Published in J Cell Sci on January 25, 2005
FoxM1 promotes β-catenin nuclear localization and controls Wnt target-gene expression and glioma tumorigenesis. Cancer Cell (2011) 3.58
Thiazole antibiotics target FoxM1 and induce apoptosis in human cancer cells. PLoS One (2009) 2.82
Forkhead box proteins: tuning forks for transcriptional harmony. Nat Rev Cancer (2013) 2.02
Deletion of Forkhead Box M1 transcription factor from respiratory epithelial cells inhibits pulmonary tumorigenesis. PLoS One (2009) 1.93
Activation of FoxM1 during G2 requires cyclin A/Cdk-dependent relief of autorepression by the FoxM1 N-terminal domain. Mol Cell Biol (2008) 1.67
Forkhead box M1 transcription factor: a novel target for cancer therapy. Cancer Treat Rev (2009) 1.63
Cross species genomic analysis identifies a mouse model as undifferentiated pleomorphic sarcoma/malignant fibrous histiocytoma. PLoS One (2009) 1.40
SRp20 is a proto-oncogene critical for cell proliferation and tumor induction and maintenance. Int J Biol Sci (2010) 1.40
FOXD3 is a mutant B-RAF-regulated inhibitor of G(1)-S progression in melanoma cells. Cancer Res (2010) 1.39
FOXM1 is a transcriptional target of ERalpha and has a critical role in breast cancer endocrine sensitivity and resistance. Oncogene (2010) 1.34
Induction of human epithelial stem/progenitor expansion by FOXM1. Cancer Res (2010) 1.27
FoxM1 is up-regulated by obesity and stimulates beta-cell proliferation. Mol Endocrinol (2010) 1.23
FoxM1c counteracts oxidative stress-induced senescence and stimulates Bmi-1 expression. J Biol Chem (2008) 1.19
Aberrant activation of ERK/FOXM1 signaling cascade triggers the cell migration/invasion in ovarian cancer cells. PLoS One (2011) 1.11
SUMOylation inhibits FOXM1 activity and delays mitotic transition. Oncogene (2013) 1.09
Aurora B is regulated by the mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/ERK) signaling pathway and is a valuable potential target in melanoma cells. J Biol Chem (2012) 1.03
Foxm1 mediates cross talk between Kras/mitogen-activated protein kinase and canonical Wnt pathways during development of respiratory epithelium. Mol Cell Biol (2012) 0.99
Increased expression of FoxM1 transcription factor in respiratory epithelium inhibits lung sacculation and causes Clara cell hyperplasia. Dev Biol (2010) 0.99
Peroxiredoxin 3 is a redox-dependent target of thiostrepton in malignant mesothelioma cells. PLoS One (2012) 0.99
High Fat Diet Regulation of β-Cell Proliferation and β-Cell Mass. Open Endocrinol J (2010) 0.99
The p38 MAPK-MK2 axis regulates E2F1 and FOXM1 expression after epirubicin treatment. Mol Cancer Res (2012) 0.98
Dual blockade of the Hedgehog and ERK1/2 pathways coordinately decreases proliferation and survival of cholangiocarcinoma cells. J Cancer Res Clin Oncol (2006) 0.98
Foxm1 expression in prostate epithelial cells is essential for prostate carcinogenesis. J Biol Chem (2013) 0.96
Cytoplasmic Forkhead box M1 (FoxM1) in esophageal squamous cell carcinoma significantly correlates with pathological disease stage. World J Surg (2012) 0.94
Forkhead box M1 (FoxM1) gene is a new STAT3 transcriptional factor target and is essential for proliferation, survival and DNA repair of K562 cell line. PLoS One (2012) 0.93
AKT signaling mediates IGF-I survival actions on otic neural progenitors. PLoS One (2012) 0.92
Extracellular signal-regulated kinase 1/2 activity is not required in mammalian cells during late G2 for timely entry into or exit from mitosis. Mol Biol Cell (2006) 0.92
FOXM1b, which is present at elevated levels in cancer cells, has a greater transforming potential than FOXM1c. Front Oncol (2013) 0.91
Identification of a phosphorylation-dependent nuclear localization motif in interferon regulatory factor 2 binding protein 2. PLoS One (2011) 0.91
FOXM1 and its oncogenic signaling in pancreatic cancer pathogenesis. Biochim Biophys Acta (2014) 0.88
Mitochondrial-targeted nitroxides disrupt mitochondrial architecture and inhibit expression of peroxiredoxin 3 and FOXM1 in malignant mesothelioma cells. J Cell Physiol (2013) 0.86
Insights into a Critical Role of the FOXO3a-FOXM1 Axis in DNA Damage Response and Genotoxic Drug Resistance. Curr Drug Targets (2016) 0.84
Targeting of mutant p53-induced FoxM1 with thiostrepton induces cytotoxicity and enhances carboplatin sensitivity in cancer cells. Oncotarget (2014) 0.84
The transcription factor Foxm1 is essential for the quiescence and maintenance of hematopoietic stem cells. Nat Immunol (2015) 0.83
Activated FoxM1 attenuates streptozotocin-mediated β-cell death. Mol Endocrinol (2014) 0.83
Calumenin-15 facilitates filopodia formation by promoting TGF-β superfamily cytokine GDF-15 transcription. Cell Death Dis (2013) 0.83
Genetic determinants of FOXM1 overexpression in epithelial ovarian cancer and functional contribution to cell cycle progression. Oncotarget (2015) 0.83
Lipid overloading during liver regeneration causes delayed hepatocyte DNA replication by increasing ER stress in mice with simple hepatic steatosis. J Gastroenterol (2013) 0.82
Identification of lung-cancer-related genes with the shortest path approach in a protein-protein interaction network. Biomed Res Int (2013) 0.82
Polo-like kinase 1-mediated phosphorylation of Forkhead box protein M1b antagonizes its SUMOylation and facilitates its mitotic function. J Biol Chem (2014) 0.81
Novel interactions between FOXM1 and CDC25A regulate the cell cycle. PLoS One (2012) 0.81
Control of regional decidualization in implantation: Role of FoxM1 downstream of Hoxa10 and cyclin D3. Sci Rep (2015) 0.81
Targeted inhibition of metastatic melanoma through interference with Pin1-FOXM1 signaling. Oncogene (2015) 0.81
The EGF receptor ligand amphiregulin controls cell division via FoxM1. Oncogene (2015) 0.80
FOXM1 binds directly to non-consensus sequences in the human genome. Genome Biol (2015) 0.80
FOXM1 in sarcoma: role in cell cycle, pluripotency genes and stem cell pathways. Oncotarget (2016) 0.79
The Role of Forkhead Box Protein M1 in Breast Cancer Progression and Resistance to Therapy. Int J Breast Cancer (2016) 0.79
Transcription factor interactions mediate EGF-dependent COX-2 expression. Mol Cancer Res (2013) 0.79
Investigation of FOXM1 as a Potential New Target for Melanoma. PLoS One (2015) 0.79
Prognostic Value of FOXM1 in Patients with Malignant Solid Tumor: A Meta-Analysis and System Review. Dis Markers (2015) 0.78
Formation of Tankyrase Inhibitor-Induced Degradasomes Requires Proteasome Activity. PLoS One (2016) 0.77
Wild type N-ras displays anti-malignant properties, in part by downregulating decorin. J Cell Physiol (2012) 0.77
Identification of Glypican-3 as a potential metastasis suppressor gene in gastric cancer. Oncotarget (2016) 0.76
O-GlcNAcylation regulates breast cancer metastasis via SIRT1 modulation of FOXM1 pathway. Oncogene (2016) 0.76
A novel FOXM1 isoform, FOXM1D, promotes epithelial-mesenchymal transition and metastasis through ROCKs activation in colorectal cancer. Oncogene (2016) 0.76
Activation of FoxM1 Revitalizes the Replicative Potential of Aged β-Cells in Male Mice and Enhances Insulin Secretion. Diabetes (2015) 0.76
FOXM1 regulates proliferation, senescence and oxidative stress in keratinocytes and cancer cells. Aging (Albany NY) (2016) 0.75
Targeting GLI by GANT61 involves mechanisms dependent on inhibition of both transcription and DNA licensing. Oncotarget (2016) 0.75
β-catenin and Kras/Foxm1 signaling pathway are critical to restrict Sox9 in basal cells during pulmonary branching morphogenesis. Dev Dyn (2016) 0.75
Raf Kinases are Essential for Phosphate Induction of Erk1/2 Phosphorylation in Hypertrophic Chondrocytes and Normal Endochondral Bone Development. J Biol Chem (2017) 0.75
Acetylation of FOXM1 is essential for its transactivation and tumor growth stimulation. Oncotarget (2016) 0.75
Genome-wide analysis of gynecologic cancer: The Cancer Genome Atlas in ovarian and endometrial cancer. Oncol Lett (2017) 0.75
The Forkhead box M1 protein regulates the transcription of the estrogen receptor alpha in breast cancer cells. J Biol Chem (2006) 1.68
Loss of MKP3 mediated by oxidative stress enhances tumorigenicity and chemoresistance of ovarian cancer cells. Carcinogenesis (2008) 1.49
FoxM1c counteracts oxidative stress-induced senescence and stimulates Bmi-1 expression. J Biol Chem (2008) 1.19
Raf/MEK/MAPK signaling stimulates the nuclear translocation and transactivating activity of FOXM1. Methods Mol Biol (2010) 0.97
Activation of AMPK inhibits cervical cancer cell growth through AKT/FOXO3a/FOXM1 signaling cascade. BMC Cancer (2013) 0.96
A 3D collagen microsphere culture system for GDNF-secreting HEK293 cells with enhanced protein productivity. Biomaterials (2007) 0.94
Targeted inactivation of kinesin-1 in pancreatic β-cells in vivo leads to insulin secretory deficiency. Diabetes (2010) 0.93
Enhanced normal short-term human myelopoiesis in mice engineered to express human-specific myeloid growth factors. Blood (2012) 0.93
FOXM1b, which is present at elevated levels in cancer cells, has a greater transforming potential than FOXM1c. Front Oncol (2013) 0.91
Identification and characterization of human VCY2-interacting protein: VCY2IP-1, a microtubule-associated protein-like protein. Biol Reprod (2003) 0.91
A multi PDZ-domain protein Pdzd2 contributes to functional expression of sensory neuron-specific sodium channel Na(V)1.8. Mol Cell Neurosci (2009) 0.89
Identification of cis-elements for ethylene and circadian regulation of the Solanum melongena gene encoding cysteine proteinase. Plant Mol Biol (2005) 0.89
Proteolytic cleavage of PDZD2 generates a secreted peptide containing two PDZ domains. EMBO Rep (2003) 0.88
Correlated evolution of transcription factors and their binding sites. Bioinformatics (2011) 0.87
Signaling mechanisms of melatonin in antiproliferation of hormone-refractory 22Rv1 human prostate cancer cells: implications for prostate cancer chemoprevention. J Pineal Res (2007) 0.84
Reduced expression of AMPK-β1 during tumor progression enhances the oncogenic capacity of advanced ovarian cancer. Mol Cancer (2014) 0.84
Melatonin as a negative mitogenic hormonal regulator of human prostate epithelial cell growth: potential mechanisms and clinical significance. J Pineal Res (2008) 0.84
VCY2 protein interacts with the HECT domain of ubiquitin-protein ligase E3A. Biochem Biophys Res Commun (2002) 0.84
The coactivator Bridge-1 increases transcriptional activation by pancreas duodenum homeobox-1 (PDX-1). Mol Cell Endocrinol (2005) 0.83
Interactions with p300 enhance transcriptional activation by the PDZ-domain coactivator Bridge-1. J Endocrinol (2005) 0.83
The autocrine human secreted PDZ domain-containing protein 2 (sPDZD2) induces senescence or quiescence of prostate, breast and liver cancer cells via transcriptional activation of p53. Cancer Lett (2008) 0.82
G-box binding coincides with increased Solanum melongena cysteine proteinase expression in senescent fruits and circadian-regulated leaves. Plant Mol Biol (2003) 0.80
Signal transduction of receptor-mediated antiproliferative action of melatonin on human prostate epithelial cells involves dual activation of Gα(s) and Gα(q) proteins. J Pineal Res (2010) 0.79
The roles of the PDZ-containing proteins bridge-1 and PDZD2 in the regulation of insulin production and pancreatic beta-cell mass. Curr Protein Pept Sci (2009) 0.78
Secreted PDZD2 exerts concentration-dependent effects on the proliferation of INS-1E cells. Int J Biochem Cell Biol (2005) 0.76
Differential NOD/SCID mouse engraftment of peripheral blood CD34+ cells and JAK2V617F clones from patients with myeloproliferative neoplasms. Leuk Res (2010) 0.75