast cancer risk reduction after bilateral prophylactic oophorectomy in BRCA1 and BRCA2 mutation carriers: the PROSE Study Group. J Clin Oncol 2005 2.70
20 Contralateral mastectomy and survival after breast cancer in carriers of BRCA1 and BRCA2 mutations: retrospective analysis. BMJ 2014 2.60
21 Estrogen receptor status in BRCA1- and BRCA2-related breast cancer: the influence of age, grade, and histological type. Clin Cancer Res 2004 2.51
22 AKT proto-oncogene overexpression is an early event during sporadic colon carcinogenesis. Carcinogenesis 2002 2.41
23 Pancreatic cancer genetic epidemiology consortium. Cancer Epidemiol Biomarkers Prev 2006 2.04
24 Common breast cancer susceptibility alleles and the risk of breast cancer for BRCA1 and BRCA2 mutation carriers: implications for risk prediction. Cancer Res 2010 1.90
25 Comparison of extended colectomy and limited resection in patients with Lynch syndrome. Dis Colon Rectum 2010 1.88
26 Molecular analysis of hereditary nonpolyposis colorectal cancer in the United States: high mutation detection rate among clinically selected families and characterization of an American founder genomic deletion of the MSH2 gene. Am J Hum Genet 2003 1.80
27 Altered gene expression in morphologically normal epithelial cells from heterozygous carriers of BRCA1 or BRCA2 mutations. Cancer Prev Res (Phila) 2010 1.80
28 Screening mammography and risk of breast cancer in BRCA1 and BRCA2 mutation carriers: a case-control study. Lancet Oncol 2006 1.79
29 Oophorectomy after menopause and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers. Cancer Epidemiol Biomarkers Prev 2012 1.78
30 Re: Early detection of prostate cancer: AUA guideline: H. B. Carter, P. C. Albertsen, M. J. Barry, R. Etzioni, S. J. Freedland, K. L. Greene, L. Holmberg, P. Kantoff, B. R. Konety, M. H. Murad, D. F. Penson and A. L. Zietman J Urol 2013; 190: 419-426. J Urol 2013 1.75
31 AURKA F31I polymorphism and breast cancer risk in BRCA1 and BRCA2 mutation carriers: a consortium of investigators of modifiers of BRCA1/2 study. Cancer Epidemiol Biomarkers Prev 2007 1.75
32 Advances in counselling and surveillance of patients at risk for pancreatic cancer. Gut 2007 1.68
33 Frequency of premature menopause in women who carry a BRCA1 or BRCA2 mutation. Fertil Steril 2013 1.62
34 The use of preventive measures among healthy women who carry a BRCA1 or BRCA2 mutation. Fam Cancer 2005 1.57
35 What the U.S. Preventive Services Task Force missed in its prostate cancer screening recommendation. Ann Intern Med 2012 1.54
36 Chemotherapy-induced amenorrhea in patients with breast cancer with a BRCA1 or BRCA2 mutation. J Clin Oncol 2013 1.52
37 Intra-abdominal carcinomatosis after prophylactic oophorectomy in women of hereditary breast ovarian cancer syndrome kindreds associated with BRCA1 and BRCA2 mutations. Gynecol Oncol 2005 1.50
38 Effect of pregnancy as a risk factor for breast cancer in BRCA1/BRCA2 mutation carriers. Int J Cancer 2005 1.48
39 Proceedings of the international consensus conference on breast cancer risk, genetics, & risk management, April, 2007. Breast J 2009 1.48
40 Pathologic features of endometrial carcinoma associated with HNPCC: a comparison with sporadic endometrial carcinoma. Cancer 2006 1.47
41 Hereditary diffuse gastric cancer: association with lobular breast cancer. Fam Cancer 2008 1.45
42 Identification of individuals at risk for Lynch syndrome using targeted evaluations and genetic testing: National Society of Genetic Counselors and the Collaborative Group of the Americas on Inherited Colorectal Cancer joint practice guideline. J Genet Couns 2011 1.40
43 MGUS, multiple myeloma, and paratarg-7. Lancet Oncol 2009 1.39
44 Disruption of the expected positive correlation between breast tumor size and lymph node status in BRCA1-related breast carcinoma. Cancer 2003 1.38
45 Two PALB2 germline mutations found in both BRCA1+ and BRCAx familial breast cancer. Breast Cancer Res Treat 2015 1.37
46 Proceedings of the international consensus conference on breast cancer risk, genetics, & risk management, April, 2007. Cancer 2008 1.28
47 The risk of ovarian cancer after breast cancer in BRCA1 and BRCA2 carriers. Gynecol Oncol 2005 1.27
48 A comparison of bilateral breast cancers in BRCA carriers. Cancer Epidemiol Biomarkers Prev 2005 1.27
49 Cancer variation associated with the position of the mutation in the BRCA2 gene. Fam Cancer 2004 1.25
50 Evaluation of linkage of breast cancer to the putative BRCA3 locus on chromosome 13q21 in 128 multiple case families from the Breast Cancer Linkage Consortium. Proc Natl Acad Sci U S A 2002 1.23
51 Molecular screening for the Lynch syndrome--better than family history? N Engl J Med 2005 1.22
52 Common breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2. Breast Cancer Res 2011 1.22
53 Family history of cancer and cancer risks in women with BRCA1 or BRCA2 mutations. J Natl Cancer Inst 2010 1.21
54 Age at menarche and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers. Cancer Causes Control 2005 1.20
55 MYC is amplified in BRCA1-associated breast cancers. Clin Cancer Res 2004 1.18
56 Common variants at the 19p13.1 and ZNF365 loci are associated with ER subtypes of breast cancer and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers. Cancer Epidemiol Biomarkers Prev 2012 1.17
57 TGFBR1*6A may contribute to hereditary colorectal cancer. J Clin Oncol 2005 1.16
58 Should all BRCA1 mutation carriers with stage I breast cancer receive chemotherapy? Breast Cancer Res Treat 2013 1.16
59 The risk of endometrial cancer in women with BRCA1 and BRCA2 mutations. A prospective study. Gynecol Oncol 2006 1.14
60 Current hypotheses on how microsatellite instability leads to enhanced survival of Lynch Syndrome patients. Clin Dev Immunol 2010 1.12
61 Tobacco use and increased colorectal cancer risk in patients with hereditary nonpolyposis colorectal cancer (Lynch syndrome). Arch Intern Med 2004 1.10
62 Whole exome sequencing suggests much of non-BRCA1/BRCA2 familial breast cancer is due to moderate and low penetrance susceptibility alleles. PLoS One 2013 1.10
63 Breastfeeding and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers. Breast Cancer Res 2012 1.10
64 Suspected HNPCC and Amsterdam criteria II: evaluation of mutation detection rate, an international collaborative study. Int J Colorectal Dis 2002 1.09
65 Origins and prevalence of the American Founder Mutation of MSH2. Cancer Res 2008 1.06
66 Age-dependent morphological alterations of human ovaries from populations with and without BRCA mutations. Gynecol Oncol 2006 1.06
67 The risk of breast cancer in women with a BRCA1 mutation from North America and Poland. Int J Cancer 2011 1.06
68 Modification of BRCA1-Associated Breast and Ovarian Cancer Risk by BRCA1-Interacting Genes. Cancer Res 2011 1.05
69 Genetic variation in insulin-like growth factor signaling genes and breast cancer risk among BRCA1 and BRCA2 carriers. Breast Cancer Res 2009 1.04
70 Hereditary nonpolyposis colorectal cancer: preventive management. Cancer Treat Rev 2003 1.02
71 Spontaneous and therapeutic abortions and the risk of breast cancer among BRCA mutation carriers. Breast Cancer Res 2006 1.01
72 Bilateral prophylactic oophorectomy and bilateral prophylactic mastectomy in a prospective cohort of unaffected BRCA1 and BRCA2 mutation carriers. Clin Breast Cancer 2007 1.01
73 Modification of ovarian cancer risk by BRCA1/2-interacting genes in a multicenter cohort of BRCA1/2 mutation carriers. Cancer Res 2009 1.01
74 Pathogenicity of the hereditary colorectal cancer mutation hMLH1 del616 linked to shortage of the functional protein. Gastroenterology 2003 0.99
75 Screening adherence in BRCA1/2 families is associated with primary physicians' behavior. Am J Med Genet A 2004 0.99
76 The incidence of endometrial cancer in women with BRCA1 and BRCA2 mutations: an international prospective cohort study. Gynecol Oncol 2013 0.98
77 Lymphocyte recruitment into the tumor site is altered in patients with MSI-H colon cancer. Fam Cancer 2009 0.98
78 The CYP1A2 genotype modifies the association between coffee consumption and breast cancer risk among BRCA1 mutation carriers. Cancer Epidemiol Biomarkers Prev 2007 0.98
79 Hereditary colorectal cancer-part II. Curr Probl Surg 2005 0.98
80 Analysis of CHEK2 gene for ovarian cancer susceptibility. Gynecol Oncol 2004 0.97
81 Neuroendocrine-type prostatic adenocarcinoma with microsatellite instability in a patient with lynch syndrome. Int J Surg Pathol 2010 0.97
82 Understanding the development of human bladder cancer by using a whole-organ genomic mapping strategy. Lab Invest 2008 0.96
83 Hereditary colon cancer--part I. Curr Probl Surg 2005 0.96
84 Toward a consensus in molecular diagnosis of hereditary nonpolyposis colorectal cancer (Lynch syndrome). J Natl Cancer Inst 2007 0.95
85 Infertility, treatment of infertility, and the risk of breast cancer among women with BRCA1 and BRCA2 mutations: a case-control study. Cancer Causes Control 2008 0.95
86 Changes in body weight and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers. Breast Cancer Res 2005 0.95
87 The history of Lynch syndrome. Fam Cancer 2013 0.94
88 The joint effect of smoking and AIB1 on breast cancer risk in BRCA1 mutation carriers. Carcinogenesis 2005 0.94
89 Loss of surface and cyst epithelial basement membranes and preneoplastic morphologic changes in prophylactic oophorectomies. Cancer 2003 0.94
90 Occult ovarian cancers identified at risk-reducing salpingo-oophorectomy in a prospective cohort of BRCA1/2 mutation carriers. Breast Cancer Res Treat 2010 0.93
91 Alcohol and tobacco lower the age of presentation in sporadic pancreatic cancer in a dose-dependent manner: a multicenter study. Am J Gastroenterol 2012 0.93
92 Timing of oral contraceptive use and the risk of breast cancer in BRCA1 mutation carriers. Breast Cancer Res Treat 2014 0.93
93 PCCR: Pancreatic Cancer Collaborative Registry. Cancer Inform 2011 0.92
94 Risk of ipsilateral breast cancer in BRCA1 and BRCA2 mutation carriers. Breast Cancer Res Treat 2011 0.92
95 Hereditary pancreatic cancer: a clinical perspective. Best Pract Res Clin Gastroenterol 2009 0.92
96 Hormone replacement therapy and the risk of ovarian cancer in BRCA1 and BRCA2 mutation carriers. Gynecol Oncol 2005 0.91
97 Breast and ovarian cancer risk and risk reduction in Jewish BRCA1/2 mutation carriers. J Clin Oncol 2012 0.91
98 Breast cancer risk in BRCA1 and BRCA2 mutation carriers and polyglutamine repeat length in the AIB1 gene. Int J Cancer 2005 0.91
99 Risk of colon cancer in hereditary non-polyposis colorectal cancer patients as predicted by fuzzy modeling: Influence of smoking. World J Gastroenterol 2006 0.91
100 Hereditary breast cancer: part II. Management of hereditary breast cancer: implications of molecular genetics and pathology. Breast J 2007 0.89
101 Characterization of the neoplastic phenotype in the familial atypical multiple-mole melanoma-pancreatic carcinoma syndrome. Cancer 2003 0.89
102 Inherited, familial and sporadic primary open-angle glaucoma. J Natl Med Assoc 2007 0.89
103 Prevalence of Barrett esophagus in first-degree relatives of patients with esophageal adenocarcinoma. J Clin Gastroenterol 2011 0.89
104 History and molecular genetics of Lynch syndrome in family G: a century later. JAMA 2005 0.88
105 Age at first birth and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers. Breast Cancer Res Treat 2007 0.88
106 Serrated polyposis: the last (or only the latest?) frontier of familial polyposis? Am J Gastroenterol 2012 0.87
107 BRCA1 and BRCA2 families and the risk of skin cancer. Fam Cancer 2010 0.86
108 Common BRCA2 variants and modification of breast and ovarian cancer risk in BRCA1 mutation carriers. Cancer Epidemiol Biomarkers Prev 2005 0.86
109 BRCA1 and BRCA2 mutations in breast and ovarian cancer syndrome: reflection on the Creighton University historical series of high risk families. Fam Cancer 2006 0.86
110 Familial adenomatous polyposis in children younger than age ten years: a multidisciplinary clinic experience. Dis Colon Rectum 2007 0.85
111 Brain tumors in individuals with familial adenomatous polyposis: a cancer registry experience and pooled case report analysis. Cancer 2007 0.85
112 Cancer family history and genetic testing: are malpractice adjudications waiting to happen? Am J Gastroenterol 2002 0.85
113 Genetic counseling and the advanced practice oncology nursing role in a hereditary cancer prevention clinic: hereditary breast cancer focus (part I). Breast J 2009 0.85
114 Identification of high-risk pancreatic cancer-prone families. Gastroenterol Clin North Am 2004 0.85
115 Genetic variation in IGF2 and HTRA1 and breast cancer risk among BRCA1 and BRCA2 carriers. Cancer Epidemiol Biomarkers Prev 2011 0.84
116 Familial B-cell chronic lymphocytic leukemia: analysis of cytogenetic abnormalities, immunophenotypic profiles, and immunoglobulin heavy chain gene usage. Am J Clin Pathol 2007 0.84
117 Efficient molecular screening of Lynch syndrome by specific 3' promoter methylation of the MLH1 or BRAF mutation in colorectal cancer with high-frequency microsatellite instability. Oncol Rep 2009 0.83
118 Population differences in familial adenomatous polyposis may be an expression of geographic differences in APC mutation pattern. Cancer Genet Cytogenet 2007 0.83
119 Altered transcriptome signature of phenotypically normal skin fibroblasts heterozygous for CDKN2A in familial melanoma: relevance to early intervention. Oncotarget 2013 0.83
120 Genotype/phenotype of familial pancreatic cancer. Endocrinol Metab Clin North Am 2006 0.83
121 The impact of pregnancy on breast cancer survival in women who carry a BRCA1 or BRCA2 mutation. Breast Cancer Res Treat 2013 0.82
122 Immunology and the Lynch syndrome. Gastroenterology 2008 0.82
123 Sex hormone regulation of survivin gene expression. J Endocrinol 2010 0.82
124 Upper urinary tract carcinoma in Lynch syndrome cases. J Urol 2011 0.82
125 CHEK2 mutation and hereditary breast cancer. J Clin Oncol 2006 0.82
126 Use of risk-reducing surgeries in a prospective cohort of 1,499 BRCA1 and BRCA2 mutation carriers. Breast Cancer Res Treat 2014 0.81
127 Risk factors for endometrial cancer among women with a BRCA1 or BRCA2 mutation: a case control study. Fam Cancer 2015 0.81
128 Hereditary nonpolyposis colorectal cancer (Lynch Syndrome) in Argentina: report from a referral hospital register. Dis Colon Rectum 2007 0.81
129 Genetic factors and colorectal cancer in Ashkenazi Jews. Fam Cancer 2004 0.80
130 Linkage analysis of chromosome 4 in families with familial pancreatic cancer. Cancer Biol Ther 2007 0.80
131 Tamoxifen and the risk of ovarian cancer in BRCA1 mutation carriers. Gynecol Oncol 2009 0.80
132 Alcohol consumption and the risk of breast cancer among BRCA1 and BRCA2 mutation carriers. Breast 2010 0.80
133 BRCA1 wild-type allele modifies risk of ovarian cancer in carriers of BRCA1 germ-line mutations. Cancer Epidemiol Biomarkers Prev 2003 0.79
134 Immunoassay for wild-type protein in lymphocytes predicts germline mutations in patients at risk for hereditary colorectal cancer. J Lab Clin Med 2004 0.79
135 Mammography screening and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers: a prospective study. Breast Cancer Res Treat 2014 0.79
136 Duration of tamoxifen use and the risk of contralateral breast cancer in BRCA1 and BRCA2 mutation carriers. Breast Cancer Res Treat 2014 0.79
137 Detecting BRCA2 protein truncation in tissue biopsies to identify breast cancers that arise in BRCA2 gene mutation carriers. J Clin Oncol 2009 0.78
138 Familial prostate cancer and HOXB13 founder mutations: geographic and racial/ethnic variations. Hum Genet 2012 0.78
139 Phenotypic heterogeneity of hereditary gynecologic cancers: a report from the Creighton hereditary cancer registry. Fam Cancer 2013 0.78
140 The I1307K APC polymorphism in Ashkenazi Jews with colorectal cancer: clinical and pathologic features. Cancer Genet Cytogenet 2006 0.77
141 Barrett's esophagus in the patients with familial adenomatous polyposis. Fam Cancer 2014 0.77
142 International rates of breast reconstruction after prophylactic mastectomy in BRCA1 and BRCA2 mutation carriers. Ann Surg Oncol 2013 0.77
143 Excess of extracolonic non-endometrial multiple primary cancers in MSH2 germline mutation carriers over MLH1. J Surg Oncol 2013 0.77
144 Sessile serrated adenomas: why conventional endoscopy is okay for unconventional polyps. Dig Dis Sci 2014 0.76
145 Anthropometric measures and risk of ovarian cancer among BRCA1 and BRCA2 mutation carriers. Obesity (Silver Spring) 2012 0.76
146 Does the age of breast cancer diagnosis in first-degree relatives impact on the risk of breast cancer in BRCA1 and BRCA2 mutation carriers? Breast Cancer Res Treat 2015 0.76
147 The importance of functional testing in the genetic assessment of Muir-Torre syndrome, a clinical subphenotype of HNPCC. Int J Oncol 2006 0.76
148 Endometrial cancers in mutation carriers from hereditary breast ovarian cancer syndrome kindreds: report from the Creighton University Hereditary Cancer Registry with review of the implications. Int J Gynecol Cancer 2015 0.76
149 Quality indicators for colonoscopy and the risk of interval cancer. N Engl J Med 2010 0.75
150 Stemming the tide of cancer for BRCA1/2 mutation carriers. J Clin Oncol 2008 0.75
151 Commentary on 'Colonoscopy screening compliance and outcomes in patients with Lynch syndrome'. Colorectal Dis 2015 0.75
152 Effect of Prior Bilateral Oophorectomy on the Presentation of Breast Cancer in BRCA1 and BRCA2 Mutation Carriers. Hered Cancer Clin Pract 2005 0.75
153 Colorectal cancer survival advantage in MUTYH-associated polyposis and Lynch syndrome families. J Natl Cancer Inst 2010 0.75
154 Familial Cancer. Foreword. Fam Cancer 2007 0.75
155 How early to test for a cancer-causing germline mutation. Cancer Genet Cytogenet 2008 0.75
156 Cigarette smoking and breast cancer risk: limited evidence of genotypic and exogenous carcinogenic factors and their interactions. Breast J 2010 0.75
157 Mutations in the Histone Modifier PRDM6 Are Associated with Isolated Nonsyndromic Patent Ductus Arteriosus. Am J Hum Genet 2016 0.75
158 Thirty-nine-year-old with familial colon cancer, and variant of undetermined significance in MSH6. Semin Oncol 2012 0.75
159 Three new mutations in hereditary nonpolyposis colorectal cancer (Lynch syndrome II) in Uruguay. Cancer Genet Cytogenet 2003 0.75
160 Prospective evaluation of alcohol consumption and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers. Breast Cancer Res Treat 2015 0.75