Published in Curr Drug Targets on January 01, 2016
Foxo3 activity promoted by non-coding effects of circular RNA and Foxo3 pseudogene in the inhibition of tumor growth and angiogenesis. Oncogene (2015) 1.09
Ergosterol purified from medicinal mushroom Amauroderma rude inhibits cancer growth in vitro and in vivo by up-regulating multiple tumor suppressors. Oncotarget (2015) 0.93
FOXM1: A novel drug target in gastroenteropancreatic neuroendocrine tumors. Oncotarget (2015) 0.81
Multiplicity of acquired cross-resistance in paclitaxel-resistant cancer cells is associated with feedback control of TUBB3 via FOXO3a-mediated ABCB1 regulation. Oncotarget (2016) 0.80
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BRCA1 positively regulates FOXO3 expression by restricting FOXO3 gene methylation and epigenetic silencing through targeting EZH2 in breast cancer. Oncogenesis (2016) 0.75
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Unified nomenclature for the winged helix/forkhead transcription factors. Genes Dev (2000) 5.36
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DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein. Science (2002) 4.88
Cell cycle and death control: long live Forkheads. Trends Biochem Sci (2002) 4.87
Forkhead box M1 regulates the transcriptional network of genes essential for mitotic progression and genes encoding the SCF (Skp2-Cks1) ubiquitin ligase. Mol Cell Biol (2005) 4.80
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Regulation of DNA cross-link repair by the Fanconi anemia/BRCA pathway. Genes Dev (2012) 3.42
FoxO3a transcriptional regulation of Bim controls apoptosis in paclitaxel-treated breast cancer cell lines. J Biol Chem (2003) 3.41
FoxM1B is overexpressed in human glioblastomas and critically regulates the tumorigenicity of glioma cells. Cancer Res (2006) 3.28
Loss of the forkhead transcription factor FoxM1 causes centrosome amplification and mitotic catastrophe. Cancer Res (2005) 3.23
Cell cycle inhibition by FoxO forkhead transcription factors involves downregulation of cyclin D. Mol Cell Biol (2002) 3.20
Identification and validation of commonly overexpressed genes in solid tumors by comparison of microarray data. Neoplasia (2005) 3.16
The Forkhead Box m1b transcription factor is essential for hepatocyte DNA replication and mitosis during mouse liver regeneration. Proc Natl Acad Sci U S A (2002) 2.93
Increased levels of the FoxM1 transcription factor accelerate development and progression of prostate carcinomas in both TRAMP and LADY transgenic mice. Cancer Res (2006) 2.92
A model of acquired autoresistance to a potent ErbB2 tyrosine kinase inhibitor and a therapeutic strategy to prevent its onset in breast cancer. Proc Natl Acad Sci U S A (2006) 2.86
The Forkhead Box m1 transcription factor stimulates the proliferation of tumor cells during development of lung cancer. Cancer Res (2006) 2.84
Control of cell cycle exit and entry by protein kinase B-regulated forkhead transcription factors. Mol Cell Biol (2002) 2.84
FOXM1 is a downstream target of Gli1 in basal cell carcinomas. Cancer Res (2002) 2.71
Down-regulation of Forkhead Box M1 transcription factor leads to the inhibition of invasion and angiogenesis of pancreatic cancer cells. Cancer Res (2007) 2.71
Defective DNA repair and neurodegenerative disease. Cell (2007) 2.57
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Forkhead transcription factors contribute to execution of the mitotic programme in mammals. Nature (2001) 2.43
FoxM1 is a general target for proteasome inhibitors. PLoS One (2009) 2.34
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Thiostrepton selectively targets breast cancer cells through inhibition of forkhead box M1 expression. Mol Cancer Ther (2008) 2.18
The MK5/PRAK kinase and Myc form a negative feedback loop that is disrupted during colorectal tumorigenesis. Mol Cell (2011) 2.17
SIRT inhibitors induce cell death and p53 acetylation through targeting both SIRT1 and SIRT2. Mol Cancer Ther (2010) 2.15
Paclitaxel-induced nuclear translocation of FOXO3a in breast cancer cells is mediated by c-Jun NH2-terminal kinase and Akt. Cancer Res (2006) 2.13
Premature expression of the winged helix transcription factor HFH-11B in regenerating mouse liver accelerates hepatocyte entry into S phase. Mol Cell Biol (1999) 2.11
Chk2 mediates stabilization of the FoxM1 transcription factor to stimulate expression of DNA repair genes. Mol Cell Biol (2006) 2.11
Two-step activation of ATM by DNA and the Mre11-Rad50-Nbs1 complex. Nat Struct Mol Biol (2006) 2.09
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Forkhead box proteins: tuning forks for transcriptional harmony. Nat Rev Cancer (2013) 2.02
The forkhead box M1 transcription factor contributes to the development and growth of mouse colorectal cancer. Gastroenterology (2007) 1.99
Human MUC1 carcinoma antigen regulates intracellular oxidant levels and the apoptotic response to oxidative stress. J Biol Chem (2003) 1.98
DNA damage tumor suppressor genes and genomic instability. Curr Opin Genet Dev (2004) 1.94
The MuvB complex sequentially recruits B-Myb and FoxM1 to promote mitotic gene expression. Genes Dev (2012) 1.92
Applications of post-translational modifications of FoxO family proteins in biological functions. J Mol Cell Biol (2011) 1.90
Cyclin G2 associates with protein phosphatase 2A catalytic and regulatory B' subunits in active complexes and induces nuclear aberrations and a G1/S phase cell cycle arrest. J Biol Chem (2002) 1.90
Inhibition of the phosphoinositide 3-kinase pathway induces a senescence-like arrest mediated by p27Kip1. J Biol Chem (2000) 1.88
The FANCJ/MutLalpha interaction is required for correction of the cross-link response in FA-J cells. EMBO J (2007) 1.86
Local action of the chromatin assembly factor CAF-1 at sites of nucleotide excision repair in vivo. EMBO J (2003) 1.85
Raf/MEK/MAPK signaling stimulates the nuclear translocation and transactivating activity of FOXM1c. J Cell Sci (2005) 1.85
The transcription factor FOXM1 is a cellular target of the natural product thiostrepton. Nat Chem (2011) 1.82
Role of the retinoblastoma protein family, pRB, p107 and p130 in the negative control of cell growth. Oncogene (1998) 1.82
Multiple roles of FOXO transcription factors in mammalian cells point to multiple roles in cancer. Exp Gerontol (2006) 1.77
FOXO forkhead transcription factors induce G(2)-M checkpoint in response to oxidative stress. J Biol Chem (2002) 1.76
Control of cyclin G2 mRNA expression by forkhead transcription factors: novel mechanism for cell cycle control by phosphoinositide 3-kinase and forkhead. Mol Cell Biol (2004) 1.76
Increased levels of forkhead box M1B transcription factor in transgenic mouse hepatocytes prevent age-related proliferation defects in regenerating liver. Proc Natl Acad Sci U S A (2001) 1.75
H2AX Phosphorylation: Its Role in DNA Damage Response and Cancer Therapy. J Nucleic Acids (2010) 1.69
The Forkhead box M1 protein regulates the transcription of the estrogen receptor alpha in breast cancer cells. J Biol Chem (2006) 1.68
The Mre11/Rad50/Nbs1 complex and its role as a DNA double-strand break sensor for ATM. Cell Cycle (2005) 1.67
Foxo3a inhibits cardiomyocyte hypertrophy through transactivating catalase. J Biol Chem (2008) 1.61
Functional interaction between FOXO3a and ATM regulates DNA damage response. Nat Cell Biol (2008) 1.58
FoxM1 regulates transcription of JNK1 to promote the G1/S transition and tumor cell invasiveness. J Biol Chem (2008) 1.58
DNA methyltransferases, DNA damage repair, and cancer. Adv Exp Med Biol (2013) 1.57
Gefitinib (Iressa) represses FOXM1 expression via FOXO3a in breast cancer. Mol Cancer Ther (2009) 1.56
Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites. J Cell Biol (2009) 1.55
Regulation of FOXO protein stability via ubiquitination and proteasome degradation. Biochim Biophys Acta (2011) 1.52
FOXM1 upregulation is an early event in human squamous cell carcinoma and it is enhanced by nicotine during malignant transformation. PLoS One (2009) 1.48
Caspase-2 deficiency enhances aging-related traits in mice. Mech Ageing Dev (2006) 1.46
Harnessing the complexity of DNA-damage response pathways to improve cancer treatment outcomes. Oncogene (2010) 1.45
p53-dependent inhibition of FKHRL1 in response to DNA damage through protein kinase SGK1. Proc Natl Acad Sci U S A (2004) 1.43
Deacetylation of FOXO3 by SIRT1 or SIRT2 leads to Skp2-mediated FOXO3 ubiquitination and degradation. Oncogene (2011) 1.38
Epstein-Barr virus latent membrane protein 1 induces micronucleus formation, represses DNA repair and enhances sensitivity to DNA-damaging agents in human epithelial cells. Oncogene (2004) 1.38
MUC1 oncoprotein activates the FOXO3a transcription factor in a survival response to oxidative stress. J Biol Chem (2004) 1.33
Early events in the mammalian response to DNA double-strand breaks. Mutagenesis (2008) 1.33
ATM and p53 regulate FOXM1 expression via E2F in breast cancer epirubicin treatment and resistance. Mol Cancer Ther (2011) 1.32
NBS1 and its functional role in the DNA damage response. DNA Repair (Amst) (2004) 1.30
Strategies for control of trachoma: observational study with quantitative PCR. Lancet (2003) 3.40
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Estimating household and community transmission of ocular Chlamydia trachomatis. PLoS Negl Trop Dis (2009) 1.52
Epidemiology of ocular surface squamous neoplasia in Africa. Trop Med Int Health (2013) 1.50
When can antibiotic treatments for trachoma be discontinued? Graduating communities in three African countries. PLoS Negl Trop Dis (2009) 1.36
Trichiasis surgery in The Gambia: a 4-year prospective study. Invest Ophthalmol Vis Sci (2010) 1.27
The clinical phenotype of trachomatous trichiasis in Ethiopia: not all trichiasis is due to entropion. Invest Ophthalmol Vis Sci (2011) 1.26
A coding polymorphism in matrix metalloproteinase 9 reduces risk of scarring sequelae of ocular Chlamydia trachomatis infection. BMC Med Genet (2006) 1.21
Trachoma: protective and pathogenic ocular immune responses to Chlamydia trachomatis. PLoS Negl Trop Dis (2013) 1.20
Absorbable versus silk sutures for surgical treatment of trachomatous trichiasis in Ethiopia: a randomised controlled trial. PLoS Med (2011) 1.18
Trachomatous trichiasis and its management in endemic countries. Surv Ophthalmol (2012) 1.13
The development of an age-structured model for trachoma transmission dynamics, pathogenesis and control. PLoS Negl Trop Dis (2009) 1.12
Clearing the backlog: trichiasis surgeon retention and productivity in northern Ethiopia. PLoS Negl Trop Dis (2011) 1.11
Surgery versus epilation for the treatment of minor trichiasis in Ethiopia: a randomised controlled noninferiority trial. PLoS Med (2011) 1.09
Bacterial infection in scarring trachoma. Invest Ophthalmol Vis Sci (2011) 1.07
Human conjunctival transcriptome analysis reveals the prominence of innate defense in Chlamydia trachomatis infection. Infect Immun (2010) 1.07
Cataract surgery in Southern Ethiopia: distribution, rates and determinants of service provision. BMC Health Serv Res (2013) 1.05
Chlamydia trachomatis ompA variants in trachoma: what do they tell us? PLoS Negl Trop Dis (2008) 1.03
Pathway-focused arrays reveal increased matrix metalloproteinase-7 (matrilysin) transcription in trachomatous trichiasis. Invest Ophthalmol Vis Sci (2010) 1.02
Targeting antibiotics to households for trachoma control. PLoS Negl Trop Dis (2010) 1.00
Epilation for trachomatous trichiasis and the risk of corneal opacification. Ophthalmology (2011) 0.98
In vivo confocal microscopy in scarring trachoma. Ophthalmology (2011) 0.95
Innate immune responses and modified extracellular matrix regulation characterize bacterial infection and cellular/connective tissue changes in scarring trachoma. Infect Immun (2011) 0.93
Conjunctival MicroRNA expression in inflammatory trachomatous scarring. PLoS Negl Trop Dis (2013) 0.93
Why do people not attend for treatment for trachomatous trichiasis in Ethiopia? A study of barriers to surgery. PLoS Negl Trop Dis (2012) 0.93
Epilepsy in Tanzanian children: association with perinatal events and other risk factors. Epilepsia (2012) 0.93
The outcome of trachomatous trichiasis surgery in Ethiopia: risk factors for recurrence. PLoS Negl Trop Dis (2013) 0.93
Using a nonparametric multilevel latent Markov model to evaluate diagnostics for trachoma. Am J Epidemiol (2013) 0.91
A monoclonal antibody to the human HER3 receptor inhibits Neuregulin 1-beta binding and co-operates with Herceptin in inhibiting the growth of breast cancer derived cell lines. Breast Cancer Res Treat (2011) 0.88
XIAP and P-glycoprotein co-expression is related to imatinib resistance in chronic myeloid leukemia cells. Leuk Res (2013) 0.88
Chlamydial positivity of nasal discharge at baseline is associated with ocular chlamydial positivity 2 months following azithromycin treatment. Invest Ophthalmol Vis Sci (2006) 0.86
In vivo confocal microscopy of trachoma in relation to normal tarsal conjunctiva. Ophthalmology (2010) 0.85
Posterior segment eye disease in sub-Saharan Africa: review of recent population-based studies. Trop Med Int Health (2014) 0.85
Eyescores: an open platform for secure electronic data and photographic evidence collection in ophthalmological field studies. Br J Ophthalmol (2012) 0.84
In vivo confocal microscopy and histopathology of the conjunctiva in trachomatous scarring and normal tissue: a systematic comparison. Br J Ophthalmol (2013) 0.81
Quality assurance in trichiasis surgery: a methodology. Br J Ophthalmol (2010) 0.81
Co-morbidity of epilepsy in Tanzanian children: a community-based case-control study. Seizure (2011) 0.80
Doxycycline prevents matrix remodeling and contraction by trichiasis-derived conjunctival fibroblasts. Invest Ophthalmol Vis Sci (2013) 0.79
Phosphorylated Crkl reduction levels are associated with the lowest P-glycoprotein activity levels in cells from chronic myeloid leukemia patients. Leuk Res (2013) 0.78
Ocular rhinosporidiosis mimicking conjunctival squamous papilloma in Kenya - a case report. BMC Ophthalmol (2014) 0.75
New DVD supports trachoma surgery training. Community Eye Health (2011) 0.75
In Vitro Methods for Studying the Mechanisms of Resistance to DNA-Damaging Therapeutic Drugs. Methods Mol Biol (2016) 0.75
Erratum to: In Vitro Methods for Studying the Mechanisms of Resistance to DNA-Damaging Therapeutic Drugs. Methods Mol Biol (2016) 0.75